Title: A Prostacyclin Analog, Cicaprost, Exhibits Potent Anti-Inflammatory Activity in Human Primary Immune Cells and a Uveitis Model.
Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics20170401
Title: Prostacyclin receptor-dependent inhibition of human erythroleukemia cell differentiation is STAT3-dependent.
Journal: Prostaglandins, leukotrienes, and essential fatty acids20120301
Title: Prostaglandin I2 signaling drives Th17 differentiation and exacerbates experimental autoimmune encephalomyelitis.
Journal: PloS one20120101
Title: PGI2 as a regulator of CD4+ subset differentiation and function.
Journal: Prostaglandins & other lipid mediators20111101
Title: Glial cells isolated from dorsal root ganglia express prostaglandin E(2) (EP(4)) and prostacyclin (IP) receptors.
Journal: European journal of pharmacology20110701
Title: Smooth muscle proliferation and role of the prostacyclin (IP) receptor in idiopathic pulmonary arterial hypertension.
Journal: American journal of respiratory and critical care medicine20101101
Title: Activation of prostanoid EP receptors by prostacyclin analogues in rabbit iliac artery: implications for anti-restenotic potential.
Journal: European journal of pharmacology20100901
Title: Cell-type- and cell-cycle-specific anti-mitogenesis by cicaprost.
Journal: Prostaglandins & other lipid mediators20100901
Title: Dominant negative actions of human prostacyclin receptor variant through dimerization: implications for cardiovascular disease.
Journal: Arteriosclerosis, thrombosis, and vascular biology20100901
Title: Prostacyclin receptor suppresses cardiac fibrosis: role of CREB phosphorylation.
Journal: Journal of molecular and cellular cardiology20100801
Title: Cyclooxygenase-2-dependent prostacyclin formation and blood pressure homeostasis: targeted exchange of cyclooxygenase isoforms in mice.
Journal: Circulation research20100205
Title: Recycling of the human prostacyclin receptor is regulated through a direct interaction with Rab11a GTPase.
Journal: Cellular signalling20081201
Title: Prostacyclin receptor-induced STAT3 phosphorylation in human erythroleukemia cells is mediated via Galpha(s) and Galpha(16) hybrid signaling.
Journal: Cellular signalling20081101
Title: Agonist-dependent internalization and trafficking of the human prostacyclin receptor: a direct role for Rab5a GTPase.
Journal: Biochimica et biophysica acta20081001
Title: Differential regulation of RhoA-mediated signaling by the TPalpha and TPbeta isoforms of the human thromboxane A2 receptor: independent modulation of TPalpha signaling by prostacyclin and nitric oxide.
Journal: Cellular signalling20080801
Title: Prostaglandin I2 analogs inhibit Th1 and Th2 effector cytokine production by CD4 T cells.
Journal: Journal of leukocyte biology20070301
Title: Development of a common fully stereocontrolled access to the medicinally important and promising prostacyclin analogues iloprost, 3-oxa-iloprost and cicaprost.
Journal: Chemistry (Weinheim an der Bergstrasse, Germany)20060717
Title: Lack of interaction between prostaglandin E2 receptor subtypes in regulating adenylyl cyclase activity in cultured rat dorsal root ganglion cells.
Journal: European journal of pharmacology20060327
Title: Prostacyclin receptor induces STAT1 and STAT3 phosphorylations in human erythroleukemia cells: a mechanism requiring PTX-insensitive G proteins, ERK and JNK.
Journal: Cellular signalling20060301
Title: Evidence that inward rectifier K+ channels mediate relaxation by the PGI2 receptor agonist cicaprost via a cyclic AMP-independent mechanism.
Journal: Cardiovascular research20060101
Title: Augmented cardiac hypertrophy in response to pressure overload in mice lacking the prostaglandin I2 receptor.
Journal: Circulation20050705
Title: The effect of the farnesyl protein transferase inhibitor SCH66336 on isoprenylation and signalling by the prostacyclin receptor.
Journal: The Biochemical journal20050215
Title: Regulation of thrombomodulin expression in human vascular smooth muscle cells by COX-2-derived prostaglandins.
Journal: Circulation research20050107
Title: Dimerization of the human receptors for prostacyclin and thromboxane facilitates thromboxane receptor-mediated cAMP generation.
Journal: The Journal of biological chemistry20041217
Title: Reduced IP receptors in STZ-induced diabetic rat kidneys and high-glucose-treated mesangial cells.
Journal: American journal of physiology. Renal physiology20041001
Title: Activation of IP prostanoid receptors prevents cardiomyocyte hypertrophy via cAMP-dependent signaling.
Journal: American journal of physiology. Heart and circulatory physiology20040901
Title: Mechanism of cicaprost-induced desensitization in rat pulmonary artery smooth muscle cells involves a PKA-mediated inhibition of adenylyl cyclase.
Journal: American journal of physiology. Lung cellular and molecular physiology20040801
Title: Antimitogenesis linked to regulation of Skp2 gene expression.
Journal: The Journal of biological chemistry20040709
Title: Agonists can discriminate between cloned human and mouse prostacyclin receptors.
Journal: Prostaglandins, leukotrienes, and essential fatty acids20040501
Title: Characterization of the PGI2/IP system in cultured rat mesangial cells.
Journal: Prostaglandins, leukotrienes, and essential fatty acids20040501
Title: Excitatory action of prostanoids on the ferret isolated vagus nerve preparation.
Journal: European journal of pharmacology20040426
Title: Prostacyclin receptor-mediated activation of extracellular signal-regulated kinases 1 and 2.
Journal: Cellular signalling20040401
Title: Induction of hyaluronic acid synthase 2 (HAS2) in human vascular smooth muscle cells by vasodilatory prostaglandins.
Journal: Circulation research20040319
Title: Comparative analysis of the in vivo angiogenic properties of stable prostacyclin analogs: a possible role for peroxisome proliferator-activated receptors.
Journal: Journal of molecular and cellular cardiology20040301
Title: Asymmetric synthesis of the highly potent anti-metastatic prostacyclin analogue cicaprost and its isomer isocicaprost.
Journal: Journal of the American Chemical Society20030813
Title: Prostacylin receptor activation inhibits proliferation of aortic smooth muscle cells by regulating cAMP response element-binding protein- and pocket protein-dependent cyclin a gene expression.
Journal: Molecular pharmacology20030801
Title: Protein kinase A-dependent coupling of mouse prostacyclin receptors to Gi is cell-type dependent.
Journal: European journal of pharmacology20030801
Title: Long-term-desensitization of prostacyclin receptors is independent of the C-terminal tail.
Journal: Biochemical pharmacology20030615
Title: Prostanoid-induced modulation of neuropeptide Y and noradrenaline release from the rat mesenteric bed.
Journal: Autonomic & autacoid pharmacology20030401
Title: Facilitation by endogenous prostaglandins of capsaicin-induced gastric protection in rodents through EP2 and IP receptors.
Journal: The Journal of pharmacology and experimental therapeutics20030301
Title: Cyclooxygenase-2 acts as an endogenous brake on endothelin-1 release by human pulmonary artery smooth muscle cells: implications for pulmonary hypertension.
Journal: Molecular pharmacology20021101
Title: Investigation of the mechanisms of G protein: effector coupling by the human and mouse prostacyclin receptors. Identification of critical species-dependent differences.
Journal: The Journal of biological chemistry20020726
Title: In vitro pharmacological characterization of the prostanoid receptor population in the non-pregnant porcine myometrium.
Journal: European journal of pharmacology20020503
Title: Investigation of a functional requirement for isoprenylation by the human prostacyclin receptor.
Journal: European journal of biochemistry20020301
Title: Differential effects of stable prostacyclin analogs on smooth muscle proliferation and cyclic AMP generation in human pulmonary artery.
Journal: American journal of respiratory cell and molecular biology20020201
Title: Central nociceptive role of prostacyclin (IP) receptor induced by peripheral inflammation.
Journal: Neuroreport20020121
Title: Prostacyclin receptor-independent inhibition of phospholipase C activity by non-prostanoid prostacyclin mimetics.
Journal: British journal of pharmacology20011201
Title: Factors affecting prostacyclin receptor agonist efficacy in different cell types.
Journal: Cellular signalling20011101
Title: Protein kinase A-mediated phosphorylation of serine 357 of the mouse prostacyclin receptor regulates its coupling to G(s)-, to G(i)-, and to G(q)-coupled effector signaling.
Journal: The Journal of biological chemistry20010907
Title: Distinction between relaxations induced via prostanoid EP(4) and IP(1) receptors in pig and rabbit blood vessels.
Journal: British journal of pharmacology20010901
Title: A functional study on prostanoid receptors involved in cultured human iridal melanocyte stimulation.
Journal: Experimental eye research20010701
Title: Regulation of prostacyclin and prostaglandin E(2) receptor mediated responses in adult rat dorsal root ganglion cells, in vitro.
Journal: British journal of pharmacology20010501
Title: Differential effects of 15-deoxy-delta(12,14)-prostaglandin J2 and a peroxisome proliferator-activated receptor gamma agonist on macrophage activation.
Journal: Journal of leukocyte biology20010401
Title: Role of endogenous prostacyclin in gastric ulcerogenic and healing responses--a study using IP-receptor knockout mice.
Journal: Journal of physiology, Paris20010101
Title: The utilization of recombinant prostanoid receptors to determine the affinities and selectivities of prostaglandins and related analogs.
Journal: Biochimica et biophysica acta20000117
Title: The effect of indomethacin and prostacyclin agonists on blood pressure in a rat model of preeclampsia.
Journal: American journal of obstetrics and gynecology19990501
Title: Characterization of the prostanoid receptor(s) on human blood monocytes at which prostaglandin E2 inhibits lipopolysaccharide-induced tumour necrosis factor-alpha generation.
Journal: British journal of pharmacology19970901
Title: Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells.
Journal: British journal of pharmacology19970901
Title: Relaxant actions of nonprostanoid prostacyclin mimetics on human pulmonary artery.
Journal: Journal of cardiovascular pharmacology19970401
