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862168-11-4,MFCD16876808
Catalog No.:AA01FFMW

862168-11-4 | 4-Chloro-6-(2-methoxyphenyl)-2-pyrimidinamine

Pack Size
Purity
Availability
Price(USD)
Quantity
  
100mg
95%
in stock  
$311.00   $218.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA01FFMW
Chemical Name:
4-Chloro-6-(2-methoxyphenyl)-2-pyrimidinamine
CAS Number:
862168-11-4
Molecular Formula:
C11H10ClN3O
Molecular Weight:
235.6696
MDL Number:
MFCD16876808
SMILES:
COC1=CC=CC=C1C2=CC(=NC(=N2)N)Cl
Properties
Computed Properties
 
Complexity:
229  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
16  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0  
Rotatable Bond Count:
2  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
2.1  

Literature

Title: Optimization of potent, selective, and orally bioavailable pyrrolodinopyrimidine-containing inhibitors of heat shock protein 90. Identification of development candidate 2-amino-4-{4-chloro-2-[2-(4-fluoro-1H-pyrazol-1-yl)ethoxy]-6-methylphenyl}-N-(2,2-difluoropropyl)-5,7-dihydro-6H-pyrrolo[3,4-d]pyrimidine-6-carboxamide.

Journal: Journal of medicinal chemistry 20110512

Title: Fragment-based drug discovery applied to Hsp90. Discovery of two lead series with high ligand efficiency.

Journal: Journal of medicinal chemistry 20100826

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SDS
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Tags:862168-11-4 Molecular Formula|862168-11-4 MDL|862168-11-4 SMILES|862168-11-4 4-Chloro-6-(2-methoxyphenyl)-2-pyrimidinamine
Catalog No.: AA01FFMW
862168-11-4,MFCD16876808
862168-11-4 | 4-Chloro-6-(2-methoxyphenyl)-2-pyrimidinamine
Pack Size： 100mg
Purity： 95%
in stock
$311.00 $218.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA01FFMW
Chemical Name: 4-Chloro-6-(2-methoxyphenyl)-2-pyrimidinamine
CAS Number: 862168-11-4
Molecular Formula: C11H10ClN3O
Molecular Weight: 235.6696
MDL Number: MFCD16876808
SMILES: COC1=CC=CC=C1C2=CC(=NC(=N2)N)Cl
Properties
Complexity: 229  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 16  
Hydrogen Bond Acceptor Count: 4  
Hydrogen Bond Donor Count: 1  
Isotope Atom Count: 0  
Rotatable Bond Count: 2  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 2.1  
Literature fold

Title: Optimization of potent, selective, and orally bioavailable pyrrolodinopyrimidine-containing inhibitors of heat shock protein 90. Identification of development candidate 2-amino-4-{4-chloro-2-[2-(4-fluoro-1H-pyrazol-1-yl)ethoxy]-6-methylphenyl}-N-(2,2-difluoropropyl)-5,7-dihydro-6H-pyrrolo[3,4-d]pyrimidine-6-carboxamide.

Journal: Journal of medicinal chemistry20110512

Title: Fragment-based drug discovery applied to Hsp90. Discovery of two lead series with high ligand efficiency.

Journal: Journal of medicinal chemistry20100826

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