Name: Name:2-Amino-3-oxo-3H-phenoxazine-1,9-dicarboxylic acid
Brand: AABLOCKS
SKU: AA00EF69
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA00EF69

Chemical Name: 2-Amino-3-oxo-3H-phenoxazine-1,9-dicarboxylic acid

CAS Number: 606-59-7

Molecular Formula: C14H8N2O6

Molecular Weight: 300.2231

MDL Number: MFCD18379297

SMILES: OC(=O)c1c2nc3c(oc2cc(=O)c1N)cccc3C(=O)O

Properties

Storage: Keep in dry area;2-8℃;

Complexity: 675

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 22

Hydrogen Bond Acceptor Count: 8

Hydrogen Bond Donor Count: 3

Isotope Atom Count: 0

Rotatable Bond Count: 2

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 0.8

Literature fold

Title: Cinnabarinic acid, an endogenous metabolite of the kynurenine pathway, activates type 4 metabotropic glutamate receptors.

Journal: Molecular pharmacology20120501

Title: Development of a fluorimetric detection method for cinnabarinic acid using ortho-tolyl hydrazine as the derivatization reagent.

Journal: Biomedical chromatography : BMC20100301

Title: HPLC and NMR studies of phenoxazone alkaloids from Pycnoporus cinnabarinus.

Journal: Natural product communications20090401

Title: Cinnabarinic acid generated from 3-hydroxyanthranilic acid strongly induces apoptosis in thymocytes through the generation of reactive oxygen species and the induction of caspase.

Journal: Journal of cellular biochemistry20080101

Title: F Fazio, et al. Cinnabarinic acid, an endogenous metabolite of the kynurenine pathway, activates type 4 metabotropic glutamate receptors.Mol Pharmacol. 2012 May;81(5):643-56.

Title: Martina Ulivieri, et al. The Trace Kynurenine, Cinnabarinic Acid, Displays Potent Antipsychotic-Like Activity in Mice and Its Levels Are Reduced in the Prefrontal Cortex of Individuals Affected by Schizophrenia. Schizophr Bull. 2020 Jun 7;sbaa074.

Title: Francesco Fazio, et al. Cinnabarinic acid and xanthurenic acid: Two kynurenine metabolites that interact with metabotropic glutamate receptors. Neuropharmacology. 2017 Jan;112(Pt B):365-372.

606-59-7 | 2-Amino-3-oxo-3H-phenoxazine-1,9-dicarboxylic acid