Title: Transient receptor potential vanilloid 1 mediates pain in mice with severe sickle cell disease.
Journal: Blood20110922
Title: Chroman and tetrahydroquinoline ureas as potent TRPV1 antagonists.
Journal: Bioorganic & medicinal chemistry letters20110301
Title: Spinal nerve ligation in mouse upregulates TRPV1 heat function in injured IB4-positive nociceptors.
Journal: The journal of pain : official journal of the American Pain Society20100601
Title: Physiological basis of tingling paresthesia evoked by hydroxy-alpha-sanshool.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20100324
Title: Moving towards supraspinal TRPV1 receptors for chronic pain relief.
Journal: Molecular pain20100101
Title: Additive antinociceptive effects of the selective Nav1.8 blocker A-803467 and selective TRPV1 antagonists in rat inflammatory and neuropathic pain models.
Journal: The journal of pain : official journal of the American Pain Society20090301
Title: Characterization of A-425619 at native TRPV1 receptors: a comparison between dorsal root ganglia and trigeminal ganglia.
Journal: European journal of pharmacology20081031
Title: Effects of the transient receptor potential vanilloid 1 antagonist A-425619 on body temperature and thermoregulation in the rat.
Journal: Neuroscience20080922
Title: TRPV1: a target for next generation analgesics.
Journal: Current neuropharmacology20080601
Title: ThermoTRP channels in nociceptors: taking a lead from capsaicin receptor TRPV1.
Journal: Current neuropharmacology20080301
Title: Identification of (R)-1-(5-tert-butyl-2,3-dihydro-1H-inden-1-yl)-3-(1H-indazol-4-yl)urea (ABT-102) as a potent TRPV1 antagonist for pain management.
Journal: Journal of medicinal chemistry20080214
Title: In vitro structure-activity relationship and in vivo characterization of 1-(aryl)-3-(4-(amino)benzyl)urea transient receptor potential vanilloid 1 antagonists.
Journal: Journal of medicinal chemistry20070726
Title: Alpha-methylation at benzylic fragment of N-aryl-N'-benzyl ureas provides TRPV1 antagonists with better pharmacokinetic properties and higher efficacy in inflammatory pain model.
Journal: Bioorganic & medicinal chemistry letters20070715
Title: The potential of transient receptor potential vanilloid type 1 channel modulators for the treatment of pain.
Journal: Journal of medicinal chemistry20070531
Title: Use of the novel Contact Heat Evoked Potential Stimulator (CHEPS) for the assessment of small fibre neuropathy: correlations with skin flare responses and intra-epidermal nerve fibre counts.
Journal: BMC neurology20070101
Title: Systemic and site-specific effects of A-425619, a selective TRPV1 receptor antagonist, on wide dynamic range neurons in CFA-treated and uninjured rats.
Journal: Journal of neurophysiology20060101
Title: A-425619 [1-isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-urea], a novel transient receptor potential type V1 receptor antagonist, relieves pathophysiological pain associated with inflammation and tissue injury in rats.
Journal: The Journal of pharmacology and experimental therapeutics20050701
Title: A-425619 [1-isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-urea], a novel and selective transient receptor potential type V1 receptor antagonist, blocks channel activation by vanilloids, heat, and acid.
Journal: The Journal of pharmacology and experimental therapeutics20050701
Title: Novel transient receptor potential vanilloid 1 receptor antagonists for the treatment of pain: structure-activity relationships for ureas with quinoline, isoquinoline, quinazoline, phthalazine, quinoxaline, and cinnoline moieties.
Journal: Journal of medicinal chemistry20050210
Title: Acidification of rat TRPV1 alters the kinetics of capsaicin responses.
Journal: Molecular pain20050101
Title: N-isoquinolin-5-yl-N'-aralkyl-urea and -amide antagonists of human vanilloid receptor 1.
Journal: Bioorganic & medicinal chemistry letters20040621
