Name: Name:Brexpiprazole
Brand: AABLOCKS
SKU: AA00GR86
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA00GR86

Chemical Name: Brexpiprazole

CAS Number: 913611-97-9

Molecular Formula: C25H27N3O2S

Molecular Weight: 433.5658

MDL Number: MFCD27987920

SMILES: O=c1ccc2c([nH]1)cc(cc2)OCCCCN1CCN(CC1)c1cccc2c1ccs2

Properties

Complexity: 636

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 31

Hydrogen Bond Acceptor Count: 5

Hydrogen Bond Donor Count: 1

Isotope Atom Count: 0

Rotatable Bond Count: 7

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 4.7

Literature fold

Title: The preclinical profile of brexpiprazole: what is its clinical relevance for the treatment of psychiatric disorders?

Journal: Expert review of neurotherapeutics20151001

Title: Brexpiprazole for schizophrenia and as adjunct for major depressive disorder: a systematic review of the efficacy and safety profile for this newly approved antipsychotic - what is the number needed to treat, number needed to harm and likelihood to be helped or harmed?

Journal: International journal of clinical practice20150901

Title: Brexpiprazole: First Global Approval.

Journal: Drugs20150901

Title: Brexpiprazole I: in vitro and in vivo characterization of a novel serotonin-dopamine activity modulator.

Journal: The Journal of pharmacology and experimental therapeutics20140901

Title: Ishima T, et al. Potentiation of neurite outgrowth by brexpiprazole, a novel serotonin-dopamine activity modulator: a role for serotonin 5-HT1A and 5-HT2A receptors. Eur Neuropsychopharmacol. 2015 Apr;25(4):505-11.

Title: Yoshimi N, et al. Improvement of dizocilpine-induced social recognition deficits in mice by brexpiprazole, a novel serotonin-dopamine activity modulator. Eur Neuropsychopharmacol. 2015 Mar;25(3):356-64.

913611-97-9 | Brexpiprazole