943344-58-9,MFCD22419854
Catalog No.:AA01ENXW

943344-58-9 | Genz-123346

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Technical Information
Catalog Number:
AA01ENXW
Chemical Name:
Genz-123346
CAS Number:
943344-58-9
Molecular Formula:
C52H82N4O14
Molecular Weight:
987.2259
MDL Number:
MFCD22419854
SMILES:
OC(=O)[C@@H]([C@H](C(=O)O)O)O.CCCCCCCCC(=O)N[C@@H]([C@@H](c1ccc2c(c1)OCCO2)O)CN1CCCC1.CCCCCCCCC(=O)N[C@@H]([C@@H](c1ccc2c(c1)OCCO2)O)CN1CCCC1
Properties

Literature

Title: Zhao H, et al. Inhibiting glycosphingolipid synthesis improves glycemic control and insulin sensitivity in animal models of type 2 diabetes. Diabetes. 2007 May;56(5):1210-8.

Title: Chai L, et al. The chemosensitizing activity of inhibitors of glucosylceramide synthase is mediated primarily through modulation of P-gp function. Int J Oncol. 2011 Mar;38(3):701-11.

Title: Shen W, et al. Inhibition of glucosylceramide synthase stimulates autophagy flux in neurons. J Neurochem. 2014 Jun;129(5):884-94

Title: Natoli TA, et al. Inhibition of glucosylceramide accumulation results in effective blockade of polycystic kidney disease in mouse models. Nat Med. 2010 Jul;16(7):788-92.

Title: Morace I, et al. Renal globotriaosylceramide facilitates tubular albumin absorption and its inhibitionprotects against acute kidney injury. Kidney Int. 2019 Aug;96(2):327-341.

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Tags:943344-58-9 Molecular Formula|943344-58-9 MDL|943344-58-9 SMILES|943344-58-9 Genz-123346
Catalog No.: AA01ENXW
943344-58-9,MFCD22419854
943344-58-9 | Genz-123346
This product is typically in stock,please click "Inquire" below or contact us at [email protected]for pricing and availability information.
Inquire
Technical Information
Catalog Number: AA01ENXW
Chemical Name: Genz-123346
CAS Number: 943344-58-9
Molecular Formula: C52H82N4O14
Molecular Weight: 987.2259
MDL Number: MFCD22419854
SMILES: OC(=O)[C@@H]([C@H](C(=O)O)O)O.CCCCCCCCC(=O)N[C@@H]([C@@H](c1ccc2c(c1)OCCO2)O)CN1CCCC1.CCCCCCCCC(=O)N[C@@H]([C@@H](c1ccc2c(c1)OCCO2)O)CN1CCCC1
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