Name: Name:Brl 54443
Brand: AABLOCKS
SKU: AA00ECA9
Rating: 90 (10 reviews)

Catalog No.: AA00ECA9

57477-39-1 | Brl 54443

Pack Size： 25mg

Purity： 98%

in stock

$54.00 $38.00

Pack Size： 100mg

Purity： 98%

in stock

$120.00 $84.00

Pack Size： 250mg

Purity： 98%

in stock

$234.00 $164.00

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Technical Information

Catalog Number: AA00ECA9

Chemical Name: Brl 54443

CAS Number: 57477-39-1

Molecular Formula: C14H18N2O

Molecular Weight: 230.3055

MDL Number: MFCD01861184

SMILES: CN1CCC(CC1)c1c[nH]c2c1cc(O)cc2

Properties

Complexity: 263

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 17

Hydrogen Bond Acceptor Count: 2

Hydrogen Bond Donor Count: 2

Isotope Atom Count: 0

Rotatable Bond Count: 1

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 1.5

Literature fold

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry20020419

Title: Klein MT, et al. Toward selective drug development for the human 5-hydroxytryptamine 1E receptor: a comparison of 5-hydroxytryptamine 1E and 1F receptor structure-affinity relationships. J Pharmacol Exp Ther. 2011 Jun;337(3):860-867.

Title: McKune CM, et al. Characterization of the serotonin receptor mediating contraction in the mouse thoracic aorta and signal pathway coupling. J Pharmacol Exp Ther. 2001 Apr;297(1):88-95.

Title: Klein MT, et al. Distribution of 5-ht(1E) receptors in the mammalian brain and cerebral vasculature: an immunohistochemical and pharmacological study. Br J Pharmacol. 2012 Jun;166(4):1290-302.

Title: Granados-Soto V, et al. The role of peripheral 5-HT1A, 5-HT1B, 5-HT1D, 5-HT1E and 5-HT1F serotonergic receptors in the reduction of nociception in rats. Neuroscience. 2010 Jan 20;165(2):561-8.