Name: Name:7-Chloro-l-tryptophan
Brand: AABLOCKS
SKU: AA00FB02
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA00FB02

Chemical Name: 7-Chloro-l-tryptophan

CAS Number: 73945-46-7

Molecular Formula: C11H11ClN2O2

Molecular Weight: 238.6702

MDL Number: MFCD09264322

SMILES: N[C@H](C(=O)O)Cc1c[nH]c2c1cccc2Cl

Properties

Complexity: 275

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 1

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 16

Hydrogen Bond Acceptor Count: 3

Hydrogen Bond Donor Count: 3

Isotope Atom Count: 0

Rotatable Bond Count: 3

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: -0.4

Literature fold

Title: Reengineering a tryptophan halogenase to preferentially chlorinate a direct alkaloid precursor.

Journal: Journal of the American Chemical Society20111207

Title: Changing the regioselectivity of the tryptophan 7-halogenase PrnA by site-directed mutagenesis.

Journal: Angewandte Chemie (International ed. in English)20110321

Title: Biosynthetic gene cluster for the cladoniamides, bis-indoles with a rearranged scaffold.

Journal: PloS one20110101

Title: Effects of nutrients on quorum signals and secondary metabolite productions of Burkholderia sp. O33.

Journal: Journal of microbiology and biotechnology20091001

Title: Tandem action of the O2- and FADH2-dependent halogenases KtzQ and KtzR produce 6,7-dichlorotryptophan for kutzneride assembly.

Journal: Journal of the American Chemical Society20081029

Title: Halogenase genes in nonribosomal peptide synthetase gene clusters of Microcystis (cyanobacteria): sporadic distribution and evolution.

Journal: Molecular biology and evolution20080901

Title: The second enzyme in pyrrolnitrin biosynthetic pathway is related to the heme-dependent dioxygenase superfamily.

Journal: Biochemistry20071030

Title: Chlorination by a long-lived intermediate in the mechanism of flavin-dependent halogenases.

Journal: Biochemistry20070206

Title: Preliminary crystallographic characterization of PrnB, the second enzyme in the pyrrolnitrin biosynthetic pathway.

Journal: Acta crystallographica. Section F, Structural biology and crystallization communications20061101

Title: Flavin redox chemistry precedes substrate chlorination during the reaction of the flavin-dependent halogenase RebH.

Journal: Biochemistry20060627

Title: Tryptophan 7-halogenase (PrnA) structure suggests a mechanism for regioselective chlorination.

Journal: Science (New York, N.Y.)20050930

73945-46-7 | 7-Chloro-l-tryptophan