466-07-9,MFCD00869436
Catalog No.:AA00D8Q7

466-07-9 | NERIIFOLIN

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
99%
1 week  
$765.00   $535.00
- +
10mg
99%
1 week  
$1,193.00   $835.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00D8Q7
Chemical Name:
NERIIFOLIN
CAS Number:
466-07-9
Molecular Formula:
C30H46O8
Molecular Weight:
534.6814
MDL Number:
MFCD00869436
SMILES:
CO[C@H]1[C@H](O)[C@H](O[C@H]2CC[C@]3([C@@H](C2)CC[C@@H]2[C@@H]3CC[C@]3([C@]2(O)CC[C@@H]3C2=CC(=O)OC2)C)C)O[C@H]([C@@H]1O)C
Properties
Computed Properties
 
Complexity:
968  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
13  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
38  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0  
Rotatable Bond Count:
4  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
2.1  

Literature

Title: First successful curative use of digoxin-specific Fab antibody fragments in a life-threatening coconut crab (Birgus latro L.) poisoning.

Journal: Toxicon : official journal of the International Society on Toxinology 20121101

Title: Zebrafish chemical screening reveals the impairment of dopaminergic neuronal survival by cardiac glycosides.

Journal: PloS one 20120101

Title: In vitro and in vivo neuroprotective activity of the cardiac glycoside oleandrin from Nerium oleander in brain slice-based stroke models.

Journal: Journal of neurochemistry 20111101

Title: Neriifolin from seeds of Cerbera manghas L. induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells.

Journal: Fitoterapia 20110701

Title: A review of the natural history, toxinology, diagnosis and clinical management of Nerium oleander (common oleander) and Thevetia peruviana (yellow oleander) poisoning.

Journal: Toxicon : official journal of the International Society on Toxinology 20100901

Title: Double lethal coconut crab (Birgus latro L.) poisoning.

Journal: Toxicon : official journal of the International Society on Toxinology 20100101

Title: Cytotoxic effects of cardiac glycosides in colon cancer cells, alone and in combination with standard chemotherapeutic drugs.

Journal: Journal of natural products 20091101

Title: Management of yellow oleander poisoning.

Journal: Clinical toxicology (Philadelphia, Pa.) 20090301

Title: Cutaneous absorption of Oleander: Fact or fiction.

Journal: Journal of emergencies, trauma, and shock 20090101

Title: A screen for drugs that protect against the cytotoxicity of polyglutamine-expanded androgen receptor.

Journal: Human molecular genetics 20040215

Title: Three-dimensional quantitative structure-activity relationship analysis of ligand binding to human sequence antidigoxin monoclonal antibodies using comparative molecular field analysis.

Journal: Journal of medicinal chemistry 20020718

Title: Keller CW, et al. ATG-dependent phagocytosis in dendritic cells drives myelin-specific CD4+ T cell pathogenicity during CNS inflammation. Proc Natl Acad Sci U S A. 2017;114(52):E11228-E11237.

Title: Zhao Q, et al. Neriifolin from seeds of Cerbera manghas L. induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells. Fitoterapia. 2011;82(5):735-741.

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Tags:466-07-9 Molecular Formula|466-07-9 MDL|466-07-9 SMILES|466-07-9 NERIIFOLIN
Catalog No.: AA00D8Q7
466-07-9,MFCD00869436
466-07-9 | NERIIFOLIN
Pack Size: 5mg
Purity: 99%
1 week
$765.00 $535.00
Pack Size: 10mg
Purity: 99%
1 week
$1,193.00 $835.00
Quantity
- +
Add to Card
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bulk Quotation Request
Technical Information
Catalog Number: AA00D8Q7
Chemical Name: NERIIFOLIN
CAS Number: 466-07-9
Molecular Formula: C30H46O8
Molecular Weight: 534.6814
MDL Number: MFCD00869436
SMILES: CO[C@H]1[C@H](O)[C@H](O[C@H]2CC[C@]3([C@@H](C2)CC[C@@H]2[C@@H]3CC[C@]3([C@]2(O)CC[C@@H]3C2=CC(=O)OC2)C)C)O[C@H]([C@@H]1O)C
Properties
Complexity: 968  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 13  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 38  
Hydrogen Bond Acceptor Count: 8  
Hydrogen Bond Donor Count: 3  
Isotope Atom Count: 0  
Rotatable Bond Count: 4  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 2.1  
Literature fold

Title: First successful curative use of digoxin-specific Fab antibody fragments in a life-threatening coconut crab (Birgus latro L.) poisoning.

Journal: Toxicon : official journal of the International Society on Toxinology20121101

Title: Zebrafish chemical screening reveals the impairment of dopaminergic neuronal survival by cardiac glycosides.

Journal: PloS one20120101

Title: In vitro and in vivo neuroprotective activity of the cardiac glycoside oleandrin from Nerium oleander in brain slice-based stroke models.

Journal: Journal of neurochemistry20111101

Title: Neriifolin from seeds of Cerbera manghas L. induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells.

Journal: Fitoterapia20110701

Title: A review of the natural history, toxinology, diagnosis and clinical management of Nerium oleander (common oleander) and Thevetia peruviana (yellow oleander) poisoning.

Journal: Toxicon : official journal of the International Society on Toxinology20100901

Title: Double lethal coconut crab (Birgus latro L.) poisoning.

Journal: Toxicon : official journal of the International Society on Toxinology20100101

Title: Cytotoxic effects of cardiac glycosides in colon cancer cells, alone and in combination with standard chemotherapeutic drugs.

Journal: Journal of natural products20091101

Title: Management of yellow oleander poisoning.

Journal: Clinical toxicology (Philadelphia, Pa.)20090301

Title: Cutaneous absorption of Oleander: Fact or fiction.

Journal: Journal of emergencies, trauma, and shock20090101

Title: A screen for drugs that protect against the cytotoxicity of polyglutamine-expanded androgen receptor.

Journal: Human molecular genetics20040215

Title: Three-dimensional quantitative structure-activity relationship analysis of ligand binding to human sequence antidigoxin monoclonal antibodies using comparative molecular field analysis.

Journal: Journal of medicinal chemistry20020718

Title: Keller CW, et al. ATG-dependent phagocytosis in dendritic cells drives myelin-specific CD4+ T cell pathogenicity during CNS inflammation. Proc Natl Acad Sci U S A. 2017;114(52):E11228-E11237.

Title: Zhao Q, et al. Neriifolin from seeds of Cerbera manghas L. induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells. Fitoterapia. 2011;82(5):735-741.

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