+1 858-523-8231
Login | Register
menu
AA Blocks, Building Blocks, Catalysts, Inhibitors
Login | Register
405554-55-4,MFCD16038645
Catalog No.:AA00BYEI

405554-55-4 | Sb590885

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$52.00   $37.00
- +
5mg
98%
in stock  
$129.00   $91.00
- +
10mg
98%
in stock  
$219.00   $154.00
- +
50mg
98%
in stock  
$557.00   $390.00
- +
250mg
98
in stock  
$2,522.00   $1,765.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00BYEI
Chemical Name:
Sb590885
CAS Number:
405554-55-4
Molecular Formula:
C27H27N5O2
Molecular Weight:
453.5356
MDL Number:
MFCD16038645
SMILES:
O/N=C\1/CCc2c1ccc(c2)c1nc([nH]c1c1ccncc1)c1ccc(cc1)OCCN(C)C
Properties
Properties
 
Form:
Solid  
Storage:
Keep in dry area;-20 ℃;  

Computed Properties
 
Complexity:
674  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
1  
Formal Charge:
0  
Heavy Atom Count:
34  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0  
Rotatable Bond Count:
7  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
4  

Literature

Title: King AJ, et al. Demonstration of a genetic therapeutic index for tumors expressing oncogenic BRAF by the kinase inhibitor SB-590885. Cancer Res, 2006, 66(23), 11100-11105.

Title: Takle AK, et al. The identification of potent and selective imidazole-based inhibitors of B-Raf kinase. Bioorg Med Chem Lett, 2006, 16(2), 378-381.

Title: Smalley KS, et al. Increased cyclin D1 expression can mediate BRAF inhibitor resistance in BRAF V600E-mutated melanomas. Mol Cancer Ther, 2008, 7(9), 2876-2883.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
Submit
SDS
Related Products of 405554-55-4
Building Blocks
More >
Historical Records
1955514-22-3

1955514-22-3

 946296-17-9

946296-17-9

 1351651-08-5

1351651-08-5
Tags:405554-55-4 Molecular Formula|405554-55-4 MDL|405554-55-4 SMILES|405554-55-4 Sb590885
Catalog No.: AA00BYEI
405554-55-4,MFCD16038645
405554-55-4 | Sb590885
Pack Size： 1mg
Purity： 98%
in stock
$52.00 $37.00
Pack Size： 5mg
Purity： 98%
in stock
$129.00 $91.00
Pack Size： 10mg
Purity： 98%
in stock
$219.00 $154.00
Pack Size： 50mg
Purity： 98%
in stock
$557.00 $390.00
Pack Size： 250mg
Purity： 98
in stock
$2,522.00 $1,765.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA00BYEI
Chemical Name: Sb590885
CAS Number: 405554-55-4
Molecular Formula: C27H27N5O2
Molecular Weight: 453.5356
MDL Number: MFCD16038645
SMILES: O/N=C\1/CCc2c1ccc(c2)c1nc([nH]c1c1ccncc1)c1ccc(cc1)OCCN(C)C
Properties
Form: Solid  
Storage: Keep in dry area;-20 ℃;  
Complexity: 674  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 1  
Formal Charge: 0  
Heavy Atom Count: 34  
Hydrogen Bond Acceptor Count: 6  
Hydrogen Bond Donor Count: 2  
Isotope Atom Count: 0  
Rotatable Bond Count: 7  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 4  
Related Products of of 405554-55-4
Building Blocks More >
399-67-7
399-67-7
7-Fluoro-1h-indole-2-carboxylic acid
AA00BYJM | MFCD02664429
401-73-0
401-73-0
3-(Trifluoromethyl)-2-pyrazolin-5-one
AA00BYOM | MFCD00052748
409110-07-2
409110-07-2
Thiazole-5-carbothioamide
AA00BYUO | MFCD06738990
42066-86-4
42066-86-4
2-Cyanophenyl isocyanate
AA00BYYL | MFCD00829130
38580-22-2
38580-22-2
2-(6-Methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acetic acid
AA00BZ3W | MFCD03795557
40137-29-9
40137-29-9
4-Chloro-2-methylbenzaldehyde
AA00BZ92 | MFCD02261735
42521-08-4
42521-08-4
2,6-Dichloroisonicotinoyl chloride
AA00BZEQ | MFCD00052639
32604-44-7
32604-44-7
4-N-NONYLPHENOL ACETATE
AA00BZKM | MFCD04112646
33174-08-2
33174-08-2
1-ISOBUTYLPIPERAZINE 2HCL
AA00BZPG | MFCD00039026
3528-45-8
3528-45-8
1-(4-Methoxybenzyl)-1h-pyrazol-5-amine
AA00BZW2 | MFCD03596770
Historical Records
1955514-22-3
1955514-22-3
946296-17-9
946296-17-9
1351651-08-5
1351651-08-5
Submit
© 2017 AA BLOCKS, INC. All rights reserved.