Name: Name:4-(Benzo[d]thiazol-2-yl)-N-methylaniline
Brand: AABLOCKS
SKU: AA00DIFR
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA00DIFR

Chemical Name: 4-(Benzo[d]thiazol-2-yl)-N-methylaniline

CAS Number: 439858-28-3

Molecular Formula: C14H12N2S

Molecular Weight: 240.3235

MDL Number: MFCD04974146

SMILES: CNc1ccc(cc1)c1nc2c(s1)cccc2

Properties

Complexity: 251

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 17

Hydrogen Bond Acceptor Count: 3

Hydrogen Bond Donor Count: 1

Isotope Atom Count: 0

Rotatable Bond Count: 2

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 4.2

Literature fold

Title: Aβ Imaging: feasible, pertinent, and vital to progress in Alzheimer's disease.

Journal: European journal of nuclear medicine and molecular imaging20120201

Title: Technical aspects of amyloid imaging for Alzheimer's disease.

Journal: Alzheimer's research & therapy20110101

Title: Amyloid imaging in the differential diagnosis of dementia: review and potential clinical applications.

Journal: Alzheimer's research & therapy20110101

Title: Synthesis and evaluation of stilbene derivatives as a potential imaging agent of amyloid plaques.

Journal: Bioorganic & medicinal chemistry20101115

Title: Near-field scanning optical microscopy measurements of fluorescent molecular probes binding to insulin amyloid fibrils.

Journal: The journal of physical chemistry. B20090903

Title: Regional analysis of FDG and PIB-PET images in normal aging, mild cognitive impairment, and Alzheimer's disease.

Journal: European journal of nuclear medicine and molecular imaging20081201

Title: Efficient radiosynthesis of carbon-11 labelled uncharged Thioflavin T derivatives using [11C]methyl triflate for beta-amyloid imaging in Alzheimer's Disease with PET.

Journal: Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine20050401

Title: Evidence for the presence of three distinct binding sites for the thioflavin T class of Alzheimer's disease PET imaging agents on beta-amyloid peptide fibrils.

Journal: The Journal of biological chemistry20050304

Title: Amyloid imaging probes are useful for detection of prion plaques and treatment of transmissible spongiform encephalopathies.

Journal: The Journal of general virology20040601

Title: Synthesis and evaluation of 11C-labeled 6-substituted 2-arylbenzothiazoles as amyloid imaging agents.

Journal: Journal of medicinal chemistry20030619

Title: The binding of 2-(4'-methylaminophenyl)benzothiazole to postmortem brain homogenates is dominated by the amyloid component.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20030315

Title: A lipophilic thioflavin-T derivative for positron emission tomography (PET) imaging of amyloid in brain.

Journal: Bioorganic & medicinal chemistry letters20020211

439858-28-3 | 4-(Benzo[d]thiazol-2-yl)-N-methylaniline