Name: Name:2’-O-Methyl-P-thiouridylyl-(3’→5’)-2’-deoxyadenosine
Brand: AABLOCKS
SKU: AA01E4GM
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA01E4GM

Chemical Name: 2’-O-Methyl-P-thiouridylyl-(3’→5’)-2’-deoxyadenosine

CAS Number: 475650-36-3

Molecular Formula: C20H26N7O10PS

Molecular Weight: 587.5001

MDL Number: MFCD31727872

SMILES: OC[C@H]1O[C@H]([C@@H]([C@@H]1OP(=O)(OC[C@H]1O[C@H](C[C@@H]1O)n1cnc2c1ncnc2N)S)OC)n1ccc(=O)[nH]c1=O

Properties

Complexity: 1010

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 7

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 39

Hydrogen Bond Acceptor Count: 15

Hydrogen Bond Donor Count: 5

Isotope Atom Count: 0

Rotatable Bond Count: 9

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: -1.8

Literature fold

Title: Phosphorothioate di- and trinucleotides as a novel class of anti-hepatitis B virus agents.

Journal: Antimicrobial agents and chemotherapy20040601

Title: Iyer RP, et al. Anti-hepatitis B virus activity of ORI-9020, a novel phosphorothioate dinucleotide, in a transgenic mouse model. Antimicrob Agents Chemother. 2004 Jun;48(6):2318-20.

Title: Danni Colledge, et al. The Novel Antiviral Agent Inarigivir Inhibits Both Nucleos(t)ide Analogue and Capsid Assembly Inhibitor Resistant HBV in vitro.

475650-36-3 | 2’-O-Methyl-P-thiouridylyl-(3’→5’)-2’-deoxyadenosine