82854-37-3,MFCD00075695
Catalog No.:AA00G2QU

82854-37-3 | Echinacoside

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Purity
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1mg
98% by HPLC
in stock  
$77.00   $54.00
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5mg
≥95%
in stock  
$89.00   $62.00
- +
10mg
≥95%
in stock  
$156.00   $109.00
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100mg
98+%
in stock  
$236.00   $166.00
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  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00G2QU
Chemical Name:
Echinacoside
CAS Number:
82854-37-3
Molecular Formula:
C35H46O20
Molecular Weight:
786.7277
MDL Number:
MFCD00075695
SMILES:
OC[C@H]1O[C@@H](OC[C@H]2O[C@@H](OCCc3ccc(c(c3)O)O)[C@@H]([C@H]([C@@H]2OC(=O)/C=C/c2ccc(c(c2)O)O)O[C@@H]2O[C@@H](C)[C@@H]([C@H]([C@H]2O)O)O)O)[C@@H]([C@H]([C@@H]1O)O)O
Properties
Computed Properties
 
Complexity:
1230  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
15  
Defined Bond Stereocenter Count:
1  
Formal Charge:
0  
Heavy Atom Count:
55  
Hydrogen Bond Acceptor Count:
20  
Hydrogen Bond Donor Count:
12  
Isotope Atom Count:
0  
Rotatable Bond Count:
14  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
-2.1  

Synonyms
 
854E373  
Literature

Title: Echinacoside Protects Against MPP(+)-Induced Neuronal Apoptosis via ROS/ATF3/CHOP Pathway Regulation.

Journal: Neuroscience bulletin 20160801

Title: Transient exposure to echinacoside is sufficient to activate Trk signaling and protect neuronal cells from rotenone.

Journal: Journal of neurochemistry 20130201

Title: Phenylpropanoid glycosides from plant cell cultures induce heme oxygenase 1 gene expression in a human keratinocyte cell line by affecting the balance of NRF2 and BACH1 transcription factors.

Journal: Chemico-biological interactions 20120830

Title: Selective protection of nigral dopaminergic neurons by echinacoside in a rat model of Parkinson disease induced by rotenone.

Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20120701

Title: Echinacoside stimulates cell proliferation and prevents cell apoptosis in intestinal epithelial MODE-K cells by up-regulation of transforming growth factor-β1 expression.

Journal: Journal of pharmacological sciences 20120101

Title: HPLC determination of antilipoxygenase activity of a water infusion of Ligustrum vulgare L. leaves and some of its constituents.

Journal: Molecules (Basel, Switzerland) 20110928

Title: Effects of 2-aminoindan-2-phosphonic acid treatment on the accumulation of salidroside and four phenylethanoid glycosides in suspension cell culture of Cistanche deserticola.

Journal: Plant cell reports 20110401

Title: Production of acteoside from Cistanche tubulosa by β-glucosidase.

Journal: Pakistan journal of pharmaceutical sciences 20110401

Title: Phytochemical and immunomodulatory properties of an Echinacea laevigata (Asteraceae) tincture.

Journal: Journal of alternative and complementary medicine (New York, N.Y.) 20110401

Title: Separation and purification of echinacoside from Penstemon barbatus (Can.) Roth by recycling high-speed counter-current chromatography.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20101015

Title: Inhibitory effect of acteoside isolated from Cistanche tubulosa on chemical mediator release and inflammatory cytokine production by RBL-2H3 and KU812 cells.

Journal: Planta medica 20101001

Title: Neurotrophic and neurorescue effects of Echinacoside in the subacute MPTP mouse model of Parkinson's disease.

Journal: Brain research 20100730

Title: Suppression of nitric oxide implicated in the protective effect of echinacoside on H2O2-induced PC12 cell injury.

Journal: Natural product communications 20100401

Title: An approach to identifying sequential metabolites of a typical phenylethanoid glycoside, echinacoside, based on liquid chromatography-ion trap-time of flight mass spectrometry analysis.

Journal: Talanta 20091215

Title: Protective effects of echinacoside, one of the phenylethanoid glycosides, on H(2)O(2)-induced cytotoxicity in PC12 cells.

Journal: Planta medica 20091101

Title: Echinacoside retards cellular senescence of human fibroblastic cells MRC-5.

Journal: Die Pharmazie 20091101

Title: Echinacoside elicits endothelium-dependent relaxation in rat aortic rings via an NO-cGMP pathway.

Journal: Planta medica 20091001

Title: Mesophyll distribution of 'antioxidant' flavonoid glycosides in Ligustrum vulgare leaves under contrasting sunlight irradiance.

Journal: Annals of botany 20091001

Title: A sensitive and specific liquid chromatography/tandem mass spectrometry method for determination of echinacoside and its pharmacokinetic application in rats.

Journal: Biomedical chromatography : BMC 20090601

Title: Metabolism of echinacoside, a good antioxidant, in rats: isolation and identification of its biliary metabolites.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20090201

Title: [Research progress on pharmacological activities of echinacoside].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090201

Title: [Effects of precursor feeding and fungal elicitors on secondary metabolits in cell suspension culture of Cistanche deserticola].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20090201

Title: [Preliminary study on variation pattern of Cistanche deserticola].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20081001

Title: Echinacoside prevents the striatal extracellular levels of monoamine neurotransmitters from diminution in 6-hydroxydopamine lesion rats.

Journal: Journal of ethnopharmacology 20071203

Title: [Study on secondary metabolic organ of echinacoside in herbs of Cistanche tubulosa].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20071201

Title: [Inoculation experiments of Cistanche tubulosa on 8 introduced Tamarix species].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20071001

Title: [Study on reproduction biology of Cistanche deserticola--seedling emergence and flowering].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070901

Title: Protection of echinacoside against acute lung injury caused by oleic acid in rats.

Journal: Free radical research 20070701

Title: [Study on processing method of Cistanche tubulosa].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070701

Title: Neuroprotective effects of echinacoside in the mouse MPTP model of Parkinson's disease.

Journal: European journal of pharmacology 20070614

Title: Protective effects of echinacoside on carbon tetrachloride-induced hepatotoxicity in rats.

Journal: Toxicology 20070322

Title: Determination of echinacoside in rat serum by reversed-phase high-performance liquid chromatography with ultraviolet detection and its application to pharmacokinetics and bioavailability.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20061205

Title: Investigation of anti-hyaluronidase treatment on vocal fold wound healing.

Journal: Journal of voice : official journal of the Voice Foundation 20060901

Title: [Studied of dry matter accumulation and echinacoside content of Cistanche tubulosa in Huabei plain].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060801

Title: Synergistic antioxidative effects of alkamides, caffeic acid derivatives, and polysaccharide fractions from Echinacea purpurea on in vitro oxidation of human low-density lipoproteins.

Journal: Journal of agricultural and food chemistry 20051130

Title: [The determination of echinacoside and acteoside in herbs of Cistanche tubulosa].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050601

Title: Echinacoside rescues the SHSY5Y neuronal cells from TNFalpha-induced apoptosis.

Journal: European journal of pharmacology 20041128

Title: [Determination of phenylethanoid glycosides from Cistanche deserticola in spring and autumn with LC-MS].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20040301

Title: Improvement of phenylethanoid glycosides production by a fungal elicitor in cell suspension culture of Cistanche deserticola.

Journal: Biotechnology letters 20030901

Title: Evaluation of antioxidant activity of some natural polyphenolic compounds using the Briggs-Rauscher reaction method.

Journal: Journal of agricultural and food chemistry 20021218

Title: [Determination of echinacoside in congrong spirit by reversed-phase high performance liquid chromatography].

Journal: Se pu = Chinese journal of chromatography 20021101

Title: Rapid and non-destructive determination of the echinacoside content in Echinacea roots by ATR-IR and NIR spectroscopy.

Journal: Planta medica 20021001

Title: Simultaneous analysis of alkamides and caffeic acid derivatives for the identification of Echinacea purpurea, Echinacea angustifolia, Echinacea pallida and Parthenium integrifolium roots.

Journal: Planta medica 20020601

Title: [Metabolic regulation of phenylethanoid glycosides from Herba cistanches in dogs' gastrointestine].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20010601

Title: [Separation of echinacoside by reversed-phase preparative high performance liquid chromatography].

Journal: Se pu = Chinese journal of chromatography 20010501

Title: Li X, et al. Echinacoside ameliorates D-galactosamine plus lipopolysaccharide-induced acute liver injury in mice via inhibition of apoptosis and inflammation. Scand J Gastroenterol. 2014 Aug;49(8):993-1000.

Title: Tang C, et al. Echinacoside inhibits breast cancer cells by suppressing the Wnt/β-catenin signaling pathway. Biochem Biophys Res Commun. 2020 Mar 19. pii: S0006-291X(20)30530-1.

Title: Li F, et al. Antiosteoporotic activity of echinacoside in ovariectomized rats. Phytomedicine. 2013 Apr 15;20(6):549-57.

Title: Zhang D, et al. Echinacoside inhibits amyloid fibrillization of HEWL and protects against Aβ-induced neurotoxicity. Int J Biol Macromol. 2014 Sep 2;72C:243-253.

Title: Zhu M, et al. Transient exposure to echinacoside is sufficient to activate Trk signaling and protect neuronal cells from rotenone. J Neurochem. 2013 Feb;124(4):571-80.

Title: Li F, et al. Echinacoside promotes bone regeneration by increasing OPG/RANKL ratio in MC3T3-E1 cells. Fitoterapia. 2012 Dec;83(8):1443-50.

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SDS
Tags:82854-37-3 Molecular Formula|82854-37-3 MDL|82854-37-3 SMILES|82854-37-3 Echinacoside
Catalog No.: AA00G2QU
82854-37-3,MFCD00075695
82854-37-3 | Echinacoside
Pack Size: 1mg
Purity: 98% by HPLC
in stock
$77.00 $54.00
Pack Size: 5mg
Purity: ≥95%
in stock
$89.00 $62.00
Pack Size: 10mg
Purity: ≥95%
in stock
$156.00 $109.00
Pack Size: 100mg
Purity: 98+%
in stock
$236.00 $166.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA00G2QU
Chemical Name: Echinacoside
CAS Number: 82854-37-3
Molecular Formula: C35H46O20
Molecular Weight: 786.7277
MDL Number: MFCD00075695
SMILES: OC[C@H]1O[C@@H](OC[C@H]2O[C@@H](OCCc3ccc(c(c3)O)O)[C@@H]([C@H]([C@@H]2OC(=O)/C=C/c2ccc(c(c2)O)O)O[C@@H]2O[C@@H](C)[C@@H]([C@H]([C@H]2O)O)O)O)[C@@H]([C@H]([C@@H]1O)O)O
Properties
Complexity: 1230  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 15  
Defined Bond Stereocenter Count: 1  
Formal Charge: 0  
Heavy Atom Count: 55  
Hydrogen Bond Acceptor Count: 20  
Hydrogen Bond Donor Count: 12  
Isotope Atom Count: 0  
Rotatable Bond Count: 14  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: -2.1  
38: 854E373  
Literature fold

Title: Echinacoside Protects Against MPP(+)-Induced Neuronal Apoptosis via ROS/ATF3/CHOP Pathway Regulation.

Journal: Neuroscience bulletin20160801

Title: Transient exposure to echinacoside is sufficient to activate Trk signaling and protect neuronal cells from rotenone.

Journal: Journal of neurochemistry20130201

Title: Phenylpropanoid glycosides from plant cell cultures induce heme oxygenase 1 gene expression in a human keratinocyte cell line by affecting the balance of NRF2 and BACH1 transcription factors.

Journal: Chemico-biological interactions20120830

Title: Selective protection of nigral dopaminergic neurons by echinacoside in a rat model of Parkinson disease induced by rotenone.

Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine20120701

Title: Echinacoside stimulates cell proliferation and prevents cell apoptosis in intestinal epithelial MODE-K cells by up-regulation of transforming growth factor-β1 expression.

Journal: Journal of pharmacological sciences20120101

Title: HPLC determination of antilipoxygenase activity of a water infusion of Ligustrum vulgare L. leaves and some of its constituents.

Journal: Molecules (Basel, Switzerland)20110928

Title: Effects of 2-aminoindan-2-phosphonic acid treatment on the accumulation of salidroside and four phenylethanoid glycosides in suspension cell culture of Cistanche deserticola.

Journal: Plant cell reports20110401

Title: Production of acteoside from Cistanche tubulosa by β-glucosidase.

Journal: Pakistan journal of pharmaceutical sciences20110401

Title: Phytochemical and immunomodulatory properties of an Echinacea laevigata (Asteraceae) tincture.

Journal: Journal of alternative and complementary medicine (New York, N.Y.)20110401

Title: Separation and purification of echinacoside from Penstemon barbatus (Can.) Roth by recycling high-speed counter-current chromatography.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20101015

Title: Inhibitory effect of acteoside isolated from Cistanche tubulosa on chemical mediator release and inflammatory cytokine production by RBL-2H3 and KU812 cells.

Journal: Planta medica20101001

Title: Neurotrophic and neurorescue effects of Echinacoside in the subacute MPTP mouse model of Parkinson's disease.

Journal: Brain research20100730

Title: Suppression of nitric oxide implicated in the protective effect of echinacoside on H2O2-induced PC12 cell injury.

Journal: Natural product communications20100401

Title: An approach to identifying sequential metabolites of a typical phenylethanoid glycoside, echinacoside, based on liquid chromatography-ion trap-time of flight mass spectrometry analysis.

Journal: Talanta20091215

Title: Protective effects of echinacoside, one of the phenylethanoid glycosides, on H(2)O(2)-induced cytotoxicity in PC12 cells.

Journal: Planta medica20091101

Title: Echinacoside retards cellular senescence of human fibroblastic cells MRC-5.

Journal: Die Pharmazie20091101

Title: Echinacoside elicits endothelium-dependent relaxation in rat aortic rings via an NO-cGMP pathway.

Journal: Planta medica20091001

Title: Mesophyll distribution of 'antioxidant' flavonoid glycosides in Ligustrum vulgare leaves under contrasting sunlight irradiance.

Journal: Annals of botany20091001

Title: A sensitive and specific liquid chromatography/tandem mass spectrometry method for determination of echinacoside and its pharmacokinetic application in rats.

Journal: Biomedical chromatography : BMC20090601

Title: Metabolism of echinacoside, a good antioxidant, in rats: isolation and identification of its biliary metabolites.

Journal: Drug metabolism and disposition: the biological fate of chemicals20090201

Title: [Research progress on pharmacological activities of echinacoside].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20090201

Title: [Effects of precursor feeding and fungal elicitors on secondary metabolits in cell suspension culture of Cistanche deserticola].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials20090201

Title: [Preliminary study on variation pattern of Cistanche deserticola].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20081001

Title: Echinacoside prevents the striatal extracellular levels of monoamine neurotransmitters from diminution in 6-hydroxydopamine lesion rats.

Journal: Journal of ethnopharmacology20071203

Title: [Study on secondary metabolic organ of echinacoside in herbs of Cistanche tubulosa].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20071201

Title: [Inoculation experiments of Cistanche tubulosa on 8 introduced Tamarix species].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20071001

Title: [Study on reproduction biology of Cistanche deserticola--seedling emergence and flowering].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20070901

Title: Protection of echinacoside against acute lung injury caused by oleic acid in rats.

Journal: Free radical research20070701

Title: [Study on processing method of Cistanche tubulosa].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20070701

Title: Neuroprotective effects of echinacoside in the mouse MPTP model of Parkinson's disease.

Journal: European journal of pharmacology20070614

Title: Protective effects of echinacoside on carbon tetrachloride-induced hepatotoxicity in rats.

Journal: Toxicology20070322

Title: Determination of echinacoside in rat serum by reversed-phase high-performance liquid chromatography with ultraviolet detection and its application to pharmacokinetics and bioavailability.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20061205

Title: Investigation of anti-hyaluronidase treatment on vocal fold wound healing.

Journal: Journal of voice : official journal of the Voice Foundation20060901

Title: [Studied of dry matter accumulation and echinacoside content of Cistanche tubulosa in Huabei plain].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20060801

Title: Synergistic antioxidative effects of alkamides, caffeic acid derivatives, and polysaccharide fractions from Echinacea purpurea on in vitro oxidation of human low-density lipoproteins.

Journal: Journal of agricultural and food chemistry20051130

Title: [The determination of echinacoside and acteoside in herbs of Cistanche tubulosa].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20050601

Title: Echinacoside rescues the SHSY5Y neuronal cells from TNFalpha-induced apoptosis.

Journal: European journal of pharmacology20041128

Title: [Determination of phenylethanoid glycosides from Cistanche deserticola in spring and autumn with LC-MS].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials20040301

Title: Improvement of phenylethanoid glycosides production by a fungal elicitor in cell suspension culture of Cistanche deserticola.

Journal: Biotechnology letters20030901

Title: Evaluation of antioxidant activity of some natural polyphenolic compounds using the Briggs-Rauscher reaction method.

Journal: Journal of agricultural and food chemistry20021218

Title: [Determination of echinacoside in congrong spirit by reversed-phase high performance liquid chromatography].

Journal: Se pu = Chinese journal of chromatography20021101

Title: Rapid and non-destructive determination of the echinacoside content in Echinacea roots by ATR-IR and NIR spectroscopy.

Journal: Planta medica20021001

Title: Simultaneous analysis of alkamides and caffeic acid derivatives for the identification of Echinacea purpurea, Echinacea angustifolia, Echinacea pallida and Parthenium integrifolium roots.

Journal: Planta medica20020601

Title: [Metabolic regulation of phenylethanoid glycosides from Herba cistanches in dogs' gastrointestine].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica20010601

Title: [Separation of echinacoside by reversed-phase preparative high performance liquid chromatography].

Journal: Se pu = Chinese journal of chromatography20010501

Title: Li X, et al. Echinacoside ameliorates D-galactosamine plus lipopolysaccharide-induced acute liver injury in mice via inhibition of apoptosis and inflammation. Scand J Gastroenterol. 2014 Aug;49(8):993-1000.

Title: Tang C, et al. Echinacoside inhibits breast cancer cells by suppressing the Wnt/β-catenin signaling pathway. Biochem Biophys Res Commun. 2020 Mar 19. pii: S0006-291X(20)30530-1.

Title: Li F, et al. Antiosteoporotic activity of echinacoside in ovariectomized rats. Phytomedicine. 2013 Apr 15;20(6):549-57.

Title: Zhang D, et al. Echinacoside inhibits amyloid fibrillization of HEWL and protects against Aβ-induced neurotoxicity. Int J Biol Macromol. 2014 Sep 2;72C:243-253.

Title: Zhu M, et al. Transient exposure to echinacoside is sufficient to activate Trk signaling and protect neuronal cells from rotenone. J Neurochem. 2013 Feb;124(4):571-80.

Title: Li F, et al. Echinacoside promotes bone regeneration by increasing OPG/RANKL ratio in MC3T3-E1 cells. Fitoterapia. 2012 Dec;83(8):1443-50.

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