620-08-6 | 4-Methoxypyridine

Title: Ru complexes containing pyridine dicarboxylate ligands: electronic effects on their catalytic activity toward water oxidation.

Journal: Faraday discussions 20120101

Title: Adsorption behavior of 4-methoxypyridine on gold nanoparticles.

Journal: Langmuir : the ACS journal of surfaces and colloids 20110607

Title: Diazotization of the amino acid [closo-1-CB9H8-1-COOH-6-NH3] and reactivity of the [closo-1-CB9H8-1-COO-6-N2]- anion.

Journal: Inorganic chemistry 20110321

Title: Synthesis of 4-pyridone-3-sulfate and an improved synthesis of 3-hydroxy-4-pyridone.

Journal: Chemistry Central journal 20090101

Title: Structurally-defined potassium-mediated regioselective zincation of amino- and alkoxy-substituted pyridines.

Journal: Chemical communications (Cambridge, England) 20080621

Title: Probing lead(II) bonding environments in 4-substituted pyridine adducts of (2,6-Me2C6H3S)2Pb: an X-ray structural and solid-state 207Pb NMR study.

Journal: Inorganic chemistry 20071015

Title: Synthesis of the benzo-fused indolizidine alkaloid mimics.

Journal: Beilstein journal of organic chemistry 20070101

Title: Donor-acceptor interactions and electron transfer in cyano-bridged trinuclear compounds.

Journal: Inorganic chemistry 20061225

Title: Stereoselective synthesis of pyridinones: application to the synthesis of (-)-barrenazines.

Journal: Organic letters 20060706

Title: Synthesis and kinetic analysis of the N-acetylhexosaminidase inhibitor XylNAc-isofagomine.

Journal: The Journal of organic chemistry 20050916

Title: Formation of hypervalent complexes of trifluorosilanes with pyridine and with 4-methoxypyridine, through intermolecular silicon...nitrogen interactions.

Journal: Inorganic chemistry 20050221

Title: Fine tuning of the electronic coupling between metal centers in cyano-bridged mixed-valent trinuclear complexes.

Journal: Inorganic chemistry 20041018

Title: Synthesis of bridged azabicyclic structures via ring-closing olefin metathesis.

Journal: The Journal of organic chemistry 20031114

Title: Toxic seizures in children: case scenarios and treatment strategies.

Journal: Pediatric emergency care 20030601

Title: Pyrido[2,1-f]purine-2,4-dione derivatives as a novel class of highly potent human A(3) adenosine receptor antagonists.

Journal: Journal of medicinal chemistry 20020801

Title: Total synthesis of the putative structure of the lupin alkaloid plumerinine.

Journal: Organic letters 20020502

Title: Stereoselective total syntheses and reassignment of stereochemistry of the freshwater cyanobacterial hepatotoxins cylindrospermopsin and 7-epicylindrospermopsin.

Journal: Journal of the American Chemical Society 20020417

4-Methoxypyridine is a chemical compound with diverse applications in organic synthesis and medicinal chemistry. Its strategic role as a starting material facilitates the synthesis of various biologically active molecules with significant pharmaceutical potential.

In organic synthesis, 4-methoxypyridine serves as a key building block for the stereocontrolled synthesis of complex natural products such as (±)-pumiliotoxin C and (±)-lasubine II. These compounds are known for their intriguing molecular structures and potential pharmacological activities, making them valuable targets for synthetic chemists and medicinal researchers.

Additionally, 4-methoxypyridine plays a crucial role in the efficient construction of dihydropyridin-4-ones. These heterocyclic compounds serve as promising ligands for neuronal nicotinic acetylcholine receptors, which are implicated in various physiological processes and neurological disorders. By serving as a precursor in the synthesis of these compounds, 4-methoxypyridine contributes to the development of novel ligands with potential applications in neuroscience research and drug discovery.

Overall, 4-methoxypyridine is a versatile compound that enables the synthesis of structurally diverse molecules with potential pharmaceutical relevance. Its use as a starting material underscores its importance in organic synthesis and medicinal chemistry, highlighting its utility in the pursuit of new therapeutic agents and molecular probes.