Title: Isothiocyanates from Wasabia japonica activate transient receptor potential ankyrin 1 channel.
Journal: Chemical senses20121101
Title: Molecular Mechanisms Underlying Anti-Inflammatory Actions of 6-(Methylsulfinyl)hexyl Isothiocyanate Derived from Wasabi (Wasabia japonica).
Journal: Advances in pharmacological sciences20120101
Title: Transthiocarbamoylation of proteins by thiolated isothiocyanates.
Journal: The Journal of biological chemistry20111209
Title: Dynamics of Nrf2 and Keap1 in ARE-mediated NQO1 expression by wasabi 6-(methylsulfinyl)hexyl isothiocyanate.
Journal: Journal of agricultural and food chemistry20111123
Title: Isothiocyanates reduce mercury accumulation via an Nrf2-dependent mechanism during exposure of mice to methylmercury.
Journal: Environmental health perspectives20110801
Title: Glycogen synthase kinase-3β inhibition of 6-(methylsulfinyl)hexyl isothiocyanate derived from wasabi (Wasabia japonica Matsum).
Journal: Bioscience, biotechnology, and biochemistry20110101
Title: Glutathione biosynthesis via activation of the nuclear factor E2-related factor 2 (Nrf2)--antioxidant-response element (ARE) pathway is essential for neuroprotective effects of sulforaphane and 6-(methylsulfinyl) hexyl isothiocyanate.
Journal: Journal of pharmacological sciences20110101
Title: Anti-oxidant and Anti-hypercholesterolemic Activities of Wasabia japonica.
Journal: Evidence-based complementary and alternative medicine : eCAM20101201
Title: Immunochemical detection of food-derived isothiocyanate as a lysine conjugate.
Journal: Bioscience, biotechnology, and biochemistry20100101
Title: Anti-nitric oxide production activity of isothiocyanates correlates with their polar surface area rather than their lipophilicity.
Journal: European journal of medicinal chemistry20091201
Title: Alkyl isothiocyanates suppress epidermal growth factor receptor kinase activity but augment tyrosine kinase activity.
Journal: Cancer epidemiology20091001
Title: The augmenting activity of 6-(methylsulfinyl)hexyl isothiocyanate on cellular glutathione levels is less sensitive to thiol compounds than its cytotoxic activity.
Journal: Bioscience, biotechnology, and biochemistry20090601
Title: A food-derived synergist of NGF signaling: identification of protein tyrosine phosphatase 1B as a key regulator of NGF receptor-initiated signal transduction.
Journal: Journal of neurochemistry20081201
Title: Detection of 6-(methylsulfinyl)hexyl isothiocyanate (6-MITC) and its conjugate with N-acetyl-L-cysteine (NAC) by high performance liquid chromatograpy-atmospheric pressure chemical ionization mass spectrometry (HPLC-MS/APCI).
Journal: Chemical & pharmaceutical bulletin20080501
Title: Effects of 6-(methylsulfinyl)hexyl isothiocyanate on cyclooxygenase-2 expression induced by lipopolysaccharide, interferon-gamma and 12-O-tetradecanoylphorbol-13-acetate.
Journal: Oncology reports20070101
Title: Preventive effect of oral administration of 6-(methylsulfinyl)hexyl isothiocyanate derived from wasabi (Wasabia japonica Matsum) against pulmonary metastasis of B16-BL6 mouse melanoma cells.
Journal: Cancer detection and prevention20060101
Title: Inhibition of lipopolysaccharide-induced cyclooxygenase-2 transcription by 6-(methylsulfinyl) hexyl isothiocyanate, a chemopreventive compound from Wasabia japonica (Miq.) Matsumura, in mouse macrophages.
Journal: Biochemical pharmacology20051205
Title: 6-(Methylsulfinyl)hexyl isothiocyanate suppresses inducible nitric oxide synthase expression through the inhibition of Janus kinase 2-mediated JNK pathway in lipopolysaccharide-activated murine macrophages.
Journal: Biochemical pharmacology20051015
Title: Nrf2 as a novel molecular target for chemoprevention.
Journal: Cancer letters20050628
Title: Effects of dietary chemopreventive phytochemicals on P-glycoprotein function.
Journal: Biochemical and biophysical research communications20050218
Title: Selective sensitivity to wasabi-derived 6-(methylsulfinyl)hexyl isothiocyanate of human breast cancer and melanoma cell lines studied in vitro.
Journal: Cancer detection and prevention20050101
Title: Identification of 6-methylsulfinylhexyl isothiocyanate as an apoptosis-inducing component in wasabi.
Journal: Phytochemistry20030301
Title: Augmented gene expression of quinone reductase by 6-(methylsulfinyl)hexyl isothiocyanate through avoiding its cytotoxicity.
Journal: Anticancer research20030101
Title: A sulforaphane analogue that potently activates the Nrf2-dependent detoxification pathway.
Journal: The Journal of biological chemistry20020201
Title: Tanaka Y, et al. 6-Methylsulfinylhexyl isothiocyanate prevents high-fat diet-induced fatty liver but fails to attenuate hepatic iron accumulation in mice. Clin Exp Pharmacol Physiol. 2016 Nov;43(11):1153-1156.
Title: Okamoto T, et al. 6-Methylsulfinylhexyl isothiocyanate modulates endothelial cell function and suppresses leukocyte adhesion. J Nat Med. 2014 Jan;68(1):144-53.
