Name: Name:3-methyl-N-(3-{[3-(trifluoromethyl)phenyl]carbamoyl}phenyl)-1,2-oxazole-5-carboxamide
Brand: AABLOCKS
SKU: AA01EAZ0
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA01EAZ0

Chemical Name: 3-methyl-N-(3-{[3-(trifluoromethyl)phenyl]carbamoyl}phenyl)-1,2-oxazole-5-carboxamide

CAS Number: 924473-59-6

Molecular Formula: C19H14F3N3O3

Molecular Weight: 389.3280

MDL Number: MFCD08495674

SMILES: Cc1noc(c1)C(=O)Nc1cccc(c1)C(=O)Nc1cccc(c1)C(F)(F)F

Properties

Complexity: 572

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 28

Hydrogen Bond Acceptor Count: 7

Hydrogen Bond Donor Count: 2

Isotope Atom Count: 0

Rotatable Bond Count: 4

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 3.7

Literature fold

Title: Computer-based identification of a novel LIMK1/2 inhibitor that synergizes with salirasib to destabilize the actin cytoskeleton.

Journal: Oncotarget20120601

Title: Rak R, et al. Novel LIMK2 Inhibitor Blocks Panc-1 Tumor Growth in a mouse xenograft model. Oncoscience. 2014 Jan 1;1(1):39-48. eCollection 2014.

Title: Mashiach-Farkash E, et al. Computer-based identification of a novel LIMK1/2 inhibitor that synergizes with salirasib to destabilize the actin cytoskeleton. Oncotarget. 2012 Jun;3(6):629-39.

924473-59-6 | 3-methyl-N-(3-{[3-(trifluoromethyl)phenyl]carbamoyl}phenyl)-1,2-oxazole-5-carboxamide