39012-20-9,MFCD00135962
Catalog No.:AA00BYDA

39012-20-9 | Picroside ii

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
95%
in stock  
$8.00   $6.00
- +
10mg
95%
in stock  
$43.00   $31.00
- +
25mg
95%
in stock  
$52.00   $37.00
- +
50mg
95%
in stock  
$102.00   $72.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00BYDA
Chemical Name:
Picroside ii
CAS Number:
39012-20-9
Molecular Formula:
C23H28O13
Molecular Weight:
512.4606
MDL Number:
MFCD00135962
SMILES:
OCC1OC(OC2OC=CC3C2C2(CO)OC2C3OC(=O)c2ccc(c(c2)OC)O)C(C(C1O)O)O
Properties
Computed Properties
 
Complexity:
839  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
5  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
36  
Hydrogen Bond Acceptor Count:
13  
Hydrogen Bond Donor Count:
6  
Isotope Atom Count:
0  
Rotatable Bond Count:
8  
Undefined Atom Stereocenter Count:
6  
Undefined Bond Stereocenter Count:
0  
XLogP3:
-1.4  

Literature

Title: The protective effect of picroside II against hypoxia/reoxygenation injury in neonatal rat cardiomyocytes.

Journal: Pharmaceutical biology 20121001

Title: Picroside II protects cardiomyocytes from hypoxia/reoxygenation-induced apoptosis by activating the PI3K/Akt and CREB pathways.

Journal: International journal of molecular medicine 20120801

Title: TLC densitometric quantification of picrosides (picroside-I and picroside-II) in Picrorhiza kurroa and its substitute Picrorhiza scrophulariiflora and their antioxidant studies.

Journal: Biomedical chromatography : BMC 20120101

Title: Primary study for the therapeutic dose and time window of picroside II in treating cerebral ischemic injury in rats.

Journal: International journal of molecular sciences 20120101

Title: Assessment of UDP-glucuronosyltransferase catalyzed formation of Picroside II glucuronide in microsomes of different species and recombinant UGTs.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20110701

Title: Online HPLC-DPPH method for antioxidant activity of Picrorhiza kurroa Royle ex Benth. and characterization of kutkoside by ultra-performance LC-electrospray ionization quadrupole time-of-flight mass spectrometry.

Journal: Indian journal of experimental biology 20100301

Title: Anti-inflammation effects of picroside 2 in cerebral ischemic injury rats.

Journal: Behavioral and brain functions : BBF 20100101

Title: Neuroprotective properties of picroside II in a rat model of focal cerebral ischemia.

Journal: International journal of molecular sciences 20100101

Title: Simultaneous determination of sugars and picrosides in Picrorhiza species using ultrasonic extraction and high-performance liquid chromatography with evaporative light scattering detection.

Journal: Journal of chromatography. A 20080620

Title: A sensitive and selective RP-HPLC method for simultaneous determination of picroside-I and picroside-II in rat plasma and its application in pharmacokinetics studies.

Journal: Journal of separation science 20071001

Title: The neuroprotective effect of picroside II from hu-huang-lian against oxidative stress.

Journal: The American journal of Chinese medicine 20070101

Title: Synergistic protective effect of picroside II and NGF on PC12 cells against oxidative stress induced by H2O2.

Journal: Pharmacological reports : PR 20070101

Title: Anti-lipid peroxidation and protection of liver mitochondria against injuries by picroside II.

Journal: World journal of gastroenterology 20050628

Title: Inhibitory effect of picroside II on hepatocyte apoptosis.

Journal: Acta pharmacologica Sinica 20050601

Title: Determination of picroside II in dog plasma by HPLC and its application in a pharmacokinetics study.

Journal: Biomedical chromatography : BMC 20050501

Title: Picrosides I and II, selective enhancers of the mitogen-activated protein kinase-dependent signaling pathway in the action of neuritogenic substances on PC12D cells.

Journal: Life sciences 20020830

Title: Huang Y, et al. Picroside II protects against sepsis via suppressing inflammation in mice. Am J Transl Res. 2016 Dec 15;8(12):5519-5531. eCollection 2016.

Title: Zhai L, et al. Picroside II protects the blood-brain barrier by inhibiting the oxidative signaling pathway in cerebral ischemia-reperfusion injury. PLoS One. 2017 Apr 7;12(4):e0174414.

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SDS
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Tags:39012-20-9 Molecular Formula|39012-20-9 MDL|39012-20-9 SMILES|39012-20-9 Picroside ii
Catalog No.: AA00BYDA
39012-20-9,MFCD00135962
39012-20-9 | Picroside ii
Pack Size: 1mg
Purity: 95%
in stock
$8.00 $6.00
Pack Size: 10mg
Purity: 95%
in stock
$43.00 $31.00
Pack Size: 25mg
Purity: 95%
in stock
$52.00 $37.00
Pack Size: 50mg
Purity: 95%
in stock
$102.00 $72.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA00BYDA
Chemical Name: Picroside ii
CAS Number: 39012-20-9
Molecular Formula: C23H28O13
Molecular Weight: 512.4606
MDL Number: MFCD00135962
SMILES: OCC1OC(OC2OC=CC3C2C2(CO)OC2C3OC(=O)c2ccc(c(c2)OC)O)C(C(C1O)O)O
Properties
Complexity: 839  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 5  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 36  
Hydrogen Bond Acceptor Count: 13  
Hydrogen Bond Donor Count: 6  
Isotope Atom Count: 0  
Rotatable Bond Count: 8  
Undefined Atom Stereocenter Count: 6  
Undefined Bond Stereocenter Count: 0  
XLogP3: -1.4  
Literature fold

Title: The protective effect of picroside II against hypoxia/reoxygenation injury in neonatal rat cardiomyocytes.

Journal: Pharmaceutical biology20121001

Title: Picroside II protects cardiomyocytes from hypoxia/reoxygenation-induced apoptosis by activating the PI3K/Akt and CREB pathways.

Journal: International journal of molecular medicine20120801

Title: TLC densitometric quantification of picrosides (picroside-I and picroside-II) in Picrorhiza kurroa and its substitute Picrorhiza scrophulariiflora and their antioxidant studies.

Journal: Biomedical chromatography : BMC20120101

Title: Primary study for the therapeutic dose and time window of picroside II in treating cerebral ischemic injury in rats.

Journal: International journal of molecular sciences20120101

Title: Assessment of UDP-glucuronosyltransferase catalyzed formation of Picroside II glucuronide in microsomes of different species and recombinant UGTs.

Journal: Xenobiotica; the fate of foreign compounds in biological systems20110701

Title: Online HPLC-DPPH method for antioxidant activity of Picrorhiza kurroa Royle ex Benth. and characterization of kutkoside by ultra-performance LC-electrospray ionization quadrupole time-of-flight mass spectrometry.

Journal: Indian journal of experimental biology20100301

Title: Anti-inflammation effects of picroside 2 in cerebral ischemic injury rats.

Journal: Behavioral and brain functions : BBF20100101

Title: Neuroprotective properties of picroside II in a rat model of focal cerebral ischemia.

Journal: International journal of molecular sciences20100101

Title: Simultaneous determination of sugars and picrosides in Picrorhiza species using ultrasonic extraction and high-performance liquid chromatography with evaporative light scattering detection.

Journal: Journal of chromatography. A20080620

Title: A sensitive and selective RP-HPLC method for simultaneous determination of picroside-I and picroside-II in rat plasma and its application in pharmacokinetics studies.

Journal: Journal of separation science20071001

Title: The neuroprotective effect of picroside II from hu-huang-lian against oxidative stress.

Journal: The American journal of Chinese medicine20070101

Title: Synergistic protective effect of picroside II and NGF on PC12 cells against oxidative stress induced by H2O2.

Journal: Pharmacological reports : PR20070101

Title: Anti-lipid peroxidation and protection of liver mitochondria against injuries by picroside II.

Journal: World journal of gastroenterology20050628

Title: Inhibitory effect of picroside II on hepatocyte apoptosis.

Journal: Acta pharmacologica Sinica20050601

Title: Determination of picroside II in dog plasma by HPLC and its application in a pharmacokinetics study.

Journal: Biomedical chromatography : BMC20050501

Title: Picrosides I and II, selective enhancers of the mitogen-activated protein kinase-dependent signaling pathway in the action of neuritogenic substances on PC12D cells.

Journal: Life sciences20020830

Title: Huang Y, et al. Picroside II protects against sepsis via suppressing inflammation in mice. Am J Transl Res. 2016 Dec 15;8(12):5519-5531. eCollection 2016.

Title: Zhai L, et al. Picroside II protects the blood-brain barrier by inhibiting the oxidative signaling pathway in cerebral ischemia-reperfusion injury. PLoS One. 2017 Apr 7;12(4):e0174414.

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