Title: Detoxification of benzo[a]pyrene primarily depends on cytochrome P450, while bioactivation involves additional oxidoreductases including 5-lipoxygenase, cyclooxygenase, and aldo-keto reductase in the liver.
Journal: Journal of biochemical and molecular toxicology20170701
Title: Nordihydroguiaretic acid attenuates skin tumorigenesis in Swiss albino mice with the condition of topical co-administration of an immunosuppressant.
Journal: Chemico-biological interactions20150525
Title: Human sex hormone-binding globulin binding affinities of 125 structurally diverse chemicals and comparison with their binding to androgen receptor, estrogen receptor, and α-fetoprotein.
Journal: Toxicological sciences : an official journal of the Society of Toxicology20150201
Title: Restraining the flexibility of the central linker in terameprocol results in constrained analogs with improved growth inhibitory activity.
Journal: Bioorganic & medicinal chemistry letters20131115
Title: Small molecule activators of the Nrf2-HO-1 antioxidant axis modulate heme metabolism and inflammation in BV2 microglia cells.
Journal: Pharmacological research20131001
Title: Rat α-Fetoprotein binding affinities of a large set of structurally diverse chemicals elucidated the relationships between structures and binding affinities.
Journal: Chemical research in toxicology20121119
Title: mTORC1 is a target of nordihydroguaiaretic acid to prevent breast tumor growth in vitro and in vivo.
Journal: Breast cancer research and treatment20121101
Title: Arachidonic acid stimulates DNA synthesis in brown preadipocytes through the activation of protein kinase C and MAPK.
Journal: Biochimica et biophysica acta20121001
Title: Synthesis and SAR studies of 3-allyl-4-prenyloxyaniline amides as potent 15-lipoxygenase inhibitors.
Journal: Bioorganic & medicinal chemistry20120915
Title: Phenolic compound production in relation to differentiation in cell and tissue cultures of Larrea divaricata (Cav.).
Journal: Plant science : an international journal of experimental plant biology20120901
Title: Synthesis of sulfur containing dihydro-pyrrolo derivatives and their biological evaluation as antioxidants.
Journal: Bioorganic & medicinal chemistry20120901
Title: Natural polyphenols as modulators of TTR amyloidogenesis: in vitro and in vivo evidences towards therapy.
Journal: Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis20120601
Title: Subepithelial trypsin induces enteric nerve-mediated anion secretion by activating proteinase-activated receptor 1 in the mouse cecum.
Journal: The journal of physiological sciences : JPS20120501
Title: Novel NSAID 1-acyl-4-cycloalkyl/arylsemicarbazides and 1-acyl-5-benzyloxy/hydroxy carbamoylcarbazides as potential anticancer agents and antioxidants.
Journal: European journal of medicinal chemistry20120501
Title: Phase I study of terameprocol in patients with recurrent high-grade glioma.
Journal: Neuro-oncology20120401
Title: Dihydroceramide accumulation and reactive oxygen species are distinct and nonessential events in 4-HPR-mediated leukemia cell death.
Journal: Biochemistry and cell biology = Biochimie et biologie cellulaire20120401
Title: The protective effect of nordihydroguaiaretic acid on cerebral ischemia/reperfusion injury is mediated by the JNK pathway.
Journal: Brain research20120322
Title: The dietary supplementation of nordihydroguaiaretic acid (NDGA) delayed the loss of climbing ability in Drosophila model of Parkinson's disease.
Journal: Journal of dietary supplements20120301
Title: Signaling pathways activated by the phytochemical nordihydroguaiaretic acid contribute to a Keap1-independent regulation of Nrf2 stability: Role of glycogen synthase kinase-3.
Journal: Free radical biology & medicine20120115
Title: Α-aryl-N-alkyl nitrones, as potential agents for stroke treatment: synthesis, theoretical calculations, antioxidant, anti-inflammatory, neuroprotective, and brain-blood barrier permeability properties.
Journal: Journal of medicinal chemistry20120112
Title: A phase II study of insulin-like growth factor receptor inhibition with nordihydroguaiaretic acid in men with non-metastatic hormone-sensitive prostate cancer.
Journal: Oncology reports20120101
Title: Hypoxia promotes rabbit pulmonary artery smooth muscle cells proliferation through a 15-LOX-2 product 15(S)-hydroxyeicosatetraenoic acid.
Journal: Prostaglandins, leukotrienes, and essential fatty acids20120101
Title: Fragment-based design, docking, synthesis, biological evaluation and structure-activity relationships of 2-benzo/benzisothiazolimino-5-aryliden-4-thiazolidinones as cycloxygenase/lipoxygenase inhibitors.
Journal: European journal of medicinal chemistry20120101
Title: Interleukin-1 induction of aggrecanase gene expression in human articular chondrocytes is mediated by mitogen-activated protein kinases.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology20120101
Title: Jasmonic acid is involved in the signaling pathway for fungal endophyte-induced volatile oil accumulation of Atractylodes lancea plantlets.
Journal: BMC plant biology20120101
Title: Arachidonic acid and its COX1/2 metabolites inhibit interferon-γ mediated induction of indoleamine-2,3 dioxygenase in THP-1 cells and human monocytes.
Journal: Prostaglandins, leukotrienes, and essential fatty acids20120101
Title: Evaluation of the antioxidative properties of lipoxygenase inhibitors.
Journal: Pharmacological reports : PR20120101
Title: cPLA(2)α gene activation by IL-1β is dependent on an upstream kinase pathway, enzymatic activation and downstream 15-lipoxygenase activity: a positive feedback loop.
Journal: Cellular signalling20111201
Title: Effects of hypolipidemic agent nordihydroguaiaretic acid on lipid droplets and hepatitis C virus.
Journal: Hepatology (Baltimore, Md.)20111201
Title: Synthesis and biological evaluation of (2,5-dihydro-1H-pyrrol-1-yl)-2H-chromen-2-ones as free radical scavengers.
Journal: European journal of medicinal chemistry20111201
Title: Alteration in inflammatory/apoptotic pathway and histone modifications by nordihydroguaiaretic acid prevents acute pancreatitis in swiss albino mice.
Journal: Apoptosis : an international journal on programmed cell death20111101
Title: Design, synthesis and biological evaluation of benzo[1.3.2]dithiazolium ylide 1,1-dioxide derivatives as potential dual cyclooxygenase-2/5-lipoxygenase inhibitors.
Journal: Bioorganic & medicinal chemistry20111101
Title: Bioassay-guided identification of an anti-inflammatory prenylated acylphloroglucinol from Melicope ptelefolia and molecular insights into its interaction with 5-lipoxygenase.
Journal: Bioorganic & medicinal chemistry20111101
Title: Significant biological role of sp1 transactivation in multiple myeloma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research20111015
Title: Tumor-associated macrophages mediate immunosuppression in the renal cancer microenvironment by activating the 15-lipoxygenase-2 pathway.
Journal: Cancer research20111015
Title: Effects of transient receptor potential channel blockers on pacemaker activity in interstitial cells of Cajal from mouse small intestine.
Journal: Molecules and cells20110831
Title: The lipogenesis pathway as a cancer target.
Journal: Journal of medicinal chemistry20110825
Title: Thrombin inhibitors with lipid peroxidation and lipoxygenase inhibitory activities.
Journal: Bioorganic & medicinal chemistry letters20110815
Title: Discovery of potent and selective inhibitors of human platelet-type 12- lipoxygenase.
Journal: Journal of medicinal chemistry20110811
Title: Development of Neh2-luciferase reporter and its application for high throughput screening and real-time monitoring of Nrf2 activators.
Journal: Chemistry & biology20110624
Title: An inhibitor of arachidonate 5-lipoxygenase, Nordy, induces differentiation and inhibits self-renewal of glioma stem-like cells.
Journal: Stem cell reviews20110601
Title: Synthesis, in silico docking experiments of new 2-pyrrolidinone derivatives and study of their anti-inflammatory activity.
Journal: Bioorganic & medicinal chemistry20110501
Title: Melittin activates TRPV1 receptors in primary nociceptive sensory neurons via the phospholipase A2 cascade pathways.
Journal: Biochemical and biophysical research communications20110429
Title: Modulation of lipid peroxidation and mitochondrial function improves neuropathology in Huntington's disease mice.
Journal: Acta neuropathologica20110401
Title: ABA controls H₂O₂ accumulation through the induction of OsCATB in rice leaves under water stress.
Journal: Plant & cell physiology20110401
Title: Discovery of a small molecule PDI inhibitor that inhibits reduction of HIV-1 envelope glycoprotein gp120.
Journal: ACS chemical biology20110318
Title: Involvement of H-Ras and reactive oxygen species in proinflammatory cytokine-induced matrix metalloproteinase-13 expression in human articular chondrocytes.
Journal: Archives of biochemistry and biophysics20110315
Title: Role of arachidonic acid lipoxygenase metabolites in acetylcholine-induced relaxations of mouse arteries.
Journal: American journal of physiology. Heart and circulatory physiology20110301
Title: Activated oncogenic pathways and therapeutic targets in extranodal nasal-type NK/T cell lymphoma revealed by gene expression profiling.
Journal: The Journal of pathology20110301
Title: Removal of the toxic effects of chlormadinon acetate on the development of Drosophila melanogaster via the use of nordihydroguaiaretic acid.
Journal: Toxicology and industrial health20110201
Title: Localization of lipoxygenase activity on the oil bodies and in protoplasts using a novel fluorescence imaging method.
Journal: Plant physiology and biochemistry : PPB20110201
Title: Topical anti-inflammatory activity of boropinic acid and its natural and semi-synthetic derivatives.
Journal: Bioorganic & medicinal chemistry letters20110115
Title: The complement component C5a is present in human coronary lesions in vivo and induces the expression of MMP-1 and MMP-9 in human macrophages in vitro.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology20110101
Title: Adrenocorticotrophic hormone-stimulated cortisol release by the head kidney inter-renal tissue from sea bream (Sparus aurata) fed with linseed oil and soyabean oil.
Journal: The British journal of nutrition20110101
Title: Analysis of nordihydroguaiaretic acid in Larrea divaricata Cav. extracts by micellar electrokinetic chromatography.
Journal: Phytochemical analysis : PCA20110101
Title: Design, synthesis and pharmacobiological evaluation of novel acrylic acid derivatives acting as lipoxygenase and cyclooxygenase-1 inhibitors with antioxidant and anti-inflammatory activities.
Journal: European journal of medicinal chemistry20110101
Title: Terameprocol (tetra-O-methyl nordihydroguaiaretic acid), an inhibitor of Sp1-mediated survivin transcription, induces radiosensitization in non-small cell lung carcinoma.
Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer20110101
Title: Glycosylated nordihydroguaiaretic acids as anti-cancer agents.
Journal: Bioorganic & medicinal chemistry letters20110101
Title: One-pot microwave assisted synthesis under green chemistry conditions, antioxidant screening, and cytotoxicity assessments of benzimidazole Schiff bases and pyrimido[1,2-a]benzimidazol-3(4H)-ones.
Journal: European journal of medicinal chemistry20110101
Title: Inhibitory effect of nordihydroguaiaretic acid on β-catenin/Tcf signalling in β-catenin-activated cells.
Journal: Cell biochemistry and function20110101
Title: Dynein/Dynactin-mediated transport of kinetochore components off kinetochores and onto spindle poles induced by nordihydroguaiaretic acid.
Journal: PloS one20110101
Title: Nordihydroguaiaretic acid (NDGA) inhibits ritonavir-induced endothelial dysfunction in porcine pulmonary arteries.
Journal: Medical science monitor : international medical journal of experimental and clinical research20110101
Title: Anti-inflammatory and redox-protective activities of citronellal.
Journal: Biological research20110101
Title: Life extension by diet restriction and N-acetyl-L-cysteine in genetically heterogeneous mice.
Journal: The journals of gerontology. Series A, Biological sciences and medical sciences20101201
Title: Convenient synthesis and biological profile of 5-amino-substituted 1,2,4-oxadiazole derivatives.
Journal: European journal of medicinal chemistry20101201
Title: Inhibition of poxvirus growth by Terameprocol, a methylated derivative of nordihydroguaiaretic acid.
Journal: Antiviral research20101201
Title: Does conjugation of antioxidants improve their antioxidative/anti-inflammatory potential?
Journal: Bioorganic & medicinal chemistry20101201
Title: Role of leukotriene B4 in celecoxib-mediated anticancer effect.
Journal: Biochemical and biophysical research communications20101112
Title: Hepatoma-derived growth factor promotes the resistance to anti-tumor effects of nordihydroguaiaretic acid in colorectal cancer cells.
Journal: European journal of pharmacology20101025
Title: Nordihydroguaiaretic acid protects against high-fat diet-induced fatty liver by activating AMP-activated protein kinase in obese mice.
Journal: Biochemical and biophysical research communications20101008
Title: Synthesis and biological evaluation of indomethacin analogs possessing a N-difluoromethyl-1,2-dihydropyrid-2-one ring system: a search for novel cyclooxygenase and lipoxygenase inhibitors.
Journal: Bioorganic & medicinal chemistry letters20101001
Title: In vitro growth-inhibitory effect of plant-derived extracts and compounds against Paenibacillus larvae and their acute oral toxicity to adult honey bees.
Journal: Veterinary microbiology20100928
Title: Design, synthesis, and biological evaluation of prenylated chalcones as 5-LOX inhibitors.
Journal: Bioorganic & medicinal chemistry20100815
Title: Structure-activity relationship studies of acridones as potential antipsoriatic agents. 1. Synthesis and antiproliferative activity of simple N-unsubstituted 10H-acridin-9-ones against human keratinocyte growth.
Journal: European journal of medicinal chemistry20100801
Title: Synthesis and biological screening of some novel amidocarbamate derivatives of ketoprofen.
Journal: European journal of medicinal chemistry20100701
Title: A novel synthesis of 3-aryl coumarins and evaluation of their antioxidant and lipoxygenase inhibitory activity.
Journal: Bioorganic & medicinal chemistry letters20100701
Title: Mechanism of the OH radical scavenging activity of nordihydroguaiaretic acid: a combined theoretical and experimental study.
Journal: The journal of physical chemistry. B20100520
Title: Characterization and modulation of canine mast cell derived eicosanoids.
Journal: Veterinary immunology and immunopathology20100515
Title: Pharmacophore modeling strategies for the development of novel nonsteroidal inhibitors of human aromatase (CYP19).
Journal: Bioorganic & medicinal chemistry letters20100515
Title: Molecular mechanisms and clinical applications of nordihydroguaiaretic acid (NDGA) and its derivatives: an update.
Journal: Medical science monitor : international medical journal of experimental and clinical research20100428
Title: [Nordihydroguaiaretic acid partially inhibits inflammatory responses after focal cerebral ischemia in rats].
Journal: Sheng li xue bao : [Acta physiologica Sinica]20100425
Title: [Elucidation of mechanism underlying amyloid-beta peptide aggregation and its neurotoxicity expression and inhibition of these molecular processes by beneficial synthetic and natural compounds with low-molecular weights-new approaches to fundamental treatment and prevention of Alzheimer's disease].
Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan20100401
Title: [Ganglioside cluster-mediated aggregation and cytotoxicity of amyloid beta-peptide: molecular mechanism and inhibition].
Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan20100401
Title: In vitro immunomodulatory effects of fractions obtained from aqueous extracts of Larrea divaricata Cav (Jarilla) on mouse peritoneal macrophages.
Journal: Immunopharmacology and immunotoxicology20100301
Title: Rescue of ER oxidoreductase function through polyphenolic phytochemical intervention: implications for subcellular traffic and neurodegenerative disorders.
Journal: Biochemical and biophysical research communications20100219
Title: A novel porous collagen scaffold around an implantable biosensor for improving biocompatibility. II. Long-term in vitro/in vivo sensitivity characteristics of sensors with NDGA- or GA-crosslinked collagen scaffolds.
Journal: Journal of biomedical materials research. Part A20100201
Title: Crosslinking effect of Nordihydroguaiaretic acid (NDGA) on decellularized heart valve scaffold for tissue engineering.
Journal: Journal of materials science. Materials in medicine20100201
Title: The direct effect of levobupivacaine in isolated rat aorta involves lipoxygenase pathway activation and endothelial nitric oxide release.
Journal: Anesthesia and analgesia20100201
Title: Phenylacetic acid regioisomers possessing a N-difluoromethyl-1,2-dihydropyrid-2-one pharmacophore: evaluation as dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity.
Journal: Bioorganic & medicinal chemistry letters20100201
Title: ROCK pathway participates in the processes that 15-hydroxyeicosatetraenoic acid (15-HETE) mediated the pulmonary vascular remodeling induced by hypoxia in rat.
Journal: Journal of cellular physiology20100101
Title: Syntheses and evaluation of the antioxidant activity of acitretin analogs with amide bond(s) in the polyene spacer.
Journal: European journal of medicinal chemistry20100101
Title: Inhibitory activity of Brazilian green propolis components and their derivatives on the release of cys-leukotrienes.
Journal: Bioorganic & medicinal chemistry20100101
Title: Oxidative stress in NSC-741909-induced apoptosis of cancer cells.
Journal: Journal of translational medicine20100101
Title: Metabolic engineering of resveratrol and other longevity boosting compounds.
Journal: BioFactors (Oxford, England)20100101
Title: Synthesis and anti-inflammatory evaluation of novel angularly or linearly fused coumarins.
Journal: European journal of medicinal chemistry20091201
Title: A cell-based assay for screening lipoxygenase inhibitors.
Journal: Prostaglandins & other lipid mediators20091201
Title: Natural and synthetic 2'-hydroxy-chalcones and aurones: synthesis, characterization and evaluation of the antioxidant and soybean lipoxygenase inhibitory activity.
Journal: Bioorganic & medicinal chemistry20091201
Title: Phenolic compounds prevent Alzheimer's pathology through different effects on the amyloid-beta aggregation pathway.
Journal: The American journal of pathology20091201
Title: Assembly of an intact Golgi complex requires phospholipase A2 (PLA2) activity, membrane tubules, and dynein-mediated microtubule transport.
Journal: Biochemical and biophysical research communications20091120
Title: Synthesis of modified homo-N-nucleosides from the reactions of mesityl nitrile oxide with 9-allylpurines and their influence on lipid peroxidation and thrombin inhibition.
Journal: Bioorganic & medicinal chemistry letters20091115
Title: CYP-omega-hydroxylation-dependent metabolites of arachidonic acid inhibit the basolateral 10 pS chloride channel in the rat thick ascending limb.
Journal: Kidney international20091001
Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Journal: Nature chemical biology20091001
Title: Using enzyme assays to evaluate the structure and bioactivity of sponge-derived meroterpenes.
Journal: Journal of natural products20091001
Title: A chemical screening approach reveals that indole fluorescence is quenched by pre-fibrillar but not fibrillar amyloid-beta.
Journal: Bioorganic & medicinal chemistry letters20090901
Title: Nordihydroguaiaretic acid inhibits transforming growth factor beta type 1 receptor activity and downstream signaling.
Journal: European journal of pharmacology20090815
Title: Synthesis, characterization, and anti-melanoma activity of tetra-O-substituted analogs of nordihydroguaiaretic acid.
Journal: Bioorganic & medicinal chemistry letters20090815
Title: Cannabidiol-2',6'-dimethyl ether, a cannabidiol derivative, is a highly potent and selective 15-lipoxygenase inhibitor.
Journal: Drug metabolism and disposition: the biological fate of chemicals20090801
Title: Urea and carbamate derivatives of primaquine: synthesis, cytostatic and antioxidant activities.
Journal: Bioorganic & medicinal chemistry20090801
Title: Reactive oxygen species and lipoxygenases regulate the oncogenicity of NPM-ALK-positive anaplastic large cell lymphomas.
Journal: Oncogene20090723
Title: Synthesis and evaluation of the antioxidant and anti-inflammatory activity of novel coumarin-3-aminoamides and their alpha-lipoic acid adducts.
Journal: European journal of medicinal chemistry20090701
Title: Jasmonic acid is induced in a biphasic manner in response of pea seedlings to wounding.
Journal: Journal of integrative plant biology20090601
Title: Rethinking a drug treatment failure on a traditional ALS target.
Journal: Experimental neurology20090401
Title: 5-Lipoxygenase plays a role in the control of parasite burden and contributes to oxidative damage of erythrocytes in murine Chagas' disease.
Journal: Immunology letters20090324
Title: Glucose-induced delay of seed germination in rice is mediated by the suppression of ABA catabolism rather than an enhancement of ABA biosynthesis.
Journal: Plant & cell physiology20090301
Title: Synthesis of hydroxycoumarins and hydroxybenzo[f]- or [h]coumarins as lipid peroxidation inhibitors.
Journal: Bioorganic & medicinal chemistry letters20090215
Title: Hypoxia suppresses KV1.5 channel expression through endogenous 15-HETE in rat pulmonary artery.
Journal: Prostaglandins & other lipid mediators20090101
Title: Identification of xenoestrogens in food additives by an integrated in silico and in vitro approach.
Journal: Chemical research in toxicology20090101
Title: Inhibition of ovulation by a lipoxygenase inhibitor involves reduced cyclooxygenase-2 expression and prostaglandin E2 production in gonadotropin-primed immature rats.
Journal: Reproduction (Cambridge, England)20090101
Title: Post-treatment effects of erythropoietin and nordihydroguaiaretic acid on recovery from cisplatin-induced acute renal failure in the rat.
Journal: Journal of Korean medical science20090101
Title: Effects of celecoxib and nordihydroguaiaretic acid on puromycin aminonucleoside-induced nephrosis in the rat.
Journal: Journal of Korean medical science20090101
Title: The effect of nordihydroguaiaretic acid on iodoacetate-induced toxicity in cultured neurons.
Journal: Journal of biochemical and molecular toxicology20090101
Title: Substance P upregulates LTB4 in rat adherent macrophages from granuloma induced by KMnO4.
Journal: Neurotoxicity research20090101
Title: Nordihydroguaiaretic acid analogues: their chemical synthesis and biological activities.
Journal: Current topics in medicinal chemistry20090101
Title: Chemosensitizing effect of nordihydroguaiaretic acid and its tetra-acetylated derivative on parental and multiresistant TA3 mouse mammary adenocarcinoma cells.
Journal: In vivo (Athens, Greece)20090101
Title: Characterization of novel furan compounds on the basis of their radical scavenging activity and cytoprotective effects against glutamate- and lipopolysaccharide-induced insults.
Journal: Bioorganic & medicinal chemistry20081215
Title: Cinnamyl-3,4-dihydroxy-alpha-cyanocinnamate and nordihydroguaiaretic acid inhibit human Kv1.5 currents independently of lipoxygenase.
Journal: European journal of pharmacology20081214
Title: Nordihydroguaiaretic acid activates the antioxidant pathway Nrf2/HO-1 and protects cerebellar granule neurons against oxidative stress.
Journal: Neuroscience letters20081212
Title: Ethylene and ABA interactions in the regulation of flower induction in Pharbitis nil.
Journal: Journal of plant physiology20081201
Title: Abscisic acid is involved in chitosan-induced resistance to tobacco necrosis virus (TNV).
Journal: Plant physiology and biochemistry : PPB20081201
Title: Overexpression of 5-lipoxygenase in colon polyps and cancer and the effect of 5-LOX inhibitors in vitro and in a murine model.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research20081015
Title: A novel porous collagen scaffold around an implantable biosensor for improving biocompatibility. I. In vitro/in vivo stability of the scaffold and in vitro sensitivity of the glucose sensor with scaffold.
Journal: Journal of biomedical materials research. Part A20081001
Title: Nordihydroguaiaretic acid and aspirin increase lifespan of genetically heterogeneous male mice.
Journal: Aging cell20081001
Title: Conjugated linoleic acid-induced fat loss dependence on Delta6-desaturase or cyclooxygenase.
Journal: Obesity (Silver Spring, Md.)20081001
Title: Nordihydroguaiaretic acid inhibits an activated fibroblast growth factor receptor 3 mutant and blocks downstream signaling in multiple myeloma cells.
Journal: Cancer research20080915
Title: Nordihydroguaiaretic acid increases glutamate uptake in vitro and in vivo: therapeutic implications for amyotrophic lateral sclerosis.
Journal: Experimental neurology20080901
Title: Nordihydroguaiaretic acid autoxidation produces a schisandrin-like dibenzocyclooctadiene lignan.
Journal: Journal of natural products20080901
Title: The non-steroidal anti-inflammatory drugs protect mouse cochlea against acoustic injury.
Journal: The Tohoku journal of experimental medicine20080901
Title: Regulation of pro-inflammatory responses by lipoxygenases via intracellular reactive oxygen species in vitro and in vivo.
Journal: Experimental & molecular medicine20080831
Title: Inhibitory effects of nordihydroguaiaretic acid (NDGA) on the IGF-1 receptor and androgen dependent growth of LAPC-4 prostate cancer cells.
Journal: The Prostate20080801
Title: The differentiation-inducing effect of Nordy on HPV-16 subgenes-immortalized human endocervical cells H8.
Journal: Anti-cancer drugs20080801
Title: Synthesis and biological evaluation of 1-(benzenesulfonamido)-2-[5-(N-hydroxypyridin-2(1H)-one)]acetylene regioisomers: a novel class of 5-lipoxygenase inhibitors.
Journal: Bioorganic & medicinal chemistry letters20080715
Title: Sevoflurane and the feto-placental vasculature: the role of nitric oxide and vasoactive eicosanoids.
Journal: Anesthesia and analgesia20080701
Title: Nordihydroguaiaretic acid, a cytotoxic insulin-like growth factor-I receptor/HER2 inhibitor in trastuzumab-resistant breast cancer.
Journal: Molecular cancer therapeutics20080701
Title: Nordihydroguaiaretic acid restores expression of silenced E-cadherin gene in human breast cancer cell lines and xenografts.
Journal: Anti-cancer drugs20080601
Title: Phase I clinical trial of repeat dose terameprocol vaginal ointment in healthy female volunteers.
Journal: Sexually transmitted diseases20080601
Title: [Advances in the research of lipoxygenase inhibitors].
Journal: Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences20080601
Title: Future target molecules for influenza treatment.
Journal: Mini reviews in medicinal chemistry20080501
Title: Screening of 397 chemicals and development of a quantitative structure--activity relationship model for androgen receptor antagonism.
Journal: Chemical research in toxicology20080401
Title: New nordihydroguaiaretic acid derivatives as anti-HIV agents.
Journal: Bioorganic & medicinal chemistry letters20080315
Title: Effect of the interaction between lipoxygenase pathway and progesterone on the regulation of hydroxysteroid 11-Beta dehydrogenase 2 in cultured human term placental trophoblasts.
Journal: Biology of reproduction20080301
Title: Nordihydroguaiaretic acid attenuates potassium dichromate-induced oxidative stress and nephrotoxicity.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association20080301
Title: Terameprocol, a novel site-specific transcription inhibitor with anticancer activity.
Journal: IDrugs : the investigational drugs journal20080301
Title: Nordihydroguaiaretic acid (NDGA), an inhibitor of the HER2 and IGF-1 receptor tyrosine kinases, blocks the growth of HER2-overexpressing human breast cancer cells.
Journal: Journal of cellular biochemistry20080201
Title: Cytosolic phospholipase A2 and arachidonic acid metabolites modulate ventilator-induced permeability increases in isolated mouse lungs.
Journal: Journal of applied physiology (Bethesda, Md. : 1985)20080201
Title: Unique proteomic features induced by a potential antiglioma agent, Nordy (dl-nordihydroguaiaretic acid), in glioma cells.
Journal: Proteomics20080201
Title: A pilot dose-escalation study of the effects of nordihydroguareacetic acid on hormone and prostate specific antigen levels in patients with relapsed prostate cancer.
Journal: BJU international20080201
Title: [Effect of nordy on the function of endothelial progenitor cells from human umbilical cord blood induced by vascular endothelial growth factor].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica20080201
Title: Reactivation of methylation-silenced tumor suppressor gene p16INK4a by nordihydroguaiaretic acid and its implication in G1 cell cycle arrest.
Journal: Life sciences20080130
Title: The flavonoid quercetin regulates growth and gene expression in rat FRTL-5 thyroid cells.
Journal: Endocrinology20080101
Title: RANTES (CCL5) potentiates calcium ionophore in the production of LTB4 in rat adherent macrophages from granuloma induced by KMnO4: inhibiton by NDGA.
Journal: Pharmacological research20080101
Title: Antigenotoxic effect of nordihydroguaiaretic acid against chlormadinone acetate-induced genotoxicity in mice bone-marrow cells.
Journal: Journal of natural medicines20080101
Title: Organic extracts of Larrea divaricata Cav. induced apoptosis on tumoral MCF7 cells with an higher cytotoxicity than nordihydroguaiaretic acid or paclitaxel.
Journal: Journal of experimental therapeutics & oncology20080101
Title: Single-laboratory validated method for determination of nordihydroguaiaretic acid in chaparral-containing dietary supplements.
Journal: Journal of AOAC International20080101
Title: Inhibitory effect of nordihydroguaiaretic acid and its tetra-acetylated derivative on respiration and growth of adenocarcinoma TA3 and its multiresistant variant TA3MTX-R.
Journal: In vivo (Athens, Greece)20080101
Title: Nordihydroguaiaretic acid inhibits insulin-like growth factor signaling, growth, and survival in human neuroblastoma cells.
Journal: Journal of cellular biochemistry20071215
Title: Structure-activity relationship studies of flavonoids as potent inhibitors of human platelet 12-hLO, reticulocyte 15-hLO-1, and prostate epithelial 15-hLO-2.
Journal: Bioorganic & medicinal chemistry20071201
Title: Copper-induced peroxidation of phosphatidylserine-containing liposomes is inhibited by nanomolar concentrations of specific antioxidants.
Journal: Chemistry and physics of lipids20071201
Title: Phase I/II clinical safety studies of terameprocol vaginal ointment.
Journal: Gynecologic oncology20071201
Title: Nordihydroguaiaretic acid increases endothelial nitric oxide synthase expression via the transcription factor AP-1.
Journal: DNA and cell biology20071201
Title: Synthesis and anti-inflammatory/antioxidant activities of some new ring substituted 3-phenyl-1-(1,4-di-N-oxide quinoxalin-2-yl)-2-propen-1-one derivatives and of their 4,5-dihydro-(1H)-pyrazole analogues.
Journal: Bioorganic & medicinal chemistry letters20071201
Title: Nordihydroguaiaretic acid induces astroglial death via glutathione depletion.
Journal: Journal of neuroscience research20071101
Title: Inhibition of L-type Ca2+ channel current and negative inotropy induced by arachidonic acid in adult rat ventricular myocytes.
Journal: American journal of physiology. Cell physiology20071101
Title: Inhibitory effect of nordihydroguaiaretic acid, a plant lignan, on Helicobacter pylori-associated gastric carcinogenesis in Mongolian gerbils.
Journal: Cancer science20071101
Title: Penta-acetyl geniposide-induced apoptosis involving transcription of NGF/p75 via MAPK-mediated AP-1 activation in C6 glioma cells.
Journal: Toxicology20070905
Title: A novel lipoxygenase inhibitor Nordy attenuates malignant human glioma cell responses to chemotactic and growth stimulating factors.
Journal: Journal of neuro-oncology20070901
Title: Synthesis and pharmacochemical evaluation of novel aryl-acetic acid inhibitors of lipoxygenase, antioxidants, and anti-inflammatory agents.
Journal: Bioorganic & medicinal chemistry20070901
Title: Lipoxygenase inhibitors induce death receptor 5/TRAIL-R2 expression and sensitize malignant tumor cells to TRAIL-induced apoptosis.
Journal: Cancer science20070901
Title: The anticancer activity of the transcription inhibitor terameprocol (meso-tetra-O-methyl nordihydroguaiaretic acid) formulated for systemic administration.
Journal: Anti-cancer drugs20070901
Title: Oxidation of the lignan nordihydroguaiaretic acid.
Journal: Chemical research in toxicology20070901
Title: [Effect of nordy on biological behaviors of malignant glioma cell line U87MG and the analysis of differential expression proteome].
Journal: Zhonghua bing li xue za zhi = Chinese journal of pathology20070901
Title: Correlation of Golgi localization of ZW10 and centrosomal accumulation of dynactin.
Journal: Biochemical and biophysical research communications20070803
Title: The anti-cancer compound Nordy inhibits CXCR4-mediated production of IL-8 and VEGF by malignant human glioma cells.
Journal: Journal of neuro-oncology20070801
Title: An Aging Interventions Testing Program: study design and interim report.
Journal: Aging cell20070801
Title: Inhibition of IGF-1R and lipoxygenase by nordihydroguaiaretic acid (NDGA) analogs.
Journal: Bioorganic & medicinal chemistry letters20070715
Title: Modification of sericin-free silk fibers for ligament tissue engineering application.
Journal: Journal of biomedical materials research. Part B, Applied biomaterials20070701
Title: A plant lignan, 3'-O-methyl-nordihydroguaiaretic acid, suppresses papillomavirus E6 protein function, stabilizes p53 protein, and induces apoptosis in cervical tumor cells.
Journal: Molecular carcinogenesis20070701
Title: Design and synthesis of novel quinolinone-3-aminoamides and their alpha-lipoic acid adducts as antioxidant and anti-inflammatory agents.
Journal: Journal of medicinal chemistry20070517
Title: Lipoxygenase inhibitory constituents of the fruits of noni (Morinda citrifolia) collected in Tahiti.
Journal: Journal of natural products20070501
Title: Regulation of topoisomerase II alpha and beta in HIV-1 infected and uninfected neuroblastoma and astrocytoma cells: involvement of distinct nordihydroguaretic acid sensitive inflammatory pathways.
Journal: Archives of biochemistry and biophysics20070501
Title: Endogenous production of reactive oxygen species is required for stimulation of human articular chondrocyte matrix metalloproteinase production by fibronectin fragments.
Journal: Free radical biology & medicine20070501
Title: Effect of heating on peroxynitrite scavenging capacity of garlic.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association20070401
Title: Tetra-O-methyl nordihydroguaiaretic acid inhibits growth and induces death of leukemia cells independent of Cdc2 and survivin.
Journal: Leukemia & lymphoma20070401
Title: Protective role of nordihydroguaiaretic acid (NDGA) against the genotoxic damage induced by ethynodiol diacetate in human lymphocytes in vitro.
Journal: Journal of environmental biology20070401
Title: Assessing 12(S)-lipoxygenase inhibitory activity using colorectal cancer cells overexpressing the enzyme.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association20070301
Title: [Effect of nordy on FPR function of malignant human glioma cell line U87].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica20070301
Title: [Nordy inhibits cell proliferation and angiogenic factor production of malignant human glioma cells mediated by formylpeptide receptor].
Journal: Zhonghua yi xue za zhi20070213
Title: Nordihydroguaiaretic acid affects multiple dynein-dynactin functions in interphase and mitotic cells.
Journal: Molecular pharmacology20070201
Title: 5-LOX inhibitor modulates the inflammatory responses provoked by Helicobacter pylori infection.
Journal: Helicobacter20070201
Title: Effects of arachidonate metabolism inhibitors on basal and human chorionic gonadotropin-stimulated progesterone secretion by rat corpus luteum cells in vitro.
Journal: Prostaglandins & other lipid mediators20070201
Title: Design and study of some novel ibuprofen derivatives with potential nootropic and neuroprotective properties.
Journal: Bioorganic & medicinal chemistry20070115
Title: Exploiting hypoxia in solid tumors to achieve oncolysis.
Journal: Medical hypotheses20070101
Title: Transport characteristics of a novel local drug delivery system using nordihydroguaiaretic acid (NDGA)-polymerized collagen fibers.
Journal: Biotechnology progress20070101
Title: Effect of hydroalcoholic extract of Zingiber officinalis rhizomes on LPS-induced rat airway hyperreactivity and lung inflammation.
Journal: Prostaglandins, leukotrienes, and essential fatty acids20070101
Title: Effects of inhibitors of the arachidonic acid cascade on primary muscle culture from a Duchenne muscular dystrophy patient.
Journal: Prostaglandins, leukotrienes, and essential fatty acids20070101
Title: Early effects triggered by Larrea divaricata Cav. on murine macrophages at apoptotic concentrations.
Journal: Immunopharmacology and immunotoxicology20070101
Title: Activation and apoptosis of mouse peritoneal macrophages by extracts of Larrea divaricata Cav. (jarilla).
Journal: International immunopharmacology20061220
Title: Enhancing engraftment of neonatal porcine xenoislet with CTLA4Ig and nordihydroguaiaretic acid.
Journal: Transplantation proceedings20061201
Title: Reversal of multidrug resistance by two nordihydroguaiaretic acid derivatives, M4N and maltose-M3N, and their use in combination with doxorubicin or paclitaxel.
Journal: Cancer chemotherapy and pharmacology20061101
Title: Neurotoxicity of lidocaine involves specific activation of the p38 mitogen-activated protein kinase, but not extracellular signal-regulated or c-jun N-terminal kinases, and is mediated by arachidonic acid metabolites.
Journal: Anesthesiology20061101
Title: Prooxidant activity and toxicity of nordihydroguaiaretic acid in clone-9 rat hepatocyte cultures.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association20061001
Title: 5-Hydroxyeicosatetraenoic acid is a key intermediate of the arachidonate-dependent protective signaling in monocytes/macrophages exposed to peroxynitrite.
Journal: Journal of leukocyte biology20061001
Title: Effects of selective inhibition of cyclooxygenase and lipooxygenase pathways in follicle rupture and ovulation in the rat.
Journal: Reproduction (Cambridge, England)20061001
Title: Effects of hyposmotic stress on exocytosis in isolated turbot, Scophthalmus maximus, hepatocytes.
Journal: Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology20060901
Title: Oxidative stress-driven mechanisms of nordihydroguaiaretic acid-induced apoptosis in FL5.12 cells.
Journal: Toxicology and applied pharmacology20060801
Title: Survivin-dependent and -independent pathways and the induction of cancer cell death by tetra-O-methyl nordihydroguaiaretic acid.
Journal: Seminars in oncology20060801
Title: Single-cell enzyme concentrations, kinetics, and inhibition analysis using high-density hydrodynamic cell isolation arrays.
Journal: Analytical chemistry20060715
Title: Mechanisms regulating tumor angiogenesis by 12-lipoxygenase in prostate cancer cells.
Journal: The Journal of biological chemistry20060707
Title: The action of extracellular NAD+ on gluconeogenesis in the perfused rat liver.
Journal: Molecular and cellular biochemistry20060601
Title: Nordihydroguaiaretic acid is a potent in vitro scavenger of peroxynitrite, singlet oxygen, hydroxyl radical, superoxide anion and hypochlorous acid and prevents in vivo ozone-induced tyrosine nitration in lungs.
Journal: Free radical research20060501
Title: Nordy, a synthetic lipoxygenase inhibitor, inhibits the expression of formylpeptide receptor and induces differentiation of malignant glioma cells.
Journal: Biochemical and biophysical research communications20060421
Title: Overcoming trastuzumab resistance with nordihydroguaiaretic acid?
Journal: Breast cancer research and treatment20060401
Title: Alpha-lipoic acid exhibits anti-amyloidogenicity for beta-amyloid fibrils in vitro.
Journal: Biochemical and biophysical research communications20060324
Title: Synthesis and structure-activity relationship studies of 1,3-diarylprop-2-yn-1-ones: dual inhibitors of cyclooxygenases and lipoxygenases.
Journal: Journal of medicinal chemistry20060309
Title: Protective effect of nordihydroguaiaretic acid (NDGA) against norgestrel induced genotoxic damage.
Journal: Toxicology in vitro : an international journal published in association with BIBRA20060301
Title: Differential effect of saturated, monounsaturated, and polyunsaturated fatty acids on alloxan-induced diabetes mellitus.
Journal: Prostaglandins, leukotrienes, and essential fatty acids20060301
Title: Schisandrene, a dibenzocyclooctadiene lignan from Schisandra chinensis: structure-antioxidant activity relationships of dibenzocyclooctadiene lignans.
Journal: Journal of natural products20060301
Title: Effects of nordihydroguaiaretic acid on Na+ currents in rat dorsal root ganglion neurons.
Journal: Brain research20060209
Title: Increased angiogenic capabilities of endothelial cells from microvessels of malignant human gliomas.
Journal: International immunopharmacology20060101
Title: Glucose metabolism in isolated uteri of immature rats. Influence of prostaglandins and nitric oxide.
Journal: Reproduction, nutrition, development20060101
Title: Blockade of arachidonic acid pathway induces sprouting in the adult but not in the neonatal uncrossed retinotectal projection.
Journal: Neuroscience20060101
Title: Purification, product characterization and kinetic properties of lipoxygenase from olive fruit (Olea europaea L.).
Journal: Plant physiology and biochemistry : PPB20060101
Title: Eicosanoid-mediated proinflammatory activity of Pseudomonas aeruginosa ExoU.
Journal: Cellular microbiology20051201
Title: Structure-activity relationship of polyphenols that inhibit fatty acid synthase.
Journal: Journal of biochemistry20051201
Title: Nordihydroguaiaretic acid (NDGA) inhibits the IGF-1 and c-erbB2/HER2/neu receptors and suppresses growth in breast cancer cells.
Journal: Breast cancer research and treatment20051101
Title: Synthesis and biological evaluation of 1,3-diphenylprop-2-yn-1-ones as dual inhibitors of cyclooxygenases and lipoxygenases.
Journal: Bioorganic & medicinal chemistry letters20051101
Title: Synthesis and antiinflammatory activity of coumarin derivatives.
Journal: Journal of medicinal chemistry20051006
Title: Role of arachidonic acid in hyposmotic membrane stretch-induced increase in calcium-activated potassium currents in gastric myocytes.
Journal: Acta pharmacologica Sinica20051001
Title: The anti-apoptotic effects of nordihydroguaiaretic acid: inhibition of cPLA(2) activation during TNF-induced apoptosis arises from inhibition of calcium signaling.
Journal: Life sciences20050923
Title: 15S-Lipoxygenase-2 mediates arachidonic acid-stimulated adhesion of human breast carcinoma cells through the activation of TAK1, MKK6, and p38 MAPK.
Journal: The Journal of biological chemistry20050909
Title: Conjugated linoleic acid, cis-9,trans-11, is a substrate for pulmonary 15-lipoxygenase-1 in rat.
Journal: Journal of agricultural and food chemistry20050907
Title: Effect of Larrea tridentata (creosote bush) on cholesterol gallstones and bile secretion in hamsters.
Journal: The Journal of pharmacy and pharmacology20050901
Title: 5-Lipoxygenase inhibitors attenuate growth of human renal cell carcinoma and induce apoptosis through arachidonic acid pathway.
Journal: Oncology reports20050701
Title: Systemic treatment with tetra-O-methyl nordihydroguaiaretic acid suppresses the growth of human xenograft tumors.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research20050615
Title: Determination and confirmation of five phenolic antioxidants in foods by LC/MS and GC/MS.
Journal: Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan20050601
Title: The effects of nitric oxide synthase--versus lipoxygenase inhibition on coronary flow and nitrite outflow in isolated rat heart.
Journal: General physiology and biophysics20050601
Title: Survival prolongation of microencapsulated allogeneic islet by nanosized nordihydroguaiaretic acid.
Journal: Transplantation proceedings20050501
Title: Larrea tridentata (Creosote bush), an abundant plant of Mexican and US-American deserts and its metabolite nordihydroguaiaretic acid.
Journal: Journal of ethnopharmacology20050426
Title: Leukotriene and prostaglandin synthesis pathways in osteoarthritic synovial membranes: regulating factors for interleukin 1beta synthesis.
Journal: The Journal of rheumatology20050401
Title: Nordihydroguaiaretic acid inhibits IFN-gamma-induced STAT tyrosine phosphorylation in rat brain astrocytes.
Journal: Biochemical and biophysical research communications20050311
Title: Nordihydroguaiaretic acid (NDGA) blocks the differentiation of C2C12 myoblast cells.
Journal: Journal of cellular physiology20050301
Title: Tryptamine and homotryptamine-based sulfonamides as potent and selective inhibitors of 15-lipoxygenase.
Journal: Bioorganic & medicinal chemistry letters20050301
Title: CDC2/CDK1 expression in esophageal adenocarcinoma and precursor lesions serves as a diagnostic and cancer progression marker and potential novel drug target.
Journal: The American journal of surgical pathology20050301
Title: Sensitization of colon cancer cell lines to butyrate-mediated proliferation inhibition by combined application of indomethacin and nordihydroguaiaretic acid.
Journal: Cancer detection and prevention20050101
Title: Inhibition of influenza-virus-induced apoptosis in chorion cells of human fetal membranes by nordihydroguaiaretic Acid.
Journal: Intervirology20050101
Title: Anti-inflammatory effects of specific cyclooxygenase 2,5-lipoxygenase, and inducible nitric oxide synthase inhibitors on experimental autoimmune anterior uveitis (EAAU).
Journal: Ocular immunology and inflammation20050101
Title: The histone deacetylase inhibitor suberoylanilide hydroxamic acid induces apoptosis via induction of 15-lipoxygenase-1 in colorectal cancer cells.
Journal: Cancer research20041201
Title: New acylated iridoid glucosides from Vitex altissima.
Journal: Journal of natural products20041201
Title: Group IIA secretory phospholipase A2 is a unique 12/15-lipoxygenase-regulated gene in cytokine-stimulated rat fibroblastic 3Y1 cells.
Journal: Biochimica et biophysica acta20041108
Title: Anti-amyloidogenic activity of tannic acid and its activity to destabilize Alzheimer's beta-amyloid fibrils in vitro.
Journal: Biochimica et biophysica acta20041105
Title: Suppression of heat- and polyglutamine-induced cytotoxicity by nonsteroidal anti-inflammatory drugs.
Journal: European journal of biochemistry20041101
Title: Arachidonic acid regulation of steroid synthesis: new partners in the signaling pathway of steroidogenic hormones.
Journal: Endocrine research20041101
Title: Multiple contributions from long-chain fatty acid metabolism in Y-1 and MA-10 cells.
Journal: Endocrine research20041101
Title: The arachidonic acid 5-lipoxygenase inhibitor nordihydroguaiaretic acid inhibits tumor necrosis factor alpha activation of microglia and extends survival of G93A-SOD1 transgenic mice.
Journal: Journal of neurochemistry20041001
Title: Nordihydroguaiaretic acid-induced Ca2+ handling and cytotoxicity in human prostate cancer cells.
Journal: Life sciences20040924
Title: Lignoids in insects: chemical probes for the study of ecdysis, excretion and Trypanosoma cruzi-triatomine interactions.
Journal: Toxicon : official journal of the International Society on Toxinology20040915
Title: Nordihydroguairetic acid, a lignin, prevents oxidative stress and the development of diabetic nephropathy in rats.
Journal: Pharmacology20040901
Title: Nordihydroguaiaretic acid does not disaggregate beta-amyloid(1-40) protofibrils but does inhibit growth arising from direct protofibril association.
Journal: Molecular pharmacology20040901
Title: Stimulatory actions of caffeic acid phenethyl ester, a known inhibitor of NF-kappaB activation, on Ca2+-activated K+ current in pituitary GH3 cells.
Journal: The Journal of biological chemistry20040625
Title: A new lead compound for abscisic acid biosynthesis inhibitors targeting 9-cis-epoxycarotenoid dioxygenase.
Journal: Bioorganic & medicinal chemistry letters20040621
Title: Prostaglandin F(2alpha) is protective for apoptosis stimulated synergistically with 12-O-tetradecanoyl phorbol-beta-acetate and nordihydroguaiaretic acid in Madin-Darby canine kidney cells.
Journal: Biochimica et biophysica acta20040601
Title: Effect of Larrea divaricata Cav. extract and nordihydroguaiaretic acid upon peroxidase secretion in rat submandibulary glands.
Journal: Pharmacological research20040501
Title: Inhibitors of 5-lipoxygenase inhibit expression of intercellular adhesion molecule-1 in human melanoma cells.
Journal: Acta pharmacologica Sinica20040501
Title: BK2 but not BK1 receptors mediating contractile response in human umbilical arteries: role of thromboxane A2.
Journal: Methods and findings in experimental and clinical pharmacology20040501
Title: Involvement of spinal lipoxygenase metabolites in hyperalgesia and opioid tolerance.
Journal: European journal of pharmacology20040426
Title: Substance P can stimulate prostaglandin D2 and leukotriene C4 generation without granule exocytosis in murine mast cells.
Journal: European journal of pharmacology20040405
Title: Interleukin-17 signal transduction pathways implicated in inducing matrix metalloproteinase-3, -13 and aggrecanase-1 genes in articular chondrocytes.
Journal: Cellular signalling20040401
Title: Inhibition of AP-1 transcription activator induces myc-dependent apoptosis in HL60 cells.
Journal: Journal of cellular biochemistry20040401
Title: A stepwise dissection of the intracellular fate of cationic cell-penetrating peptides.
Journal: The Journal of biological chemistry20040326
Title: Curcumin has potent anti-amyloidogenic effects for Alzheimer's beta-amyloid fibrils in vitro.
Journal: Journal of neuroscience research20040315
Title: Adipocyte differentiation of multipotent cells established from human adipose tissue.
Journal: Biochemical and biophysical research communications20040305
Title: Determination of binding constant of transcription factor myc-max/max-max and E-box DNA: the effect of inhibitors on the binding.
Journal: Biochimica et biophysica acta20040224
Title: The effects of TNF-alpha and inhibitors of arachidonic acid metabolism on human colon HT-29 cells depend on differentiation status.
Journal: Differentiation; research in biological diversity20040201
Title: TGSA-Flex: Extending the capabilities of the Topo-Geometrical Superposition Algorithm to handle flexible molecules.
Journal: Journal of computational chemistry20040130
Title: Estrogenic activity of an antioxidant, nordihydroguaiaretic acid (NDGA).
Journal: Life sciences20040130
Title: Differential and special properties of the major human UGT1-encoded gastrointestinal UDP-glucuronosyltransferases enhance potential to control chemical uptake.
Journal: The Journal of biological chemistry20040109
Title: Tetrapetalone A, a novel lipoxygenase inhibitor from Streptomyces sp.
Journal: Bioscience, biotechnology, and biochemistry20040101
Title: Effects of eicosanoid biosynthesis inhibitors on the prophenoloxidase-activating system and microaggregation reactions in the hemolymph of Rhodnius prolixus infected with Trypanosoma rangeli.
Journal: Journal of insect physiology20040101
Title: 15-LOX-1 inhibits p21 (Cip/WAF 1) expression by enhancing MEK-ERK 1/2 signaling in colon carcinoma cells.
Journal: Prostaglandins & other lipid mediators20040101
Title: Inhibitory action of ICI-182,780, an estrogen receptor antagonist, on BK(Ca) channel activity in cultured endothelial cells of human coronary artery.
Journal: Biochemical pharmacology20031115
Title: Dihydrolipoic acid inhibits 15-lipoxygenase-dependent lipid peroxidation.
Journal: Free radical biology & medicine20031115
Title: Lipoxygenase inhibitors enhance tumor suppressive effects of jun proteins on v-myb-transformed monoblasts BM2.
Journal: Prostaglandins & other lipid mediators20031101
Title: Adipocyte differentiation of 3T3-L1 preadipocytes is dependent on lipoxygenase activity during the initial stages of the differentiation process.
Journal: The Biochemical journal20031101
Title: Naturally occurring lignans efficiently induce apoptosis in colorectal tumor cells.
Journal: Journal of cancer research and clinical oncology20031001
Title: Nordihydroguaiaretic acid, an antioxidant, inhibits transforming growth factor-beta activity through the inhibition of Smad signaling pathway.
Journal: Experimental cell research20031001
Title: Study of 202 natural, synthetic, and environmental chemicals for binding to the androgen receptor.
Journal: Chemical research in toxicology20031001
Title: The role of oxidant-mediated pathways in the cytotoxicity of endothelial cells exposed to mesenteric lymph from rats subjected to trauma-hemorrhagic shock.
Journal: Shock (Augusta, Ga.)20030901
Title: Spinal administration of lipoxygenase inhibitors suppresses behavioural and neurochemical manifestations of naloxone-precipitated opioid withdrawal.
Journal: British journal of pharmacology20030901
Title: Nitric oxide triggers the toxicity due to glutathione depletion in midbrain cultures through 12-lipoxygenase.
Journal: The Journal of biological chemistry20030613
Title: Roles of 5-lipoxygenase activating protein in cell proliferation and apoptosis.
Journal: Cell biology and toxicology20030601
Title: Neuroprotection by the endogenous cannabinoid anandamide and arvanil against in vivo excitotoxicity in the rat: role of vanilloid receptors and lipoxygenases.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20030515
Title: Fatty acid release and oxidation are factors in lipoxygenase inhibitor-induced apoptosis.
Journal: Toxicology letters20030303
Title: Mechanical and thermal properties of novel polymerized NDGA-gelatin hydrogels.
Journal: Biomaterials20030301
Title: Inhibition of HSV-1 replication and reactivation by the mutation-insensitive transcription inhibitor tetra-O-glycyl-nordihydroguaiaretic acid.
Journal: Antiviral research20030301
Title: Novel antiviral agent tetraglycylated nordihydroguaiaretic acid hydrochloride as a host-dependent viral inhibitor.
Journal: Antiviral research20030301
Title: Oxidant-stimulated chloride secretion in rat jejunum in vitro is mediated by eicosanoids.
Journal: Digestive diseases and sciences20030301
Title: Direct interaction of the Golgi membrane with the endoplasmic reticulum membrane caused by nordihydroguaiaretic acid.
Journal: Biochemical and biophysical research communications20030221
Title: Inhibition by eicosapentaenoic acid of IL-1beta-induced PGHS-2 expression in human microvascular endothelial cells: involvement of lipoxygenase-derived metabolites and p38 MAPK pathway.
Journal: Biochimica et biophysica acta20030220
Title: Abnormalities in intracellular Ca2+ regulation in fetal vascular smooth muscle in pre-eclampsia: enhanced sensitivity to arachidonic acid.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology20030201
Title: Contribution of 5- and 12-lipoxygenase products to mechanical hyperalgesia induced by prostaglandin E(2) and epinephrine in the rat.
Journal: Experimental brain research20030201
Title: Lipoxygenase products regulate nitric oxide and inducible nitric oxide synthase production in interleukin-1beta stimulated vascular smooth muscle cells.
Journal: Hypertension research : official journal of the Japanese Society of Hypertension20030201
Title: Mepanipyrim, a novel inhibitor of pharmacologically induced Golgi dispersion.
Journal: Bioscience, biotechnology, and biochemistry20030101
Title: Nordihydroguaiaretic acid, of a new family of microtubule-stabilizing agents, shows effects differentiated from paclitaxel.
Journal: Bioscience, biotechnology, and biochemistry20030101
Title: Eicosanoid precursor polyenoic fatty acids modulate synaptic levels of dopamine in ex-vivo slices of rat brain striatum.
Journal: In vivo (Athens, Greece)20030101
Title: [Effect of inhibitors of cyclooxygenase and lypoxygenase pathway of metabolism of arachidonic acid on the development and suppression of the immune response in mice].
Journal: Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994)20030101
Title: Lipoxygenase inhibitors suppress proliferation of G5:113 fibrosarcoma cells in vitro but they have no anticancer activity in vivo.
Journal: Neoplasma20030101
Title: Prostaglandin F2alpha protected cultured Madin-Darby canine kidney cells from the development of apoptosis induced by 12-o-tetradecanoyl phorbol-beta-acetate and stimulated synergistically with nordihydroguaiaretic acid.
Journal: Advances in experimental medicine and biology20030101
Title: BAD and Bcl-2 regulation are early events linking neuronal endoplasmic reticulum stress to mitochondria-mediated apoptosis.
Journal: Brain research. Molecular brain research20021230
Title: Nordihydroguaiaretic acid: hepatotoxicity and detoxification in the mouse.
Journal: Toxicon : official journal of the International Society on Toxinology20021201
Title: Aberrant arachidonic acid metabolism in esophageal adenocarcinogenesis, and the effects of sulindac, nordihydroguaiaretic acid, and alpha-difluoromethylornithine on tumorigenesis in a rat surgical model.
Journal: Carcinogenesis20021201
Title: Concerted regulation of free arachidonic acid and hormone-induced steroid synthesis by acyl-CoA thioesterases and acyl-CoA synthetases in adrenal cells.
Journal: European journal of biochemistry20021101
Title: ACTH regulation of mitochondrial acyl-CoA thioesterase activity in Y1 adrenocortical tumour cells.
Journal: Endocrine research20021101
Title: Effect of nordihydroguaiaretic acid on intracellular Ca(2+) concentrations in hepatocytes.
Journal: Toxicology in vitro : an international journal published in association with BIBRA20021001
Title: Effect of nordihydroguaiaretic acid on the secretion of lipoprotein lipase.
Journal: Journal of biochemistry and molecular biology20020930
Title: Inhibition of peroxisome proliferator-activated receptor (PPAR)-mediated keratinocyte differentiation by lipoxygenase inhibitors.
Journal: The Biochemical journal20020915
Title: Design, synthesis, and biological evaluation of a cephalosporin-monohydroguaiaretic acid prodrug activated by a monoclonal antibody-beta-lactamase conjugate.
Journal: Bioorganic & medicinal chemistry20020901
Title: N-acylethanolamines are metabolized by lipoxygenase and amidohydrolase in competing pathways during cottonseed imbibition.
Journal: Plant physiology20020901
Title: Neurons overexpressing mutant presenilin-1 are more sensitive to apoptosis induced by endoplasmic reticulum-Golgi stress.
Journal: Journal of neuroscience research20020815
Title: Structure-activity relationship studies of nordihydroguaiaretic acid inhibitors toward soybean, 12-human, and 15-human lipoxygenase.
Journal: Journal of medicinal chemistry20020606
Title: Induction of MnSOD gene by arachidonic acid is mediated by reactive oxygen species and p38 MAPK signaling pathway in human HepG2 hepatoma cells.
Journal: Free radical biology & medicine20020601
Title: Participation of the arachidonic acid cascade pathway in macrophage binding/uptake of oxidized low density lipoprotein.
Journal: Biological & pharmaceutical bulletin20020601
Title: Nordihydroguaiaretic acid-mediated inhibition of ultraviolet B-induced activator protein-1 activation in human keratinocytes.
Journal: Molecular carcinogenesis20020601
Title: Effects of brefeldin A and nordihydroguaiaretic acid on endomembrane dynamics and lipid synthesis in plant cells.
Journal: FEBS letters20020508
Title: Effects of cyclooxygenase and lipoxygenase inhibition on basal- and serotonin-induced ion transport in rat colon.
Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP20020501
Title: Involvement of glycogen synthase kinase-3beta and tau phosphorylation in neuronal Golgi disassembly.
Journal: Journal of neurochemistry20020501
Title: Nordihydroguaiaretic acid potently breaks down pre-formed Alzheimer's beta-amyloid fibrils in vitro.
Journal: Journal of neurochemistry20020501
Title: Mechanisms underlying the activation of large conductance Ca2+-activated K+ channels by nordihydroguaiaretic acid.
Journal: Japanese journal of pharmacology20020501
Title: Mechanisms of nordihydroguaiaretic acid-induced growth inhibition and apoptosis in human cancer cells.
Journal: British journal of cancer20020408
Title: [Simultaneous determination of five antioxidants in food by HPLC with fluorescence detection].
Journal: Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan20020401
Title: Comparative quantitative structure toxicity relationships for flavonoids evaluated in isolated rat hepatocytes and HeLa tumor cells.
Journal: Chemico-biological interactions20020320
Title: Effect of nordihydroguaiaretic acid on intracellular Ca(2+) concentrations in C6 glioma cells.
Journal: Neurochemistry international20020301
Title: Possible implication of Golgi-nucleating function for the centrosome.
Journal: Biochemical and biophysical research communications20020301
Title: Expression and induction of the stress protein alpha-B-crystallin in vascular endothelial cells.
Journal: Histochemistry and cell biology20020301
Title: Effects of inhibitors of the lipo-oxygenase family of enzymes on the store-operated calcium current I(CRAC) in rat basophilic leukaemia cells.
Journal: The Journal of physiology20020215
Title: Tending tender tendons.
Journal: Science (New York, N.Y.)20020208
Title: 5-Lipoxygenase and human pulmonary artery endothelial cell proliferation.
Journal: American journal of physiology. Heart and circulatory physiology20020201
Title: Differential effect of brefeldin A on the palmitoylation of surfactant protein C proprotein mutants.
Journal: Biochemical and biophysical research communications20020111
Title: The lipoxygenase pathways are involved in LH-stimulated progesterone production in bovine corpus luteum.
Journal: Prostaglandins & other lipid mediators20020101
Title: Cytosolic phospholipase A2 and lipoxygenase are involved in cell cycle progression in neuroblastoma cells.
Journal: Cellular and molecular life sciences : CMLS20020101
Title: [Effect of exogenous leukotrienes and lipoxygenase inhibitors on apoptosis and necrosis in cultured rat hepatocytes].
Journal: Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994)20020101
Title: [Lipoxygenase inhibitors induce rat hepatocyte apoptosis in primary culture].
Journal: Ukrains'kyi biokhimichnyi zhurnal (1999 )20020101
Title: Regulation of apoptosis through arachidonate cascade in mammalian cells.
Journal: Applied biochemistry and biotechnology20020101
Title: Lipoxygenase inhibitors induce arrest of tumor cells in S-phase of the cell cycle.
Journal: Neoplasma20020101
Title: Progressive apoptosis in chorion laeve trophoblast cells of human fetal membrane tissues during in vitro incubation is suppressed by antioxidative reagents.
Journal: European journal of biochemistry20011201
Title: Nordihydroguaiaretic acid elevates osteoblastic intracellular Ca2+.
Journal: Pharmacology & toxicology20011201
Title: Synthesis and anticancer activity of nordihydroguaiaretic acid (NDGA) and analogues.
Journal: Anti-cancer drug design20011201
Title: Lipoxygenase inhibitors inhibit heparin-releasable lipoprotein lipase activity in 3T3-L1 adipocytes and enhance body fat reduction in mice by conjugated linoleic acid.
Journal: Biochimica et biophysica acta20011130
Title: 5-lipoxygenase regulates malignant mesothelial cell survival: involvement of vascular endothelial growth factor.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology20011101
Title: Intracellular signaling pathway of FGF-2-modulated corneal endothelial cell migration during wound healing in vitro.
Journal: Experimental eye research20011101
Title: Eicosanoids participate in the regulation of cardiac glucose transport by contribution to a rearrangement of actin cytoskeletal elements.
Journal: The Biochemical journal20011001
Title: Histamine stimulates alveolar macrophages to release neutrophil and monocyte chemotactic activity.
Journal: The Journal of laboratory and clinical medicine20011001
Title: tetra-O-methylnordihydroguaiaretic acid inhibits melanoma in vivo.
Journal: Cancer letters20010928
Title: trans-10,cis-12-Conjugated linoleic acid reduces leptin secretion from 3T3-L1 adipocytes.
Journal: Biochemical and biophysical research communications20010921
Title: Differential role of cytosolic phospholipase A2 in the invasion of brain microvascular endothelial cells by Escherichia coli and Listeria monocytogenes.
Journal: The Journal of infectious diseases20010915
Title: Elevating dietary salt exacerbates hyperpnea-induced airway obstruction in guinea pigs.
Journal: Journal of applied physiology (Bethesda, Md. : 1985)20010901
Title: Pharmacological modulation of allergic inflammation in the rat airways and association with mast cell heterogeneity.
Journal: European journal of pharmacology20010824
Title: Johns Hopkins embroiled in fresh misconduct allegations.
Journal: Nature20010802
Title: Characterization of clofibrate-induced retrograde Golgi membrane movement to the endoplasmic reticulum: clofibrate distinguishes the Golgi from the trans Golgi network.
Journal: Bioscience, biotechnology, and biochemistry20010801
Title: Baicalein protects cortical neurons from beta-amyloid (25-35) induced toxicity.
Journal: Neuroreport20010720
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