83-49-8,MFCD00003681
Catalog No.:AA0038C5

83-49-8 | Hyodeoxycholic acid

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Purity
Availability
Price(USD)
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1g
95%
in stock  
$32.00   $23.00
- +
5g
≥ 98% (Assay by titration)
in stock  
$61.00   $43.00
- +
25g
≥ 98% (Assay by titration)
in stock  
$96.00   $67.00
- +
100g
≥ 98% (Assay by titration)
in stock  
$202.00   $142.00
- +
250g
≥ 98% (Assay by titration)
in stock  
$338.00   $237.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA0038C5
Chemical Name:
Hyodeoxycholic acid
CAS Number:
83-49-8
Molecular Formula:
C24H40O4
Molecular Weight:
392.5720
MDL Number:
MFCD00003681
SMILES:
OC1CC[C@]2(C(C1)CC([C@@H]1[C@@H]2CC[C@]2([C@H]1CC[C@@H]2[C@@H](CCC(=O)O)C)C)O)C
Properties
Computed Properties
 
Complexity:
605  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
10  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
28  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0  
Rotatable Bond Count:
4  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
4.9  

Literature

Title: 11β-Hydroxysteroid dehydrogenase-1 is involved in bile acid homeostasis by modulating fatty acid transport protein-5 in the liver of mice.

Journal: Molecular metabolism 20140801

Title: Human UDP-glucuronosyltransferases: feedback loops between substrates and ligands of their transcription factors.

Journal: Biochemical pharmacology 20121015

Title: BASIC--a bile acid-sensitive ion channel highly expressed in bile ducts.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20121001

Title: Gender, but not CYP7A1 or SLCO1B1 polymorphism, affects the fasting plasma concentrations of bile acids in human beings.

Journal: Basic & clinical pharmacology & toxicology 20120301

Title: A tandem mass spectrometric study of bile acids: interpretation of fragmentation pathways and differentiation of steroid isomers.

Journal: Steroids 20120201

Title: Gender-divergent profile of bile acid homeostasis during aging of mice.

Journal: PloS one 20120101

Title: Dysfunction of organic anion transporting polypeptide 1a1 alters intestinal bacteria and bile acid metabolism in mice.

Journal: PloS one 20120101

Title: Effects of human and porcine bile on the proteome of Helicobacter hepaticus.

Journal: Proteome science 20120101

Title: Refined Qingkailing Protects MCAO Mice from Endoplasmic Reticulum Stress-Induced Apoptosis with a Broad Time Window.

Journal: Evidence-based complementary and alternative medicine : eCAM 20120101

Title: Chinese medicine injection qingkailing for treatment of acute ischemia stroke: a systematic review of randomized controlled trials.

Journal: Evidence-based complementary and alternative medicine : eCAM 20120101

Title: A novel 'target constituent knock-out' strategy coupled with TLC, UPLC-ELSD and microcalorimetry for preliminary screening of antibacterial constituents in Calculus bovis.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111115

Title: Inhibition of human UGT2B7 gene expression in transgenic mice by the constitutive androstane receptor.

Journal: Molecular pharmacology 20110601

Title: Regulated phosphorylation of a major UDP-glucuronosyltransferase isozyme by tyrosine kinases dictates endogenous substrate selection for detoxification.

Journal: The Journal of biological chemistry 20110114

Title: Differentiation of various traditional Chinese medicines derived from animal bile and gallstone: simultaneous determination of bile acids by liquid chromatography coupled with triple quadrupole mass spectrometry.

Journal: Journal of chromatography. A 20110107

Title: Diurnal variations of mouse plasma and hepatic bile acid concentrations as well as expression of biosynthetic enzymes and transporters.

Journal: PloS one 20110101

Title: Profiling circulating and urinary bile acids in patients with biliary obstruction before and after biliary stenting.

Journal: PloS one 20110101

Title: Voluntary wheel running exercise and dietary lactose concomitantly reduce proportion of secondary bile acids in rat feces.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20100901

Title: Chemical genetic screen identifies lithocholic acid as an anti-aging compound that extends yeast chronological life span in a TOR-independent manner, by modulating housekeeping longevity assurance processes.

Journal: Aging 20100701

Title: Regulation of bile acid synthesis by fat-soluble vitamins A and D.

Journal: The Journal of biological chemistry 20100507

Title: Identification of human UGT2B7 as the major isoform involved in the O-glucuronidation of chloramphenicol.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20100301

Title: Liver X receptor agonist methyl-3β-hydroxy-5α,6α-epoxycholanate attenuates atherosclerosis in apolipoprotein E knockout mice without increasing plasma triglyceride.

Journal: Pharmacology 20100101

Title: Challenges predicting ligand-receptor interactions of promiscuous proteins: the nuclear receptor PXR.

Journal: PLoS computational biology 20091201

Title: Consumption of some polyphenols reduces fecal deoxycholic acid and lithocholic acid, the secondary bile acids of risk factors of colon cancer.

Journal: Journal of agricultural and food chemistry 20090923

Title: 3-ketocholanoic acid is the major in vitro human hepatic microsomal metabolite of lithocholic acid.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20090901

Title: Serum bile acid profiling reflects enterohepatic detoxification state and intestinal barrier function in inflammatory bowel disease.

Journal: World journal of gastroenterology 20090707

Title: Improved analysis of bile acids in tissues and intestinal contents of rats using LC/ESI-MS.

Journal: Journal of lipid research 20090101

Title: Bear bile: dilemma of traditional medicinal use and animal protection.

Journal: Journal of ethnobiology and ethnomedicine 20090101

Title: The inhibitory effects of cholalic acid and hyodeoxycholalic acid on the expression of TNFalpha and IL-1beta after cerebral ischemia in rats.

Journal: Archives of pharmacal research 20090101

Title: Regulation of sulfotransferase and UDP-glucuronosyltransferase gene expression by the PPARs.

Journal: PPAR research 20090101

Title: Novel polymorphic human UDP-glucuronosyltransferase 2A3: cloning, functional characterization of enzyme variants, comparative tissue expression, and gene induction.

Journal: Molecular pharmacology 20080901

Title: Novel potent and selective bile acid derivatives as TGR5 agonists: biological screening, structure-activity relationships, and molecular modeling studies.

Journal: Journal of medicinal chemistry 20080327

Title: Biotransformation of lithocholic acid by rat hepatic microsomes: metabolite analysis by liquid chromatography/mass spectrometry.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20080201

Title: Use of selected chemical markers in combination with a multiple regression model to assess the contribution of domesticated animal sources of fecal pollution in the environment.

Journal: Chemosphere 20071101

Title: [Determination of chyodeoxycholic acid in Bile Arisaema by HPLC-ELSD].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070801

Title: Comparative study on major bioactive components in natural, artificial and in-vitro cultured Calculus Bovis.

Journal: Chemical & pharmaceutical bulletin 20070101

Title: Simultaneous determination of geniposide, baicalin, cholic acid and hyodeoxycholic acid in rat serum for the pharmacokinetic investigations by high performance liquid chromatography-tandem mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060914

Title: 3alpha-6alpha-Dihydroxy-7alpha-fluoro-5beta-cholanoate (UPF-680), physicochemical and physiological properties of a new fluorinated bile acid that prevents 17alpha-ethynyl-estradiol-induced cholestasis in rats.

Journal: Toxicology and applied pharmacology 20060715

Title: Role for enhanced faecal excretion of bile acid in hydroxysteroid sulfotransferase-mediated protection against lithocholic acid-induced liver toxicity.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20060701

Title: Determination of three bile acids in artificial Calculus Bovis and its medicinal preparations by micellar electrokinetic capillary electrophoresis.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060606

Title: Mice lacking Mrp3 (Abcc3) have normal bile salt transport, but altered hepatic transport of endogenous glucuronides.

Journal: Journal of hepatology 20060401

Title: Simultaneous determination of nine components in Qingkailing injection by HPLC/ELSD/DAD and its application to the quality control.

Journal: Journal of pharmaceutical and biomedical analysis 20060303

Title: Enzymatic production of bile Acid glucuronides used as analytical standards for liquid chromatography-mass spectrometry analyses.

Journal: Molecular pharmaceutics 20060101

Title: Resistance to ursodeoxycholic acid-induced growth arrest can also result in resistance to deoxycholic acid-induced apoptosis and increased tumorgenicity.

Journal: BMC cancer 20060101

Title: Isolation and determination of bile acids.

Journal: European journal of drug metabolism and pharmacokinetics 20060101

Title: Simultaneous determination of major bioactive components in Qingkailing injection by high-performance liquid chromatography with evaporative light scattering detection.

Journal: Chemical & pharmaceutical bulletin 20051101

Title: [Simultaneous determination of five groups of components in qingkailing injection by high performance liquid chromatography with photo diode array detector and evaporative light scattering detector].

Journal: Se pu = Chinese journal of chromatography 20050901

Title: Interfacial properties of most monofluorinated bile acids deviate markedly from the natural congeners: studies with the Langmuir-Pockels surface balance.

Journal: Journal of lipid research 20050301

Title: Effect of dried plums on colon cancer risk factors in rats.

Journal: Nutrition and cancer 20050101

Title: Identification of UGT2B9*2 and UGT2B33 isolated from female rhesus monkey liver.

Journal: Archives of biochemistry and biophysics 20040601

Title: Effects of ileo-rectal anastomosis on cholesterol metabolism in pigs fed either casein or extruded soya beans.

Journal: The British journal of nutrition 20040501

Title: [Study on extraction technique of HDCA].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20040501

Title: UDP-glucuronosyltransferase and sulfotransferase polymorphisms, sex hormone concentrations, and tumor receptor status in breast cancer patients.

Journal: Breast cancer research : BCR 20040101

Title: Fluorescence resonance energy transfer in a novel cyclodextrin-peptide conjugate for detecting steroid molecules.

Journal: Bioorganic & medicinal chemistry letters 20031215

Title: Substrate specificities of rat oatp1 and ntcp: implications for hepatic organic anion uptake.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20031101

Title: Steroids in the intestinal tract of rats are affected by dietary-fibre-rich barley-based diets.

Journal: The British journal of nutrition 20031101

Title: Peroxisome proliferator-activated receptor alpha induces hepatic expression of the human bile acid glucuronidating UDP-glucuronosyltransferase 2B4 enzyme.

Journal: The Journal of biological chemistry 20030829

Title: Glucosidation of hyodeoxycholic acid by UDP-glucuronosyltransferase 2B7.

Journal: Biochemical pharmacology 20030201

Title: The cytotoxicity of hydrophobic bile acids is ameliorated by more hydrophilic bile acids in intestinal cell lines IEC-6 and Caco-2.

Journal: Oncology reports 20030101

Title: Dietary bile acids inhibit potentially elemental diet-induced small intestinal atrophy in rats.

Journal: International journal of molecular medicine 20021101

Title: [Study on effect of qingkailing injection and its active principle in inducing cell apoptosis in human acute promyelocytic leukemia].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20011101

Title: Hyodeoxycholic acid efficiently suppresses atherosclerosis formation and plasma cholesterol levels in mice.

Journal: Journal of lipid research 20010801

Title: Effect of bile salts on colonic mucus secretion in isolated vascularly perfused rat colon.

Journal: Digestive diseases and sciences 20010601

Title: Hydrophilic and hydrophobic bile acids exhibit different cytotoxicities through cytolysis, interleukin-8 synthesis and apoptosis in the intestinal epithelial cell lines. IEC-6 and Caco-2 cells.

Journal: Scandinavian journal of gastroenterology 20010501

Title: UGT2B23, a novel uridine diphosphate-glucuronosyltransferase enzyme expressed in steroid target tissues that conjugates androgen and estrogen metabolites.

Journal: Endocrinology 19991201

Title: Reinduction of the hypnotic effects of thiopental with NSAIDs by decreasing thiopental plasma protein binding in humans.

Journal: Acta anaesthesiologica Scandinavica 19930401

Title: Complementary deoxyribonucleic acid cloning and expression of a human liver uridine diphosphate-glucuronosyltransferase glucuronidating carboxylic acid-containing drugs.

Journal: The Journal of pharmacology and experimental therapeutics 19930101

Title: Isolation and characterization of hyodeoxycholic-acid: UDP-glucuronosyltransferase from human liver.

Journal: European journal of biochemistry 19910901

Title: Sato H, et al. Novel potent and selective bile acid derivatives as TGR5 agonists: biological screening, structure-activity relationships, and molecular modeling studies. J Med Chem. 2008 Mar 27;51(6):1831-41.

Title: Shih DM, et al. Hyodeoxycholic acid improves HDL function and inhibits atherosclerotic lesion formation in LDLR-knockout mice. FASEB J. 2013 Sep;27(9):3805-17.

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Tags:83-49-8 Molecular Formula|83-49-8 MDL|83-49-8 SMILES|83-49-8 Hyodeoxycholic acid
Catalog No.: AA0038C5
83-49-8,MFCD00003681
83-49-8 | Hyodeoxycholic acid
Pack Size: 1g
Purity: 95%
in stock
$32.00 $23.00
Pack Size: 5g
Purity: ≥ 98% (Assay by titration)
in stock
$61.00 $43.00
Pack Size: 25g
Purity: ≥ 98% (Assay by titration)
in stock
$96.00 $67.00
Pack Size: 100g
Purity: ≥ 98% (Assay by titration)
in stock
$202.00 $142.00
Pack Size: 250g
Purity: ≥ 98% (Assay by titration)
in stock
$338.00 $237.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA0038C5
Chemical Name: Hyodeoxycholic acid
CAS Number: 83-49-8
Molecular Formula: C24H40O4
Molecular Weight: 392.5720
MDL Number: MFCD00003681
SMILES: OC1CC[C@]2(C(C1)CC([C@@H]1[C@@H]2CC[C@]2([C@H]1CC[C@@H]2[C@@H](CCC(=O)O)C)C)O)C
Properties
Complexity: 605  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 10  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 28  
Hydrogen Bond Acceptor Count: 4  
Hydrogen Bond Donor Count: 3  
Isotope Atom Count: 0  
Rotatable Bond Count: 4  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 4.9  
Literature fold

Title: 11β-Hydroxysteroid dehydrogenase-1 is involved in bile acid homeostasis by modulating fatty acid transport protein-5 in the liver of mice.

Journal: Molecular metabolism20140801

Title: Human UDP-glucuronosyltransferases: feedback loops between substrates and ligands of their transcription factors.

Journal: Biochemical pharmacology20121015

Title: BASIC--a bile acid-sensitive ion channel highly expressed in bile ducts.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology20121001

Title: Gender, but not CYP7A1 or SLCO1B1 polymorphism, affects the fasting plasma concentrations of bile acids in human beings.

Journal: Basic & clinical pharmacology & toxicology20120301

Title: A tandem mass spectrometric study of bile acids: interpretation of fragmentation pathways and differentiation of steroid isomers.

Journal: Steroids20120201

Title: Gender-divergent profile of bile acid homeostasis during aging of mice.

Journal: PloS one20120101

Title: Dysfunction of organic anion transporting polypeptide 1a1 alters intestinal bacteria and bile acid metabolism in mice.

Journal: PloS one20120101

Title: Effects of human and porcine bile on the proteome of Helicobacter hepaticus.

Journal: Proteome science20120101

Title: Refined Qingkailing Protects MCAO Mice from Endoplasmic Reticulum Stress-Induced Apoptosis with a Broad Time Window.

Journal: Evidence-based complementary and alternative medicine : eCAM20120101

Title: Chinese medicine injection qingkailing for treatment of acute ischemia stroke: a systematic review of randomized controlled trials.

Journal: Evidence-based complementary and alternative medicine : eCAM20120101

Title: A novel 'target constituent knock-out' strategy coupled with TLC, UPLC-ELSD and microcalorimetry for preliminary screening of antibacterial constituents in Calculus bovis.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20111115

Title: Inhibition of human UGT2B7 gene expression in transgenic mice by the constitutive androstane receptor.

Journal: Molecular pharmacology20110601

Title: Regulated phosphorylation of a major UDP-glucuronosyltransferase isozyme by tyrosine kinases dictates endogenous substrate selection for detoxification.

Journal: The Journal of biological chemistry20110114

Title: Differentiation of various traditional Chinese medicines derived from animal bile and gallstone: simultaneous determination of bile acids by liquid chromatography coupled with triple quadrupole mass spectrometry.

Journal: Journal of chromatography. A20110107

Title: Diurnal variations of mouse plasma and hepatic bile acid concentrations as well as expression of biosynthetic enzymes and transporters.

Journal: PloS one20110101

Title: Profiling circulating and urinary bile acids in patients with biliary obstruction before and after biliary stenting.

Journal: PloS one20110101

Title: Voluntary wheel running exercise and dietary lactose concomitantly reduce proportion of secondary bile acids in rat feces.

Journal: Journal of applied physiology (Bethesda, Md. : 1985)20100901

Title: Chemical genetic screen identifies lithocholic acid as an anti-aging compound that extends yeast chronological life span in a TOR-independent manner, by modulating housekeeping longevity assurance processes.

Journal: Aging20100701

Title: Regulation of bile acid synthesis by fat-soluble vitamins A and D.

Journal: The Journal of biological chemistry20100507

Title: Identification of human UGT2B7 as the major isoform involved in the O-glucuronidation of chloramphenicol.

Journal: Drug metabolism and disposition: the biological fate of chemicals20100301

Title: Liver X receptor agonist methyl-3β-hydroxy-5α,6α-epoxycholanate attenuates atherosclerosis in apolipoprotein E knockout mice without increasing plasma triglyceride.

Journal: Pharmacology20100101

Title: Challenges predicting ligand-receptor interactions of promiscuous proteins: the nuclear receptor PXR.

Journal: PLoS computational biology20091201

Title: Consumption of some polyphenols reduces fecal deoxycholic acid and lithocholic acid, the secondary bile acids of risk factors of colon cancer.

Journal: Journal of agricultural and food chemistry20090923

Title: 3-ketocholanoic acid is the major in vitro human hepatic microsomal metabolite of lithocholic acid.

Journal: Drug metabolism and disposition: the biological fate of chemicals20090901

Title: Serum bile acid profiling reflects enterohepatic detoxification state and intestinal barrier function in inflammatory bowel disease.

Journal: World journal of gastroenterology20090707

Title: Improved analysis of bile acids in tissues and intestinal contents of rats using LC/ESI-MS.

Journal: Journal of lipid research20090101

Title: Bear bile: dilemma of traditional medicinal use and animal protection.

Journal: Journal of ethnobiology and ethnomedicine20090101

Title: The inhibitory effects of cholalic acid and hyodeoxycholalic acid on the expression of TNFalpha and IL-1beta after cerebral ischemia in rats.

Journal: Archives of pharmacal research20090101

Title: Regulation of sulfotransferase and UDP-glucuronosyltransferase gene expression by the PPARs.

Journal: PPAR research20090101

Title: Novel polymorphic human UDP-glucuronosyltransferase 2A3: cloning, functional characterization of enzyme variants, comparative tissue expression, and gene induction.

Journal: Molecular pharmacology20080901

Title: Novel potent and selective bile acid derivatives as TGR5 agonists: biological screening, structure-activity relationships, and molecular modeling studies.

Journal: Journal of medicinal chemistry20080327

Title: Biotransformation of lithocholic acid by rat hepatic microsomes: metabolite analysis by liquid chromatography/mass spectrometry.

Journal: Drug metabolism and disposition: the biological fate of chemicals20080201

Title: Use of selected chemical markers in combination with a multiple regression model to assess the contribution of domesticated animal sources of fecal pollution in the environment.

Journal: Chemosphere20071101

Title: [Determination of chyodeoxycholic acid in Bile Arisaema by HPLC-ELSD].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20070801

Title: Comparative study on major bioactive components in natural, artificial and in-vitro cultured Calculus Bovis.

Journal: Chemical & pharmaceutical bulletin20070101

Title: Simultaneous determination of geniposide, baicalin, cholic acid and hyodeoxycholic acid in rat serum for the pharmacokinetic investigations by high performance liquid chromatography-tandem mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20060914

Title: 3alpha-6alpha-Dihydroxy-7alpha-fluoro-5beta-cholanoate (UPF-680), physicochemical and physiological properties of a new fluorinated bile acid that prevents 17alpha-ethynyl-estradiol-induced cholestasis in rats.

Journal: Toxicology and applied pharmacology20060715

Title: Role for enhanced faecal excretion of bile acid in hydroxysteroid sulfotransferase-mediated protection against lithocholic acid-induced liver toxicity.

Journal: Xenobiotica; the fate of foreign compounds in biological systems20060701

Title: Determination of three bile acids in artificial Calculus Bovis and its medicinal preparations by micellar electrokinetic capillary electrophoresis.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20060606

Title: Mice lacking Mrp3 (Abcc3) have normal bile salt transport, but altered hepatic transport of endogenous glucuronides.

Journal: Journal of hepatology20060401

Title: Simultaneous determination of nine components in Qingkailing injection by HPLC/ELSD/DAD and its application to the quality control.

Journal: Journal of pharmaceutical and biomedical analysis20060303

Title: Enzymatic production of bile Acid glucuronides used as analytical standards for liquid chromatography-mass spectrometry analyses.

Journal: Molecular pharmaceutics20060101

Title: Resistance to ursodeoxycholic acid-induced growth arrest can also result in resistance to deoxycholic acid-induced apoptosis and increased tumorgenicity.

Journal: BMC cancer20060101

Title: Isolation and determination of bile acids.

Journal: European journal of drug metabolism and pharmacokinetics20060101

Title: Simultaneous determination of major bioactive components in Qingkailing injection by high-performance liquid chromatography with evaporative light scattering detection.

Journal: Chemical & pharmaceutical bulletin20051101

Title: [Simultaneous determination of five groups of components in qingkailing injection by high performance liquid chromatography with photo diode array detector and evaporative light scattering detector].

Journal: Se pu = Chinese journal of chromatography20050901

Title: Interfacial properties of most monofluorinated bile acids deviate markedly from the natural congeners: studies with the Langmuir-Pockels surface balance.

Journal: Journal of lipid research20050301

Title: Effect of dried plums on colon cancer risk factors in rats.

Journal: Nutrition and cancer20050101

Title: Identification of UGT2B9*2 and UGT2B33 isolated from female rhesus monkey liver.

Journal: Archives of biochemistry and biophysics20040601

Title: Effects of ileo-rectal anastomosis on cholesterol metabolism in pigs fed either casein or extruded soya beans.

Journal: The British journal of nutrition20040501

Title: [Study on extraction technique of HDCA].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20040501

Title: UDP-glucuronosyltransferase and sulfotransferase polymorphisms, sex hormone concentrations, and tumor receptor status in breast cancer patients.

Journal: Breast cancer research : BCR20040101

Title: Fluorescence resonance energy transfer in a novel cyclodextrin-peptide conjugate for detecting steroid molecules.

Journal: Bioorganic & medicinal chemistry letters20031215

Title: Substrate specificities of rat oatp1 and ntcp: implications for hepatic organic anion uptake.

Journal: American journal of physiology. Gastrointestinal and liver physiology20031101

Title: Steroids in the intestinal tract of rats are affected by dietary-fibre-rich barley-based diets.

Journal: The British journal of nutrition20031101

Title: Peroxisome proliferator-activated receptor alpha induces hepatic expression of the human bile acid glucuronidating UDP-glucuronosyltransferase 2B4 enzyme.

Journal: The Journal of biological chemistry20030829

Title: Glucosidation of hyodeoxycholic acid by UDP-glucuronosyltransferase 2B7.

Journal: Biochemical pharmacology20030201

Title: The cytotoxicity of hydrophobic bile acids is ameliorated by more hydrophilic bile acids in intestinal cell lines IEC-6 and Caco-2.

Journal: Oncology reports20030101

Title: Dietary bile acids inhibit potentially elemental diet-induced small intestinal atrophy in rats.

Journal: International journal of molecular medicine20021101

Title: [Study on effect of qingkailing injection and its active principle in inducing cell apoptosis in human acute promyelocytic leukemia].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine20011101

Title: Hyodeoxycholic acid efficiently suppresses atherosclerosis formation and plasma cholesterol levels in mice.

Journal: Journal of lipid research20010801

Title: Effect of bile salts on colonic mucus secretion in isolated vascularly perfused rat colon.

Journal: Digestive diseases and sciences20010601

Title: Hydrophilic and hydrophobic bile acids exhibit different cytotoxicities through cytolysis, interleukin-8 synthesis and apoptosis in the intestinal epithelial cell lines. IEC-6 and Caco-2 cells.

Journal: Scandinavian journal of gastroenterology20010501

Title: UGT2B23, a novel uridine diphosphate-glucuronosyltransferase enzyme expressed in steroid target tissues that conjugates androgen and estrogen metabolites.

Journal: Endocrinology19991201

Title: Reinduction of the hypnotic effects of thiopental with NSAIDs by decreasing thiopental plasma protein binding in humans.

Journal: Acta anaesthesiologica Scandinavica19930401

Title: Complementary deoxyribonucleic acid cloning and expression of a human liver uridine diphosphate-glucuronosyltransferase glucuronidating carboxylic acid-containing drugs.

Journal: The Journal of pharmacology and experimental therapeutics19930101

Title: Isolation and characterization of hyodeoxycholic-acid: UDP-glucuronosyltransferase from human liver.

Journal: European journal of biochemistry19910901

Title: Sato H, et al. Novel potent and selective bile acid derivatives as TGR5 agonists: biological screening, structure-activity relationships, and molecular modeling studies. J Med Chem. 2008 Mar 27;51(6):1831-41.

Title: Shih DM, et al. Hyodeoxycholic acid improves HDL function and inhibits atherosclerotic lesion formation in LDLR-knockout mice. FASEB J. 2013 Sep;27(9):3805-17.

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