Title: Novel bis-, tris-, and tetrakis-tertiary amino analogs as antagonists at neuronal nicotinic receptors that mediate nicotine-evoked dopamine release.
Journal: Bioorganic & medicinal chemistry letters 20110101
Title: Repeated nicotine administration robustly increases bPiDDB inhibitory potency at alpha6beta2-containing nicotinic receptors mediating nicotine-evoked dopamine release.
Journal: Biochemical pharmacology 20100801
Title: Bis-azaaromatic quaternary ammonium salts as ligands for the blood-brain barrier choline transporter.
Journal: Bioorganic & medicinal chemistry letters 20100601
Title: Novel bis-2,2,6,6-tetramethylpiperidine (bis-TMP) and bis-mecamylamine antagonists at neuronal nicotinic receptors mediating nicotine-evoked dopamine release.
Journal: Bioorganic & medicinal chemistry letters 20100215
Title: Predictive screening model for potential vector-mediated transport of cationic substrates at the blood-brain barrier choline transporter.
Journal: Bioorganic & medicinal chemistry letters 20100201
Title: The novel nicotinic receptor antagonist, N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide (bPiDDB), inhibits nicotine-evoked [(3)H]norepinephrine overflow from rat hippocampal slices.
Journal: Biochemical pharmacology 20091001
Title: QSAR study on maximal inhibition (Imax) of quaternary ammonium antagonists for S-(-)-nicotine-evoked dopamine release from dopaminergic nerve terminals in rat striatum.
Journal: Bioorganic & medicinal chemistry 20090701
Title: Targeting reward-relevant nicotinic receptors in the discovery of novel pharmacotherapeutic agents to treat tobacco dependence.
Journal: Nebraska Symposium on Motivation. Nebraska Symposium on Motivation 20090101
Title: Targeting nicotinic receptor antagonists as novel pharmacotherapies for tobacco dependence and relapse.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20090101
Title: The novel nicotinic receptor antagonist N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide decreases nicotine-induced dopamine metabolism in rat nucleus accumbens.
Journal: European journal of pharmacology 20081228
Title: Tetrakis-azaaromatic quaternary ammonium salts: novel subtype-selective antagonists at neuronal nicotinic receptors that mediate nicotine-evoked dopamine release.
Journal: Bioorganic & medicinal chemistry letters 20081101
Title: bis-Pyridinium cyclophanes: novel ligands with high affinity for the blood-brain barrier choline transporter.
Journal: Bioorganic & medicinal chemistry letters 20081015
Title: Pharmacokinetics of the novel nicotinic receptor antagonist N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide in the rat.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20081001
Title: N,N'-Alkane-diyl-bis-3-picoliniums as nicotinic receptor antagonists: inhibition of nicotine-evoked dopamine release and hyperactivity.
Journal: The Journal of pharmacology and experimental therapeutics 20080801
Title: Region-specific effects of N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide on nicotine-induced increase in extracellular dopamine in vivo.
Journal: British journal of pharmacology 20080201
Title: Carrier-mediated transport of the quaternary ammonium neuronal nicotinic receptor antagonist n,n'-dodecylbispicolinium dibromide at the blood-brain barrier.
Journal: The Journal of pharmacology and experimental therapeutics 20080101
Title: Tris-azaaromatic quaternary ammonium salts: Novel templates as antagonists at nicotinic receptors mediating nicotine-evoked dopamine release.
Journal: Bioorganic & medicinal chemistry letters 20071215
Title: Bis-azaaromatic quaternary ammonium salts as antagonists at nicotinic receptors mediating nicotine-evoked dopamine release: An investigation of binding conformation.
Journal: Bioorganic & medicinal chemistry letters 20071215
Title: The effects of a novel nicotinic receptor antagonist N,N-dodecane-1,12-diyl-bis-3-picolinium dibromide (bPiDDB) on acute and repeated nicotine-induced increases in extracellular dopamine in rat nucleus accumbens.
Journal: Neuropharmacology 20070301
Title: Effect of a novel nicotinic receptor antagonist, N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide, on nicotine self-administration and hyperactivity in rats.
Journal: Psychopharmacology 20060301
Title: Subtype-selective nicotinic receptor antagonists: potential as tobacco use cessation agents.
Journal: Bioorganic & medicinal chemistry letters 20040419
Title: bis-Azaaromatic quaternary ammonium analogues: ligands for alpha4beta2* and alpha7* subtypes of neuronal nicotinic receptors.
Journal: Bioorganic & medicinal chemistry letters 20021104