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Title: Regulation of leucine-stimulated insulin secretion and glutamine metabolism in isolated rat islets.
Journal: The Journal of biological chemistry20030131
Title: Characterization of homoisocitrate dehydrogenase involved in lysine biosynthesis of an extremely thermophilic bacterium, Thermus thermophilus HB27, and evolutionary implication of beta-decarboxylating dehydrogenase.
Journal: The Journal of biological chemistry20030117
Title: Human mitochondrial and cytosolic branched-chain aminotransferases are cysteine S-conjugate beta-lyases, but turnover leads to inactivation.
Journal: Biochemical pharmacology20030115
Title: Mycobacterium tuberculosis ketopantoate hydroxymethyltransferase: tetrahydrofolate-independent hydroxymethyltransferase and enolization reactions with alpha-keto acids.
Journal: Biochemistry20030114
Title: Expression of monocarboxylic acid transporters (MCT) in brain cells. Implication for branched chain alpha-ketoacids transport in neurons.
Journal: Neurochemistry international20030101
Title: Leucine promotes glucose uptake in skeletal muscles of rats.
Journal: Biochemical and biophysical research communications20021220
Title: alpha-Ketoisocaproic acid regulates phosphorylation of intermediate filaments in postnatal rat cortical slices through ionotropic glutamatergic receptors.
Journal: Brain research. Developmental brain research20021215
Title: Role of blood cells in leucine kinetics across the human kidney.
Journal: American journal of physiology. Renal physiology20021201
Title: Kinetics of sequential metabolism from D-leucine to L-leucine via alpha-ketoisocaproic acid in rat.
Journal: Drug metabolism and disposition: the biological fate of chemicals20021201
Title: Insulin secretion induced by palmitate--a process fully dependent on glucose concentration.
Journal: Diabetes & metabolism20021201
Title: Possible involvement of phospholipase C and protein kinase C in stimulatory actions of L-leucine and its keto acid, alpha-ketoisocaproic acid, on protein synthesis in RLC-16 hepatocytes.
Journal: Cytotechnology20021101
Title: The stimulus-secretion coupling of amino acid-induced insulin release. Insulinotropic action of L-alanine.
Journal: Biochimica et biophysica acta20021010
Title: Inflammatory signals associated with hemodialysis.
Journal: Kidney international20021001
Title: Effect of supply of metabolizable protein on whole body and splanchnic leucine metabolism in lactating dairy cows.
Journal: Journal of dairy science20021001
Title: A continuous 96-well plate spectrophotometric assay for branched-chain amino acid aminotransferases.
Journal: Analytical biochemistry20020901
Title: Synthesis rate of muscle proteins, muscle functions, and amino acid kinetics in type 2 diabetes.
Journal: Diabetes20020801
Title: Short-term treatment with low doses of recombinant human GH stimulates lipolysis in visceral obese men.
Journal: The Journal of clinical endocrinology and metabolism20020701
Title: Crystallization and preliminary X-ray analysis of substrate complexes of leucine dehydrogenase from Thermoactinomyces intermedius.
Journal: Acta crystallographica. Section D, Biological crystallography20020601
Title: Effects of medium- and long-chain fatty acids on whole body leucine and glucose kinetics in man.
Journal: Metabolism: clinical and experimental20020601
Title: Effect of the branched-chain alpha-ketoacids accumulating in maple syrup urine disease on the high molecular weight neurofilament subunit (NF-H) in rat cerebral cortex.
Journal: Metabolic brain disease20020601
Title: Association of upregulated activity of K(ATP) channels with impaired insulin secretion in UCP1-expressing insulinoma cells.
Journal: The Journal of physiology20020501
Title: Large neutral amino acids auto exchange when infused by microdialysis into the rat brain: implication for maple syrup urine disease and phenylketonuria.
Journal: Neurochemistry international20020401
Title: Increased synthesis rate of fibrinogen as a basis for its elevated plasma levels in obese female adolescents.
Journal: American journal of physiology. Endocrinology and metabolism20020401
Title: Sequential extracts of human bone show differing collagen synthetic rates.
Journal: Biochemical Society transactions20020401
Title: Reduction in pancreatic transcription factor PDX-1 impairs glucose-stimulated insulin secretion.
Journal: The Journal of biological chemistry20020329
Title: Effects of cytochalasin B and D upon insulin release and pancreatic islet cell metabolism.
Journal: International journal of molecular medicine20020201
Title: Triggering of insulin release by a combination of cAMP signal and nutrients: an ATP-sensitive K+ channel-independent phenomenon.
Journal: Diabetes20020201
Title: Conversion of L-leucine to isovaleric acid by Propionibacterium freudenreichii TL 34 and ITGP23.
Journal: Applied and environmental microbiology20020201
Title: The antilipolytic agent 3,5-dimethylpyrazole inhibits insulin release in response to both nutrient secretagogues and cyclic adenosine monophosphate agonists in isolated rat islets.
Journal: Metabolism: clinical and experimental20020101
Title: Effect of preeclampsia in the mother on the leucine metabolism in the newborn infant.
Journal: Biology of the neonate20020101
Title: Protein turnover, lipolysis, and endogenous hormonal secretion in critically ill children.
Journal: Critical care medicine20020101
Title: Effects of leucine supplemented diet on intestinal absorption in tumor bearing pregnant rats.
Journal: BMC cancer20020101
Title: Comparison of the secretory properties of four insulin-secreting cell lines.
Journal: Endocrine research20020101
Title: Supplementing with beta-hydroxy-beta-methylbutyrate (HMB) to build and maintain muscle mass: a review.
Journal: Research communications in molecular pathology and pharmacology20020101
Title: Tissue-specific regulation of mitochondrial and cytoplasmic protein synthesis rates by insulin.
Journal: Diabetes20011201
Title: Phenotyping of individual pancreatic islets locates genetic defects in stimulus secretion coupling to Niddm1i within the major diabetes locus in GK rats.
Journal: Diabetes20011201
Title: Metabolic approach of absence seizures in a genetic model of absence epilepsy, the GAERS: study of the leucine-glutamate cycle.
Journal: Journal of neuroscience research20011201
Title: Recovery of function and mass of endogenous beta-cells in streptozotocin-induced diabetic rats treated with islet transplantation.
Journal: Biochemical and biophysical research communications20010914
Title: Laboratory approach to mitochondrial diseases.
Journal: Journal of physiology and biochemistry20010901
Title: Recovery of (13)CO(2) from infused [1-(13)C]leucine and [1,2-(13)C(2)]leucine in healthy humans.
Journal: American journal of physiology. Endocrinology and metabolism20010801
Title: Cytokine-mediated inhibition of ketogenesis is unrelated to nitric oxide or protein synthesis.
Journal: Clinical nutrition (Edinburgh, Scotland)20010801
Title: Psychrophilic valine dehydrogenase of the antarctic psychrophile, Cytophaga sp. KUC-1: purification, molecular characterization and expression.
Journal: European journal of biochemistry20010801
Title: Effects of dietary protein restriction and amino acids deficiency on protein metabolism in dogs.
Journal: Journal of animal physiology and animal nutrition20010801
Title: TPN-evoked dysfunction of islet lysosomal activity mediates impairment of glucose-stimulated insulin release.
Journal: American journal of physiology. Endocrinology and metabolism20010701
Title: Modulation of absence seizures by branched-chain amino acids: correlation with brain amino acid concentrations.
Journal: Neuroscience research20010701
Title: Structures of Escherichia coli branched-chain amino acid aminotransferase and its complexes with 4-methylvalerate and 2-methylleucine: induced fit and substrate recognition of the enzyme.
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Title: Leucine and its keto acid enhance the coordinated expression of genes for branched-chain amino acid catabolism in Arabidopsis under sugar starvation.
Journal: FEBS letters20010615
Title: Heat shock restores insulin secretion after injury by nitric oxide by maintaining glucokinase activity in rat islets.
Journal: Biochemical and biophysical research communications20010601
Title: Protein metabolism in clinically stable adult cystic fibrosis patients with abnormal glucose tolerance.
Journal: Diabetes20010601
Title: Amino acid, glucose, and lipid kinetics after palliative resection in a patient with glucagonoma syndrome.
Journal: Metabolism: clinical and experimental20010601
Title: Alteration of the co-substrate selectivity of deacetoxycephalosporin C synthase. The role of arginine 258.
Journal: The Journal of biological chemistry20010525
Title: Proteasomal activation mediates down-regulation of inositol 1,4,5-trisphosphate receptor and calcium mobilization in rat pancreatic islets.
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Title: Whole-body L-leucine oxidation in patients with variant form of maple syrup urine disease.
Journal: Pediatric research20010501
Title: Recombinant tyrosine aminotransferase from Trypanosoma cruzi: structural characterization and site directed mutagenesis of a broad substrate specificity enzyme.
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Title: Pharmacological evidence that alpha-ketoisovaleric acid induces convulsions through GABAergic and glutamatergic mechanisms in rats.
Journal: Brain research20010309
Title: Specific desensitization of sulfonylurea- but not imidazoline-induced insulin release after prolonged tolbutamide exposure.
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Title: Gas chromatographic-mass spectrometric determination of alpha-ketoisocaproic acid and [2H7]alpha-ketoisocaproic acid in plasma after derivatization with N-phenyl-1,2-phenylenediamine.
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Title: Defective stimulus-secretion coupling in islets of Psammomys obesus, an animal model for type 2 diabetes.
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Title: Inosine-5'-monophosphate dehydrogenase is required for mitogenic competence of transformed pancreatic beta cells.
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Title: Enhanced flavour formation by combination of selected lactococci from industrial and artisanal origin with focus on completion of a metabolic pathway.
Journal: Journal of applied microbiology20010101
Title: A multiple infusion start time (MIST) protocol for stable isotope studies of fetal blood.
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Title: Effect of starvation on branched-chain alpha-keto acid dehydrogenase activity in rat heart and skeletal muscle.
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Title: Metabolism of branched-chain amino acids in starved rats: the role of hepatic tissue.
Journal: Physiological research20010101
Title: Differential acute and long term actions of succinic acid monomethyl ester exposure on insulin-secreting BRIN-BD11 cells.
Journal: International journal of experimental diabetes research20010101
Title: Pyruvate decarboxylase encoded by the PDC1 gene contributes, at least partially, to the decarboxylation of alpha-ketoisocaproate for isoamyl alcohol formation in Saccharomyces cerevisiae.
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