Title: Inhibition of bladder cancer by broccoli isothiocyanates sulforaphane and erucin: characterization, metabolism, and interconversion.
Journal: Molecular nutrition & food research20121101
Title: The naturally occurring aliphatic isothiocyanates sulforaphane and erucin are weak agonists but potent non-competitive antagonists of the aryl hydrocarbon receptor.
Journal: Archives of toxicology20121001
Title: Neuroprotective effects of erucin against 6-hydroxydopamine-induced oxidative damage in a dopaminergic-like neuroblastoma cell line.
Journal: International journal of molecular sciences20120101
Title: Bioavailability and inter-conversion of sulforaphane and erucin in human subjects consuming broccoli sprouts or broccoli supplement in a cross-over study design.
Journal: Pharmacological research20111101
Title: Comparison of isothiocyanate metabolite levels and histone deacetylase activity in human subjects consuming broccoli sprouts or broccoli supplement.
Journal: Journal of agricultural and food chemistry20111026
Title: Induction of epoxide hydrolase and glucuronosyl transferase by isothiocyanates and intact glucosinolates in precision-cut rat liver slices: importance of side-chain substituent and chirality.
Journal: Archives of toxicology20110801
Title: Phytochemical analysis and antimicrobial activity of Cardaria draba (L.) Desv. volatiles.
Journal: Chemistry & biodiversity20110601
Title: Up-regulation of cytochrome P450 and phase II enzyme systems in rat precision-cut rat lung slices by the intact glucosinolates, glucoraphanin and glucoerucin.
Journal: Lung cancer (Amsterdam, Netherlands)20110301
Title: Selective depletion of mutant p53 by cancer chemopreventive isothiocyanates and their structure-activity relationships.
Journal: Journal of medicinal chemistry20110210
Title: Exposure to isothiocyanates suppresses urinary mutagenicity in rats treated with heterocyclic amine IQ: lack of association with CYP1 activity.
Journal: Nutrition and cancer20110101
Title: Intact glucosinolates modulate hepatic cytochrome P450 and phase II conjugation activities and may contribute directly to the chemopreventive activity of cruciferous vegetables.
Journal: Toxicology20101109
Title: Comparison of the apoptosis-inducing capability of sulforaphane analogues in human colon cancer cells.
Journal: Anticancer research20100901
Title: Biological profile of erucin: a new promising anticancer agent from cruciferous vegetables.
Journal: Toxins20100401
Title: Enhancement of arsenic trioxide cytotoxicity by dietary isothiocyanates in human leukemic cells via a reactive oxygen species-dependent mechanism.
Journal: Leukemia research20100201
Title: Mustard oil in 'Shibori Daikon' a variety of Japanese radish, selectively inhibits the proliferation of H-ras-transformed 3Y1 cells.
Journal: Bioscience, biotechnology, and biochemistry20091001
Title: Erucin, a new promising cancer chemopreventive agent from rocket salads, shows anti-proliferative activity on human lung carcinoma A549 cells.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association20090701
Title: The aliphatic isothiocyanates erucin and sulforaphane do not effectively up-regulate NAD(P)H:quinone oxidoreductase (NQO1) in human liver compared with rat.
Journal: Molecular nutrition & food research20090701
Title: Potency of isothiocyanates to induce luciferase reporter gene expression via the electrophile-responsive element from murine glutathione S-transferase Ya.
Journal: Toxicology in vitro : an international journal published in association with BIBRA20090601
Title: MTBITC mediates cell cycle arrest and apoptosis induction in human HepG2 cells despite its rapid degradation kinetics in the in vitro model.
Journal: Environmental and molecular mutagenesis20090401
Title: Modulation of rat pulmonary carcinogen-metabolising enzyme systems by the isothiocyanates erucin and sulforaphane.
Journal: Chemico-biological interactions20090127
Title: Potential skin antiinflammatory effects of 4-methylthiobutylisothiocyanate (MTBI) isolated from rocket (Eruca sativa) seeds.
Journal: BioFactors (Oxford, England)20090101
Title: Up-regulation of the CYP1 family in rat and human liver by the aliphatic isothiocyanates erucin and sulforaphane.
Journal: Toxicology20081030
Title: Modulation of rat hepatic and pulmonary cytochromes P450 and phase II enzyme systems by erucin, an isothiocyanate structurally related to sulforaphane.
Journal: Journal of agricultural and food chemistry20080910
Title: Antigenotoxic properties of Eruca sativa (rocket plant), erucin and erysolin in human hepatoma (HepG2) cells towards benzo(a)pyrene and their mode of action.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association20080701
Title: Sulforaphane and erucin increase MRP1 and MRP2 in human carcinoma cell lines.
Journal: The Journal of nutritional biochemistry20080401
Title: Role of PI3K/Akt and MEK/ERK signaling pathways in sulforaphane- and erucin-induced phase II enzymes and MRP2 transcription, G2/M arrest and cell death in Caco-2 cells.
Journal: Biochemical pharmacology20050601
Title: Micronucleus formation and induction of apoptosis by different isothiocyanates and a mixture of isothiocyanates in human lymphocyte cultures.
Journal: Mutation research20050404
Title: Sulforaphane, erucin, and iberin up-regulate thioredoxin reductase 1 expression in human MCF-7 cells.
Journal: Journal of agricultural and food chemistry20050309
Title: Isothiocyanates as novel cytotoxic and cytostatic agents: molecular pathway on human transformed and non-transformed cells.
Journal: Biochemical pharmacology20040915
Title: The new isothiocyanate 4-(methylthio)butylisothiocyanate selectively affects cell-cycle progression and apoptosis induction of human leukemia cells.
Journal: Investigational new drugs20040401
Title: Aroma compound analysis of Eruca sativa (Brassicaceae) SPME headspace leaf samples using GC, GC-MS, and olfactometry.
Journal: Journal of agricultural and food chemistry20020731
Title: Monitoring of isothiocyanates emanating from Arabidopsis thaliana upon paraquat spraying.
Journal: Journal of chromatography. A20010330
Title: A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure.
Journal: Proceedings of the National Academy of Sciences of the United States of America19920315
