64165-64-6,MFCD00056728
Catalog No.:AA00JKG1

64165-64-6 | DL-Propargylglycine

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
≥ 98%
in stock  
$197.00   $138.00
- +
5g
≥ 98%
in stock  
$670.00   $469.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00JKG1
Chemical Name:
DL-Propargylglycine
CAS Number:
64165-64-6
Molecular Formula:
C5H7NO2
Molecular Weight:
113.1146
MDL Number:
MFCD00056728
SMILES:
C#CCC(C(=O)O)N
NSC Number:
21940
Properties
Computed Properties
 
Complexity:
133  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
8  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0  
Rotatable Bond Count:
2  
Undefined Atom Stereocenter Count:
1  
Undefined Bond Stereocenter Count:
0  
XLogP3:
-2.8  

Literature

Title: Placental Stem Villus Arterial Remodeling Associated with Reduced Hydrogen Sulfide Synthesis Contributes to Human Fetal Growth Restriction.

Journal: The American journal of pathology 20170401

Title: Selectivity of commonly used pharmacological inhibitors for cystathionine β synthase (CBS) and cystathionine γ lyase (CSE).

Journal: British journal of pharmacology 20130601

Title: The role of endogenous hydrogen sulfide in pathogenesis of chronotropic dysfunction in rats with cirrhosis.

Journal: European journal of pharmacology 20121205

Title: Endogenous H2S is required for hypoxic sensing by carotid body glomus cells.

Journal: American journal of physiology. Cell physiology 20121101

Title: Role of KATP channels and TRPV1 receptors in hydrogen sulfide-enhanced gastric emptying of liquid in awake mice.

Journal: European journal of pharmacology 20121015

Title: Synthesis of multivalent neoglyconjugates of MUC1 by the conjugation of carbohydrate-centered, triazole-linked glycoclusters to MUC1 peptides using click chemistry.

Journal: The Journal of organic chemistry 20120907

Title: Arecoline improves vascular endothelial function in high fructose-fed rats via increasing cystathionine-γ-lyase expression and activating K(ATP) channels.

Journal: Acta pharmacologica Sinica 20120801

Title: Combating the drug resistance of cisplatin using a platinum prodrug based delivery system.

Journal: Angewandte Chemie (International ed. in English) 20120702

Title: Inhibition of cystathionine gamma-lyase and the biosynthesis of endogenous hydrogen sulphide ameliorates gentamicin-induced nephrotoxicity.

Journal: European journal of pharmacology 20120615

Title: Tuning the properties of elastin mimetic hybrid copolymers via a modular polymerization method.

Journal: Biomacromolecules 20120611

Title: Gastroprotective effect of NaHS against mucosal lesions induced by ischemia-reperfusion injury in rat.

Journal: Digestive diseases and sciences 20120601

Title: Effect of hydrogen sulfide on restenosis of peripheral arteries after angioplasty.

Journal: Molecular medicine reports 20120601

Title: Role of endogenous hydrogen sulfide in neurogenic relaxation of rat corpus cavernosum.

Journal: Biochemical pharmacology 20120501

Title: Mechanism of action of hydrogen sulfide on cyclic AMP formation in rat retinal pigment epithelial cells.

Journal: Experimental eye research 20120501

Title: Influence of an unnatural amino acid side chain on the conformational dynamics of peptides.

Journal: Chemphyschem : a European journal of chemical physics and physical chemistry 20120423

Title: Transplant tolerance is associated with reduced expression of cystathionine-γ-lyase that controls IL-12 production by dendritic cells and TH-1 immune responses.

Journal: Blood 20120315

Title: Effect of endogenous hydrogen sulfide inhibition on structural and functional renal disturbances induced by gentamicin.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20120301

Title: Precursors and inhibitors of hydrogen sulfide synthesis affect acute hypoxic pulmonary vasoconstriction in the intact lung.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20120201

Title: Biologically active polymersomes from amphiphilic glycopeptides.

Journal: Journal of the American Chemical Society 20120111

Title: Interdependency of cystathione γ-lyase and cystathione β-synthase in hydrogen sulfide-induced blood pressure regulation in rats.

Journal: American journal of hypertension 20120101

Title: Gas mediators involved in modulating duodenal HCO3(-) secretion.

Journal: Current medicinal chemistry 20120101

Title: Modulation of ion transport across rat distal colon by cysteine.

Journal: Frontiers in physiology 20120101

Title: TRPA1 has a key role in the somatic pro-nociceptive actions of hydrogen sulfide.

Journal: PloS one 20120101

Title: Evidence that endogenous hydrogen sulfide exerts an excitatory effect on gastric motility in mice.

Journal: European journal of pharmacology 20111230

Title: Role of endogenous hydrogen sulfide on renal damage induced by adriamycin injection.

Journal: Archives of toxicology 20111201

Title: Hydrogen sulfide and L-cysteine increase phosphatidylinositol 3,4,5-trisphosphate (PIP3) and glucose utilization by inhibiting phosphatase and tensin homolog (PTEN) protein and activating phosphoinositide 3-kinase (PI3K)/serine/threonine protein kinase (AKT)/protein kinase Cζ/λ (PKCζ/λ) in 3T3l1 adipocytes.

Journal: The Journal of biological chemistry 20111118

Title: Hydrogen sulfide regulates vascular endoplasmic reticulum stress in apolipoprotein E knockout mice.

Journal: Chinese medical journal 20111101

Title: The protective role of hydrogen sulfide in myocardial ischemia-reperfusion-induced injury in diabetic rats.

Journal: International journal of cardiology 20111020

Title: Effects of inhibitors of hydrogen sulphide synthesis on rat colonic motility.

Journal: British journal of pharmacology 20110901

Title: Endogenous production of hydrogen sulfide in isolated bovine eye.

Journal: Neurochemical research 20110801

Title: Triostin A derived hybrid for simultaneous DNA binding and metal coordination.

Journal: Amino acids 20110701

Title: Cellular mechanisms underlying Hyperin-induced relaxation of rat basilar artery.

Journal: Fitoterapia 20110601

Title: S-Propargyl-cysteine (SPRC) attenuated lipopolysaccharide-induced inflammatory response in H9c2 cells involved in a hydrogen sulfide-dependent mechanism.

Journal: Amino acids 20110601

Title: Endogenous hydrogen sulfide is an anti-inflammatory molecule in dextran sodium sulfate-induced colitis in mice.

Journal: Digestive diseases and sciences 20110501

Title: Mechanism of vasorelaxation and role of endogenous hydrogen sulfide production in mouse aorta.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20110401

Title: Involvement of endogenous hydrogen sulfide in cigarette smoke-induced changes in airway responsiveness and inflammation of rat lung.

Journal: Cytokine 20110301

Title: Genome-scale metabolic modeling elucidates the role of proliferative adaptation in causing the Warburg effect.

Journal: PLoS computational biology 20110301

Title: Synthesis and cytotoxicity of a bimetallic ruthenocene dicobalt-hexacarbonyl alkyne peptide bioconjugate.

Journal: Dalton transactions (Cambridge, England : 2003) 20110214

Title: Inhibition of hydrogen sulphide formation reduces cisplatin-induced renal damage.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20110201

Title: Hydrogen sulfide inhibits macrophage-derived foam cell formation.

Journal: Experimental biology and medicine (Maywood, N.J.) 20110201

Title: Stimulation of duodenal HCO₃⁻ secretion by hydrogen sulphide in rats: relation to prostaglandins, nitric oxide and sensory neurones.

Journal: Acta physiologica (Oxford, England) 20110101

Title: Role of glutathione in immunity and inflammation in the lung.

Journal: International journal of general medicine 20110101

Title: Conformationally constrained histidines in the design of peptidomimetics: strategies for the χ-space control.

Journal: International journal of molecular sciences 20110101

Title: H2S donor, S-propargyl-cysteine, increases CSE in SGC-7901 and cancer-induced mice: evidence for a novel anti-cancer effect of endogenous H2S?

Journal: PloS one 20110101

Title: Bacterial Catabolism of Dimethylsulfoniopropionate (DMSP).

Journal: Frontiers in microbiology 20110101

Title: Protective role of hydrogen sulfide against noise-induced cochlear damage: a chronic intracochlear infusion model.

Journal: PloS one 20110101

Title: Sulfated-polysaccharide fraction from red algae Gracilaria caudata protects mice gut against ethanol-induced damage.

Journal: Marine drugs 20110101

Title: Preparation and preliminary bioevaluation of 99mTc(CO)3-11β-progesterone derivative prepared via click chemistry route.

Journal: Nuclear medicine and biology 20101101

Title: Hydrogen sulfide is an endogenous inhibitor of phosphodiesterase activity.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20101001

Title: Cystathionine beta-synthase null homocystinuric mice fail to exhibit altered hemostasis or lowering of plasma homocysteine in response to betaine treatment.

Journal: Molecular genetics and metabolism 20101001

Title: Aza-1,2,3-triazole-3-alanine synthesis via copper-catalyzed 1,3-dipolar cycloaddition on aza-progargylglycine.

Journal: The Journal of organic chemistry 20100806

Title: A crucial role for hydrogen sulfide in oxygen sensing via modulating large conductance calcium-activated potassium channels.

Journal: Antioxidants & redox signaling 20100515

Title: Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H(2)S production.

Journal: Antioxidants & redox signaling 20100515

Title: Vasoactivity of hydrogen sulfide in normoxic and anoxic turtles (Trachemys scripta).

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20100501

Title: Differing effects of exogenous and endogenous hydrogen sulphide in carrageenan-induced knee joint synovitis in the rat.

Journal: British journal of pharmacology 20100401

Title: Inhibition of endogenous hydrogen sulfide synthesis by PAG protects against ethanol-induced gastric damage in the rat.

Journal: European journal of pharmacology 20100325

Title: Glutathione depletion causes a JNK and p38MAPK-mediated increase in expression of cystathionine-gamma-lyase and upregulation of the transsulfuration pathway in C6 glioma cells.

Journal: Neurochemistry international 20100301

Title: L-cysteine stimulates hydrogen sulfide synthesis in myocardium associated with attenuation of ischemia-reperfusion injury.

Journal: Journal of cardiovascular pharmacology and therapeutics 20100301

Title: Hydrogen sulfide promotes transient receptor potential vanilloid 1-mediated neurogenic inflammation in polymicrobial sepsis.

Journal: Critical care medicine 20100201

Title: The structure of the proline utilization a proline dehydrogenase domain inactivated by N-propargylglycine provides insight into conformational changes induced by substrate binding and flavin reduction.

Journal: Biochemistry 20100126

Title: Role of hydrogen sulfide in severe burn injury-induced inflammation in mice.

Journal: Molecular medicine (Cambridge, Mass.) 20100101

Title: Cysteinyl-glycine in the control of glutathione homeostasis in bovine lenses.

Journal: Molecular vision 20100101

Title: Hydrogen sulfide induces apoptosis of pulmonary artery smooth muscle cell in rats with pulmonary hypertension induced by high pulmonary blood flow.

Journal: Chinese medical journal 20091220

Title: Thermal melting studies of alkyne- and ferrocene-containing PNA bioconjugates.

Journal: Organic & biomolecular chemistry 20091207

Title: Regulation of [3H] D-aspartate release from mammalian isolated retinae by hydrogen sulfide.

Journal: Neurochemical research 20091101

Title: Application of copper(I) catalyzed azide-alkyne [3+2] cycloaddition to the synthesis of template-assembled multivalent peptide conjugates.

Journal: Organic & biomolecular chemistry 20091021

Title: Astrocytes produce the antiinflammatory and neuroprotective agent hydrogen sulfide.

Journal: Neurobiology of aging 20091001

Title: Extracellular redox modulation by regulatory T cells.

Journal: Nature chemical biology 20091001

Title: Hydrogen sulfide prevents ethanol-induced gastric damage in mice: role of ATP-sensitive potassium channels and capsaicin-sensitive primary afferent neurons.

Journal: The Journal of pharmacology and experimental therapeutics 20090901

Title: S-propargyl-cysteine protects both adult rat hearts and neonatal cardiomyocytes from ischemia/hypoxia injury: the contribution of the hydrogen sulfide-mediated pathway.

Journal: Journal of cardiovascular pharmacology 20090801

Title: Cardioprotective effect of hydrogen sulfide in ischemic reperfusion experimental rats and its influence on expression of survivin gene.

Journal: Biological & pharmaceutical bulletin 20090801

Title: Efficient screening for new amino acid dehydrogenase activity: directed evolution of Bacillus sphaericus phenylalanine dehydrogenase towards activity with an unsaturated non-natural amino acid.

Journal: Journal of biotechnology 20090615

Title: Hydrogen sulfide as a novel mediator for pancreatic pain in rodents.

Journal: Gut 20090601

Title: Production and actions of hydrogen sulfide, a novel gaseous bioactive substance, in the kidneys.

Journal: The Journal of pharmacology and experimental therapeutics 20090601

Title: Endogenous hydrogen sulfide regulates pulmonary artery collagen remodeling in rats with high pulmonary blood flow.

Journal: Experimental biology and medicine (Maywood, N.J.) 20090501

Title: Synthesis and characterization of dicobalthexacarbonyl-alkyne derivatives of amino acids, peptides, and peptide nucleic acid (PNA) monomers.

Journal: Inorganic chemistry 20090406

Title: [Role of hydrogen sulfide/cystathionine-gamma-lyase system in acute lung injury induced by lipopolysaccharide in rats].

Journal: Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20090401

Title: Synthesis and aromatisation of cyclic enediyne-containing amino acids.

Journal: Organic & biomolecular chemistry 20090221

Title: Role of hydrogen sulfide in the development of atherosclerotic lesions in apolipoprotein E knockout mice.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20090201

Title: Pancreatic islet overproduction of H2S and suppressed insulin release in Zucker diabetic rats.

Journal: Laboratory investigation; a journal of technical methods and pathology 20090101

Title: Down-regulation of endogenous hydrogen sulphide pathway in nasal mucosa of allergic rhinitis in guinea pigs.

Journal: Allergologia et immunopathologia 20090101

Title: DYRK1A, a novel determinant of the methionine-homocysteine cycle in different mouse models overexpressing this Down-syndrome-associated kinase.

Journal: PloS one 20090101

Title: Inhibitory action of hydrogen sulfide on muscarinic receptor-induced contraction of isolated porcine irides.

Journal: Experimental eye research 20081201

Title: H2S contributes to the hepatic arterial buffer response and mediates vasorelaxation of the hepatic artery via activation of K(ATP) channels.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20081201

Title: Novel glycated [99mTc(CO)3]-labeled bombesin analogues for improved targeting of gastrin-releasing peptide receptor-positive tumors.

Journal: Bioconjugate chemistry 20081201

Title: Tags for labeling protein N-termini with subtiligase for proteomics.

Journal: Bioorganic & medicinal chemistry letters 20081115

Title: Expanding the genetic code of Saccharomyces cerevisiae with methionine analogues.

Journal: Yeast (Chichester, England) 20081101

Title: Hydrogen sulphide is pro-inflammatory in haemorrhagic shock.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20081101

Title: Convenient syntheses of homopropargylglycine.

Journal: Journal of peptide science : an official publication of the European Peptide Society 20081001

Title: Endogenous hydrogen sulphide mediates the cardioprotection induced by ischemic postconditioning.

Journal: American journal of physiology. Heart and circulatory physiology 20080901

Title: [Effects of hydrogen sulfide on vascular inflammation in pulmonary hypertension induced by high pulmonary blood flow: experiment with rats].

Journal: Zhonghua yi xue za zhi 20080819

Title: Synthesis and conformational analysis of a cyclic peptide obtained via i to i+4 intramolecular side-chain to side-chain azide-alkyne 1,3-dipolar cycloaddition.

Journal: The Journal of organic chemistry 20080801

Title: The role of cysteine 116 in the active site of the antitumor enzyme L-methionine gamma-lyase from Pseudomonas putida.

Journal: Bioscience, biotechnology, and biochemistry 20080701

Title: [The role of hydrogen sulfide and cystathionine-gamma-lyase in allergic rhinitis guinea pigs].

Journal: Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery 20080701

Title: Ribosomal synthesis of bicyclic peptides via two orthogonal inter-side-chain reactions.

Journal: Journal of the American Chemical Society 20080611

Title: Hydrogen sulfide protects rat lung from ischemia-reperfusion injury.

Journal: Life sciences 20080606

Title: [Hypotensive effects of hydrogen sulfide via attenuating vascular inflammation in spontaneously hypertensive rats].

Journal: Zhonghua xin xue guan bing za zhi 20080601

Title: Structural basis for the inactivation of Thermus thermophilus proline dehydrogenase by N-propargylglycine.

Journal: Biochemistry 20080520

Title: Inhibition of hydrogen sulfide synthesis attenuates chemokine production and protects mice against acute pancreatitis and associated lung injury.

Journal: Pancreas 20080501

Title: Pro-inflammatory effects of hydrogen sulphide on substance P in caerulein-induced acute pancreatitis.

Journal: Journal of cellular and molecular medicine 20080401

Title: A nociceptive-intensity-dependent role for hydrogen sulphide in the formalin model of persistent inflammatory pain.

Journal: Neuroscience 20080303

Title: Endogenous hydrogen sulfide regulates leukocyte trafficking in cecal ligation and puncture-induced sepsis.

Journal: Journal of leukocyte biology 20071001

Title: The regulatory effect of endogenous hydrogen sulfide on pulmonary vascular structure and gasotransmitters in rats with high pulmonary blood flow.

Journal: Life sciences 20070816

Title: Hydrogen sulfide facilitates carotid sinus baroreceptor activity in anesthetized male rats.

Journal: Chinese medical journal 20070805

Title: Activation of apoptosis signal regulating kinase 1 (ASK1) and translocation of death-associated protein, Daxx, in substantia nigra pars compacta in a mouse model of Parkinson's disease: protection by alpha-lipoic acid.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070701

Title: [Relationship between hydrogen sulfide and myocardial damage in endotoxemic rats].

Journal: Sheng li xue bao : [Acta physiologica Sinica] 20070625

Title: Hydrogen sulfide acts as an inflammatory mediator in cecal ligation and puncture-induced sepsis in mice by upregulating the production of cytokines and chemokines via NF-kappaB.

Journal: American journal of physiology. Lung cellular and molecular physiology 20070401

Title: Hydrogen sulfide and its possible roles in myocardial ischemia in experimental rats.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20070101

Title: Monocyte differentiation, activation, and mycobacterial killing are linked to transsulfuration-dependent redox metabolism.

Journal: The Journal of biological chemistry 20061215

Title: Interaction between hydrogen sulfide/cystathionine gamma-lyase and carbon monoxide/heme oxygenase pathways in aortic smooth muscle cells.

Journal: Acta pharmacologica Sinica 20061201

Title: Hydrogen sulfide is a novel prosecretory neuromodulator in the Guinea-pig and human colon.

Journal: Gastroenterology 20061101

Title: Cysteine biosynthesis in Trichomonas vaginalis involves cysteine synthase utilizing O-phosphoserine.

Journal: The Journal of biological chemistry 20060901

Title: The production of hydrogen sulfide limits myocardial ischemia and reperfusion injury and contributes to the cardioprotective effects of preconditioning with endotoxin, but not ischemia in the rat.

Journal: Shock (Augusta, Ga.) 20060801

Title: Role of hydrogen sulfide in cecal ligation and puncture-induced sepsis in the mouse.

Journal: American journal of physiology. Lung cellular and molecular physiology 20060601

Title: [Impact of hydrogen sulfide, a novel gaseous signal molecule on nitric oxide/nitric oxide synthase pathway in left-to-right shunt: experiment with rats].

Journal: Zhonghua yi xue za zhi 20060523

Title: Possible role for the novel gasotransmitter hydrogen sulphide in erectile dysfunction--a pilot study.

Journal: European journal of pharmacology 20060327

Title: Hydrogen sulfide facilitates carotid sinus baroreflex in anesthetized rats.

Journal: Acta pharmacologica Sinica 20060301

Title: Cystathionine gamma-lyase contributes to selenomethionine detoxification and cytosolic glutathione peroxidase biosynthesis in mouse liver.

Journal: Biological trace element research 20060201

Title: Endogenous hydrogen sulfide contributes to the cardioprotection by metabolic inhibition preconditioning in the rat ventricular myocytes.

Journal: Journal of molecular and cellular cardiology 20060101

Title: D-amino-acid oxidase is involved in D-serine-induced nephrotoxicity.

Journal: Chemical research in toxicology 20051101

Title: Inhibition of endogenous hydrogen sulfide formation reduces the organ injury caused by endotoxemia.

Journal: British journal of pharmacology 20051001

Title: Hydrogen sulfide is a novel mediator of lipopolysaccharide-induced inflammation in the mouse.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050701

Title: Hydrogen sulphide is a mediator of carrageenan-induced hindpaw oedema in the rat.

Journal: British journal of pharmacology 20050501

Title: Role of hydrogen sulfide in acute pancreatitis and associated lung injury.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050401

Title: Functional demonstration of reverse transsulfuration in the Mycobacterium tuberculosis complex reveals that methionine is the preferred sulfur source for pathogenic Mycobacteria.

Journal: The Journal of biological chemistry 20050304

Title: Age-associated oxidative damage leads to absence of gamma-cystathionase in over 50% of rat lenses: relevance in cataractogenesis.

Journal: Free radical biology & medicine 20050301

Title: Hydrogen sulfide as an endogenous modulator of biliary bicarbonate excretion in the rat liver.

Journal: Antioxidants & redox signaling 20050101

Title: Role of hydrogen sulphide in haemorrhagic shock in the rat: protective effect of inhibitors of hydrogen sulphide biosynthesis.

Journal: British journal of pharmacology 20041201

Title: The presence of a transsulfuration pathway in the lens: a new oxidative stress defense system.

Journal: Experimental eye research 20041201

Title: A chemoenzymatic approach to glycopeptide antibiotics.

Journal: Journal of the American Chemical Society 20041103

Title: Aviglycine and propargylglycine inhibit conidial germination and mycelial growth of Fusarium oxysporumf. sp. luffae.

Journal: Mycopathologia 20041001

Title: [The regulation of carbon monoxide/heme oxygenase system by hydrogen sulfide in rats with hypoxic pulmonary hypertension].

Journal: Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20041001

Title: Reversal of acquired cisplatin resistance by modulation of metallothionein in transplanted murine tumors.

Journal: International journal of urology : official journal of the Japanese Urological Association 20040601

Title: Impact of hydrogen sulfide on carbon monoxide/heme oxygenase pathway in the pathogenesis of hypoxic pulmonary hypertension.

Journal: Biochemical and biophysical research communications 20040423

Title: The possible role of hydrogen sulfide on the pathogenesis of spontaneous hypertension in rats.

Journal: Biochemical and biophysical research communications 20040102

Title: Modulation of endogenous production of H2S in rat tissues.

Journal: Canadian journal of physiology and pharmacology 20030901

Title: Inhibition of liver trans-sulphuration pathway by propargylglycine mimics gene expression changes found in the mammary gland of weaned lactating rats: role of glutathione.

Journal: The Biochemical journal 20030801

Title: Effect of acute betaine administration on hepatic metabolism of S-amino acids in rats and mice.

Journal: Biochemical pharmacology 20030501

Title: The smooth muscle relaxant effect of hydrogen sulphide in vitro: evidence for a physiological role to control intestinal contractility.

Journal: British journal of pharmacology 20020901

Title: Structure of external aldimine of Escherichia coli CsdB, an IscS/NifS homolog: implications for its specificity toward selenocysteine.

Journal: Journal of biochemistry 20020501

Title: Cystathionine pathway-dependent cytotoxicities of diethyl maleate and diamide in rat and human hepatoma-derived cell cultures.

Journal: Alternatives to laboratory animals : ATLA 20020101

Title: Cysteine regulates expression of cysteine dioxygenase and gamma-glutamylcysteine synthetase in cultured rat hepatocytes.

Journal: American journal of physiology. Endocrinology and metabolism 20010501

Title: Development of new carboxylic acid-based MMP inhibitors derived from functionalized propargylglycines.

Journal: Journal of medicinal chemistry 20010329

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Related Products of 64165-64-6
Tags:64165-64-6 Molecular Formula|64165-64-6 MDL|64165-64-6 SMILES|64165-64-6 DL-Propargylglycine
Catalog No.: AA00JKG1
64165-64-6,MFCD00056728
64165-64-6 | DL-Propargylglycine
Pack Size: 1g
Purity: ≥ 98%
in stock
$197.00 $138.00
Pack Size: 5g
Purity: ≥ 98%
in stock
$670.00 $469.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA00JKG1
Chemical Name: DL-Propargylglycine
CAS Number: 64165-64-6
Molecular Formula: C5H7NO2
Molecular Weight: 113.1146
MDL Number: MFCD00056728
SMILES: C#CCC(C(=O)O)N
NSC Number: 21940
Properties
Complexity: 133  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 8  
Hydrogen Bond Acceptor Count: 3  
Hydrogen Bond Donor Count: 2  
Isotope Atom Count: 0  
Rotatable Bond Count: 2  
Undefined Atom Stereocenter Count: 1  
Undefined Bond Stereocenter Count: 0  
XLogP3: -2.8  
Literature fold

Title: Placental Stem Villus Arterial Remodeling Associated with Reduced Hydrogen Sulfide Synthesis Contributes to Human Fetal Growth Restriction.

Journal: The American journal of pathology20170401

Title: Selectivity of commonly used pharmacological inhibitors for cystathionine β synthase (CBS) and cystathionine γ lyase (CSE).

Journal: British journal of pharmacology20130601

Title: The role of endogenous hydrogen sulfide in pathogenesis of chronotropic dysfunction in rats with cirrhosis.

Journal: European journal of pharmacology20121205

Title: Endogenous H2S is required for hypoxic sensing by carotid body glomus cells.

Journal: American journal of physiology. Cell physiology20121101

Title: Role of KATP channels and TRPV1 receptors in hydrogen sulfide-enhanced gastric emptying of liquid in awake mice.

Journal: European journal of pharmacology20121015

Title: Synthesis of multivalent neoglyconjugates of MUC1 by the conjugation of carbohydrate-centered, triazole-linked glycoclusters to MUC1 peptides using click chemistry.

Journal: The Journal of organic chemistry20120907

Title: Arecoline improves vascular endothelial function in high fructose-fed rats via increasing cystathionine-γ-lyase expression and activating K(ATP) channels.

Journal: Acta pharmacologica Sinica20120801

Title: Combating the drug resistance of cisplatin using a platinum prodrug based delivery system.

Journal: Angewandte Chemie (International ed. in English)20120702

Title: Inhibition of cystathionine gamma-lyase and the biosynthesis of endogenous hydrogen sulphide ameliorates gentamicin-induced nephrotoxicity.

Journal: European journal of pharmacology20120615

Title: Tuning the properties of elastin mimetic hybrid copolymers via a modular polymerization method.

Journal: Biomacromolecules20120611

Title: Gastroprotective effect of NaHS against mucosal lesions induced by ischemia-reperfusion injury in rat.

Journal: Digestive diseases and sciences20120601

Title: Effect of hydrogen sulfide on restenosis of peripheral arteries after angioplasty.

Journal: Molecular medicine reports20120601

Title: Role of endogenous hydrogen sulfide in neurogenic relaxation of rat corpus cavernosum.

Journal: Biochemical pharmacology20120501

Title: Mechanism of action of hydrogen sulfide on cyclic AMP formation in rat retinal pigment epithelial cells.

Journal: Experimental eye research20120501

Title: Influence of an unnatural amino acid side chain on the conformational dynamics of peptides.

Journal: Chemphyschem : a European journal of chemical physics and physical chemistry20120423

Title: Transplant tolerance is associated with reduced expression of cystathionine-γ-lyase that controls IL-12 production by dendritic cells and TH-1 immune responses.

Journal: Blood20120315

Title: Effect of endogenous hydrogen sulfide inhibition on structural and functional renal disturbances induced by gentamicin.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas20120301

Title: Precursors and inhibitors of hydrogen sulfide synthesis affect acute hypoxic pulmonary vasoconstriction in the intact lung.

Journal: Journal of applied physiology (Bethesda, Md. : 1985)20120201

Title: Biologically active polymersomes from amphiphilic glycopeptides.

Journal: Journal of the American Chemical Society20120111

Title: Interdependency of cystathione γ-lyase and cystathione β-synthase in hydrogen sulfide-induced blood pressure regulation in rats.

Journal: American journal of hypertension20120101

Title: Gas mediators involved in modulating duodenal HCO3(-) secretion.

Journal: Current medicinal chemistry20120101

Title: Modulation of ion transport across rat distal colon by cysteine.

Journal: Frontiers in physiology20120101

Title: TRPA1 has a key role in the somatic pro-nociceptive actions of hydrogen sulfide.

Journal: PloS one20120101

Title: Evidence that endogenous hydrogen sulfide exerts an excitatory effect on gastric motility in mice.

Journal: European journal of pharmacology20111230

Title: Role of endogenous hydrogen sulfide on renal damage induced by adriamycin injection.

Journal: Archives of toxicology20111201

Title: Hydrogen sulfide and L-cysteine increase phosphatidylinositol 3,4,5-trisphosphate (PIP3) and glucose utilization by inhibiting phosphatase and tensin homolog (PTEN) protein and activating phosphoinositide 3-kinase (PI3K)/serine/threonine protein kinase (AKT)/protein kinase Cζ/λ (PKCζ/λ) in 3T3l1 adipocytes.

Journal: The Journal of biological chemistry20111118

Title: Hydrogen sulfide regulates vascular endoplasmic reticulum stress in apolipoprotein E knockout mice.

Journal: Chinese medical journal20111101

Title: The protective role of hydrogen sulfide in myocardial ischemia-reperfusion-induced injury in diabetic rats.

Journal: International journal of cardiology20111020

Title: Effects of inhibitors of hydrogen sulphide synthesis on rat colonic motility.

Journal: British journal of pharmacology20110901

Title: Endogenous production of hydrogen sulfide in isolated bovine eye.

Journal: Neurochemical research20110801

Title: Triostin A derived hybrid for simultaneous DNA binding and metal coordination.

Journal: Amino acids20110701

Title: Cellular mechanisms underlying Hyperin-induced relaxation of rat basilar artery.

Journal: Fitoterapia20110601

Title: S-Propargyl-cysteine (SPRC) attenuated lipopolysaccharide-induced inflammatory response in H9c2 cells involved in a hydrogen sulfide-dependent mechanism.

Journal: Amino acids20110601

Title: Endogenous hydrogen sulfide is an anti-inflammatory molecule in dextran sodium sulfate-induced colitis in mice.

Journal: Digestive diseases and sciences20110501

Title: Mechanism of vasorelaxation and role of endogenous hydrogen sulfide production in mouse aorta.

Journal: Naunyn-Schmiedeberg's archives of pharmacology20110401

Title: Involvement of endogenous hydrogen sulfide in cigarette smoke-induced changes in airway responsiveness and inflammation of rat lung.

Journal: Cytokine20110301

Title: Genome-scale metabolic modeling elucidates the role of proliferative adaptation in causing the Warburg effect.

Journal: PLoS computational biology20110301

Title: Synthesis and cytotoxicity of a bimetallic ruthenocene dicobalt-hexacarbonyl alkyne peptide bioconjugate.

Journal: Dalton transactions (Cambridge, England : 2003)20110214

Title: Inhibition of hydrogen sulphide formation reduces cisplatin-induced renal damage.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association20110201

Title: Hydrogen sulfide inhibits macrophage-derived foam cell formation.

Journal: Experimental biology and medicine (Maywood, N.J.)20110201

Title: Stimulation of duodenal HCO₃⁻ secretion by hydrogen sulphide in rats: relation to prostaglandins, nitric oxide and sensory neurones.

Journal: Acta physiologica (Oxford, England)20110101

Title: Role of glutathione in immunity and inflammation in the lung.

Journal: International journal of general medicine20110101

Title: Conformationally constrained histidines in the design of peptidomimetics: strategies for the χ-space control.

Journal: International journal of molecular sciences20110101

Title: H2S donor, S-propargyl-cysteine, increases CSE in SGC-7901 and cancer-induced mice: evidence for a novel anti-cancer effect of endogenous H2S?

Journal: PloS one20110101

Title: Bacterial Catabolism of Dimethylsulfoniopropionate (DMSP).

Journal: Frontiers in microbiology20110101

Title: Protective role of hydrogen sulfide against noise-induced cochlear damage: a chronic intracochlear infusion model.

Journal: PloS one20110101

Title: Sulfated-polysaccharide fraction from red algae Gracilaria caudata protects mice gut against ethanol-induced damage.

Journal: Marine drugs20110101

Title: Preparation and preliminary bioevaluation of 99mTc(CO)3-11β-progesterone derivative prepared via click chemistry route.

Journal: Nuclear medicine and biology20101101

Title: Hydrogen sulfide is an endogenous inhibitor of phosphodiesterase activity.

Journal: Arteriosclerosis, thrombosis, and vascular biology20101001

Title: Cystathionine beta-synthase null homocystinuric mice fail to exhibit altered hemostasis or lowering of plasma homocysteine in response to betaine treatment.

Journal: Molecular genetics and metabolism20101001

Title: Aza-1,2,3-triazole-3-alanine synthesis via copper-catalyzed 1,3-dipolar cycloaddition on aza-progargylglycine.

Journal: The Journal of organic chemistry20100806

Title: A crucial role for hydrogen sulfide in oxygen sensing via modulating large conductance calcium-activated potassium channels.

Journal: Antioxidants & redox signaling20100515

Title: Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H(2)S production.

Journal: Antioxidants & redox signaling20100515

Title: Vasoactivity of hydrogen sulfide in normoxic and anoxic turtles (Trachemys scripta).

Journal: American journal of physiology. Regulatory, integrative and comparative physiology20100501

Title: Differing effects of exogenous and endogenous hydrogen sulphide in carrageenan-induced knee joint synovitis in the rat.

Journal: British journal of pharmacology20100401

Title: Inhibition of endogenous hydrogen sulfide synthesis by PAG protects against ethanol-induced gastric damage in the rat.

Journal: European journal of pharmacology20100325

Title: Glutathione depletion causes a JNK and p38MAPK-mediated increase in expression of cystathionine-gamma-lyase and upregulation of the transsulfuration pathway in C6 glioma cells.

Journal: Neurochemistry international20100301

Title: L-cysteine stimulates hydrogen sulfide synthesis in myocardium associated with attenuation of ischemia-reperfusion injury.

Journal: Journal of cardiovascular pharmacology and therapeutics20100301

Title: Hydrogen sulfide promotes transient receptor potential vanilloid 1-mediated neurogenic inflammation in polymicrobial sepsis.

Journal: Critical care medicine20100201

Title: The structure of the proline utilization a proline dehydrogenase domain inactivated by N-propargylglycine provides insight into conformational changes induced by substrate binding and flavin reduction.

Journal: Biochemistry20100126

Title: Role of hydrogen sulfide in severe burn injury-induced inflammation in mice.

Journal: Molecular medicine (Cambridge, Mass.)20100101

Title: Cysteinyl-glycine in the control of glutathione homeostasis in bovine lenses.

Journal: Molecular vision20100101

Title: Hydrogen sulfide induces apoptosis of pulmonary artery smooth muscle cell in rats with pulmonary hypertension induced by high pulmonary blood flow.

Journal: Chinese medical journal20091220

Title: Thermal melting studies of alkyne- and ferrocene-containing PNA bioconjugates.

Journal: Organic & biomolecular chemistry20091207

Title: Regulation of [3H] D-aspartate release from mammalian isolated retinae by hydrogen sulfide.

Journal: Neurochemical research20091101

Title: Application of copper(I) catalyzed azide-alkyne [3+2] cycloaddition to the synthesis of template-assembled multivalent peptide conjugates.

Journal: Organic & biomolecular chemistry20091021

Title: Astrocytes produce the antiinflammatory and neuroprotective agent hydrogen sulfide.

Journal: Neurobiology of aging20091001

Title: Extracellular redox modulation by regulatory T cells.

Journal: Nature chemical biology20091001

Title: Hydrogen sulfide prevents ethanol-induced gastric damage in mice: role of ATP-sensitive potassium channels and capsaicin-sensitive primary afferent neurons.

Journal: The Journal of pharmacology and experimental therapeutics20090901

Title: S-propargyl-cysteine protects both adult rat hearts and neonatal cardiomyocytes from ischemia/hypoxia injury: the contribution of the hydrogen sulfide-mediated pathway.

Journal: Journal of cardiovascular pharmacology20090801

Title: Cardioprotective effect of hydrogen sulfide in ischemic reperfusion experimental rats and its influence on expression of survivin gene.

Journal: Biological & pharmaceutical bulletin20090801

Title: Efficient screening for new amino acid dehydrogenase activity: directed evolution of Bacillus sphaericus phenylalanine dehydrogenase towards activity with an unsaturated non-natural amino acid.

Journal: Journal of biotechnology20090615

Title: Hydrogen sulfide as a novel mediator for pancreatic pain in rodents.

Journal: Gut20090601

Title: Production and actions of hydrogen sulfide, a novel gaseous bioactive substance, in the kidneys.

Journal: The Journal of pharmacology and experimental therapeutics20090601

Title: Endogenous hydrogen sulfide regulates pulmonary artery collagen remodeling in rats with high pulmonary blood flow.

Journal: Experimental biology and medicine (Maywood, N.J.)20090501

Title: Synthesis and characterization of dicobalthexacarbonyl-alkyne derivatives of amino acids, peptides, and peptide nucleic acid (PNA) monomers.

Journal: Inorganic chemistry20090406

Title: [Role of hydrogen sulfide/cystathionine-gamma-lyase system in acute lung injury induced by lipopolysaccharide in rats].

Journal: Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue20090401

Title: Synthesis and aromatisation of cyclic enediyne-containing amino acids.

Journal: Organic & biomolecular chemistry20090221

Title: Role of hydrogen sulfide in the development of atherosclerotic lesions in apolipoprotein E knockout mice.

Journal: Arteriosclerosis, thrombosis, and vascular biology20090201

Title: Pancreatic islet overproduction of H2S and suppressed insulin release in Zucker diabetic rats.

Journal: Laboratory investigation; a journal of technical methods and pathology20090101

Title: Down-regulation of endogenous hydrogen sulphide pathway in nasal mucosa of allergic rhinitis in guinea pigs.

Journal: Allergologia et immunopathologia20090101

Title: DYRK1A, a novel determinant of the methionine-homocysteine cycle in different mouse models overexpressing this Down-syndrome-associated kinase.

Journal: PloS one20090101

Title: Inhibitory action of hydrogen sulfide on muscarinic receptor-induced contraction of isolated porcine irides.

Journal: Experimental eye research20081201

Title: H2S contributes to the hepatic arterial buffer response and mediates vasorelaxation of the hepatic artery via activation of K(ATP) channels.

Journal: American journal of physiology. Gastrointestinal and liver physiology20081201

Title: Novel glycated [99mTc(CO)3]-labeled bombesin analogues for improved targeting of gastrin-releasing peptide receptor-positive tumors.

Journal: Bioconjugate chemistry20081201

Title: Tags for labeling protein N-termini with subtiligase for proteomics.

Journal: Bioorganic & medicinal chemistry letters20081115

Title: Expanding the genetic code of Saccharomyces cerevisiae with methionine analogues.

Journal: Yeast (Chichester, England)20081101

Title: Hydrogen sulphide is pro-inflammatory in haemorrhagic shock.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.]20081101

Title: Convenient syntheses of homopropargylglycine.

Journal: Journal of peptide science : an official publication of the European Peptide Society20081001

Title: Endogenous hydrogen sulphide mediates the cardioprotection induced by ischemic postconditioning.

Journal: American journal of physiology. Heart and circulatory physiology20080901

Title: [Effects of hydrogen sulfide on vascular inflammation in pulmonary hypertension induced by high pulmonary blood flow: experiment with rats].

Journal: Zhonghua yi xue za zhi20080819

Title: Synthesis and conformational analysis of a cyclic peptide obtained via i to i+4 intramolecular side-chain to side-chain azide-alkyne 1,3-dipolar cycloaddition.

Journal: The Journal of organic chemistry20080801

Title: The role of cysteine 116 in the active site of the antitumor enzyme L-methionine gamma-lyase from Pseudomonas putida.

Journal: Bioscience, biotechnology, and biochemistry20080701

Title: [The role of hydrogen sulfide and cystathionine-gamma-lyase in allergic rhinitis guinea pigs].

Journal: Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery20080701

Title: Ribosomal synthesis of bicyclic peptides via two orthogonal inter-side-chain reactions.

Journal: Journal of the American Chemical Society20080611

Title: Hydrogen sulfide protects rat lung from ischemia-reperfusion injury.

Journal: Life sciences20080606

Title: [Hypotensive effects of hydrogen sulfide via attenuating vascular inflammation in spontaneously hypertensive rats].

Journal: Zhonghua xin xue guan bing za zhi20080601

Title: Structural basis for the inactivation of Thermus thermophilus proline dehydrogenase by N-propargylglycine.

Journal: Biochemistry20080520

Title: Inhibition of hydrogen sulfide synthesis attenuates chemokine production and protects mice against acute pancreatitis and associated lung injury.

Journal: Pancreas20080501

Title: Pro-inflammatory effects of hydrogen sulphide on substance P in caerulein-induced acute pancreatitis.

Journal: Journal of cellular and molecular medicine20080401

Title: A nociceptive-intensity-dependent role for hydrogen sulphide in the formalin model of persistent inflammatory pain.

Journal: Neuroscience20080303

Title: Endogenous hydrogen sulfide regulates leukocyte trafficking in cecal ligation and puncture-induced sepsis.

Journal: Journal of leukocyte biology20071001

Title: The regulatory effect of endogenous hydrogen sulfide on pulmonary vascular structure and gasotransmitters in rats with high pulmonary blood flow.

Journal: Life sciences20070816

Title: Hydrogen sulfide facilitates carotid sinus baroreceptor activity in anesthetized male rats.

Journal: Chinese medical journal20070805

Title: Activation of apoptosis signal regulating kinase 1 (ASK1) and translocation of death-associated protein, Daxx, in substantia nigra pars compacta in a mouse model of Parkinson's disease: protection by alpha-lipoic acid.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology20070701

Title: [Relationship between hydrogen sulfide and myocardial damage in endotoxemic rats].

Journal: Sheng li xue bao : [Acta physiologica Sinica]20070625

Title: Hydrogen sulfide acts as an inflammatory mediator in cecal ligation and puncture-induced sepsis in mice by upregulating the production of cytokines and chemokines via NF-kappaB.

Journal: American journal of physiology. Lung cellular and molecular physiology20070401

Title: Hydrogen sulfide and its possible roles in myocardial ischemia in experimental rats.

Journal: Journal of applied physiology (Bethesda, Md. : 1985)20070101

Title: Monocyte differentiation, activation, and mycobacterial killing are linked to transsulfuration-dependent redox metabolism.

Journal: The Journal of biological chemistry20061215

Title: Interaction between hydrogen sulfide/cystathionine gamma-lyase and carbon monoxide/heme oxygenase pathways in aortic smooth muscle cells.

Journal: Acta pharmacologica Sinica20061201

Title: Hydrogen sulfide is a novel prosecretory neuromodulator in the Guinea-pig and human colon.

Journal: Gastroenterology20061101

Title: Cysteine biosynthesis in Trichomonas vaginalis involves cysteine synthase utilizing O-phosphoserine.

Journal: The Journal of biological chemistry20060901

Title: The production of hydrogen sulfide limits myocardial ischemia and reperfusion injury and contributes to the cardioprotective effects of preconditioning with endotoxin, but not ischemia in the rat.

Journal: Shock (Augusta, Ga.)20060801

Title: Role of hydrogen sulfide in cecal ligation and puncture-induced sepsis in the mouse.

Journal: American journal of physiology. Lung cellular and molecular physiology20060601

Title: [Impact of hydrogen sulfide, a novel gaseous signal molecule on nitric oxide/nitric oxide synthase pathway in left-to-right shunt: experiment with rats].

Journal: Zhonghua yi xue za zhi20060523

Title: Possible role for the novel gasotransmitter hydrogen sulphide in erectile dysfunction--a pilot study.

Journal: European journal of pharmacology20060327

Title: Hydrogen sulfide facilitates carotid sinus baroreflex in anesthetized rats.

Journal: Acta pharmacologica Sinica20060301

Title: Cystathionine gamma-lyase contributes to selenomethionine detoxification and cytosolic glutathione peroxidase biosynthesis in mouse liver.

Journal: Biological trace element research20060201

Title: Endogenous hydrogen sulfide contributes to the cardioprotection by metabolic inhibition preconditioning in the rat ventricular myocytes.

Journal: Journal of molecular and cellular cardiology20060101

Title: D-amino-acid oxidase is involved in D-serine-induced nephrotoxicity.

Journal: Chemical research in toxicology20051101

Title: Inhibition of endogenous hydrogen sulfide formation reduces the organ injury caused by endotoxemia.

Journal: British journal of pharmacology20051001

Title: Hydrogen sulfide is a novel mediator of lipopolysaccharide-induced inflammation in the mouse.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology20050701

Title: Hydrogen sulphide is a mediator of carrageenan-induced hindpaw oedema in the rat.

Journal: British journal of pharmacology20050501

Title: Role of hydrogen sulfide in acute pancreatitis and associated lung injury.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology20050401

Title: Functional demonstration of reverse transsulfuration in the Mycobacterium tuberculosis complex reveals that methionine is the preferred sulfur source for pathogenic Mycobacteria.

Journal: The Journal of biological chemistry20050304

Title: Age-associated oxidative damage leads to absence of gamma-cystathionase in over 50% of rat lenses: relevance in cataractogenesis.

Journal: Free radical biology & medicine20050301

Title: Hydrogen sulfide as an endogenous modulator of biliary bicarbonate excretion in the rat liver.

Journal: Antioxidants & redox signaling20050101

Title: Role of hydrogen sulphide in haemorrhagic shock in the rat: protective effect of inhibitors of hydrogen sulphide biosynthesis.

Journal: British journal of pharmacology20041201

Title: The presence of a transsulfuration pathway in the lens: a new oxidative stress defense system.

Journal: Experimental eye research20041201

Title: A chemoenzymatic approach to glycopeptide antibiotics.

Journal: Journal of the American Chemical Society20041103

Title: Aviglycine and propargylglycine inhibit conidial germination and mycelial growth of Fusarium oxysporumf. sp. luffae.

Journal: Mycopathologia20041001

Title: [The regulation of carbon monoxide/heme oxygenase system by hydrogen sulfide in rats with hypoxic pulmonary hypertension].

Journal: Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases20041001

Title: Reversal of acquired cisplatin resistance by modulation of metallothionein in transplanted murine tumors.

Journal: International journal of urology : official journal of the Japanese Urological Association20040601

Title: Impact of hydrogen sulfide on carbon monoxide/heme oxygenase pathway in the pathogenesis of hypoxic pulmonary hypertension.

Journal: Biochemical and biophysical research communications20040423

Title: The possible role of hydrogen sulfide on the pathogenesis of spontaneous hypertension in rats.

Journal: Biochemical and biophysical research communications20040102

Title: Modulation of endogenous production of H2S in rat tissues.

Journal: Canadian journal of physiology and pharmacology20030901

Title: Inhibition of liver trans-sulphuration pathway by propargylglycine mimics gene expression changes found in the mammary gland of weaned lactating rats: role of glutathione.

Journal: The Biochemical journal20030801

Title: Effect of acute betaine administration on hepatic metabolism of S-amino acids in rats and mice.

Journal: Biochemical pharmacology20030501

Title: The smooth muscle relaxant effect of hydrogen sulphide in vitro: evidence for a physiological role to control intestinal contractility.

Journal: British journal of pharmacology20020901

Title: Structure of external aldimine of Escherichia coli CsdB, an IscS/NifS homolog: implications for its specificity toward selenocysteine.

Journal: Journal of biochemistry20020501

Title: Cystathionine pathway-dependent cytotoxicities of diethyl maleate and diamide in rat and human hepatoma-derived cell cultures.

Journal: Alternatives to laboratory animals : ATLA20020101

Title: Cysteine regulates expression of cysteine dioxygenase and gamma-glutamylcysteine synthetase in cultured rat hepatocytes.

Journal: American journal of physiology. Endocrinology and metabolism20010501

Title: Development of new carboxylic acid-based MMP inhibitors derived from functionalized propargylglycines.

Journal: Journal of medicinal chemistry20010329

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