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874450-44-9,MFCD17167027
Catalog No.:AA00GX8Z

874450-44-9 | SEN 12333

Pack Size
Purity
Availability
Price(USD)
Quantity
  
10mg
≥98%
in stock  
$160.00   $112.00
- +
50mg
≥98%
in stock  
$678.00   $474.00
- +
100mg
≥98%
in stock  
$1,193.00   $835.00
- +
250mg
≥98%
in stock  
$2,641.00   $1,849.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00GX8Z
Chemical Name:
SEN 12333
CAS Number:
874450-44-9
Molecular Formula:
C20H25N3O2
Molecular Weight:
339.4314
MDL Number:
MFCD17167027
SMILES:
O=C(Nc1ccc(cc1)c1cccnc1)CCCCN1CCOCC1
Properties
Computed Properties
 
Complexity:
390  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0  
Rotatable Bond Count:
7  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
2  

Literature

Title: Consequences of linker length alteration of the α7 nicotinic acetylcholine receptor (nAChR) agonist, SEN12333.

Journal: Bioorganic & medicinal chemistry letters 20120401

Title: Novel alpha-7 nicotinic acetylcholine receptor agonists containing a urea moiety: identification and characterization of the potent, selective, and orally efficacious agonist 1-[6-(4-fluorophenyl)pyridin-3-yl]-3-(4-piperidin-1-ylbutyl) urea (SEN34625/WYE-103914).

Journal: Journal of medicinal chemistry 20100610

Title: SAR and biological evaluation of SEN12333/WAY-317538: Novel alpha 7 nicotinic acetylcholine receptor agonist.

Journal: Bioorganic & medicinal chemistry 20090715

Title: Procognitive and neuroprotective activity of a novel alpha7 nicotinic acetylcholine receptor agonist for treatment of neurodegenerative and cognitive disorders.

Journal: The Journal of pharmacology and experimental therapeutics 20090501

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SDS
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1388033-03-1

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Tags:874450-44-9 Molecular Formula|874450-44-9 MDL|874450-44-9 SMILES|874450-44-9 SEN 12333
Catalog No.: AA00GX8Z
874450-44-9,MFCD17167027
874450-44-9 | SEN 12333
Pack Size： 10mg
Purity： ≥98%
in stock
$160.00 $112.00
Pack Size： 50mg
Purity： ≥98%
in stock
$678.00 $474.00
Pack Size： 100mg
Purity： ≥98%
in stock
$1,193.00 $835.00
Pack Size： 250mg
Purity： ≥98%
in stock
$2,641.00 $1,849.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA00GX8Z
Chemical Name: SEN 12333
CAS Number: 874450-44-9
Molecular Formula: C20H25N3O2
Molecular Weight: 339.4314
MDL Number: MFCD17167027
SMILES: O=C(Nc1ccc(cc1)c1cccnc1)CCCCN1CCOCC1
Properties
Complexity: 390  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 25  
Hydrogen Bond Acceptor Count: 4  
Hydrogen Bond Donor Count: 1  
Isotope Atom Count: 0  
Rotatable Bond Count: 7  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 2  
Literature fold

Title: Consequences of linker length alteration of the α7 nicotinic acetylcholine receptor (nAChR) agonist, SEN12333.

Journal: Bioorganic & medicinal chemistry letters20120401

Title: Novel alpha-7 nicotinic acetylcholine receptor agonists containing a urea moiety: identification and characterization of the potent, selective, and orally efficacious agonist 1-[6-(4-fluorophenyl)pyridin-3-yl]-3-(4-piperidin-1-ylbutyl) urea (SEN34625/WYE-103914).

Journal: Journal of medicinal chemistry20100610

Title: SAR and biological evaluation of SEN12333/WAY-317538: Novel alpha 7 nicotinic acetylcholine receptor agonist.

Journal: Bioorganic & medicinal chemistry20090715

Title: Procognitive and neuroprotective activity of a novel alpha7 nicotinic acetylcholine receptor agonist for treatment of neurodegenerative and cognitive disorders.

Journal: The Journal of pharmacology and experimental therapeutics20090501

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Historical Records
1388033-03-1
1388033-03-1
1443279-10-4
1443279-10-4
1060226-55-2
1060226-55-2
2180010-72-2
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