Name: Name:S107
Brand: AABLOCKS
SKU: AA00GW6D
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA00GW6D

Chemical Name: S107

CAS Number: 927871-76-9

Molecular Formula: C11H15NOS

Molecular Weight: 209.3079

MDL Number: MFCD12546447

SMILES: COc1ccc2c(c1)CN(C)CCS2

Properties

Complexity: 188

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 14

Hydrogen Bond Acceptor Count: 3

Hydrogen Bond Donor Count: 0

Isotope Atom Count: 0

Rotatable Bond Count: 1

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 2

Literature fold

Title: Calcium leak through ryanodine receptors leads to atrial fibrillation in 3 mouse models of catecholaminergic polymorphic ventricular tachycardia.

Journal: Circulation research20120831

Title: Ryanodine receptor oxidation causes intracellular calcium leak and muscle weakness in aging.

Journal: Cell metabolism20110803

Title: Two candidates at the heart of dysfunction: The ryanodine receptor and calcium/calmodulin protein kinase II as potential targets for therapeutic intervention-An in vivo perspective.

Journal: Pharmacology & therapeutics20110801

Title: Investigation of the in vitro metabolism of the emerging drug candidate S107 for doping-preventive purposes.

Journal: Journal of mass spectrometry : JMS20110201

Title: Electron ionization mass spectrometry of the ryanodine receptor-based Ca(2+)-channel stabilizer S-107 and its implementation into routine doping control.

Journal: Rapid communications in mass spectrometry : RCM20090801

Title: Doping control analysis of emerging drugs in human plasma - identification of GW501516, S-107, JTV-519, and S-40503.

Journal: Rapid communications in mass spectrometry : RCM20090401

Title: Screening for the calstabin-ryanodine receptor complex stabilizers JTV-519 and S-107 in doping control analysis.

Journal: Drug testing and analysis20090101

927871-76-9 | S107