Name: Name:LIMK1inhibitorBMS4-BMS4
Brand: AABLOCKS
SKU: AA01EQCC
Rating: 90 (10 reviews)

Catalog No.: AA01EQCC

905298-84-2 | LIMK1inhibitorBMS4-BMS4

Pack Size： 2mg

Purity： 99%

in stock

$264.00 $185.00

Pack Size： 5mg

Purity： 99%

in stock

$401.00 $281.00

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Technical Information

Catalog Number: AA01EQCC

Chemical Name: LIMK1inhibitorBMS4-BMS4

CAS Number: 905298-84-2

Molecular Formula: C23H23N7O2S

Molecular Weight: 461.5394

MDL Number: MFCD24387531

SMILES: CCNC(=O)Nc1ncc(s1)c1cc(nc(n1)c1cnccn1)c1c(C)cc(cc1C)OC

Properties

Complexity: 632

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 33

Hydrogen Bond Acceptor Count: 8

Hydrogen Bond Donor Count: 2

Isotope Atom Count: 0

Rotatable Bond Count: 6

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 2.6

Literature fold

Title: Modulation of cofilin phosphorylation by inhibition of the Lim family kinases.

Journal: Bioorganic & medicinal chemistry letters20120915

Title: Spred1 and TESK1--two new interaction partners of the kinase MARKK/TAO1 that link the microtubule and actin cytoskeleton.

Journal: Molecular biology of the cell20080401

Title: Cofilin phosphorylation and actin reorganization activities of testicular protein kinase 2 and its predominant expression in testicular Sertoli cells.

Journal: The Journal of biological chemistry20010817

Title: Identification and characterization of TESK2, a novel member of the LIMK/TESK family of protein kinases, predominantly expressed in testis.

Journal: Genomics19991001

Title: Regulation of actin dynamics through phosphorylation of cofilin by LIM-kinase.

Journal: Nature19980625

Title: Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization.

Journal: Nature19980625

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