+1 858-523-8231
Login | Register
menu
AA Blocks, Building Blocks, Catalysts, Inhibitors
Login | Register
668467-91-2,MFCD09037562
Catalog No.:AA00FBGD

668467-91-2 | LDN-57444

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$21.00   $15.00
- +
5mg
98%
in stock  
$58.00   $41.00
- +
10mg
98%
in stock  
$98.00   $68.00
- +
50mg
98%
in stock  
$291.00   $204.00
- +
100mg
98%
in stock  
$438.00   $307.00
- +
250mg
98%
in stock  
$591.00   $414.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00FBGD
Chemical Name:
LDN-57444
CAS Number:
668467-91-2
Molecular Formula:
C17H11Cl3N2O3
Molecular Weight:
397.6398
MDL Number:
MFCD09037562
SMILES:
CC(=O)ON=C1c2cc(Cl)ccc2N(C1=O)Cc1cc(Cl)ccc1Cl
Properties
Properties
 
Form:
Solid  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
571  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
1  
Formal Charge:
0  
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
0  
Isotope Atom Count:
0  
Rotatable Bond Count:
4  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
4.6  

Literature

Title: Control of BACE1 degradation and APP processing by ubiquitin carboxyl-terminal hydrolase L1.

Journal: Journal of neurochemistry 20120301

Title: Regulation of synaptic structure by ubiquitin C-terminal hydrolase L1.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090617

Title: Liu Y, et al. Discovery of inhibitors that elucidate the role of UCH-L1 activity in the H1299 lung cancer cell line. Chem Biol. 2003 Sep;10(9):837-46.

Title: Gong B, et al. Ubiquitin hydrolase Uch-L1 rescues beta-amyloid-induced decreases in synaptic function and contextual memory. Cell. 2006 Aug 25;126(4):775-88.

Title: Tan YY, et al. Endoplasmic reticulum stress contributes to the cell death induced by UCH-L1 inhibitor. Mol Cell Biochem. 2008 Nov;318(1-2):109-15.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
Submit
SDS
Related Products of 668467-91-2
Building Blocks
More >
Tags:668467-91-2 Molecular Formula|668467-91-2 MDL|668467-91-2 SMILES|668467-91-2 LDN-57444
Catalog No.: AA00FBGD
668467-91-2,MFCD09037562
668467-91-2 | LDN-57444
Pack Size： 1mg
Purity： 98%
in stock
$21.00 $15.00
Pack Size： 5mg
Purity： 98%
in stock
$58.00 $41.00
Pack Size： 10mg
Purity： 98%
in stock
$98.00 $68.00
Pack Size： 50mg
Purity： 98%
in stock
$291.00 $204.00
Pack Size： 100mg
Purity： 98%
in stock
$438.00 $307.00
Pack Size： 250mg
Purity： 98%
in stock
$591.00 $414.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA00FBGD
Chemical Name: LDN-57444
CAS Number: 668467-91-2
Molecular Formula: C17H11Cl3N2O3
Molecular Weight: 397.6398
MDL Number: MFCD09037562
SMILES: CC(=O)ON=C1c2cc(Cl)ccc2N(C1=O)Cc1cc(Cl)ccc1Cl
Properties
Form: Solid  
Storage: Keep in dry area;2-8℃;  
Complexity: 571  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 1  
Formal Charge: 0  
Heavy Atom Count: 25  
Hydrogen Bond Acceptor Count: 4  
Hydrogen Bond Donor Count: 0  
Isotope Atom Count: 0  
Rotatable Bond Count: 4  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 4.6  
Literature fold

Title: Control of BACE1 degradation and APP processing by ubiquitin carboxyl-terminal hydrolase L1.

Journal: Journal of neurochemistry20120301

Title: Regulation of synaptic structure by ubiquitin C-terminal hydrolase L1.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20090617

Title: Liu Y, et al. Discovery of inhibitors that elucidate the role of UCH-L1 activity in the H1299 lung cancer cell line. Chem Biol. 2003 Sep;10(9):837-46.

Title: Gong B, et al. Ubiquitin hydrolase Uch-L1 rescues beta-amyloid-induced decreases in synaptic function and contextual memory. Cell. 2006 Aug 25;126(4):775-88.

Title: Tan YY, et al. Endoplasmic reticulum stress contributes to the cell death induced by UCH-L1 inhibitor. Mol Cell Biochem. 2008 Nov;318(1-2):109-15.

Related Products of of 668467-91-2
Building Blocks More >
71083-00-6
71083-00-6
Ethyl 6-fluoro-4-oxo-1H-quinoline-3-carboxylate
AA00FBOB | MFCD03990483
71569-15-8
71569-15-8
5-Amino-5,6,7,8-tetrahydroquinoline
AA00FBSE | MFCD04038438
697299-86-8
697299-86-8
(4-Bromothiazol-2-yl)methanamine
AA00FBZE | MFCD12913879
66557-64-0
66557-64-0
2-(1H-BENZOIMIDAZOL-2-YLMETHYL)-BENZOTHIAZOLE
AA00FC43 | MFCD00856881
747-45-5
747-45-5
QUINIDINE BISULFATE
AA00FCBS | MFCD00190161
68554-69-8
68554-69-8
METHYLHYDROSILOXANE - OCTYLMETHYLSILOXANE COPOLYMER
AA00FCLV
66631-29-6
66631-29-6
4-(1H-Benzo[d]imidazol-2-yl)benzoic acid
AA00FCW9 | MFCD00443919
67686-05-9
67686-05-9
Ethyl 2-(1-methylpiperidin-4-yl)acetate
AA00FD15 | MFCD11100758
691394-24-8
691394-24-8
PIPERAZIN-1-YL-O-TOLYL-METHANONE HYDROCHLORIDE
AA00FD5U | MFCD08444058
65947-37-7
65947-37-7
.beta.-D-Glucopyranoside, 2-propenyl 2-(acetylamino)-2-deoxy-4,6-O-(phenylmethylene)-
AA00FDB3 | MFCD15144923
Submit
© 2017 AA BLOCKS, INC. All rights reserved.