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945526-43-2,MFCD12031591
Catalog No.:AA00H5XJ

945526-43-2 | Stem-Cell Factor/c-Kit Inhibitor, ISCK03

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥95%
in stock  
$49.00   $34.00
- +
5mg
≥95%
in stock  
$156.00   $109.00
- +
10mg
≥95%
in stock  
$238.00   $166.00
- +
25mg
≥95%
in stock  
$530.00   $371.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00H5XJ
Chemical Name:
Stem-Cell Factor/c-Kit Inhibitor, ISCK03
CAS Number:
945526-43-2
Molecular Formula:
C19H21N3O2S
Molecular Weight:
355.4539
MDL Number:
MFCD12031591
SMILES:
O=S(=O)(c1ccc(cc1)C(C)(C)C)Nc1ccc(cc1)n1cncc1
Properties
Properties
 
Form:
Solid  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
522  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0  
Rotatable Bond Count:
5  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
3.9  

Literature

Title: Comparison of the effects of carbon ion and photon irradiation on the angiogenic response in human lung adenocarcinoma cells.

Journal: International journal of radiation oncology, biology, physics 20110801

Title: [4-t-butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) inhibits SCF/c-kit signaling in 501mel human melanoma cells and abolishes melanin production in mice and brownish guinea pigs.

Journal: Biochemical pharmacology 20070901

Title: Na YJ, et al. -t-butylphenyl-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) inhibits SCF/c-kit signaling in 501mel human melanoma cells and abolishes melanin production in mice and brownish guinea pigs. Biochem Pharmacol. 2007 Sep 1;74(5):780-6.

Title: Hirano T, et al. Long noncoding RNA, CCDC26, controls myeloid leukemia cell growth through regulation of KIT expression. Mol Cancer. 2015 Apr 19;14:90. doi: 10.1186/s12943-015-0364-7.

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SDS
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Tags:945526-43-2 Molecular Formula|945526-43-2 MDL|945526-43-2 SMILES|945526-43-2 Stem-Cell Factor/c-Kit Inhibitor, ISCK03
Catalog No.: AA00H5XJ
945526-43-2,MFCD12031591
945526-43-2 | Stem-Cell Factor/c-Kit Inhibitor, ISCK03
Pack Size： 1mg
Purity： ≥95%
in stock
$49.00 $34.00
Pack Size： 5mg
Purity： ≥95%
in stock
$156.00 $109.00
Pack Size： 10mg
Purity： ≥95%
in stock
$238.00 $166.00
Pack Size： 25mg
Purity： ≥95%
in stock
$530.00 $371.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA00H5XJ
Chemical Name: Stem-Cell Factor/c-Kit Inhibitor, ISCK03
CAS Number: 945526-43-2
Molecular Formula: C19H21N3O2S
Molecular Weight: 355.4539
MDL Number: MFCD12031591
SMILES: O=S(=O)(c1ccc(cc1)C(C)(C)C)Nc1ccc(cc1)n1cncc1
Properties
Form: Solid  
Storage: Keep in dry area;2-8℃;  
Complexity: 522  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 25  
Hydrogen Bond Acceptor Count: 4  
Hydrogen Bond Donor Count: 1  
Isotope Atom Count: 0  
Rotatable Bond Count: 5  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 3.9  
Literature fold

Title: Comparison of the effects of carbon ion and photon irradiation on the angiogenic response in human lung adenocarcinoma cells.

Journal: International journal of radiation oncology, biology, physics20110801

Title: [4-t-butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) inhibits SCF/c-kit signaling in 501mel human melanoma cells and abolishes melanin production in mice and brownish guinea pigs.

Journal: Biochemical pharmacology20070901

Title: Na YJ, et al. -t-butylphenyl-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) inhibits SCF/c-kit signaling in 501mel human melanoma cells and abolishes melanin production in mice and brownish guinea pigs. Biochem Pharmacol. 2007 Sep 1;74(5):780-6.

Title: Hirano T, et al. Long noncoding RNA, CCDC26, controls myeloid leukemia cell growth through regulation of KIT expression. Mol Cancer. 2015 Apr 19;14:90. doi: 10.1186/s12943-015-0364-7.

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