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383392-66-3,MFCD00469145
Catalog No.:AA00C6H8

383392-66-3 | Uc-112

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
≥98%(HPLC)
in stock  
$304.00   $213.00
- +
10mg
≥98%(HPLC)
in stock  
$445.00   $312.00
- +
25mg
≥98%(HPLC)
in stock  
$931.00   $652.00
- +
50mg
≥98%(HPLC)
in stock  
$1,559.00   $1,092.00
- +
100mg
≥98%(HPLC)
in stock  
$2,443.00   $1,710.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00C6H8
Chemical Name:
Uc-112
CAS Number:
383392-66-3
Molecular Formula:
C22H24N2O2
Molecular Weight:
348.4382
MDL Number:
MFCD00469145
SMILES:
Oc1c(CN2CCCC2)cc(c2c1nccc2)COCc1ccccc1
Properties
Computed Properties
 
Complexity:
420  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
26  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0  
Rotatable Bond Count:
6  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
3.3  

Literature

Title: Discovery of novel second mitochondria-derived activator of caspase mimetics as selective inhibitor of apoptosis protein inhibitors.

Journal: The Journal of pharmacology and experimental therapeutics 20140501

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Wang J, et al. Discovery of novel second mitochondria-derived activator of caspase mimetics as selective inhibitor of apoptosis protein inhibitors. J Pharmacol Exp Ther. 2014 May;349(2):319-29.

Title: Qinghui Wang, et al. Synthesis and biological evaluation of indole-based UC-112 analogs as potent and selective survivin inhibitors. Eur J Med Chem

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477567-49-0

477567-49-0
Tags:383392-66-3 Molecular Formula|383392-66-3 MDL|383392-66-3 SMILES|383392-66-3 Uc-112
Catalog No.: AA00C6H8
383392-66-3,MFCD00469145
383392-66-3 | Uc-112
Pack Size： 5mg
Purity： ≥98%(HPLC)
in stock
$304.00 $213.00
Pack Size： 10mg
Purity： ≥98%(HPLC)
in stock
$445.00 $312.00
Pack Size： 25mg
Purity： ≥98%(HPLC)
in stock
$931.00 $652.00
Pack Size： 50mg
Purity： ≥98%(HPLC)
in stock
$1,559.00 $1,092.00
Pack Size： 100mg
Purity： ≥98%(HPLC)
in stock
$2,443.00 $1,710.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA00C6H8
Chemical Name: Uc-112
CAS Number: 383392-66-3
Molecular Formula: C22H24N2O2
Molecular Weight: 348.4382
MDL Number: MFCD00469145
SMILES: Oc1c(CN2CCCC2)cc(c2c1nccc2)COCc1ccccc1
Properties
Complexity: 420  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 26  
Hydrogen Bond Acceptor Count: 4  
Hydrogen Bond Donor Count: 1  
Isotope Atom Count: 0  
Rotatable Bond Count: 6  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 3.3  
Literature fold

Title: Discovery of novel second mitochondria-derived activator of caspase mimetics as selective inhibitor of apoptosis protein inhibitors.

Journal: The Journal of pharmacology and experimental therapeutics20140501

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology20060501

Title: Wang J, et al. Discovery of novel second mitochondria-derived activator of caspase mimetics as selective inhibitor of apoptosis protein inhibitors. J Pharmacol Exp Ther. 2014 May;349(2):319-29.

Title: Qinghui Wang, et al. Synthesis and biological evaluation of indole-based UC-112 analogs as potent and selective survivin inhibitors. Eur J Med Chem

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