Title: Role of human sulfotransferase 1A1 and N-acetyltransferase 2 in the metabolic activation of 16 heterocyclic amines and related heterocyclics to genotoxicants in recombinant V79 cells.
Journal: Archives of toxicology20170901
Title: Response surface optimization of effects of some processing variables on carcinogenic/mutagenic heterocyclic aromatic amine (HAA) content in cooked patties.
Journal: Meat science20120701
Title: Antigenotoxic activity of naturally occurring furanocoumarins.
Journal: Environmental and molecular mutagenesis20111001
Title: Naturally occurring food toxins.
Journal: Toxins20100901
Title: Determination of heterocyclic amines in urine samples by capillary liquid chromatography with evaporated light-scattering detection.
Journal: Analytical and bioanalytical chemistry20100501
Title: Validation of an in vitro screening test for predicting the tumor promoting potential of chemicals based on gene expression.
Journal: Toxicology in vitro : an international journal published in association with BIBRA20100401
Title: Implication of replicative stress-related stem cell ageing in radiation-induced murine leukaemia.
Journal: British journal of cancer20090721
Title: Effect of beer/red wine marinades on the formation of heterocyclic aromatic amines in pan-fried beef.
Journal: Journal of agricultural and food chemistry20081126
Title: Mass spectrometric investigation of the sequence selectivity for adduction of heterocyclic aromatic amines on single-strand oligonucleotides.
Journal: Rapid communications in mass spectrometry : RCM20081001
Title: In vitro inhibitory activity of probiotic spore-forming bacilli against genotoxins.
Journal: Letters in applied microbiology20080301
Title: Biochemical basis of genotoxicity of heterocyclic arylamine food mutagens: Human DNA polymerase eta selectively produces a two-base deletion in copying the N2-guanyl adduct of 2-amino-3-methylimidazo[4,5-f]quinoline but not the C8 adduct at the NarI G3 site.
Journal: The Journal of biological chemistry20060901
Title: Lack of formation of heterocyclic amines in fumes from frying French fries.
Journal: Journal of food protection20060901
Title: Differential effects of heterocyclic amines on poly(ADP-ribose) polymerase-1 and mono-ADP-ribosyltransferase A.
Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society20060901
Title: Effect of pH on binding of mutagenic heterocyclic amines by the natural biopolymer poly(gamma-glutamic acid).
Journal: Journal of agricultural and food chemistry20060823
Title: Suppression of MeIQ-induced SOS response by allylbenzenes from Asiasarum heterotropoides in the Salmonella typhimurium OY1001/1A2 umu test.
Journal: Natural product research20060601
Title: Investigation of the separation of heterocyclic aromatic amines by reversed phase ion-pair liquid chromatography coupled with tandem mass spectrometry: the role of ion pair reagents on LC-MS/MS sensitivity.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20051025
Title: Induction of colon tumors in C57BL/6J mice fed MeIQx, IQ, or PhIP followed by dextran sulfate sodium treatment.
Journal: Toxicological sciences : an official journal of the Society of Toxicology20050401
Title: Suppression of chemical mutagen-induced SOS response by allylbenzen from Asiasarum heterotropoides in the Salmonella typhimurium TA1535/PSK1002 umu test.
Journal: Natural product research20050101
Title: Determination of heterocyclic aromatic amines (HAs) content in samples of household-prepared meat dishes.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20040325
Title: Uptake of heterocyclic aromatic amine by insoluble dietary fiber in artificial gastric and intestinal juice.
Journal: Environmental health and preventive medicine20040301
Title: Selection of human cytochrome P450 1A2 mutants with enhanced catalytic activity for heterocyclic amine N-hydroxylation.
Journal: Biochemistry20040203
Title: Functional characterization of four allelic variants of human cytochrome P450 1A2.
Journal: Archives of biochemistry and biophysics20040201
Title: Biphasic effects of the flavonoids quercetin and naringenin on the metabolic activation of 2-amino-3,5-dimethylimidazo[4,5-f]quinoline by Salmonella typhimurium TA1538 co-expressing human cytochrome P450 1A2, NADPH-cytochrome P450 reductase, and cytochrome b5.
Journal: Mutation research20040112
Title: Selected heterocyclic amines.
Journal: Report on carcinogens : carcinogen profiles20040101
Title: Inhibitory effects of (-)-epigallocatechin gallate on the mutation, DNA strand cleavage, and DNA adduct formation by heterocyclic amines.
Journal: Journal of agricultural and food chemistry20030813
Title: Regional mutagenicity of heterocyclic amines in the intestine: mutation analysis of the cII gene in lambda/lacZ transgenic mice.
Journal: Mutation research20030805
Title: Beta-catenin mutations in liver tumors induced by 2-amino-3,4-dimethylimidazo[4,5-f]quinoline in CDF1 mice.
Journal: Cancer letters20030730
Title: Enhancing risk of ethanol on MeIQx-induced rat hepatocarcinogenesis is accompanied with increased levels of cellular proliferation and oxidative stress.
Journal: Cancer letters20030320
Title: Inhibition of mutagenicity of food-derived heterocyclic amines by sulforaphane--a constituent of broccoli.
Journal: Indian journal of experimental biology20030301
Title: Inhibitory effect of dibenzoylmethane on mutagenicity of food-derived heterocyclic amine mutagens.
Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology20030101
Title: Inhibitory effect of curcumin and its natural analogues on genotoxicity of heterocyclic amines from cooked food.
Journal: Indian journal of experimental biology20021201
Title: Mammary gland carcinogenesis by food-derived heterocyclic amines and studies on the mechanisms of carcinogenesis of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
Journal: Mutation research20020930
Title: Estimation of dietary HCA intakes in a large-scale population-based prospective study in Japan.
Journal: Mutation research20020930
Title: Effects of soy sauce and sugar on the formation of heterocyclic amines in marinated foods.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association20020701
Title: Down-regulation of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx)-induced CYP1A2 expression is associated with bovine lactoferrin inhibition of MeIQx-induced liver and colon carcinogenesis in rats.
Journal: Japanese journal of cancer research : Gann20020601
Title: Antimutagenic activities of various lactic acid bacteria against food mutagens: heterocyclic amines.
Journal: The Journal of dairy research20020501
Title: Mutagenic and carcinogenic heterocyclic amines as affected by muscle types/skin and cooking in pan-roasted mackerel.
Journal: Mutation research20020325
Title: Genetic polymorphisms in heterocyclic amine metabolism and risk of colorectal adenomas.
Journal: Pharmacogenetics20020301
Title: Effects of dairy products on heterocyclic aromatic amine-induced rat colon carcinogenesis.
Journal: Carcinogenesis20020301
Title: Antimutagenicity of Murdannia loriformis in the Salmonella mutation assay and its inhibitory effects on azoxymethane-induced DNA methylation and aberrant crypt focus formation in male F344 rats.
Journal: The journal of medical investigation : JMI20020201
Title: Human prostate epithelial cells metabolize chemicals of dietary origin to mutagens.
Journal: Cancer letters20020125
Title: Flavonoids inhibit genetic toxicity produced by carcinogens in cells expressing CYP1A2 and CYP1A1.
Journal: Mutagenesis20020101
Title: Studies on mammary carcinogenesis induced by a heterocyclic amine, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, in mice and rats.
Journal: Environmental and molecular mutagenesis20020101
Title: Mutagenicity of food-derived carcinogens and the effect of antioxidant vitamins.
Journal: Nutrition and cancer20020101
Title: Clean-up procedures for the analysis of heterocyclic aromatic amines (aminoazaarenes) from heat-treated meat samples.
Journal: Journal of chromatography. A20011214
Title: CYP1A2 is expressed along with CYP1A1 in the human lung.
Journal: Cancer letters20010928
Title: Pulmonary Cyp1A1 and CYP1A2 levels and activities in adult male and female offspring of rats exposed during gestation and lactation to 2,3,7, 8-tetrachlorodibenzo-p-dioxin.
Journal: Biochemical pharmacology20010901
Title: A comparison of whole wheat, refined wheat and wheat bran as inhibitors of heterocyclic amines in the Salmonella mutagenicity assay and in the rat colonic aberrant crypt focus assay.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association20010701
Title: LacI transgenic animal study: relationships among DNA-adduct levels, mutant frequencies and cancer incidences.
Journal: Mutation research20010602
Title: CYP1A2 is expressed along with CYP1A1 in the human lung.
Journal: Cancer letters20010310
Title: Inhibitory effects of bitter melon (Momordica charantia Linn.) on bacterial mutagenesis and aberrant crypt focus formation in the rat colon.
Journal: The journal of medical investigation : JMI20010201
Title: Recombinant human P450 forms 1A1, 1A2, and 1B1 catalyze the bioactivation of heterocyclic amine mutagens in Escherichia coli lacZ strains.
Journal: Environmental and molecular mutagenesis20010101
Title: Consistent and fast inhibition of colon carcinogenesis by polyethylene glycol in mice and rats given various carcinogens.
Journal: Cancer research20000615
Title: Inhibition of human cytochrome P450 enzymes by 1,2-dithiole-3-thione, oltipraz and its derivatives, and sulforaphane.
Journal: Chemical research in toxicology20000401
Title: Activation of MeIQ (2-amino-3,4-dimethylimidazo- [4,5-f]quinoline) by sequence variants of recombinant human cytochrome P450 1A2.
Journal: Environmental and molecular mutagenesis20000101
Title: Difference in target organs in carcinogenesis with a heterocyclic amine, 2-amino-3,4-dimethylimidazo[4,5-f]quinoline, in different strains of mice.
Journal: Japanese journal of cancer research : Gann19991101
Title: Interspecies differences in metabolism of heterocyclic aromatic amines by rat and human P450 1A2.
Journal: Cancer letters19990901
Title: Establishment of a Salmonella tester strain highly sensitive to mutagenic heterocylic amines.
Journal: Cancer letters19990901
Title: Chemoprevention of heterocyclic amine-induced carcinogenesis by phenolic compounds in rats.
Journal: Cancer letters19990901
Title: Heterozygous p53-deficient mice are not susceptible to 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) carcinogenicity.
Journal: Cancer letters19990524
Title: Chromosome aberrations induced in mice by chronic feeding of 2-amino-3,4-dimethylimidazo[4,5-f]quinoline (MeIQ).
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association19980601
Title: No direct correlation between mutant frequencies and cancer incidence induced by MeIQ in various organs of Big Blue mice.
Journal: Mutation research19980525
Title: Establishment of a Salmonella tester strain highly sensitive to mutagenic heterocyclic amines.
Journal: Cancer research19980501
Title: Three-dimensional modelling of human cytochrome P450 1A2 and its interaction with caffeine and MeIQ.
Journal: Journal of computer-aided molecular design19970701
Title: Assessing human risk to heterocyclic amines.
Journal: Mutation research19970512
Title: p53 mutations in MeIQ-induced mouse forestomach tumors.
Journal: Nihon Ika Daigaku zasshi19970201
Title: Inhibitory effects of 1-O-hexyl-2,3,5-trimethylhydroquinone (HTHQ), green tea catechins and other antioxidants on 2-amino-6-methyldipyrido[1,2-a:3',2'-d]imidazole (Glu-P-1)-induced rat hepatocarcinogenesis and dose-dependent inhibition by HTHQ of lesion induction by Glu-P-1 or 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx).
Journal: Carcinogenesis19951201
Title: Simultaneous expression of human CYP3A7 and N-acetyltransferase in Chinese hamster CHL cells results in high cytotoxicity for carcinogenic heterocyclic amines.
Journal: Archives of biochemistry and biophysics19950710
Title: Mutation, loss of heterozygosity, and recombination of the p53 gene in mouse forestomach tumors induced by 2-amino-3,4-dimethylimidazo[4,5-f]quinoline.
Journal: Molecular carcinogenesis19950101
Title: Function and localization of cytochromes P450 involved in the metabolic activation of food-derived heterocyclic amines.
Journal: Princess Takamatsu symposia19950101
Title: Studies on the carcinogenic and myocardial effects of 2-amino-3-methylimidazo [4,5-f] quinoline (IQ) in nonhuman primates.
Journal: Princess Takamatsu symposia19950101
Title: Genetic alterations in HCA-induced tumors.
Journal: Princess Takamatsu symposia19950101
Title: Chemopreventive effects of beta-carotene, alpha-tocopherol and five naturally occurring antioxidants on initiation of hepatocarcinogenesis by 2-amino-3-methylimidazo[4,5-f]quinoline in the rat.
Journal: Japanese journal of cancer research : Gann19941201
Title: Metabolic activation of heterocyclic amine food mutagens in the mammary gland of lactating Fischer 344 rats.
Journal: Cancer letters19940829
Title: Heterocyclic amines formed by cooking food: comparison of bioassay results with other chemicals in the Carcinogenic Potency Database.
Journal: Cancer letters19940815
Title: Dietary carcinogens and mammary carcinogenesis. Induction of rat mammary carcinomas by administration of heterocyclic amines in cooked foods.
Journal: Cancer19940801
Title: Metabolism of the food derived mutagen and carcinogen 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine (PhIP) by human liver microsomes.
Journal: Carcinogenesis19940601
Title: 2-Amino-3,4-dimethylimidazo[4,5-f]quinoline induces and inhibits cytochrome P450 from the IA subfamily in chick and rat hepatocytes.
Journal: Cancer research19920701
Title: Uroporphyrinogen oxidation catalyzed by reconstituted cytochrome P450IA2.
Journal: Archives of biochemistry and biophysics19920501
Title: Metabolism of food-derived heterocyclic amines in human and rabbit tissues by P4503A proteins in the presence of flavonoids.
Journal: Cancer research19920401
Title: Detection of a Ha-ras point mutation by polymerase chain reaction-single strand conformation polymorphism analysis in 2-amino-3,4-dimethylimidazo[4,5-f]quinoline-induced mouse forestomach tumors.
Journal: Cancer letters19920227
Title: Enhancement of GST-P positive liver cell foci development by combined treatment of rats with five heterocyclic amines at low doses.
Journal: Carcinogenesis19910501
Title: Mutational activation of c-Ha-ras gene in squamous cell carcinomas of rat Zymbal gland induced by carcinogenic heterocyclic amines.
Journal: Molecular carcinogenesis19910101
Title: Metabolism of 2-acetylaminofluorene and benzo(a)pyrene and activation of food-derived heterocyclic amine mutagens by human cytochromes P-450.
Journal: Cancer research19900601
Title: Carcinogenic potential of cooked food mutagens (IQ and MeIQ) in Wistar rats after short-term exposure.
Journal: Pharmacology & toxicology19891101
Title: Human liver microsomal cytochrome P-450 enzymes involved in the bioactivation of procarcinogens detected by umu gene response in Salmonella typhimurium TA 1535/pSK1002.
Journal: Cancer research19890615
Title: Induction of tumors in the Zymbal gland, oral cavity, colon, skin and mammary gland of F344 rats by a mutagenic compound, 2-amino-3,4-dimethylimidazo[4,5-f]quinoline.
Journal: Carcinogenesis19890301
Title: Streptozotocin-induced diabetes modulates the metabolic activation of chemical carcinogens.
Journal: Chemico-biological interactions19880101
Title: Induction of hepatocellular carcinoma and highly metastatic squamous cell carcinomas in the forestomach of mice by feeding 2-amino-3,4-dimethylimidazo[4,5-f]quinoline.
Journal: Carcinogenesis19861101
Title: Carcinogenicity in mice and rats of heterocyclic amines in cooked foods.
Journal: Environmental health perspectives19860801
Title: Carcinogenicities in mice and rats of IQ, MeIQ, and MeIQx.
Journal: Princess Takamatsu symposia19850101
