Title: Heterogeneity of cholinergic denervation in Parkinson's disease without dementia.
Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20120801
Title: DJ-1 and αSYN in LRRK2 CSF do not correlate with striatal dopaminergic function.
Journal: Neurobiology of aging 20120401
Title: In vivo evidence for low striatal vesicular monoamine transporter 2 (VMAT2) availability in cocaine abusers.
Journal: The American journal of psychiatry 20120101
Title: A concise synthesis of tetrabenazine: an intramolecular aza-Prins-type cyclization via oxidative C-H activation.
Journal: Organic letters 20111216
Title: Sigma receptor binding of tetrabenazine series tracers targeting VMAT2 in rat pancreas.
Journal: Nuclear medicine and biology 20111001
Title: Altered affinity of the platelet vesicular monoamine transporter 2 to dihydrotetrabenazine in children with major depression.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20110901
Title: Leucoaraiosis, nigrostriatal denervation and motor symptoms in Parkinson's disease.
Journal: Brain : a journal of neurology 20110801
Title: Platelet vesicular monoamine transporter 2 density in the disruptive behavior disorders.
Journal: Journal of child and adolescent psychopharmacology 20110801
Title: Synthesis and biological evaluation of 3-alkyl-dihydrotetrabenazine derivatives as vesicular monoamine transporter-2 (VMAT2) ligands.
Journal: Bioorganic & medicinal chemistry letters 20110601
Title: Assessment of mild dementia with amyloid and dopamine terminal positron emission tomography.
Journal: Brain : a journal of neurology 20110601
Title: Age-specific progression of nigrostriatal dysfunction in Parkinson's disease.
Journal: Annals of neurology 20110501
Title: Preparation and evaluation of tetrabenazine enantiomers and all eight stereoisomers of dihydrotetrabenazine as VMAT2 inhibitors.
Journal: European journal of medicinal chemistry 20110501
Title: Rat pancreas uptake of [11C]dihydrotetrabenazine stereoisomers.
Journal: Nuclear medicine and biology 20101101
Title: The effect of chronic methylphenidate administration on presynaptic dopaminergic parameters in a rat model for ADHD.
Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20101001
Title: 11C-dihydrotetrabenazine beta-cell imaging.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20100901
Title: Assessment of islet specificity of dihydrotetrabenazine radiotracer binding in rat pancreas and human pancreas.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20100901
Title: Influence of a low dose of amphetamine on vesicular monoamine transporter binding: a PET (+)[11C]DTBZ study in humans.
Journal: Synapse (New York, N.Y.) 20100601
Title: Progression of dopaminergic depletion in a model of MPTP-induced Parkinsonism in non-human primates. An (18)F-DOPA and (11)C-DTBZ PET study.
Journal: Neurobiology of disease 20100601
Title: Comparing fludeoxyglucose F18-PET assessment of regional cerebral glucose metabolism and [11C]dihydrotetrabenazine-PET in evaluation of early dementia and mild cognitive impairment.
Journal: Archives of neurology 20100401
Title: The utility of [(11)C] dihydrotetrabenazine positron emission tomography scanning in assessing beta-cell performance after sleeve gastrectomy and duodenal-jejunal bypass.
Journal: Surgery 20100201
Title: Dopamine transporter PET in normal aging: dopamine transporter decline and its possible role in preservation of motor function.
Journal: Synapse (New York, N.Y.) 20100201
Title: In vivo [11C]dihydrotetrabenazine binding in rat striatum: sensitivity to dopamine concentrations.
Journal: Nuclear medicine and biology 20100101
Title: Pyrrolidine analogues of lobelane: relationship of affinity for the dihydrotetrabenazine binding site with function of the vesicular monoamine transporter 2 (VMAT2).
Journal: Journal of medicinal chemistry 20091210
Title: Dimethyltryptamine and other hallucinogenic tryptamines exhibit substrate behavior at the serotonin uptake transporter and the vesicle monoamine transporter.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20091201
Title: Synthesis and evaluation of 2-amino-dihydrotetrabenzine derivatives as probes for imaging vesicular monoamine transporter-2.
Journal: Bioorganic & medicinal chemistry letters 20090901
Title: New MRI, 18F-DOPA and 11C-(+)-alpha-dihydrotetrabenazine templates for Macaca fascicularis neuroimaging: advantages to improve PET quantification.
Journal: NeuroImage 20090815
Title: Visualizing vesicular dopamine dynamics in Parkinson's disease.
Journal: Synapse (New York, N.Y.) 20090801
Title: Signal separation and parameter estimation in noninvasive dual-tracer PET scans using reference-region approaches.
Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20090701
Title: Noninvasive imaging of pancreatic beta cells.
Journal: Nature reviews. Endocrinology 20090701
Title: Measurement of plasmalemmal dopamine transport, vesicular dopamine transport, and K(+)-stimulated dopamine release in frozen rat brain tissue.
Journal: Journal of neuroscience methods 20090615
Title: Asymmetric synthesis of tetrabenazine and dihydrotetrabenazine.
Journal: The Journal of organic chemistry 20090515
Title: Familial parkinsonism: study of original Sagamihara PARK8 (I2020T) kindred with variable clinicopathologic outcomes.
Journal: Parkinsonism & related disorders 20090501
Title: Striatal [11C]dihydrotetrabenazine and [11C]methylphenidate binding in Tourette syndrome.
Journal: Neurology 20090421
Title: PET demonstrates reduced dopamine transporter expression in PD with dyskinesias.
Journal: Neurology 20090407
Title: Dyskinesia in Parkinson disease: back for the future?
Journal: Neurology 20090407
Title: Pancreatic imaging with 11C-dihydrotetrabenazine PET: a perspective.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20090301
Title: 11C-dihydrotetrabenazine PET of the pancreas in subjects with long-standing type 1 diabetes and in healthy controls.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20090301
Title: Impairment of nigrostriatal dopamine neurotransmission by manganese is mediated by pre-synaptic mechanism(s): implications to manganese-induced parkinsonism.
Journal: Journal of neurochemistry 20081201
Title: Dopamine modulating drugs influence striatal (+)-[11C]DTBZ binding in rats: VMAT2 binding is sensitive to changes in vesicular dopamine concentration.
Journal: Synapse (New York, N.Y.) 20081101
Title: Increased vesicular monoamine transporter binding during early abstinence in human methamphetamine users: Is VMAT2 a stable dopamine neuron biomarker?
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20080924
Title: Novel hypoglycemic dihydropyridones serendipitously discovered from O- versus C-alkylation in the synthesis of VMAT2 antagonists.
Journal: Bioorganic & medicinal chemistry letters 20080915
Title: In vivo imaging of beta-cell mass in rats using 18F-FP-(+)-DTBZ: a potential PET ligand for studying diabetes mellitus.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20080701
Title: Striatal dopaminergic terminals in type 1 and type 2 alcoholics measured with [3H]dihydrotetrabenazine and human whole hemisphere autoradiography.
Journal: Psychiatry research 20080530
Title: VMAT2 and dopamine neuron loss in a primate model of Parkinson's disease.
Journal: Journal of neurochemistry 20080401
Title: Whole body [11C]-dihydrotetrabenazine imaging of baboons: biodistribution and human radiation dosimetry estimates.
Journal: European journal of nuclear medicine and molecular imaging 20080401
Title: Dihydrotetrabenazine positron emission tomography imaging in early, untreated Parkinson's disease.
Journal: Annals of neurology 20080301
Title: [Quick and simple synthesis of (11)C-(+)-alpha-dihydrotetrabenazine to be used as a PET radioligand of vesicular monoamine transporters].
Journal: Revista espanola de medicina nuclear 20080101
Title: [Use of 11C-(+)-alpha -dihydrotetrabenazine for the assessment of dopaminergic innervation in animal models of Parkinson's disease].
Journal: Revista espanola de medicina nuclear 20080101
Title: Differentiating Alzheimer's disease from dementia with Lewy bodies and Parkinson's disease with (+)-[11C]dihydrotetrabenazine positron emission tomography.
Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association 20080101
Title: Normal dopaminergic nigrostriatal innervation in SPG3A hereditary spastic paraplegia.
Journal: Journal of neurogenetics 20080101
Title: In vivo measurement of density and affinity of the monoamine vesicular transporter in a unilateral 6-hydroxydopamine rat model of PD.
Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20070701
Title: Reduced platelet vesicular monoamine transporter density in Tourette's syndrome pediatric male patients.
Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20070701
Title: Pharmacokinetics of [(18)F]fluoroalkyl derivatives of dihydrotetrabenazine in rat and monkey brain.
Journal: Nuclear medicine and biology 20070401
Title: Characterization of optically resolved 9-fluoropropyl-dihydrotetrabenazine as a potential PET imaging agent targeting vesicular monoamine transporters.
Journal: Nuclear medicine and biology 20070401
Title: Interaction of amphetamines and related compounds at the vesicular monoamine transporter.
Journal: The Journal of pharmacology and experimental therapeutics 20061001
Title: Visualizing pancreatic beta-cell mass with [11C]DTBZ.
Journal: Nuclear medicine and biology 20061001
Title: Positron emission tomography of monoaminergic vesicular binding in aging and Parkinson disease.
Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20060901
Title: Fluoroalkyl derivatives of dihydrotetrabenazine as positron emission tomography imaging agents targeting vesicular monoamine transporters.
Journal: Nuclear medicine and biology 20060801
Title: Longitudinal noninvasive PET-based beta cell mass estimates in a spontaneous diabetes rat model.
Journal: The Journal of clinical investigation 20060601
Title: Evaluation of the integrity of the dopamine system in a rodent model of Parkinson's disease: small animal positron emission tomography compared to behavioral assessment and autoradiography.
Journal: Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20060101
Title: PET in LRRK2 mutations: comparison to sporadic Parkinson's disease and evidence for presymptomatic compensation.
Journal: Brain : a journal of neurology 20051201
Title: Platelet vesicular monoamine transporter density in untreated patients diagnosed with social phobia.
Journal: Psychiatry research 20050915
Title: The influence of measurement uncertainties on the evaluation of the distribution volume ratio and binding potential in rat studies on a microPET R4: a phantom study.
Journal: Physics in medicine and biology 20050621
Title: 11C-DTBZ and 18F-FDG PET measures in differentiating dementias.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20050601
Title: Decreased platelet vesicular monoamine transporter density in children and adolescents with attention deficit/hyperactivity disorder.
Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20050301
Title: Decreased platelet vesicular monoamine transporter density in habitual smokers.
Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20050301
Title: The role of radiotracer imaging in Parkinson disease.
Journal: Neurology 20050125
Title: Lack of regional selectivity during the progression of Parkinson disease: implications for pathogenesis.
Journal: Archives of neurology 20041201
Title: Identification of tissue-restricted transcripts in human islets.
Journal: Endocrinology 20041001
Title: Differential effects of scopolamine on in vivo binding of dopamine transporter and vesicular monoamine transporter radioligands in rat brain.
Journal: Experimental neurology 20040801
Title: Behavioral and neurochemical consequences of long-term intravenous self-administration of MDMA and its enantiomers by rhesus monkeys.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20040701
Title: Long-term reproducibility of in vivo measures of specific binding of radioligands in rat brain.
Journal: Nuclear medicine and biology 20040701
Title: Striatal monoamine terminals in Lewy body dementia and Alzheimer's disease.
Journal: Annals of neurology 20040601
Title: Electrochemical monitoring of transport by a vesicular monoamine transporter expressed in Xenopus oocytes.
Journal: Journal of neuroscience methods 20040215
Title: Dopamine transmission in DYT1 dystonia.
Journal: Advances in neurology 20040101
Title: [11C]DTBZ-PET correlates of levodopa responses in asymmetric Parkinson's disease.
Journal: Brain : a journal of neurology 20031201
Title: Raclopride studies of dopamine release: dependence on presynaptic integrity.
Journal: Biological psychiatry 20031201
Title: Apparent opposite effects of tetrabenazine and reserpine on the toxic effects of 1-methyl-4-phenylpyridinium or 6-hydroxydopamine on nigro-striatal dopaminergic neurons.
Journal: Brain research 20031107
Title: Assessment of neuroimaging techniques as biomarkers of the progression of Parkinson's disease.
Journal: Experimental neurology 20031101
Title: Escalating dose methamphetamine pretreatment alters the behavioral and neurochemical profiles associated with exposure to a high-dose methamphetamine binge.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20031001
Title: Increased ventral striatal monoaminergic innervation in Tourette syndrome.
Journal: Neurology 20030812
Title: REM sleep behavior disorder is related to striatal monoaminergic deficit in MSA.
Journal: Neurology 20030708
Title: Obstructive sleep apnea is related to a thalamic cholinergic deficit in MSA.
Journal: Neurology 20030708
Title: VMAT2 binding is elevated in dopa-responsive dystonia: visualizing empty vesicles by PET.
Journal: Synapse (New York, N.Y.) 20030701
Title: Decreased limbic vesicular monoamine transporter 2 in a genetic rat model of depression.
Journal: Brain research 20030307
Title: Elevated platelet vesicular monoamine transporter density in untreated patients diagnosed with major depression.
Journal: Psychiatry research 20021115
Title: Methylphenidate redistributes vesicular monoamine transporter-2: role of dopamine receptors.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20021001
Title: Lack of effect of testosterone and dihydrotestosterone compared to 17beta-oestradiol in 1-methyl-4-phenyl-1,2,3,6, tetrahydropyridine-mice.
Journal: Journal of neuroendocrinology 20020901
Title: Increased platelet vesicular monoamine transporter density in adult schizophrenia patients.
Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20020801
Title: Chronic clozapine, but not haloperidol, treatment affects rat brain vesicular monoamine transporter 2.
Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20020601
Title: In vivo measures of dopaminergic radioligands in the rat brain: equilibrium infusion studies.
Journal: Synapse (New York, N.Y.) 20020301
Title: Methylenedioxymethamphetamine decreases plasmalemmal and vesicular dopamine transport: mechanisms and implications for neurotoxicity.
Journal: The Journal of pharmacology and experimental therapeutics 20020301
Title: Phencyclidine increases vesicular dopamine uptake.
Journal: European journal of pharmacology 20020301
Title: Dual-[11C]tracer single-acquisition positron emission tomography studies.
Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20011201
Title: Characterization of high-affinity [3H]TBZOH binding to the human platelet vesicular monoamine transporter.
Journal: Life sciences 20010928
Title: Cocaine-induced increases in vesicular dopamine uptake: role of dopamine receptors.
Journal: The Journal of pharmacology and experimental therapeutics 20010901
Title: Assessing the integrity of the dopamine system in Parkinson's disease: how best to do it?
Journal: Movement disorders : official journal of the Movement Disorder Society 20010901
Title: Decreased densities of dopamine and serotonin transporters and of vesicular monoamine transporter 2 in severely kainic acid lesioned subregions of the striatum.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20010101
Title: Kilbourn M, et al. Binding of alpha-dihydrotetrabenazine to the vesicular monoamine transporter is stereospecific. Eur J Pharmacol. 1995 May 24;278(3):249-52.