911715-90-7,MFCD28139065
Catalog No.:AA01EOIF

911715-90-7 | Azd8797

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$96.00   $67.00
- +
5mg
≥98%
in stock  
$328.00   $229.00
- +
10mg
≥98%
in stock  
$572.00   $400.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA01EOIF
Chemical Name:
Azd8797
CAS Number:
911715-90-7
Molecular Formula:
C19H25N5OS2
Molecular Weight:
403.5647
MDL Number:
MFCD28139065
SMILES:
OC[C@H](Nc1nc(S[C@H](c2ccccc2)C)nc2c1sc(n2)N)CC(C)C
Properties
Computed Properties
 
Complexity:
452  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
27  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0  
Rotatable Bond Count:
8  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
4.8  

Literature

Title: Cederblad L, et al. AZD8797 is an allosteric non-competitive modulator of the human CX3CR1 receptor. Biochem J. 2016 Mar 1;473(5):641-9.

Title: Ridderstad Wollberg A, et al. Pharmacological inhibition of the chemokine receptor CX3CR1 attenuates disease in a chronic-relapsing rat model for multiple sclerosis. Proc Natl Acad Sci U S A. 2014 Apr 8;111(14):5409-14.

Title: Sofia Karlströ, et al. Substituted 7-amino-5-thio-thiazolo,5-dpyrimidines as potent and selective antagonists of the fractalkine receptor (CX3CR1). J Med Chem. 2013 Apr 25;56(8):3177-90.

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Tags:911715-90-7 Molecular Formula|911715-90-7 MDL|911715-90-7 SMILES|911715-90-7 Azd8797
Catalog No.: AA01EOIF
911715-90-7,MFCD28139065
911715-90-7 | Azd8797
Pack Size: 1mg
Purity: ≥98%
in stock
$96.00 $67.00
Pack Size: 5mg
Purity: ≥98%
in stock
$328.00 $229.00
Pack Size: 10mg
Purity: ≥98%
in stock
$572.00 $400.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA01EOIF
Chemical Name: Azd8797
CAS Number: 911715-90-7
Molecular Formula: C19H25N5OS2
Molecular Weight: 403.5647
MDL Number: MFCD28139065
SMILES: OC[C@H](Nc1nc(S[C@H](c2ccccc2)C)nc2c1sc(n2)N)CC(C)C
Properties
Complexity: 452  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 2  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 27  
Hydrogen Bond Acceptor Count: 8  
Hydrogen Bond Donor Count: 3  
Isotope Atom Count: 0  
Rotatable Bond Count: 8  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 4.8  
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