Title: Chlorine atom substitution influences radical scavenging activity of 6-chromanol.
Journal: Bioorganic & medicinal chemistry20120701
Title: How lipid unsaturation, peroxyl radical partitioning, and chromanol lipophilic tail affect the antioxidant activity of α-tocopherol: direct visualization via high-throughput fluorescence studies conducted with fluorogenic α-tocopherol analogues.
Journal: Journal of the American Chemical Society20120620
Title: Is the chromanol head group of vitamin E nature's final truth on chain-breaking antioxidants?
Journal: FEBS letters20120323
Title: Potassium 2,2,5,7,8-pentamethylchroman-6-oxide: a rationally designed base for Pd-catalysed amination.
Journal: Chemistry (Weinheim an der Bergstrasse, Germany)20120116
Title: Toxicogenomics and metabolomics of pentamethylchromanol (PMCol)-induced hepatotoxicity.
Journal: Toxicological sciences : an official journal of the Society of Toxicology20111201
Title: 6-Hy-droxy-2,5,7,8-tetra-methyl-3,4-dihydro-2H-1-benzopyran-2-carbonitrile, from synchrotron data.
Journal: Acta crystallographica. Section E, Structure reports online20110801
Title: Toxic metabolite formation from Troglitazone (TGZ): new insights from a DFT study.
Journal: Chemical research in toxicology20110718
Title: On the way to understand antioxidants: chromanol and dimethoxyphenols gas-phase acidities.
Journal: Journal of mass spectrometry : JMS20110701
Title: 2,2,5,7,8-Penta-methyl-chroman-6-yl 2,3,4,6-tetra-O-acetyl-α-d-glucopyran-oside from synchrotron data.
Journal: Acta crystallographica. Section E, Structure reports online20110301
Title: Hypothyroidism of gene-targeted mice lacking Kcnq1.
Journal: Pflugers Archiv : European journal of physiology20110101
Title: Chromanol derivatives--a novel class of CETP inhibitors.
Journal: Bioorganic & medicinal chemistry letters20110101
Title: Blocking effect of NIP-142 on the KCNQ1/KCNE1 channel current expressed in HEK293 cells.
Journal: Biological & pharmaceutical bulletin20110101
Title: Lipid antioxidants: free radical scavenging versus regulation of enzymatic lipid peroxidation.
Journal: Journal of clinical biochemistry and nutrition20110101
Title: Chromanols from Sargassum siliquastrum and their antioxidant activity in HT 1080 cells.
Journal: Chemical & pharmaceutical bulletin20110101
Title: Analysis of lipid content and quality in Arabidopsis plastids.
Journal: Methods in molecular biology (Clifton, N.J.)20110101
Title: Cytoprotective effects of vitamin E homologues against glutamate-induced cell death in immature primary cortical neuron cultures: Tocopherols and tocotrienols exert similar effects by antioxidant function.
Journal: Free radical biology & medicine20101130
Title: Inhibition of vascular smooth muscle cell proliferation by the vitamin E derivative pentamethylhydroxychromane in an in vitro and in vivo study: pivotal role of hydroxyl radical-mediated PLCgamma1 and JAK2 phosphorylation.
Journal: Free radical biology & medicine20100901
Title: Inhibitory effect of PMC, a potent hydrophilic α-tocopherol derivative, on vascular smooth muscle cell proliferation: the pivotal role of PKC-α translocation.
Journal: Pharmaceutical biology20100801
Title: Assessment of oral toxicity and safety of pentamethylchromanol (PMCol), a potential chemopreventative agent, in rats and dogs.
Journal: Toxicology20100629
Title: Synthesis and characterization of BODIPY-alpha-tocopherol: a fluorescent form of vitamin E.
Journal: The Journal of organic chemistry20100507
Title: Asymmetric synthesis of alpha-tocopherol.
Journal: Chemistry (Weinheim an der Bergstrasse, Germany)20100125
Title: In-vitro and in-vivo metabolic studies of the candidate chemopreventative pentamethylchromanol using liquid chromatography/tandem mass spectrometry.
Journal: The Journal of pharmacy and pharmacology20091001
Title: Organocatalytic asymmetric Friedel-Crafts alkylation/cyclization cascade reaction of 1-naphthols and alpha,beta-unsaturated aldehydes: an enantioselective synthesis of chromanes and dihydrobenzopyranes.
Journal: The Journal of organic chemistry20090904
Title: Impact of glucose concentration on cardiac ventricular repolarization under I Kr/I Ks blocking agents.
Journal: Journal of molecular and cellular cardiology20090801
Title: Glycosidic moiety changes the spectroscopic properties of dl-alpha-tocopherol in DMSO/water solution and in organic solvents.
Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy20090715
Title: Diversity-oriented synthesis of furo[3,2-f]chromanes with antimycobacterial activity.
Journal: European journal of medicinal chemistry20090601
Title: In vitro assessment of P450 induction potential of novel chemopreventive agents SR13668, 9-cis-UAB30, and pentamethychromanol in primary cultures of human hepatocytes.
Journal: Chemico-biological interactions20090515
Title: Phenol-based lipophilic fluorescent antioxidant indicators: a rational approach.
Journal: The Journal of organic chemistry20090515
Title: Cholesterol-mediated activation of P-glycoprotein: distinct effects on basal and drug-induced ATPase activities.
Journal: Journal of pharmaceutical sciences20090501
Title: Chain-breaking antioxidant activity of reduced forms of mitochondria-targeted quinones, a novel type of geroprotectors.
Journal: Aging20090501
Title: Comparison of the inhibitory effects of vitamin E analogues on melanogenesis in mouse B16 melanoma cells.
Journal: Cytotechnology20090401
Title: Effects of nitric oxide donor antioxidants containing the phenol vitamin E substructure and a furoxan moiety on ischemia/reperfusion injury.
Journal: Arzneimittel-Forschung20090101
Title: [Highly effective test-system for determination of the total antioxidant activity of human blood serum].
Journal: Biomeditsinskaia khimiia20090101
Title: The specificity of neuroprotection by antioxidants.
Journal: Journal of biomedical science20090101
Title: Diastereoselective synthesis of alpha-tocopherol: a new concept for the formation of chromanols.
Journal: Organic letters20081120
Title: Tocochromanols, plastoquinol, and other biological prenyllipids as singlet oxygen quenchers-determination of singlet oxygen quenching rate constants and oxidation products.
Journal: Free radical biology & medicine20080915
Title: Selective block of IKs plays a significant role in MAP triangulation induced by IKr block in isolated rabbit heart.
Journal: Journal of pharmacological and toxicological methods20080101
Title: A theoretical investigation on the geometry and vibrational spectra of 10,10,2,6,5-pentamethyl-1-hydroxychroman: a model of alpha-tocopherol.
Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy20071231
Title: The effect of the lipophilic cation lucigenin on mitochondria depends on the site of its reduction.
Journal: Biochemical pharmacology20070815
Title: Calculation of the relative acidities and oxidation potentials of para-substituted phenols. A model for alpha-tocopherol in solution.
Journal: Organic & biomolecular chemistry20070607
Title: Chromanol 293B binding in KCNQ1 (Kv7.1) channels involves electrostatic interactions with a potassium ion in the selectivity filter.
Journal: Molecular pharmacology20070601
Title: Generation of superoxide and singlet oxygen from alpha-tocopherolquinone and analogues.
Journal: Free radical research20070601
Title: Identification and quantitation of novel vitamin E metabolites, sulfated long-chain carboxychromanols, in human A549 cells and in rats.
Journal: Journal of lipid research20070501
Title: Modulation of ERG channels by XE991.
Journal: Basic & clinical pharmacology & toxicology20070501
Title: Advantages and limitation of BODIPY as a probe for the evaluation of lipid peroxidation and its inhibition by antioxidants in plasma.
Journal: Bioorganic & medicinal chemistry letters20070401
Title: Neuroprotective effects of PMC, a potent alpha-tocopherol derivative, in brain ischemia-reperfusion: reduced neutrophil activation and anti-oxidant actions.
Journal: Biochemical pharmacology20070301
Title: Kinetic and thermochemical study of the antioxidant activity of sulfur-containing analogues of vitamin E.
Journal: Chemistry (Weinheim an der Bergstrasse, Germany)20070101
Title: Role of kinases and G-proteins in the hyposmotic stimulation of cardiac IKs.
Journal: Biochimica et biophysica acta20061001
Title: A pharmacological action of vitamin E unrelated to its antioxidant capacity.
Journal: Methods and findings in experimental and clinical pharmacology20061001
Title: Rb+ efflux through functional activation of cardiac KCNQ1/minK channels by the benzodiazepine R-L3 (L-364,373).
Journal: Assay and drug development technologies20060801
Title: Incorporated sarcolemmal fish oil fatty acids shorten pig ventricular action potentials.
Journal: Cardiovascular research20060601
Title: NO-donor phenols: a new class of products endowed with antioxidant and vasodilator properties.
Journal: Journal of medicinal chemistry20060518
Title: Formation of singlet oxygen from solutions of vitamin E.
Journal: Free radical research20060301
Title: A biomimetic chromanol cyclization leading to alpha-tocopherol.
Journal: Angewandte Chemie (International ed. in English)20060206
Title: Transformation of alpha-tocopherol (vitamin E) and related chromanol model compounds into their phenoxonium ions by chemical oxidation with the nitrosonium cation.
Journal: The Journal of organic chemistry20051209
Title: The protection of bioenergetic functions in mitochondria by new synthetic chromanols.
Journal: Biochemical pharmacology20051101
Title: Prooxidant and antioxidant activity of vitamin E analogues and troglitazone.
Journal: Chemical research in toxicology20051001
Title: Antioxidant properties of natural and synthetic chromanol derivatives: study by fast kinetics and electron spin resonance spectroscopy.
Journal: The Journal of organic chemistry20050429
Title: Electron-transfer mechanism in radical-scavenging reactions by a vitamin E model in a protic medium.
Journal: Organic & biomolecular chemistry20050221
Title: Role of nitric oxide in Ca2+ sensitivity of the slowly activating delayed rectifier K+ current in cardiac myocytes.
Journal: Circulation research20050107
Title: Both beta-adrenergic receptor stimulation and cardiac tissue type have important roles in elucidating the functional effects of I(Ks) channel blockers in vitro.
Journal: Journal of pharmacological and toxicological methods20050101
Title: Development of a new class of potential antiatherosclerosis agents: NO-donor antioxidants.
Journal: Bioorganic & medicinal chemistry letters20041220
Title: 13C CP/MAS NMR studies of vitamin E model compounds.
Journal: Magnetic resonance in chemistry : MRC20041001
Title: Kinetic studies on stilbazulenyl-bis-nitrone (STAZN), a nonphenolic chain-breaking antioxidant in solution, micelles, and lipid membranes.
Journal: The Journal of organic chemistry20040430
Title: Inhibitory mechanisms of YC-1 and PMC in the induction of iNOS expression by lipoteichoic acid in RAW 264.7 macrophages.
Journal: Biochemical pharmacology20040401
Title: Alpha-tocopherol influences the lipid membrane affinity of desipramine in a pH-dependent manner.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences20040201
Title: Soft ionization mass spectrometry of chromanols produces radical cation molecular ions.
Journal: European journal of mass spectrometry (Chichester, England)20040101
Title: Kinetic study of the electron-transfer oxidation of the phenolate anion of a vitamin E model by molecular oxygen generating superoxide anion in an aprotic medium.
Journal: Organic & biomolecular chemistry20031121
Title: Blockers of the slowly delayed rectifier potassium IKs channel: potential antiarrhythmic agents.
Journal: Current medicinal chemistry. Cardiovascular and hematological agents20031001
Title: Androgen antagonist activity by the antioxidant moiety of vitamin E, 2,2,5,7,8-pentamethyl-6-chromanol in human prostate carcinoma cells.
Journal: Molecular cancer therapeutics20030801
Title: Antioxidant effects of phytosterol and its components.
Journal: Journal of nutritional science and vitaminology20030801
Title: Transmural heterogeneity of the action potential configuration in the feline left ventricle.
Journal: Circulation journal : official journal of the Japanese Circulation Society20030501
Title: Diesel exhaust particle-induced cell death of cultured normal human bronchial epithelial cells.
Journal: Biological & pharmaceutical bulletin20030401
Title: Direct evidence for recycling of myeloperoxidase-catalyzed phenoxyl radicals of a vitamin E homologue, 2,2,5,7,8-pentamethyl-6-hydroxy chromane, by ascorbate/dihydrolipoate in living HL-60 cells.
Journal: Biochimica et biophysica acta20030317
Title: Antioxidant action of 2,2,4,6-tetra-substituted 2,3-dihydro-5-hydroxybenzofuran against lipid peroxidation: effects of substituents and side chain.
Journal: Free radical research20021101
Title: Naphthalene diols: a new class of antioxidants intramolecular hydrogen bonding in catechols, naphthalene diols, and their aryloxyl radicals.
Journal: The Journal of organic chemistry20020726
Title: Antithrombotic effect of PMC, a potent alpha-tocopherol analogue on platelet plug formation in vivo.
Journal: British journal of haematology20020601
Title: Reduction of 8a-hydroxy-2,2,5,7,8-pentamethyl-6-chromanone.
Journal: Redox report : communications in free radical research20020101
Title: Cellular basis for complex T waves and arrhythmic activity following combined I(Kr) and I(Ks) block.
Journal: Journal of cardiovascular electrophysiology20011201
Title: Pharmacokinetics and metabolism of a cysteinyl leukotriene-1 receptor antagonist from the heterocyclic chromanol series in rats: in vitro-in vivo correlation, gender-related differences, isoform identification, and comparison with metabolism in human hepatic tissue.
Journal: Drug metabolism and disposition: the biological fate of chemicals20011101
Title: Ionic basis for membrane potential changes induced by hypoosmotic stress in guinea-pig ventricular myocytes.
Journal: Cardiovascular research20010701
Title: Diesel exhaust particle-induced cell death of human leukemic promyelocytic cells HL-60 and their variant cells HL-NR6.
Journal: Biological & pharmaceutical bulletin20010401
Title: Co-oxidation of 2,2,5,7,8-pentamethyl-6-chromanol and diphenyl disulfide with 3-chloroperoxybenzoic acid.
Journal: Redox report : communications in free radical research20010101
Title: Antioxidant activity of 5-alkoxymethyl-6-chromanols.
Journal: Redox report : communications in free radical research20010101
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