Name: Name:Necrostatin 2 S-Enantiomer
Brand: AABLOCKS
SKU: AA00G3ML
Rating: 90 (10 reviews)

Catalog No.: AA00G3ML

852391-20-9 | Necrostatin 2 S-Enantiomer

Pack Size： 1mg

Purity： 99%

1 week

$162.00 $113.00

Pack Size： 5mg

Purity： 99%

1 week

$352.00 $247.00

Pack Size： 10mg

Purity： 99%

1 week

$543.00 $380.00

Pack Size： 50mg

Purity： 99%

1 week

$1,320.00 $924.00

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Technical Information

Catalog Number: AA00G3ML

Chemical Name: Necrostatin 2 S-Enantiomer

CAS Number: 852391-20-9

Molecular Formula: C13H12ClN3O2

Molecular Weight: 277.7063

MDL Number: MFCD26960959

SMILES: CN1C(=O)[C@@H](NC1=O)Cc1c[nH]c2c1cccc2Cl

Properties

Complexity: 403

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 1

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 19

Hydrogen Bond Acceptor Count: 2

Hydrogen Bond Donor Count: 2

Isotope Atom Count: 0

Rotatable Bond Count: 2

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 1.9

Literature fold

Title: Structure-activity relationship study of novel necroptosis inhibitors.

Journal: Bioorganic & medicinal chemistry letters20051115

Title: Teng X, Keys H, Jeevanandam A, Structure-activity relationship study of ,2,3thiadiazole necroptosis inhibitors. Bioorg Med Chem Lett. 2007 Dec 15;17(24):6836-40.

Title: Takahashi N, et al. Necrostatin-1 analogues: critical issues on the specificity, activity and in vivo use in experimental disease models. Cell Death Dis. 2012 Nov 29;3:e437.

Title: Jagtap PG, Degterev A, Choi S, Structure-activity relationship study of tricyclic necroptosis inhibitors. J Med Chem. 2007 Apr 19;50(8):1886-95.

Title: Teng X, Degterev A, Jagtap P, Structure-activity relationship study of novel necroptosis inhibitors. Bioorg Med Chem Lett. 2005 Nov 15;15(22):5039-44.