64211-46-7,MFCD01727545
Catalog No.:AA00IB9A

64211-46-7 | Ethanone, 1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)-,O-[(2,4-dichlorophenyl)methyl]oxime, (1Z)-, mononitrate

Pack Size
Purity
Availability
Price(USD)
Quantity
  
10mg
in stock  
$165.00   $115.00
- +
1g
≥98%
in stock  
$168.00   $117.00
- +
5g
≥98%
in stock  
$496.00   $347.00
- +
25g
≥98%
in stock  
$1,648.00   $1,153.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00IB9A
Chemical Name:
Ethanone, 1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)-,O-[(2,4-dichlorophenyl)methyl]oxime, (1Z)-, mononitrate
CAS Number:
64211-46-7
Molecular Formula:
C18H14Cl4N4O4
Molecular Weight:
492.1402
MDL Number:
MFCD01727545
SMILES:
Clc1ccc(c(c1)Cl)CON=C(c1ccc(cc1Cl)Cl)Cn1cncc1.[O-][N+](=O)O
NSC Number:
758958
Properties
Properties
 
Form:
Solid  
MP:
136-138℃  
Storage:
2-8℃;  

Computed Properties
 
Complexity:
506  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
1  
Formal Charge:
0  
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0  
Rotatable Bond Count:
6  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  

Downstream Synthesis Route
Literature

Title: Why are most phospholipidosis inducers also hERG blockers?

Journal: Archives of toxicology 20171201

Title: AroER tri-screen is a biologically relevant assay for endocrine disrupting chemicals modulating the activity of aromatase and/or the estrogen receptor.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20140501

Title: FDA-approved drugs and other compounds tested as inhibitors of human glutathione transferase P1-1.

Journal: Chemico-biological interactions 20130905

Title: Ototoxic effect of topical oxiconazole and terbinafine in rats.

Journal: Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale 20120401

Title: Clear-cell papulosis: a rare entity that may be misconstrued pathologically as normal skin.

Journal: Pediatric dermatology 20120101

Title: Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2.

Journal: Journal of medicinal chemistry 20110714

Title: Antileishmanial activity of benzocycloalkyl azole oximino ethers: the conformationally constraint analogues of oxiconazole.

Journal: Acta tropica 20110201

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Cladophialophora saturnica sp. nov., a new opportunistic species of Chaetothyriales revealed using molecular data.

Journal: Medical mycology 20090201

Title: Tetrahydronaphthyl azole oxime ethers: the conformationally rigid analogues of oxiconazole as antibacterials.

Journal: European journal of medicinal chemistry 20090101

Title: Imidazole antifungals, but not triazole antifungals, increase membrane Zn2+ permeability in rat thymocytes Possible contribution to their cytotoxicity.

Journal: Toxicology 20080627

Title: Azole antimycotics differentially affect rifampicin-induced pregnane X receptor-mediated CYP3A4 gene expression.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20080201

Title: Molecular properties of oxyconazole and tioconazole as the criteria for their bioavailability estimation.

Journal: Acta poloniae pharmaceutica 20080101

Title: Oxime and oxime ether derivatives of 1,4-benzothiazine related to oxiconazole.

Journal: ChemMedChem 20070801

Title: Combination of surgical avulsion and topical therapy for single nail onychomycosis: a randomized controlled trial.

Journal: The British journal of dermatology 20070801

Title: Activated pregnenolone X-receptor is a target for ketoconazole and its analogs.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20070415

Title: An experience from an outbreak of tinea capitis gladiatorum due to Trichophyton tonsurans.

Journal: Clinical and experimental dermatology 20060301

Title: Spectrophotometric determination of oxiconazole in topical lotion using methyl orange.

Journal: Journal of pharmaceutical and biomedical analysis 20050401

Title: Susceptibility to some antifungal drugs of vaginal lactobacilli isolated from healthy women.

Journal: Drug metabolism and drug interactions 20050101

Title: Synthesis, antifungal activity, and molecular modeling studies of new inverted oxime ethers of oxiconazole.

Journal: Journal of medicinal chemistry 20021024

Title: LC method for the analysis of Oxiconazole in pharmaceutical formulations.

Journal: Journal of pharmaceutical and biomedical analysis 20020905

Title: [The in vitro properties of a new hydroxypyridone antimycotic rilopirox, with special reference to its anti-Candida activity].

Journal: The Japanese journal of antibiotics 19990201

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SDS
Related Products of 64211-46-7
Tags:64211-46-7 Molecular Formula|64211-46-7 MDL|64211-46-7 SMILES|64211-46-7 Ethanone, 1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)-,O-[(2,4-dichlorophenyl)methyl]oxime, (1Z)-, mononitrate
Catalog No.: AA00IB9A
64211-46-7,MFCD01727545
64211-46-7 | Ethanone, 1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)-,O-[(2,4-dichlorophenyl)methyl]oxime, (1Z)-, mononitrate
Pack Size: 10mg
Purity:
in stock
$165.00 $115.00
Pack Size: 1g
Purity: ≥98%
in stock
$168.00 $117.00
Pack Size: 5g
Purity: ≥98%
in stock
$496.00 $347.00
Pack Size: 25g
Purity: ≥98%
in stock
$1,648.00 $1,153.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA00IB9A
Chemical Name: Ethanone, 1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)-,O-[(2,4-dichlorophenyl)methyl]oxime, (1Z)-, mononitrate
CAS Number: 64211-46-7
Molecular Formula: C18H14Cl4N4O4
Molecular Weight: 492.1402
MDL Number: MFCD01727545
SMILES: Clc1ccc(c(c1)Cl)CON=C(c1ccc(cc1Cl)Cl)Cn1cncc1.[O-][N+](=O)O
NSC Number: 758958
Properties
Form: Solid  
MP: 136-138℃  
Storage: 2-8℃;  
Complexity: 506  
Covalently-Bonded Unit Count: 2  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 1  
Formal Charge: 0  
Heavy Atom Count: 30  
Hydrogen Bond Acceptor Count: 6  
Hydrogen Bond Donor Count: 1  
Isotope Atom Count: 0  
Rotatable Bond Count: 6  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
Downstream Synthesis Route
Literature fold

Title: Why are most phospholipidosis inducers also hERG blockers?

Journal: Archives of toxicology20171201

Title: AroER tri-screen is a biologically relevant assay for endocrine disrupting chemicals modulating the activity of aromatase and/or the estrogen receptor.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20140501

Title: FDA-approved drugs and other compounds tested as inhibitors of human glutathione transferase P1-1.

Journal: Chemico-biological interactions20130905

Title: Ototoxic effect of topical oxiconazole and terbinafine in rats.

Journal: Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale20120401

Title: Clear-cell papulosis: a rare entity that may be misconstrued pathologically as normal skin.

Journal: Pediatric dermatology20120101

Title: Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2.

Journal: Journal of medicinal chemistry20110714

Title: Antileishmanial activity of benzocycloalkyl azole oximino ethers: the conformationally constraint analogues of oxiconazole.

Journal: Acta tropica20110201

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters20101101

Title: Cladophialophora saturnica sp. nov., a new opportunistic species of Chaetothyriales revealed using molecular data.

Journal: Medical mycology20090201

Title: Tetrahydronaphthyl azole oxime ethers: the conformationally rigid analogues of oxiconazole as antibacterials.

Journal: European journal of medicinal chemistry20090101

Title: Imidazole antifungals, but not triazole antifungals, increase membrane Zn2+ permeability in rat thymocytes Possible contribution to their cytotoxicity.

Journal: Toxicology20080627

Title: Azole antimycotics differentially affect rifampicin-induced pregnane X receptor-mediated CYP3A4 gene expression.

Journal: Drug metabolism and disposition: the biological fate of chemicals20080201

Title: Molecular properties of oxyconazole and tioconazole as the criteria for their bioavailability estimation.

Journal: Acta poloniae pharmaceutica20080101

Title: Oxime and oxime ether derivatives of 1,4-benzothiazine related to oxiconazole.

Journal: ChemMedChem20070801

Title: Combination of surgical avulsion and topical therapy for single nail onychomycosis: a randomized controlled trial.

Journal: The British journal of dermatology20070801

Title: Activated pregnenolone X-receptor is a target for ketoconazole and its analogs.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research20070415

Title: An experience from an outbreak of tinea capitis gladiatorum due to Trichophyton tonsurans.

Journal: Clinical and experimental dermatology20060301

Title: Spectrophotometric determination of oxiconazole in topical lotion using methyl orange.

Journal: Journal of pharmaceutical and biomedical analysis20050401

Title: Susceptibility to some antifungal drugs of vaginal lactobacilli isolated from healthy women.

Journal: Drug metabolism and drug interactions20050101

Title: Synthesis, antifungal activity, and molecular modeling studies of new inverted oxime ethers of oxiconazole.

Journal: Journal of medicinal chemistry20021024

Title: LC method for the analysis of Oxiconazole in pharmaceutical formulations.

Journal: Journal of pharmaceutical and biomedical analysis20020905

Title: [The in vitro properties of a new hydroxypyridone antimycotic rilopirox, with special reference to its anti-Candida activity].

Journal: The Japanese journal of antibiotics19990201

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