Name: Name:3-Hydroxyindolin-2-one
Brand: AABLOCKS
SKU: AA00EZ1H
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA00EZ1H

Chemical Name: 3-Hydroxyindolin-2-one

CAS Number: 61-71-2

Molecular Formula: C8H7NO2

Molecular Weight: 149.1467

MDL Number: MFCD01718285

SMILES: O=C1Nc2c(C1O)cccc2

NSC Number: 26319

Properties

Complexity: 181

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 11

Hydrogen Bond Acceptor Count: 2

Hydrogen Bond Donor Count: 2

Isotope Atom Count: 0

Rotatable Bond Count: 0

Undefined Atom Stereocenter Count: 1

Undefined Bond Stereocenter Count: 0

XLogP3: 0.2

Literature fold

Title: A facile pathway to enantiomerically enriched 3-hydroxy-2-oxindoles: asymmetric intramolecular arylation of α-keto amides catalyzed by a palladium-DifluorPhos complex.

Journal: Angewandte Chemie (International ed. in English)20110808

Title: Quinidine thiourea-catalyzed aldol reaction of unactivated ketones: highly enantioselective synthesis of 3-alkyl-3-hydroxyindolin-2-ones.

Journal: Angewandte Chemie (International ed. in English)20101203

Title: A competitive index assay identifies several Ralstonia solanacearum type III effector mutant strains with reduced fitness in host plants.

Journal: Molecular plant-microbe interactions : MPMI20100901

Title: Organocatalytic enantioselective cross-aldol reactions of aldehydes with isatins: formation of two contiguous quaternary centered 3-substituted 3-hydroxyindol-2-ones.

Journal: Chemistry, an Asian journal20091102

Title: Biological targets for isatin and its analogues: Implications for therapy.

Journal: Biologics : targets & therapy20070601

Title: Synthesis of 3-substituted-2-oxoindole analogues and their evaluation as kinase inhibitors, anticancer and antiangiogenic agents.

Journal: European journal of medicinal chemistry20060301

Title: Characterization of a major form of human isatin reductase and the reduced metabolite.

Journal: European journal of biochemistry20011101

Title: Studies on the biosynthesis of 2-hydroxy-1,4-benzoxazin-3-one (HBOA) from 3-hydroxyindolin-2-one in Zea mays.

Journal: Phytochemistry20010601

61-71-2 | 3-Hydroxyindolin-2-one