81039-77-2,MFCD02682895
Catalog No.:AA00G4PM

81039-77-2 | DESETHYLOXYBUTYNIN, HYDROCHLORIDE

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥95%
in stock  
$113.00   $79.00
- +
5mg
≥95%
in stock  
$502.00   $351.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00G4PM
Chemical Name:
DESETHYLOXYBUTYNIN, HYDROCHLORIDE
CAS Number:
81039-77-2
Molecular Formula:
C20H28ClNO3
Molecular Weight:
365.8942
MDL Number:
MFCD02682895
SMILES:
CCNCC#CCOC(=O)C(c1ccccc1)(C1CCCCC1)O.Cl
Properties
Computed Properties
 
Complexity:
452  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0  
Rotatable Bond Count:
7  
Undefined Atom Stereocenter Count:
1  
Undefined Bond Stereocenter Count:
0  

Literature

Title: Pharmacokinetics of oxybutynin chloride topical gel: effects of application site, baths, sunscreen and person-to-person transference.

Journal: Clinical drug investigation 20110101

Title: Enantioselective analysis of oxybutynin and N-desethyloxybutynin with application to an in vitro biotransformation study.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20081101

Title: The preparation and human muscarinic receptor profiling of oxybutynin and N-desethyloxybutynin enantiomers.

Journal: Medicinal chemistry (Shariqah (United Arab Emirates)) 20071101

Title: Binding activities by propiverine and its N-oxide metabolites of L-type calcium channel antagonist receptors in the rat bladder and brain.

Journal: Life sciences 20070606

Title: Pharmacokinetics/pharmacodynamics analysis of the relationship between the in vivo micturition pressure and receptor occupancy of (R)-oxybutynin and its metabolite in rats.

Journal: Biological & pharmaceutical bulletin 20070501

Title: Pharmacokinetics and pharmacodynamics of once-daily controlled-release oxybutynin and immediate-release oxybutynin.

Journal: Journal of clinical pharmacology 20070301

Title: Stereoselective pharmacokinetics of oxybutynin and N-desethyloxybutynin in vitro and in vivo.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20070101

Title: Transdermal oxybutynin in the treatment of overactive bladder.

Journal: Clinical interventions in aging 20060601

Title: Advantages for transdermal over oral oxybutynin to treat overactive bladder: Muscarinic receptor binding, plasma drug concentration, and salivary secretion.

Journal: The Journal of pharmacology and experimental therapeutics 20060301

Title: Muscarinic receptor binding, plasma concentration and inhibition of salivation after oral administration of a novel antimuscarinic agent, solifenacin succinate in mice.

Journal: British journal of pharmacology 20050501

Title: In vivo demonstration of muscarinic receptor binding activity of N-desethyl-oxybutynin, active metabolite of oxybutynin.

Journal: Life sciences 20050408

Title: [Effect of 4-ethylamino-2-butynyl(2-cyclohexyl-2-phenyl) glycolate, metabolite of oxybutynin, on intra-artery administered acetylcholine-induced urinary bladder contraction in anesthetized dogs].

Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20040501

Title: Effects of 4-ethylamino-2-butynyl(2-cyclohexyl-2-phenyl)glycolate hydrochloride, a metabolite of oxybutynin, on bladder specimens and rhythmic bladder contraction in rats in comparison with oxybutynin.

Journal: Journal of pharmacological sciences 20040201

Title: Oxybutynin extended-release: a review of its use in the management of overactive bladder.

Journal: Drugs 20040101

Title: Pharmacokinetics, metabolism, and saliva output during transdermal and extended-release oral oxybutynin administration in healthy subjects.

Journal: Mayo Clinic proceedings 20030601

Title: Sensitive determination of oxybutynin and desethyloxybutynin in dog plasma by LC-ESI/MS/MS.

Journal: Journal of pharmaceutical and biomedical analysis 20030226

Title: Transdermal oxybutynin: for overactive bladder.

Journal: Drugs & aging 20030101

Title: Transdermal oxybutynin. A viewpoint by Michael Chancellor.

Journal: Drugs & aging 20030101

Title: Transdermal oxybutynin. A viewpoint by Adrian Wagg.

Journal: Drugs & aging 20030101

Title: Binding study of desethyloxybutynin using high-performance frontal analysis method.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020225

Title: Pharmacokinetics, efficacy, and safety of intravesical formulation of oxybutynin in patients with detrusor overactivity.

Journal: Scandinavian journal of urology and nephrology 20020201

Title: Intravesical oxybutynin: mode of action assessed by passive diffusion and electromotive administration with pharmacokinetics of oxybutynin and N-desethyl oxybutynin.

Journal: The Journal of urology 20011201

Title: Pharmacokinetics of the R- and S-enantiomers of oxybutynin and N-desethyloxybutynin following oral and transdermal administration of the racemate in healthy volunteers.

Journal: Pharmaceutical research 20010701

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Tags:81039-77-2 Molecular Formula|81039-77-2 MDL|81039-77-2 SMILES|81039-77-2 DESETHYLOXYBUTYNIN, HYDROCHLORIDE
Catalog No.: AA00G4PM
81039-77-2,MFCD02682895
81039-77-2 | DESETHYLOXYBUTYNIN, HYDROCHLORIDE
Pack Size: 1mg
Purity: ≥95%
in stock
$113.00 $79.00
Pack Size: 5mg
Purity: ≥95%
in stock
$502.00 $351.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA00G4PM
Chemical Name: DESETHYLOXYBUTYNIN, HYDROCHLORIDE
CAS Number: 81039-77-2
Molecular Formula: C20H28ClNO3
Molecular Weight: 365.8942
MDL Number: MFCD02682895
SMILES: CCNCC#CCOC(=O)C(c1ccccc1)(C1CCCCC1)O.Cl
Properties
Complexity: 452  
Covalently-Bonded Unit Count: 2  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 25  
Hydrogen Bond Acceptor Count: 4  
Hydrogen Bond Donor Count: 3  
Isotope Atom Count: 0  
Rotatable Bond Count: 7  
Undefined Atom Stereocenter Count: 1  
Undefined Bond Stereocenter Count: 0  
Literature fold

Title: Pharmacokinetics of oxybutynin chloride topical gel: effects of application site, baths, sunscreen and person-to-person transference.

Journal: Clinical drug investigation20110101

Title: Enantioselective analysis of oxybutynin and N-desethyloxybutynin with application to an in vitro biotransformation study.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20081101

Title: The preparation and human muscarinic receptor profiling of oxybutynin and N-desethyloxybutynin enantiomers.

Journal: Medicinal chemistry (Shariqah (United Arab Emirates))20071101

Title: Binding activities by propiverine and its N-oxide metabolites of L-type calcium channel antagonist receptors in the rat bladder and brain.

Journal: Life sciences20070606

Title: Pharmacokinetics/pharmacodynamics analysis of the relationship between the in vivo micturition pressure and receptor occupancy of (R)-oxybutynin and its metabolite in rats.

Journal: Biological & pharmaceutical bulletin20070501

Title: Pharmacokinetics and pharmacodynamics of once-daily controlled-release oxybutynin and immediate-release oxybutynin.

Journal: Journal of clinical pharmacology20070301

Title: Stereoselective pharmacokinetics of oxybutynin and N-desethyloxybutynin in vitro and in vivo.

Journal: Xenobiotica; the fate of foreign compounds in biological systems20070101

Title: Transdermal oxybutynin in the treatment of overactive bladder.

Journal: Clinical interventions in aging20060601

Title: Advantages for transdermal over oral oxybutynin to treat overactive bladder: Muscarinic receptor binding, plasma drug concentration, and salivary secretion.

Journal: The Journal of pharmacology and experimental therapeutics20060301

Title: Muscarinic receptor binding, plasma concentration and inhibition of salivation after oral administration of a novel antimuscarinic agent, solifenacin succinate in mice.

Journal: British journal of pharmacology20050501

Title: In vivo demonstration of muscarinic receptor binding activity of N-desethyl-oxybutynin, active metabolite of oxybutynin.

Journal: Life sciences20050408

Title: [Effect of 4-ethylamino-2-butynyl(2-cyclohexyl-2-phenyl) glycolate, metabolite of oxybutynin, on intra-artery administered acetylcholine-induced urinary bladder contraction in anesthetized dogs].

Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica20040501

Title: Effects of 4-ethylamino-2-butynyl(2-cyclohexyl-2-phenyl)glycolate hydrochloride, a metabolite of oxybutynin, on bladder specimens and rhythmic bladder contraction in rats in comparison with oxybutynin.

Journal: Journal of pharmacological sciences20040201

Title: Oxybutynin extended-release: a review of its use in the management of overactive bladder.

Journal: Drugs20040101

Title: Pharmacokinetics, metabolism, and saliva output during transdermal and extended-release oral oxybutynin administration in healthy subjects.

Journal: Mayo Clinic proceedings20030601

Title: Sensitive determination of oxybutynin and desethyloxybutynin in dog plasma by LC-ESI/MS/MS.

Journal: Journal of pharmaceutical and biomedical analysis20030226

Title: Transdermal oxybutynin: for overactive bladder.

Journal: Drugs & aging20030101

Title: Transdermal oxybutynin. A viewpoint by Michael Chancellor.

Journal: Drugs & aging20030101

Title: Transdermal oxybutynin. A viewpoint by Adrian Wagg.

Journal: Drugs & aging20030101

Title: Binding study of desethyloxybutynin using high-performance frontal analysis method.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20020225

Title: Pharmacokinetics, efficacy, and safety of intravesical formulation of oxybutynin in patients with detrusor overactivity.

Journal: Scandinavian journal of urology and nephrology20020201

Title: Intravesical oxybutynin: mode of action assessed by passive diffusion and electromotive administration with pharmacokinetics of oxybutynin and N-desethyl oxybutynin.

Journal: The Journal of urology20011201

Title: Pharmacokinetics of the R- and S-enantiomers of oxybutynin and N-desethyloxybutynin following oral and transdermal administration of the racemate in healthy volunteers.

Journal: Pharmaceutical research20010701

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