Title: Chemical composition of hexane extract of Citrus aurantifolia and anti-Mycobacterium tuberculosis activity of some of its constituents.
Journal: Molecules (Basel, Switzerland)20120919
Title: Bergamottin is a competitive inhibitor of CYP1A1 and is antimutagenic in the Ames test.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association20120901
Title: Grapefruit (Citrus paradisi Macfad) phytochemicals composition is modulated by household processing techniques.
Journal: Journal of food science20120901
Title: Identification of the residue in human CYP3A4 that is covalently modified by bergamottin and the reactive intermediate that contributes to the grapefruit juice effect.
Journal: Drug metabolism and disposition: the biological fate of chemicals20120501
Title: Structure-activity relationships for naturally occurring coumarins as β-secretase inhibitor.
Journal: Bioorganic & medicinal chemistry20120115
Title: Major furocoumarins in grapefruit juice I: levels and urinary metabolite(s).
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association20111201
Title: Construction of a model to estimate the CYP3A inhibitory effect of grapefruit juice.
Journal: Die Pharmazie20110701
Title: Effect of maturity, processing, and storage on the furanocoumarin composition of grapefruit and grapefruit juice.
Journal: Journal of food science20110501
Title: Food-drug interactions: grapefruit juice.
Journal: Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi20110101
Title: A quantitative high-throughput 96-well plate fluorescence assay for mechanism-based inactivators of cytochromes P450 exemplified using CYP2B6.
Journal: Nature protocols20100901
Title: Suppression of phorbol-12-myristate-13-acetate-induced tumor cell invasion by bergamottin via the inhibition of protein kinase Cdelta/p38 mitogen-activated protein kinase and JNK/nuclear factor-kappaB-dependent matrix metalloproteinase-9 expression.
Journal: Molecular nutrition & food research20100701
Title: White and colored grapefruit juice produce similar pharmacokinetic interactions.
Journal: Die Pharmazie20080801
Title: [Contents of furanocoumarins in grapefruit juice and health foods].
Journal: Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan20080801
Title: Effect of grapefruit juice, naringin, naringenin, and bergamottin on the intestinal carrier-mediated transport of talinolol in rats.
Journal: Journal of agricultural and food chemistry20080625
Title: Aspergillus niger metabolism of citrus furanocoumarin inhibitors of human cytochrome P450 3A4.
Journal: Applied microbiology and biotechnology20080201
Title: Determination of bergamottin in human plasma after grapefruit juice ingestion by an UPLC/MS/MS method.
Journal: Die Pharmazie20080201
Title: Grapefruit juice-drug interactions: Grapefruit juice and its components inhibit P-glycoprotein (ABCB1) mediated transport of talinolol in Caco-2 cells.
Journal: Journal of pharmaceutical sciences20071001
Title: The use of heat treatment to eliminate drug interactions due to grapefruit juice.
Journal: Biological & pharmaceutical bulletin20061101
Title: Metabolism of bergamottin by cytochromes P450 2B6 and 3A5.
Journal: The Journal of pharmacology and experimental therapeutics20060901
Title: Synthesis of 8-geranyloxypsoralen analogues and their evaluation as inhibitors of CYP3A4.
Journal: Bioorganic & medicinal chemistry20060601
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology20060501
Title: Design, synthesis and evaluation of furanocoumarin monomers as inhibitors of CYP3A4.
Journal: Organic & biomolecular chemistry20060421
Title: Variation of flavonoids and furanocoumarins in grapefruit juices: a potential source of variability in grapefruit juice-drug interaction studies.
Journal: Journal of agricultural and food chemistry20060111
Title: The grapefruit juice effect is not limited to cytochrome P450 (P450) 3A4: evidence for bergamottin-dependent inactivation, heme destruction, and covalent binding to protein in P450s 2B6 and 3A5.
Journal: The Journal of pharmacology and experimental therapeutics20050401
Title: Probable interaction of bergamottin and cyclosporine in a lung transplant recipient.
Journal: Transplantation20050327
Title: Two major grapefruit juice components differ in time to onset of intestinal CYP3A4 inhibition.
Journal: The Journal of pharmacology and experimental therapeutics20050301
Title: Coumarins are competitive inhibitors of cytochrome P450 1B1, with equal potency for allelic variants.
Journal: Pharmacogenetics and genomics20050301
Title: Photodynamic and photo-cross-linking potential of bergamottin.
Journal: Die Pharmazie20050101
Title: Bergamottin contribution to the grapefruit juice-felodipine interaction and disposition in humans.
Journal: Clinical pharmacology and therapeutics20041201
Title: Inhibition of in-vitro simvastatin metabolism in rat liver microsomes by bergamottin, a component of grapefruit juice.
Journal: The Journal of pharmacy and pharmacology20040801
Title: CYP450 dietary inhibitors attenuate TNF-alpha-stimulated endothelial molecule expression and leukocyte adhesion.
Journal: American journal of physiology. Cell physiology20040401
Title: Utility of microtiter plate assays for human cytochrome P450 inhibition studies in drug discovery: application of simple method for detecting quasi-irreversible and irreversible inhibitors.
Journal: Drug metabolism and pharmacokinetics20040201
Title: Time course of recovery of cytochrome p450 3A function after single doses of grapefruit juice.
Journal: Clinical pharmacology and therapeutics20030801
Title: Bergamottin, lime juice, and red wine as inhibitors of cytochrome P450 3A4 activity: comparison with grapefruit juice.
Journal: Clinical pharmacology and therapeutics20030601
Title: In vitro inhibition of simvastatin metabolism, a HMG-CoA reductase inhibitor in human and rat liver by bergamottin, a component of grapefruit juice.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences20030101
Title: Effects of bergamottin on human and monkey drug-metabolizing enzymes in primary cultured hepatocytes.
Journal: Drug metabolism and disposition: the biological fate of chemicals20020901
Title: Earl Grey tea intoxication.
Journal: Lancet (London, England)20020427
Title: The effect of bergamottin on diazepam plasma levels and P450 enzymes in beagle dogs.
Journal: Drug metabolism and disposition: the biological fate of chemicals20020201
Title: Role of cytochrome P450 1a1 and 1b1 in the metabolic activation of 7,12-dimethylbenz[a]anthracene and the effects of naturally occurring furanocoumarins on skin tumor initiation.
Journal: Chemical research in toxicology20020201
Title: Inhibition of P-glycoprotein transport function by grapefruit juice psoralen.
Journal: Pharmaceutical research20010401
Title: Effects of furanocoumarin derivatives in grapefruit juice on nifedipine pharmacokinetics in rats.
Journal: Pharmaceutical research20010201
Title: Seville orange juice-felodipine interaction: comparison with dilute grapefruit juice and involvement of furocoumarins.
Journal: Clinical pharmacology and therapeutics20010101
Title: Row EC, et al. Synthesis of 8-geranyloxypsoralen analogues and their evaluation as inhibitors of CYP3A4. Bioorg Med Chem. 2006 Jun 1;14(11):3865-71.
