452311-56-7
Catalog No.:AA01EPQB

452311-56-7 | 10-β-D-glucopyranosyl-1,8-dihydroxy-3-(hydroxymethyl)-9(10H)-anthracenone

Pack Size
Purity
Availability
Price(USD)
Quantity
  
500mg
≥95%
in stock  
$46.00   $32.00
- +
1g
≥95%
in stock  
$88.00   $61.00
- +
5g
≥95%
in stock  
$373.00   $261.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA01EPQB
Chemical Name:
10-β-D-glucopyranosyl-1,8-dihydroxy-3-(hydroxymethyl)-9(10H)-anthracenone
CAS Number:
452311-56-7
Molecular Formula:
C21H22O9
Molecular Weight:
418.3940
SMILES:
OCc1cc(O)c2c(c1)C([C@@H]1O[C@H](CO)[C@H]([C@@H]([C@H]1O)O)O)c1c(C2=O)c(O)ccc1
Properties
Computed Properties
 
Complexity:
630  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
5  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
7  
Isotope Atom Count:
0  
Rotatable Bond Count:
3  
Undefined Atom Stereocenter Count:
1  
Undefined Bond Stereocenter Count:
0  
XLogP3:
-0.1  

Literature

Title: From the Cover: Aloin, a Component of the Aloe Vera Plant Leaf, Induces Pathological Changes and Modulates the Composition of Microbiota in the Large Intestines of F344/N Male Rats.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20170801

Title: On the novel action of melanolysis by a leaf extract of Aloe vera and its active ingredient aloin, potent skin depigmenting agents.

Journal: Planta medica 20120501

Title: Microwave-assisted extraction performed in low temperature and in vacuo for the extraction of labile compounds in food samples.

Journal: Analytica chimica acta 20120127

Title: In vitro accelerated mass propagation and ex vitro evaluation of Aloe vera L. with aloin content and superoxide dismutase activity.

Journal: Natural product research 20110801

Title: Selective determination of aloin in different matrices by HPTLC densitometry in fluorescence mode.

Journal: Journal of pharmaceutical and biomedical analysis 20110125

Title: Hypericins and thioredoxin reductase: Biochemical and docking studies disclose the molecular basis for effective inhibition by naphthodianthrones.

Journal: Bioorganic & medicinal chemistry 20110101

Title: Probenecid inhibits the human bitter taste receptor TAS2R16 and suppresses bitter perception of salicin.

Journal: PloS one 20110101

Title: Synthesis of cytotoxic and antioxidant Schiff's base analogs of aloin.

Journal: Journal of Asian natural products research 20100501

Title: Ultraviolet light absorption of an ophthalmic formulation with Aloe extracts.

Journal: Natural product communications 20090901

Title: High-affinity, non-nucleotide-derived competitive antagonists of platelet P2Y12 receptors.

Journal: Journal of medicinal chemistry 20090625

Title: Evaluation of aloin and aloe-emodin as anti-inflammatory agents in aloe by using murine macrophages.

Journal: Bioscience, biotechnology, and biochemistry 20090423

Title: Aloin induces apoptosis in Jurkat cells.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20080301

Title: Effect of vehicles on topical application of aloe vera and arnica montana components.

Journal: Drug delivery 20071001

Title: Specific alleles of bitter receptor genes influence human sensitivity to the bitterness of aloin and saccharin.

Journal: Current biology : CB 20070821

Title: Photo-irradiation of Aloe vera by UVA--formation of free radicals, singlet oxygen, superoxide, and induction of lipid peroxidation.

Journal: Toxicology letters 20070130

Title: Determination of the anthraquinones aloe-emodin and aloin-A by liquid chromatography with mass spectrometric and diode array detection.

Journal: Journal of AOAC International 20070101

Title: [Ultracytochemical studies of aloin in Aloe arborescens leaves].

Journal: Fen zi xi bao sheng wu xue bao = Journal of molecular cell biology 20060201

Title: Cytotoxicity of a natural anthraquinone (Aloin) against human breast cancer cell lines with and without ErbB-2: topoisomerase IIalpha coamplification.

Journal: Cancer biology & therapy 20060101

Title: [Preparative separation of aloin diastereoisomers by high-speed countercurrent chromatography combined with silica gel column chromatography].

Journal: Se pu = Chinese journal of chromatography 20060101

Title: Spectroscopic characterization of effective components anthraquinones in Chinese medicinal herbs binding with serum albumins.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20051101

Title: DNA ploidy and S phase fraction of breast and ovarian tumor cells treated with a natural anthracycline analog (aloin).

Journal: Cancer biology & therapy 20050101

Title: Analysis of the anthraquinones aloe-emodin and aloin by gas chromatography/mass spectrometry.

Journal: International immunopharmacology 20041220

Title: [Determination of aloin content in callus of Aloe vera var. chinensis].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20040901

Title: Differential and special properties of the major human UGT1-encoded gastrointestinal UDP-glucuronosyltransferases enhance potential to control chemical uptake.

Journal: The Journal of biological chemistry 20040109

Title: Radical-scavenging effects of Aloe arborescens Miller on prevention of pancreatic islet B-cell destruction in rats.

Journal: Journal of ethnopharmacology 20031101

Title: [Relationship between antibacterial activity of aloe and its anthaquinone compounds].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20031101

Title: [Development of aloin cells and accumulation of anthraquinone in aloe leaf].

Journal: Shi yan sheng wu xue bao 20031001

Title: Inhibition of collagenase and metalloproteinases by aloins and aloe gel.

Journal: Life sciences 20030103

Title: Inhibition of azoxymethane-induced DNA adduct formation by Aloe arborescens var. natalensis.

Journal: Asian Pacific journal of cancer prevention : APJCP 20030101

Title: Aloin, cinnamic acid and sophorcarpidine are potent inhibitors of tyrosinase.

Journal: Chinese medical journal 20021201

Title: Hypotensive effect of chemical constituents from Aloe barbadensis.

Journal: Planta medica 20011101

Title: Aloe exudate: characterization by reversed phase HPLC and headspace GC-MS.

Journal: Journal of agricultural and food chemistry 20011001

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Related Products of 452311-56-7
Tags:452311-56-7 Molecular Formula|452311-56-7 MDL|452311-56-7 SMILES|452311-56-7 10-β-D-glucopyranosyl-1,8-dihydroxy-3-(hydroxymethyl)-9(10H)-anthracenone
Catalog No.: AA01EPQB
452311-56-7
452311-56-7 | 10-β-D-glucopyranosyl-1,8-dihydroxy-3-(hydroxymethyl)-9(10H)-anthracenone
Pack Size: 500mg
Purity: ≥95%
in stock
$46.00 $32.00
Pack Size: 1g
Purity: ≥95%
in stock
$88.00 $61.00
Pack Size: 5g
Purity: ≥95%
in stock
$373.00 $261.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA01EPQB
Chemical Name: 10-β-D-glucopyranosyl-1,8-dihydroxy-3-(hydroxymethyl)-9(10H)-anthracenone
CAS Number: 452311-56-7
Molecular Formula: C21H22O9
Molecular Weight: 418.3940
SMILES: OCc1cc(O)c2c(c1)C([C@@H]1O[C@H](CO)[C@H]([C@@H]([C@H]1O)O)O)c1c(C2=O)c(O)ccc1
Properties
Complexity: 630  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 5  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 30  
Hydrogen Bond Acceptor Count: 9  
Hydrogen Bond Donor Count: 7  
Isotope Atom Count: 0  
Rotatable Bond Count: 3  
Undefined Atom Stereocenter Count: 1  
Undefined Bond Stereocenter Count: 0  
XLogP3: -0.1  
Literature fold

Title: From the Cover: Aloin, a Component of the Aloe Vera Plant Leaf, Induces Pathological Changes and Modulates the Composition of Microbiota in the Large Intestines of F344/N Male Rats.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20170801

Title: On the novel action of melanolysis by a leaf extract of Aloe vera and its active ingredient aloin, potent skin depigmenting agents.

Journal: Planta medica20120501

Title: Microwave-assisted extraction performed in low temperature and in vacuo for the extraction of labile compounds in food samples.

Journal: Analytica chimica acta20120127

Title: In vitro accelerated mass propagation and ex vitro evaluation of Aloe vera L. with aloin content and superoxide dismutase activity.

Journal: Natural product research20110801

Title: Selective determination of aloin in different matrices by HPTLC densitometry in fluorescence mode.

Journal: Journal of pharmaceutical and biomedical analysis20110125

Title: Hypericins and thioredoxin reductase: Biochemical and docking studies disclose the molecular basis for effective inhibition by naphthodianthrones.

Journal: Bioorganic & medicinal chemistry20110101

Title: Probenecid inhibits the human bitter taste receptor TAS2R16 and suppresses bitter perception of salicin.

Journal: PloS one20110101

Title: Synthesis of cytotoxic and antioxidant Schiff's base analogs of aloin.

Journal: Journal of Asian natural products research20100501

Title: Ultraviolet light absorption of an ophthalmic formulation with Aloe extracts.

Journal: Natural product communications20090901

Title: High-affinity, non-nucleotide-derived competitive antagonists of platelet P2Y12 receptors.

Journal: Journal of medicinal chemistry20090625

Title: Evaluation of aloin and aloe-emodin as anti-inflammatory agents in aloe by using murine macrophages.

Journal: Bioscience, biotechnology, and biochemistry20090423

Title: Aloin induces apoptosis in Jurkat cells.

Journal: Toxicology in vitro : an international journal published in association with BIBRA20080301

Title: Effect of vehicles on topical application of aloe vera and arnica montana components.

Journal: Drug delivery20071001

Title: Specific alleles of bitter receptor genes influence human sensitivity to the bitterness of aloin and saccharin.

Journal: Current biology : CB20070821

Title: Photo-irradiation of Aloe vera by UVA--formation of free radicals, singlet oxygen, superoxide, and induction of lipid peroxidation.

Journal: Toxicology letters20070130

Title: Determination of the anthraquinones aloe-emodin and aloin-A by liquid chromatography with mass spectrometric and diode array detection.

Journal: Journal of AOAC International20070101

Title: [Ultracytochemical studies of aloin in Aloe arborescens leaves].

Journal: Fen zi xi bao sheng wu xue bao = Journal of molecular cell biology20060201

Title: Cytotoxicity of a natural anthraquinone (Aloin) against human breast cancer cell lines with and without ErbB-2: topoisomerase IIalpha coamplification.

Journal: Cancer biology & therapy20060101

Title: [Preparative separation of aloin diastereoisomers by high-speed countercurrent chromatography combined with silica gel column chromatography].

Journal: Se pu = Chinese journal of chromatography20060101

Title: Spectroscopic characterization of effective components anthraquinones in Chinese medicinal herbs binding with serum albumins.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy20051101

Title: DNA ploidy and S phase fraction of breast and ovarian tumor cells treated with a natural anthracycline analog (aloin).

Journal: Cancer biology & therapy20050101

Title: Analysis of the anthraquinones aloe-emodin and aloin by gas chromatography/mass spectrometry.

Journal: International immunopharmacology20041220

Title: [Determination of aloin content in callus of Aloe vera var. chinensis].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials20040901

Title: Differential and special properties of the major human UGT1-encoded gastrointestinal UDP-glucuronosyltransferases enhance potential to control chemical uptake.

Journal: The Journal of biological chemistry20040109

Title: Radical-scavenging effects of Aloe arborescens Miller on prevention of pancreatic islet B-cell destruction in rats.

Journal: Journal of ethnopharmacology20031101

Title: [Relationship between antibacterial activity of aloe and its anthaquinone compounds].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20031101

Title: [Development of aloin cells and accumulation of anthraquinone in aloe leaf].

Journal: Shi yan sheng wu xue bao20031001

Title: Inhibition of collagenase and metalloproteinases by aloins and aloe gel.

Journal: Life sciences20030103

Title: Inhibition of azoxymethane-induced DNA adduct formation by Aloe arborescens var. natalensis.

Journal: Asian Pacific journal of cancer prevention : APJCP20030101

Title: Aloin, cinnamic acid and sophorcarpidine are potent inhibitors of tyrosinase.

Journal: Chinese medical journal20021201

Title: Hypotensive effect of chemical constituents from Aloe barbadensis.

Journal: Planta medica20011101

Title: Aloe exudate: characterization by reversed phase HPLC and headspace GC-MS.

Journal: Journal of agricultural and food chemistry20011001

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