Title: Chemical profiling of the genome with anti-cancer drugs defines target specificities.
Journal: Nature chemical biology20150701
Title: Drug-induced histone eviction from open chromatin contributes to the chemotherapeutic effects of doxorubicin.
Journal: Nature communications20130528
Title: In vitro antifungal activity of DNA topoisomerase inhibitors.
Journal: Medical mycology20120401
Title: Low-dose cytarabine plus aclarubicin for patients with previously untreated acute myeloid leukemia or high-risk myelodysplastic syndrome ineligible for standard-dose cytarabine plus anthracycline.
Journal: Anticancer research20120401
Title: Aclarubicin enhances tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis through death receptor 5 upregulation.
Journal: Cancer science20120201
Title: [CAG-GO therapy for patients with relapsed or primary refractory CD33-positive acute myelogenous leukemia].
Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology20120101
Title: Discovery, synthesis, and biological evaluation of novel SMN protein modulators.
Journal: Journal of medicinal chemistry20110922
Title: Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2.
Journal: Journal of medicinal chemistry20110714
Title: Salvage chemotherapy with low-dose cytarabine and aclarubicin in combination with granulocyte colony-stimulating factor priming in patients with refractory or relapsed acute myeloid leukemia with translocation (8;21).
Journal: Leukemia research20110501
Title: [The efficacy and safety of HAA regimen as induction chemotherapy in 150 newly diagnosed acute myeloid leukemia].
Journal: Zhonghua nei ke za zhi20110101
Title: A meta-analysis of CAG (cytarabine, aclarubicin, G-CSF) regimen for the treatment of 1029 patients with acute myeloid leukemia and myelodysplastic syndrome.
Journal: Journal of hematology & oncology20110101
Title: Aclarubicin-induced apoptosis and necrosis in cells derived from human solid tumours.
Journal: Mutation research20100719
Title: Low-dose cytarabine and aclarubicin in combination with granulocyte colony-stimulating factor for elderly patients with previously untreated acute myeloid leukemia.
Journal: Leukemia research20100501
Title: [Curative effect of low dose cytarabine and aclarubin in combination with granulocyte colony-stimulating factor priming (CAG regimen) on patients with the intermediate and high-risk myelodysplastic syndrome].
Journal: Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences20100401
Title: Homoharringtonine in combination with cytarabine and aclarubicin as induction therapy improves remission and survival of patients with higher risk myelodysplastic syndromes.
Journal: Chinese medical journal20100105
Title: Comparative analysis of remission induction therapy for high-risk MDS and AML progressed from MDS in the MDS200 study of Japan Adult Leukemia Study Group.
Journal: International journal of hematology20100101
Title: Catalytic activity of the proteasome fine-tunes Brg1-mediated chromatin remodeling to regulate the expression of inflammatory genes.
Journal: Molecular immunology20091201
Title: [beta-elemene enhances aclarubicin-induced apoptotic effect in HL-60 cells and its mechanism.].
Journal: Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi20091201
Title: Multiple hepatocellular carcinomas developed 15 months after commencement of chemotherapy for elderly acute myelogenous leukemia.
Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology20091101
Title: Outcomes of CAG regimen for refractory biphenotypic acute leukemia patients.
Journal: Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih20090901
Title: [Clinical research of modified CAG regimen for the treatment of relapsed acute myeloid leukemia].
Journal: Zhongguo shi yan xue ye xue za zhi20090801
Title: [Low-dose cytarabine and aclarubicin in combination with granulocyte colony-stimulating factor priming in 50 patients with relapsed acute myeloid leukemia].
Journal: Zhongguo shi yan xue ye xue za zhi20090601
Title: Discovery of selective glucocorticoid receptor modulators by multiplexed reporter screening.
Journal: Proceedings of the National Academy of Sciences of the United States of America20090324
Title: The inhibitory effect of the proinflammatory cytokine TNFalpha on erythroid differentiation involves erythroid transcription factor modulation.
Journal: International journal of oncology20090301
Title: Treatment of therapy-related acute myeloid leukemia occurring in elderly non-Hodgkin lymphoma patients with low-dose cytarabine, aclarubicin and granulocyte colony-stimulating factor.
Journal: Leukemia research20090101
Title: [Mechanism of CAG regimen eliminating T-cell acute lymphoblastic leukemia A3 cell line].
Journal: Zhongguo shi yan xue ye xue za zhi20081201
Title: Successful combination therapy with infusion of allogenetic bone marrow mesenchymal stem cells and CAG regimen in hypoplastic relapsed acute myelogenous leukemia.
Journal: Leukemia research20081101
Title: Selective delivery of folate-PEG-linked, nanoemulsion-loaded aclacinomycin A to KB nasopharyngeal cells and xenograft: effect of chain length and amount of folate-PEG linker.
Journal: Journal of drug targeting20081101
Title: Aclarubicin-induced ROS generation and collapse of mitochondrial membrane potential in human cancer cell lines.
Journal: Chemico-biological interactions20081022
Title: Extensive intracellular accumulation of ID-6105, a novel anthracycline, in SK-OV-3 ovarian cancer cells.
Journal: Archives of pharmacal research20081001
Title: Moromycins A and B, isolation and structure elucidation of C-glycosylangucycline-type antibiotics from Streptomyces sp. KY002.
Journal: Journal of natural products20080901
Title: [Prognosis analysis of 83 cases of cervical adenosquamous carcinoma].
Journal: Ai zheng = Aizheng = Chinese journal of cancer20080901
Title: [Therapeutic effect of priming induction regimen of CAG for newly diagnosed acute myeloid leukemia in elderly patients].
Journal: Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences20080301
Title: CAG regimen enables relapsed or refractory T-cell acute lymphocytic leukemia patients to achieve complete remission: a report of six cases.
Journal: American journal of hematology20080201
Title: [HAA regimen as induction chemotherapy for newly diagnosed acute myelogenous leukemia].
Journal: Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi20080101
Title: Effect of low-dose cytarabine and aclarubicin in combination with granulocyte colony-stimulating factor priming (CAG regimen) on the outcome of elderly patients with acute myeloid leukemia.
Journal: Leukemia research20071001
Title: Involvement of reactive oxygen species in aclarubicin-induced death of human trisomic and diabetic fibroblasts.
Journal: Toxicology in vitro : an international journal published in association with BIBRA20070901
Title: Analysis of aclarubicin-induced cell death in human fibroblasts.
Journal: Cell biology international20070901
Title: Characterization of rhodosaminyl transfer by the AknS/AknT glycosylation complex and its use in reconstituting the biosynthetic pathway of aclacinomycin A.
Journal: Journal of the American Chemical Society20070829
Title: BRCA1- and BRCA2-deficient cells are sensitive to etoposide-induced DNA double-strand breaks via topoisomerase II.
Journal: Cancer research20070801
Title: Apoptosis induced by ID6105, a new anthracycline (11-hydroxyaclacinomycin X, Hyrubicin), and its anti-tumor effects on experimental tumor models.
Journal: Cancer chemotherapy and pharmacology20070701
Title: [Acute myelogenous leukemia with multilineage myelodysplasia, positive direct Coombs test, and elevated levels of platelet-associated IgG].
Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology20070501
Title: Aclacinomycin oxidoreductase (AknOx) from the biosynthetic pathway of the antibiotic aclacinomycin is an unusual flavoenzyme with a dual active site.
Journal: Proceedings of the National Academy of Sciences of the United States of America20070410
Title: Stat5 constitutive activation rescues defects in spinal muscular atrophy.
Journal: Human molecular genetics20070301
Title: Structure determination by multiwavelength anomalous diffraction of aclacinomycin oxidoreductase: indications of multidomain pseudomerohedral twinning.
Journal: Acta crystallographica. Section D, Biological crystallography20070201
Title: Aclarubicin-loaded cationic albumin-conjugated pegylated nanoparticle for glioma chemotherapy in rats.
Journal: International journal of cancer20070115
Title: Induction of remission of relapsed acute myeloid leukemia after unrelated donor cord blood transplantation by concomitant low-dose cytarabine and calcitriol in adults.
Journal: European journal of haematology20061001
Title: Aclarubicin plus behenoyl cytarabine and prednisolone for previously treated acute myeloid leukemia patients.
Journal: Leukemia & lymphoma20061001
Title: [Studies on aclacinomycin spectral characters and the interaction between aclacinomycin and DNA by spectroscopic method].
Journal: Guang pu xue yu guang pu fen xi = Guang pu20060901
Title: Tumor necrosis factor alpha inhibits aclacinomycin A-induced erythroid differentiation of K562 cells via GATA-1.
Journal: Cancer letters20060828
Title: Homoharringtonine in combination with cytarabine and aclarubicin resulted in high complete remission rate after the first induction therapy in patients with de novo acute myeloid leukemia.
Journal: Leukemia20060801
Title: Combined effect of low-power laser irradiation and anthraquinone anticancer drug aclarubicin on survival of immortalized cells: Comparison with mitoxantrone.
Journal: Cell biology international20060801
Title: Modulation of radiation response by inhibiting topoisomerase II catalytic activity.
Journal: Mutation research20060725
Title: In vivo antitumor efficacy and cardiotoxicity of novel anthracycline ID6105 (11-hydroxy-aclacinomycin X, Hyrubicin).
Journal: Cancer chemotherapy and pharmacology20060601
Title: Successful reduced-intensity stem cell transplantation in a patient with myelodysplastic syndrome combined with Sweet's syndrome.
Journal: Hematology (Amsterdam, Netherlands)20060601
Title: Crystal structure of the polyketide cyclase AknH with bound substrate and product analogue: implications for catalytic mechanism and product stereoselectivity.
Journal: Journal of molecular biology20060317
Title: Acute myeloblastic leukemia in a patient with hereditary protein C deficiency.
Journal: Internal medicine (Tokyo, Japan)20060101
Title: SR proteins as potential targets for therapy.
Journal: Progress in molecular and subcellular biology20060101
Title: Mechanisms of induction of apoptosis by anthraquinone anticancer drugs aclarubicin and mitoxantrone in comparison with doxorubicin: relation to drug cytotoxicity and caspase-3 activation.
Journal: Apoptosis : an international journal on programmed cell death20051201
Title: Neoglycorandomization and chemoenzymatic glycorandomization: two complementary tools for natural product diversification.
Journal: Journal of natural products20051101
Title: Engineered biosynthesis of aklanonic acid analogues.
Journal: Journal of the American Chemical Society20050907
Title: [Transfection of HL-60 cells with CYP3A5 gene induces drug-resistant phenotype].
Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology]20050801
Title: Aclarubicin and low-dose Cytosine arabinoside in combination with granulocyte colony-stimulating factor in treating acute myeloid leukemia patients with relapsed or refractory disease and myelodysplastic syndrome: a multicenter study of 112 Chinese patients.
Journal: International journal of hematology20050701
Title: Induction of genotoxic and cytotoxic damage by aclarubicin, a dual topoisomerase inhibitor.
Journal: Mutation research20050502
Title: AknT is an activating protein for the glycosyltransferase AknS in L-aminodeoxysugar transfer to the aglycone of aclacinomycin A.
Journal: Chemistry & biology20050501
Title: HPLC analysis and pharmacokinetic characteristics of 11-hydroxyaclacinomycin X (ID-6105), a novel anthracycline, in rats and beagle dogs.
Journal: Biological & pharmaceutical bulletin20050401
Title: [Sensitivity of survivin-positive primary leukemia cells to chemotherapy].
Journal: Zhongguo shi yan xue ye xue za zhi20050401
Title: Pharmacokinetics of 11-hydroxyaclacinomycin X (ID-6105), a novel anthracycline, after i.v. bolus multiple administration in rats.
Journal: Archives of pharmacal research20050401
Title: Effect of polyethylene glycol linker chain length of folate-linked microemulsions loading aclacinomycin A on targeting ability and antitumor effect in vitro and in vivo.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research20050301
Title: High-density lipoprotein as a potential carrier for delivery of a lipophilic antitumoral drug into hepatoma cells.
Journal: World journal of gastroenterology20050221
Title: Induction of fetal haemoglobin expression in erythroid cells--a model based on iron availability signalling.
Journal: Medical hypotheses20050101
Title: Successful treatment of a patient with synchronous advanced non-small cell lung cancer and acute myeloid leukemia by a combination of gefitinib, low-dose cytarabine and aclarubicin.
Journal: Anticancer research20050101
Title: [Study on the relationship between the inhibitors of apoptosis proteins and the apoptosis of myelodysplastic syndrome cell line cells induced by aclacinomycin in vitro].
Journal: Zhongguo shi yan xue ye xue za zhi20041001
Title: Thiol oxidation induced by oxidative action of adriamycin.
Journal: Free radical research20040901
Title: Preparation of magnetic polybutylcyanoacrylate nanospheres encapsulated with aclacinomycin A and its effect on gastric tumor.
Journal: World journal of gastroenterology20040715
Title: Assessment of the antiinvasive potential of the anthracycline aclacinomycin (Aclarubicin) in a human fibrosarcoma cell line.
Journal: International journal of oncology20040601
Title: AknK is an L-2-deoxyfucosyltransferase in the biosynthesis of the anthracycline aclacinomycin A.
Journal: Biochemistry20040420
Title: Correlation between responsiveness of neoadjuvant chemotherapy and apoptosis-associated proteins for cervical adenocarcinoma.
Journal: Gynecologic oncology20040101
Title: Activity of topoisomerase inhibitors daunorubicin, idarubicin, and aclarubicin in the Drosophila Somatic Mutation and Recombination Test.
Journal: Environmental and molecular mutagenesis20040101
Title: Neoadjuvant chemotherapy with cisplatin, aclacinomycin A, and mitomycin C for cervical adenocarcinoma--a preliminary study.
Journal: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society20040101
Title: Expression of glutathione S-transferase P1-1 in differentiating K562: role of GATA-1.
Journal: Biochemical and biophysical research communications20031128
Title: Crystal structure of aclacinomycin methylesterase with bound product analogues: implications for anthracycline recognition and mechanism.
Journal: The Journal of biological chemistry20031003
Title: Catalytic topoisomerase II inhibitors in cancer therapy.
Journal: Pharmacology & therapeutics20030801
Title: [Chemotherapy with ubenimex corresponding to patient age and organ disorder for 18 cases of acute myelogeneous leukemia in elderly patients--effects, complications and long-term survival].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20030801
Title: Morphological and biochemical changes in human fibroblast lines induced by anthracyclines during apoptosis.
Journal: Cellular & molecular biology letters20030101
Title: The nitroxides pirolin and pirolid protect the plasma membranes of rat cardiomyocytes against damage induced by anthracyclines.
Journal: Cellular & molecular biology letters20030101
Title: Comparison of anthracycline-induced death of human leukemia cells: programmed cell death versus necrosis.
Journal: Apoptosis : an international journal on programmed cell death20021201
Title: Characterization of mutations in aclacinomycin A-non-producing Streptomyces galilaeus strains with altered glycosylation patterns.
Journal: Microbiology (Reading, England)20021101
Title: Free radical production and labile iron pool decrease triggered by subtoxic concentration of aclarubicin in human leukemia cell lines.
Journal: Leukemia research20021001
Title: [WT1 gene expression in patients with acute myelogenous leukemia or high risk myelodysplastic syndrome successfully treated with the CAG regimen].
Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology20021001
Title: Nuclear transcription factor GATA-1 is activated during aclacinomycin-induced erythroid differentiation.
Journal: Biology of the cell20020901
Title: Involvement of reactive oxygen species in aclarubicin-induced differentiation and invasiveness of HL-60 leukemia cells.
Journal: International journal of oncology20020801
Title: Cloning and characterization of Streptomyces galilaeus aclacinomycins polyketide synthase (PKS) cluster.
Journal: Gene20020626
Title: Long-term follow-up of patients >or=60 yr old with acute myeloid leukaemia treated with intensive chemotherapy.
Journal: European journal of haematology20020601
Title: Antitumor effects and pharmacokinetics of aclacinomycin A carried by injectable emulsions composed of vitamin E, cholesterol, and PEG-lipid.
Journal: Journal of pharmaceutical sciences20020401
Title: Induction of p16INK4a transcription and of cellular senescence by aclacinomycin-derivatives and cardiac glycosides.
Journal: Biological & pharmaceutical bulletin20020401
Title: Modification of aklavinone and aclacinomycins in vitro and in vivo by rhodomycin biosynthesis gene products.
Journal: FEMS microbiology letters20020219
Title: Matrix and serine protease expression during leukemic cell differentiation induced by aclacinomycin and all-trans-retinoic acid.
Journal: Biochemical pharmacology20020115
Title: Superior outcome of infant acute myeloid leukemia with intensive chemotherapy: results of the Japan Infant Leukemia Study Group.
Journal: Blood20011215
Title: Linker length in podophyllotoxin-acridine conjugates determines potency in vivo and in vitro as well as specificity against MDR cell lines.
Journal: Anti-cancer drug design20011201
Title: [The cytotoxic effect of a low density lipoprotein delivered aclarubicin on leukemia cells].
Journal: Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi20011201
Title: Aclarubicin treatment restores SMN levels to cells derived from type I spinal muscular atrophy patients.
Journal: Human molecular genetics20011115
Title: [A case of breast cancer with multiple metastases effectively treated with long-term administration of docetaxel, aclarubicin and UFT].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy20011101
Title: FAB M4 and high CD14 surface expression is associated with high cellular resistance to Ara-C and daunorubicin: implications for clinical outcome in acute myeloid leukaemia.
Journal: European journal of haematology20011001
Title: Induction of urokinase-type plasminogen activator by the anthracycline antibiotic in human RC-K8 lymphoma and H69 lung-carcinoma cells.
Journal: International journal of cancer20010901
Title: Molecular cloning and disruption of a novel gene encoding UDP-glucose: tetrahydrobiopterin alpha-glucosyltransferase in the cyanobacterium Synechococcus sp. PCC 7942.
Journal: FEBS letters20010803
Title: Involvement of the NUP98 gene in a chromosomal translocation t(11;20)(p15;q11.2) in a patient with acute monocytic leukemia (FAB-M5b).
Journal: International journal of hematology20010701
Title: Myelodysplastic syndrome progresses rapidly into erythroleukemia associated with synchronous double cancers of the stomach and the papilla of Vater.
Journal: International journal of hematology20010701
Title: Recent developments in the field of antitumour anthracyclines.
Journal: European journal of medicinal chemistry20010601
Title: Pretreatment leukaemia cell drug resistance is correlated to clinical outcome in acute myeloid leukaemia.
Journal: European journal of haematology20010301
Title: The CAG regimen (low-dose cytarabine, aclarubicin hydrochloride and granulocyte colony-stimulating factor) for the treatment of elderly acute myelomonocytic leukaemia: a case study.
Journal: The Journal of international medical research20010101
Title: Modifications of aclacinomycin T by aclacinomycin methyl esterase (RdmC) and aclacinomycin-10-hydroxylase (RdmB) from Streptomyces purpurascens.
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Title: Expression and prognostic significance of IAP-family genes in human cancers and myeloid leukemias.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research20000501
Title: 1,3-Dihydroxyacridone derivatives as inhibitors of herpes virus replication.
Journal: Antiviral research20000201
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Journal: Free radical biology & medicine20000101
Title: Enhancement of chemosensitivity toward anticancer drugs by high expression of caspase-1 in NIH 3T3 cells.
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Title: Therapy-related leukemia with a novel 21q22 rearrangement.
Journal: Cancer genetics and cytogenetics19960801
Title: [Long-term selective beta 1-blockade therapy for a patient with anthracycline-induced cardiomyopathy].
Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology19951101
Title: Expression of glutathione S-transferase-pi and sensitivity of human gastric cancer cells to cisplatin.
Journal: Cancer19940815
Title: Isolation and characterization of aclacinomycin A-non-producing Streptomyces galilaeus (ATCC 31615) mutants.
Journal: Microbiology (Reading, England)19940601
Title: Structure by NMR of antitumor drugs aclacinomycin A and B complexed to d(CGTACG).
Journal: Biochemistry19940531
Title: In vitro activities of free and liposomal drugs against Mycobacterium avium-M. intracellulare complex and M. tuberculosis.
Journal: Antimicrobial agents and chemotherapy19931201
Title: Antifungal anthracycline antibiotics, spartanamicins A and B from Micromonospora spp.
Journal: The Journal of antibiotics19921101
Title: Antagonistic effect of aclarubicin on daunorubicin-induced cytotoxicity in human small cell lung cancer cells: relationship to DNA integrity and topoisomerase II.
Journal: Cancer research19911001
Title: [Torsade de pointes ventricular tachycardia in a patient with acute myelocytic leukemia].
Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology19910901
Title: New anthracycline antitumor antibiotics.
Journal: Critical reviews in oncology/hematology19910101
Title: Inhibition by doxorubicin of human immuno-deficiency virus (HIV) infection and replication in vitro.
Journal: The Journal of antibiotics19870301
Title: [Comparison of the cardiotoxicity of adriamycin and aclacinomycin A in the rat. Optical and electron microscopic study].
Journal: Archives des maladies du coeur et des vaisseaux19831101
