99495-90-6,MFCD00869713
Catalog No.:AA01E9DW

99495-90-6 | R-(-)-Flecainide

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Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$292.00   $204.00
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Technical Information
Catalog Number:
AA01E9DW
Chemical Name:
R-(-)-Flecainide
CAS Number:
99495-90-6
Molecular Formula:
C17H20F6N2O3
Molecular Weight:
414.3427
MDL Number:
MFCD00869713
SMILES:
O=C(c1cc(OCC(F)(F)F)ccc1OCC(F)(F)F)NC[C@H]1CCCCN1
Properties
Computed Properties
 
Complexity:
500  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
28  
Hydrogen Bond Acceptor Count:
10  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0  
Rotatable Bond Count:
7  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
3.8  

Literature

Title: CYP2D6 genotype affects age-related decline in flecainide clearance: a population pharmacokinetic analysis.

Journal: Pharmacogenetics and genomics 20121101

Title: Spinal blockades of class I antiarrythmic drugs with bupivacaine by isobolographic analysis in rats.

Journal: Neuroscience letters 20121018

Title: R222Q SCN5A mutation is associated with reversible ventricular ectopy and dilated cardiomyopathy.

Journal: Journal of the American College of Cardiology 20121016

Title: [New antiarrhythmic drugs for the treatment of atrial fibrillation].

Journal: Giornale italiano di cardiologia (2006) 20121001

Title: ACP Journal Club. Short-term was less effective than long-term flecainide for preventing recurrent AF after cardioversion.

Journal: Annals of internal medicine 20120918

Title: Impact of Na⁺ channel blockers on transmural dispersion of refractoriness and arrhythmic susceptibility in guinea-pig left ventricle.

Journal: European journal of pharmacology 20120915

Title: Modeling of catecholaminergic polymorphic ventricular tachycardia with patient-specific human-induced pluripotent stem cells.

Journal: Journal of the American College of Cardiology 20120911

Title: The role of the anaesthetised guinea-pig in the preclinical cardiac safety evaluation of drug candidate compounds.

Journal: Toxicology and applied pharmacology 20120901

Title: Sodium current deficit and arrhythmogenesis in a murine model of plakophilin-2 haploinsufficiency.

Journal: Cardiovascular research 20120901

Title: Rapid control of foetal supraventricular tachycardia with digoxin and flecainide combination treatment.

Journal: Cardiology in the young 20120801

Title: The long and short of antiarrhythmic drug treatment.

Journal: Lancet (London, England) 20120721

Title: Short-term versus long-term antiarrhythmic drug treatment after cardioversion of atrial fibrillation (Flec-SL): a prospective, randomised, open-label, blinded endpoint assessment trial.

Journal: Lancet (London, England) 20120721

Title: Effects of ventricular pacing protocol on electrical restitution assessments in guinea-pig heart.

Journal: Experimental physiology 20120701

Title: Flecainide suppresses defibrillator-induced storming in catecholaminergic polymorphic ventricular tachycardia.

Journal: Pacing and clinical electrophysiology : PACE 20120701

Title: [Supraventricular extrasystole after cardioversion with amiodarone].

Journal: Deutsche medizinische Wochenschrift (1946) 20120701

Title: Brugada pattern masquerading as ST-segment elevation myocardial infarction in flecainide toxicity.

Journal: Indian heart journal 20120701

Title: [Arrhythmic storm in a patient with Brugada syndrome--an unusual case].

Journal: Harefuah 20120701

Title: Feasibility and efficacy of minimally invasive stand-alone surgical ablation of atrial fibrillation. A single-center experience.

Journal: Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing 20120601

Title: Does terfenadine-induced ventricular tachycardia/fibrillation directly relate to its QT prolongation and Torsades de Pointes?

Journal: British journal of pharmacology 20120601

Title: Should all individuals with a nondiagnostic Brugada-electrocardiogram undergo sodium-channel blocker test?

Journal: Heart rhythm 20120601

Title: Nonlinearity between action potential alternans and restitution, which both predict ventricular arrhythmic properties in Scn5a+/- and wild-type murine hearts.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20120601

Title: Chloroquine terminates stretch-induced atrial fibrillation more effectively than flecainide in the sheep heart.

Journal: Circulation. Arrhythmia and electrophysiology 20120601

Title: Letter by Uzun et al regarding article, 'comparison of transplacental treatment of fetal supraventricular tachyarrhythmias with digoxin, flecainide, and sotalol: results of a nonrandomized multicenter study'.

Journal: Circulation 20120522

Title: [Severe acute flecainide intoxication].

Journal: Medicina clinica 20120512

Title: Field and action potential recordings in heart slices: correlation with established in vitro and in vivo models.

Journal: British journal of pharmacology 20120501

Title: SCN1Bb R214Q found in 3 patients: 1 with Brugada syndrome and 2 with lone atrial fibrillation.

Journal: Heart rhythm 20120501

Title: The App-Runx1 region is critical for birth defects and electrocardiographic dysfunctions observed in a Down syndrome mouse model.

Journal: PLoS genetics 20120501

Title: Capture of the volatile carbonyl metabolite of flecainide on 2,4-dinitrophenylhydrazine cartridge for quantitation by stable-isotope dilution mass spectrometry coupled with chromatography.

Journal: Journal of chromatography. A 20120406

Title: Atrial fibrillation with a giant left atrial appendage can be successfully treated with pulmonary vein antrum isolation.

Journal: Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation 20120401

Title: Follow-up with exercise test of effort-induced ventricular arrhythmias linked to ryanodine receptor type 2 gene mutations.

Journal: The American journal of cardiology 20120401

Title: Effects of a novel amiodarone-like compound SAR114646A on the pig atrium and susceptibility to ventricular fibrillation in dogs and pigs.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20120401

Title: Systematic review and meta-analysis of the efficacy of cardioversion by vernakalant and comparators in patients with atrial fibrillation.

Journal: Cardiovascular drugs and therapy 20120401

Title: Convulsions after normal dose of lidocaine: a probable drug interaction.

Journal: British journal of anaesthesia 20120401

Title: Sudden cardiac death and inherited channelopathy: the basic electrophysiology of the myocyte and myocardium in ion channel disease.

Journal: Heart (British Cardiac Society) 20120401

Title: Safety of flecainide.

Journal: Drug safety 20120401

Title: Antiarrhythmic drugs for the maintenance of sinus rhythm: risks and benefits.

Journal: International journal of cardiology 20120322

Title: Pathophysiology of the cardiac late Na current and its potential as a drug target.

Journal: Journal of molecular and cellular cardiology 20120301

Title: A liquid chromatography-electrospray tandem mass spectrometry method for the determination of antiarrhythmic drugs and their metabolites in forensic whole blood samples.

Journal: Journal of analytical toxicology 20120301

Title: Therapeutic approach for patients with catecholaminergic polymorphic ventricular tachycardia: state of the art and future developments.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20120201

Title: Guidelines for the diagnosis and management of Catecholaminergic Polymorphic Ventricular Tachycardia.

Journal: Heart, lung & circulation 20120201

Title: Catecholaminergic polymorphic ventricular tachycardia in a patient with recurrent exertional syncope.

Journal: Korean circulation journal 20120201

Title: Atrial flutter in normal heart could be first manifestation of Brugada syndrome.

Journal: Acta cardiologica 20120201

Title: Flecainide and antiarrhythmic effects in a mouse model of catecholaminergic polymorphic ventricular tachycardia.

Journal: Trends in cardiovascular medicine 20120201

Title: Effects of CYP2D6*10, CYP3A5*3, CYP1A2*1F, and ABCB1 C3435T polymorphisms on the pharmacokinetics of flecainide in healthy Chinese subjects.

Journal: Drug metabolism and drug interactions 20120109

Title: Successful elimination of significant arrhythmia burden with flecainide in an adolescent with long QT syndrome type 3.

Journal: Congenital heart disease 20120101

Title: Dronedarone for the treatment of atrial fibrillation: a NICE single technology appraisal.

Journal: PharmacoEconomics 20120101

Title: Usefulness of postmortem biochemistry in forensic pathology: illustrative case reports.

Journal: Legal medicine (Tokyo, Japan) 20120101

Title: The effects of a bidirectional cavo-tricuspid isthmus block in persistent atrial fibrillation.

Journal: Yonsei medical journal 20120101

Title: Ionic mechanisms of desflurane on prolongation of action potential duration in rat ventricular myocytes.

Journal: Yonsei medical journal 20120101

Title: Skin biopsy-proven flecainide-induced neuropathy.

Journal: Muscle & nerve 20120101

Title: Pharmacological interventions in the treatment of the acute effects of cannabis: a systematic review of literature.

Journal: Harm reduction journal 20120101

Title: Tinnitus: network pathophysiology-network pharmacology.

Journal: Frontiers in systems neuroscience 20120101

Title: Trends in qualifying biomarkers in drug safety. Consensus of the 2011 meeting of the spanish society of clinical pharmacology.

Journal: Frontiers in pharmacology 20120101

Title: Cardiac Safety Implications of hNav1.5 Blockade and a Framework for Pre-Clinical Evaluation.

Journal: Frontiers in pharmacology 20120101

Title: Macrocephaly-capillary malformation presenting with fetal arrhythmia.

Journal: Pediatric dermatology 20120101

Title: Identification of putative potassium channel homologues in pathogenic protozoa.

Journal: PloS one 20120101

Title: Molecular Insights into the Local Anesthetic Receptor within Voltage-Gated Sodium Channels Using Hydroxylated Analogs of Mexiletine.

Journal: Frontiers in pharmacology 20120101

Title: Cost considerations in the management of atrial fibrillation - impact of dronedarone.

Journal: ClinicoEconomics and outcomes research : CEOR 20120101

Title: Congenital giant cardiac tumor with severe left-ventricular inflow and outflow obstruction and arrhythmia treated with pulmonary artery banding and long-term amiodarone infusion.

Journal: Annals of pediatric cardiology 20120101

Title: Mexiletine differentially restores the trafficking defects caused by two brugada syndrome mutations.

Journal: Frontiers in pharmacology 20120101

Title: Omega-3 Fatty acids: anti-arrhythmic, pro-arrhythmic, or both?

Journal: Frontiers in physiology 20120101

Title: Bidirectional ventricular tachycardia: a hallmark of catecholaminergic polymorphic ventricular tachycardia.

Journal: Indian pacing and electrophysiology journal 20120101

Title: Expression of ABC Efflux transporters in placenta from women with insulin-managed diabetes.

Journal: PloS one 20120101

Title: Diagnostic dilemmas: overlapping features of brugada syndrome and arrhythmogenic right ventricular cardiomyopathy.

Journal: Frontiers in physiology 20120101

Title: A linear ablating system in the left and right atrium: feasibility, catheter performance and clinical results.

Journal: Indian pacing and electrophysiology journal 20120101

Title: Is the measurement of accessory pathway refractory period reproducible?

Journal: Indian pacing and electrophysiology journal 20120101

Title: Effects of flecainide therapy on inappropriate shocks and arrhythmias in catecholaminergic polymorphic ventricular tachycardia.

Journal: Journal of electrocardiology 20120101

Title: Decreased milk drinking causing flecainide toxicity in an older child.

Journal: BMJ case reports 20120101

Title: A misguided 'pill in the pocket' approach with flecainide leading to cardiac arrest.

Journal: BMJ case reports 20120101

Title: [Is the determination of the defibrillation threshold in patients with an implantable cardioverter-defibrillator still required?].

Journal: Herzschrittmachertherapie & Elektrophysiologie 20111201

Title: The management of patients with atrial fibrillation and dronedarone's place in therapy.

Journal: Advances in therapy 20111201

Title: Medical reversal: why we must raise the bar before adopting new technologies.

Journal: The Yale journal of biology and medicine 20111201

Title: Class I antiarrhythmic drugs produced a spinal anesthetic effect in rats.

Journal: Neuroscience letters 20111114

Title: New drugs vs. old concepts: a fresh look at antiarrhythmics.

Journal: Pharmacology & therapeutics 20111101

Title: Rationale and current perspective for early rhythm control therapy in atrial fibrillation.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20111101

Title: Efficacy and potency of class I antiarrhythmic drugs for suppression of Ca2+ waves in permeabilized myocytes lacking calsequestrin.

Journal: Journal of molecular and cellular cardiology 20111101

Title: K201 (JTV-519) alters the spatiotemporal properties of diastolic Ca(2+) release and the associated diastolic contraction during β-adrenergic stimulation in rat ventricular cardiomyocytes.

Journal: Basic research in cardiology 20111101

Title: Pharmacological conversion of recent atrial fibrillation: a randomized, placebo-controlled study of three antiarrhythmic drugs.

Journal: Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology 20111101

Title: Fever-induced QTc prolongation and ventricular fibrillation in a healthy young man.

Journal: Yonsei medical journal 20111101

Title: [Catheter ablation of paroxysmal atrial fibrillation: extended recommendations considering safety improvements of pulmonary vein isolation with a cryoballoon--Case 11/2011].

Journal: Deutsche medizinische Wochenschrift (1946) 20111101

Title: Comparison of transplacental treatment of fetal supraventricular tachyarrhythmias with digoxin, flecainide, and sotalol: results of a nonrandomized multicenter study.

Journal: Circulation 20111018

Title: Pharmacological inhibition of the hERG potassium channel is modulated by extracellular but not intracellular acidosis.

Journal: Journal of cardiovascular electrophysiology 20111001

Title: Management of atrial fibrillation by primary care physicians in Germany: baseline results of the ATRIUM registry.

Journal: Clinical research in cardiology : official journal of the German Cardiac Society 20111001

Title: Postpacing abnormal repolarization in catecholaminergic polymorphic ventricular tachycardia associated with a mutation in the cardiac ryanodine receptor gene.

Journal: Heart rhythm 20111001

Title: Refractory dispersion promotes conduction disturbance and arrhythmias in a Scn5a (+/-) mouse model.

Journal: Pflugers Archiv : European journal of physiology 20111001

Title: Syncope following 'pill-in-the-pocket' treatment of atrial fibrillation with propafenone plus quinidine.

Journal: Heart (British Cardiac Society) 20111001

Title: [Remodeling by atrial fibrillation and clinical implications for cardioversion].

Journal: Deutsche medizinische Wochenschrift (1946) 20111001

Title: A novel N440K sodium channel mutation causes myotonia with exercise-induced weakness--exclusion of CLCN1 exon deletion/duplication by MLPA.

Journal: Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology 20111001

Title: Mechanism of antiarrhythmic effects of flecainide in catecholaminergic polymorphic ventricular tachycardia.

Journal: Circulation research 20110902

Title: Managing patients with ICD shocks and programming tachycardia therapies during acute heart failure syndromes.

Journal: Heart failure reviews 20110901

Title: Type I Brugada electrocardiogram pattern induced by metoclopramide.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20110901

Title: The safety of flecainide treatment of atrial fibrillation: long-term incidence of sudden cardiac death and proarrhythmic events.

Journal: Journal of internal medicine 20110901

Title: Update on anti-coagulation in atrial fibrillation.

Journal: QJM : monthly journal of the Association of Physicians 20110901

Title: Atypical response of class IC atrial flutter to adenosine.

Journal: Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace 20110901

Title: A computational model to predict the effects of class I anti-arrhythmic drugs on ventricular rhythms.

Journal: Science translational medicine 20110831

Title: Cardiovascular MRI in clinical trials: expanded applications through novel surrogate endpoints.

Journal: Heart (British Cardiac Society) 20110815

Title: Two candidates at the heart of dysfunction: The ryanodine receptor and calcium/calmodulin protein kinase II as potential targets for therapeutic intervention-An in vivo perspective.

Journal: Pharmacology & therapeutics 20110801

Title: Impact of dronedarone on hospitalization burden in patients with atrial fibrillation: results from the ATHENA study.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20110801

Title: Is antiarrhythmic treatment in the elderly different? a review of the specific changes.

Journal: Drugs & aging 20110801

Title: Does a Brugada pattern ECG precipitated by excessive-dose flecainide provide a diagnosis of a Brugada syndrome patient and/or contraindicate its use? A case study.

Journal: Circulation. Arrhythmia and electrophysiology 20110801

Title: Short communication: flecainide exerts an antiarrhythmic effect in a mouse model of catecholaminergic polymorphic ventricular tachycardia by increasing the threshold for triggered activity.

Journal: Circulation research 20110722

Title: Natural history and outcome of hepatic vascular malformations in a large cohort of patients with hereditary hemorrhagic teleangiectasia.

Journal: Digestive diseases and sciences 20110701

Title: Perinatal treatment of refractory atrial flutter with hydrops fetalis: a case report.

Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20110701

Title: Use of intravenous lipid 20% emulsion for the treatment of a voluntary intoxication of flecainide with refractory shock.

Journal: Clinical toxicology (Philadelphia, Pa.) 20110701

Title: A 2-year survey of treatment of acute atrial fibrillation in an ED.

Journal: The American journal of emergency medicine 20110601

Title: Successful treatment of catecholaminergic polymorphic ventricular tachycardia with flecainide: a case report and review of the current literature.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20110601

Title: Prevalence of electrocardiographic findings suggestive of sudden cardiac death risk in 10,867 apparently healthy young Korean men.

Journal: Pacing and clinical electrophysiology : PACE 20110601

Title: Flecainide therapy reduces exercise-induced ventricular arrhythmias in patients with catecholaminergic polymorphic ventricular tachycardia.

Journal: Journal of the American College of Cardiology 20110531

Title: A novel mechanism for LQT3 with 2:1 block: a pore-lining mutation in Nav1.5 significantly affects voltage-dependence of activation.

Journal: Heart rhythm 20110501

Title: The ryanodine receptor: a pivotal Ca2+ regulatory protein and potential therapeutic drug target.

Journal: Current drug targets 20110501

Title: Mapping of reentrant spontaneous polymorphic ventricular tachycardia in a Scn5a+/- mouse model.

Journal: American journal of physiology. Heart and circulatory physiology 20110501

Title: Genetics of sudden cardiac death syndromes.

Journal: Current opinion in cardiology 20110501

Title: Inhibition of cardiac Ca2+ release channels (RyR2) determines efficacy of class I antiarrhythmic drugs in catecholaminergic polymorphic ventricular tachycardia.

Journal: Circulation. Arrhythmia and electrophysiology 20110401

Title: Comparison of the in vivo hemodynamic effects of the antiarrhythmic agents vernakalant and flecainide in a rat hindlimb perfusion model.

Journal: Journal of cardiovascular pharmacology 20110401

Title: Flecainide.

Journal: Acta cardiologica 20110401

Title: [Brugada electrocardiographic pattern elicited by flecainide overdose].

Journal: Medicina clinica 20110319

Title: Quantitative trait loci for electrocardiographic parameters and arrhythmia in the mouse.

Journal: Journal of molecular and cellular cardiology 20110301

Title: Na+ channel distribution and electrophysiological heterogeneities in guinea pig ventricular wall.

Journal: American journal of physiology. Heart and circulatory physiology 20110301

Title: Mixed treatment comparison of dronedarone, amiodarone, sotalol, flecainide, and propafenone, for the management of atrial fibrillation.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20110301

Title: Mixed treatment comparisons for atrial fibrillation: evidence network or bewildering entanglement?

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20110301

Title: A possible association between takotsubo cardiomyopathy and treatment with flecainide.

Journal: International journal of cardiology 20110217

Title: Spatial and temporal heterogeneities are localized to the right ventricular outflow tract in a heterozygotic Scn5a mouse model.

Journal: American journal of physiology. Heart and circulatory physiology 20110201

Title: Twenty-five years in the making: flecainide is safe and effective for the management of atrial fibrillation.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20110201

Title: Biophysical and molecular characterization of a novel de novo KCNJ2 mutation associated with Andersen-Tawil syndrome and catecholaminergic polymorphic ventricular tachycardia mimicry.

Journal: Circulation. Cardiovascular genetics 20110201

Title: Flecainide acetate acetic acid solvates.

Journal: Journal of pharmaceutical sciences 20110201

Title: Emergency treatment of Wolff-Parkinson-White syndrome.

Journal: Emergency nurse : the journal of the RCN Accident and Emergency Nursing Association 20110201

Title: ST-segment elevation in a patient receiving flecainide.

Journal: Archives of internal medicine 20110110

Title: Pacemaker malfunction induced by a pharmaco-metabolic 'perfect storm': a brief report.

Journal: Journal of clinical pharmacology 20110101

Title: Efficacy of flecainide in a patient with catecholaminergic polymorphic ventricular tachycardia.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20110101

Title: Catecholaminergic polymorphic ventricular tachycardia: important messages from case reports.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20110101

Title: Electrophysiologic studies and radiofrequency catheter ablation of ectopic atrial tachycardia in children.

Journal: Pediatric cardiology 20110101

Title: Risk stratification in individuals with the Brugada type 1 ECG pattern without previous cardiac arrest: usefulness of a combined clinical and electrophysiologic approach.

Journal: European heart journal 20110101

Title: Delayed conduction and its implications in murine Scn5a(+/-) hearts: independent and interacting effects of genotype, age, and sex.

Journal: Pflugers Archiv : European journal of physiology 20110101

Title: [Acute flecainide overdose].

Journal: Anales de pediatria (Barcelona, Spain : 2003) 20110101

Title: A Case of Isolated Left Ventricular Noncompaction with Basal ECG-Tracing Strongly Suggestive for Type-2 Brugada Syndrome.

Journal: Cardiology research and practice 20110101

Title: Translation of flecainide- and mexiletine-induced cardiac sodium channel inhibition and ventricular conduction slowing from nonclinical models to clinical.

Journal: Journal of pharmacological and toxicological methods 20110101

Title: Dronedarone: current evidence for its safety and efficacy in the management of atrial fibrillation.

Journal: Drug design, development and therapy 20110101

Title: Familial Takayasu arteritis - a pediatric case and a review of the literature.

Journal: Pediatric rheumatology online journal 20110101

Title: Impact of sarcoplasmic reticulum calcium release on calcium dynamics and action potential morphology in human atrial myocytes: a computational study.

Journal: PLoS computational biology 20110101

Title: Canadian Cardiovascular Society atrial fibrillation guidelines 2010: rate and rhythm management.

Journal: The Canadian journal of cardiology 20110101

Title: Mitochondria as crucial players in demyelinated axons: lessons from neuropathology and experimental demyelination.

Journal: Autoimmune diseases 20110101

Title: Recapitulation of an ion channel IV curve using frequency components.

Journal: Journal of visualized experiments : JoVE 20110101

Title: An Observational, Prospective Survey Assessing the Control of Atrial Fibrillation in Asia Pacific: Rationale and Design of the RecordAF-AP Registry.

Journal: Clinical Medicine Insights. Cardiology 20110101

Title: Sex differences in drug disposition.

Journal: Journal of biomedicine & biotechnology 20110101

Title: Endurance exercise training reduces cardiac sodium/calcium exchanger expression in animals susceptible to ventricular fibrillation.

Journal: Frontiers in physiology 20110101

Title: Left superior pulmonary vein rhythm masquerading as sinus rhythm.

Journal: Indian pacing and electrophysiology journal 20110101

Title: Atrial fibrillation and the use of oral bisphosphonates.

Journal: Therapeutics and clinical risk management 20110101

Title: The pathology and treatment of cardiac arrhythmias: focus on atrial fibrillation.

Journal: Vascular health and risk management 20110101

Title: Pharmacological management of atrial fibrillation: one, none, one hundred thousand.

Journal: Cardiology research and practice 20110101

Title: Recent advances in the pathogenesis and drug action in periodic paralyses and related channelopathies.

Journal: Frontiers in pharmacology 20110101

Title: Atrial fibrillation (acute onset).

Journal: BMJ clinical evidence 20110101

Title: Pharmacodynamic and Pharmacokinetic Interactions of Propranolol with Garlic (Allium sativum) in Rats.

Journal: Evidence-based complementary and alternative medicine : eCAM 20110101

Title: Depression in vascular pathologies: the neurologist's point of view.

Journal: Vascular health and risk management 20110101

Title: Perioperative atrial fibrillation in five patients - role of anxiety.

Journal: Journal of anaesthesiology, clinical pharmacology 20110101

Title: Torsades de pointes during laparoscopic adrenalectomy of a pheochromocytoma: a case report.

Journal: Journal of medical case reports 20110101

Title: Management of patients with atrial fibrillation: specific considerations for the old age.

Journal: Cardiology research and practice 20110101

Title: Mechanism underlying catecholaminergic polymorphic ventricular tachycardia and approaches to therapy.

Journal: Journal of electrocardiology 20110101

Title: Incidence and severity of coronary artery disease in patients with atrial fibrillation undergoing first-time coronary angiography.

Journal: PloS one 20110101

Title: Utility of frozen cell lines in medium throughput electrophysiology screening of hERG and NaV1.5 blockade.

Journal: Journal of pharmacological and toxicological methods 20110101

Title: Na Channel β Subunits: Overachievers of the Ion Channel Family.

Journal: Frontiers in pharmacology 20110101

Title: Skeletal muscle na channel disorders.

Journal: Frontiers in pharmacology 20110101

Title: The sodium channel as a target for local anesthetic drugs.

Journal: Frontiers in pharmacology 20110101

Title: Targeting GIRK Channels for the Development of New Therapeutic Agents.

Journal: Frontiers in pharmacology 20110101

Title: Safety and efficacy of dronedarone in the treatment of atrial fibrillation/flutter.

Journal: Clinical Medicine Insights. Cardiology 20110101

Title: Right ventricular dysfunction in patients with Brugada-like electrocardiography: a two dimensional strain imaging study.

Journal: Cardiovascular ultrasound 20110101

Title: A patient with mexiletine-related psychosis.

Journal: International journal of general medicine 20110101

Title: New methods for the analysis of heartbeat behavior in risk stratification.

Journal: Frontiers in physiology 20110101

Title: 'Wait and see' approach to the emergency department cardioversion of acute atrial fibrillation.

Journal: Emergency medicine international 20110101

Title: [Congenital junctional ectopic tachycardia. Pharmacologic management during infancy].

Journal: Medicina 20110101

Title: The importance of being profiled: improving drug candidate safety and efficacy using ion channel profiling.

Journal: Frontiers in pharmacology 20110101

Title: Automatic continuous ECG monitoring system for over-drug detection in Brugada Syndrome.

Journal: Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference 20110101

Title: Discovery, characterization, and structure-activity relationships of an inhibitor of inward rectifier potassium (Kir) channels with preference for Kir2.3, Kir3.x, and Kir7.1.

Journal: Frontiers in pharmacology 20110101

Title: Genetic Polymorphisms as Risk Stratification Tool in Primary Preventive ICD Therapy.

Journal: ISRN cardiology 20110101

Title: Knock-in gain-of-function sodium channel mutation prolongs atrial action potentials and alters atrial vulnerability.

Journal: Heart rhythm 20101201

Title: Iatrogenic Flecainide toxicity.

Journal: Heart (British Cardiac Society) 20101201

Title: Development of multifocal atrial tachycardia in a patient using aminophylline -A case report-.

Journal: Korean journal of anesthesiology 20101201

Title: Neuronal injury in chronic CNS inflammation.

Journal: Best practice & research. Clinical anaesthesiology 20101201

Title: Incessant tachycardia following posteroseptal pathway ablation: a pseudo-r' or pseudo-pseudo-r' wave in V1?

Journal: Pacing and clinical electrophysiology : PACE 20101101

Title: Optimizing catecholaminergic polymorphic ventricular tachycardia therapy in calsequestrin-mutant mice.

Journal: Heart rhythm 20101101

Title: Safety and efficacy of flecainide in the treatment of symptomatic children with Wolff-Parkinson-White syndrome.

Journal: Pediatric cardiology 20101101

Title: LQTS gene LOVD database.

Journal: Human mutation 20101101

Title: Radiofrequency ablation of coronary sinus-dependent atrial flutter guided by fractionated mid-diastolic coronary sinus potentials.

Journal: Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing 20101101

Title: Effectiveness of prophylactic implantation of cardioverter-defibrillators without cardiac resynchronization therapy in patients with ischaemic or non-ischaemic heart disease: a systematic review and meta-analysis.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20101101

Title: [Flecainide poisoning].

Journal: Revista espanola de anestesiologia y reanimacion 20101101

Title: Small dose... big poison.

Journal: Australian family physician 20101101

Title: Warfarin toxicity and individual variability-clinical case.

Journal: Toxins 20101101

Title: Overlapping binding sites of structurally different antiarrhythmics flecainide and propafenone in the subunit interface of potassium channel Kv2.1.

Journal: The Journal of biological chemistry 20101029

Title: Extracorporeal life support in a case of fatal flecainide and betaxolol poisoning allowing successful cardiac allograft.

Journal: Annals of emergency medicine 20101001

Title: Regional variations in action potential alternans in isolated murine Scn5a (+/-) hearts during dynamic pacing.

Journal: Acta physiologica (Oxford, England) 20101001

Title: Increased right ventricular repolarization gradients promote arrhythmogenesis in a murine model of Brugada syndrome.

Journal: Journal of cardiovascular electrophysiology 20101001

Title: Atrial arrhythmogenic properties in wild-type and Scn5a+/- murine hearts.

Journal: Experimental physiology 20101001

Title: 'Pill-in-the-pocket' treatment for recent-onset atrial fibrillation.

Journal: Heart (British Cardiac Society) 20101001

Title: Management of patients with acute atrial fibrillation in the ED.

Journal: The American journal of emergency medicine 20101001

Title: Dronedarone for the treatment of atrial fibrillation and atrial flutter.

Journal: Health technology assessment (Winchester, England) 20101001

Title: State of the art in hereditary muscle channelopathies.

Journal: Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology 20101001

Title: Flecainide inhibits the stimulatory effect of veratridine on the response of airway mechanoreceptors to maintained inflations in rats.

Journal: Life sciences 20100925

Title: In vivo studies of Scn5a+/- mice modeling Brugada syndrome demonstrate both conduction and repolarization abnormalities.

Journal: Journal of electrocardiology 20100901

Title: A transthoracic echocardiographic follow-up study after catheter ablation of atrial fibrillation: can we detect pulmonary vein stenosis by transthoracic echocardiography?

Journal: Korean circulation journal 20100901

Title: Chronic progressive multiple sclerosis - pathogenesis of neurodegeneration and therapeutic strategies.

Journal: Current neuropharmacology 20100901

Title: Computational modelling of the initiation and development of spontaneous intracellular Ca2+ waves in ventricular myocytes.

Journal: Philosophical transactions. Series A, Mathematical, physical, and engineering sciences 20100828

Title: Purkinje cells from RyR2 mutant mice are highly arrhythmogenic but responsive to targeted therapy.

Journal: Circulation research 20100820

Title: Effects of flecainide and quinidine on action potential and ventricular arrhythmogenic properties in Scn3b knockout mice.

Journal: Clinical and experimental pharmacology & physiology 20100801

Title: Pharmacological activation of IKr impairs conduction in guinea pig hearts.

Journal: Journal of cardiovascular electrophysiology 20100801

Title: Atrial arrhythmogenicity in aged Scn5a+/DeltaKPQ mice modeling long QT type 3 syndrome and its relationship to Na+ channel expression and cardiac conduction.

Journal: Pflugers Archiv : European journal of physiology 20100801

Title: Liquid chromatographic direct resolution of flecainide and its analogs on a chiral stationary phase based on (+)-(18-crown-6)-2,3,11,12-tetracarboxylic acid.

Journal: Chirality 20100701

Title: Cardiac sodium channelopathies.

Journal: Pflugers Archiv : European journal of physiology 20100701

Title: Autonomic modulation and antiarrhythmic therapy in a model of long QT syndrome type 3.

Journal: Cardiovascular research 20100701

Title: Sodium channelopathies of skeletal muscle result from gain or loss of function.

Journal: Pflugers Archiv : European journal of physiology 20100701

Title: Rhythm control agents and adverse events in patients with atrial fibrillation.

Journal: International journal of clinical practice 20100701

Title: Molecular determinants of state-dependent block of voltage-gated sodium channels by pilsicainide.

Journal: British journal of pharmacology 20100701

Title: The spectrum of SCN5A gene mutations in Spanish Brugada syndrome patients.

Journal: Revista espanola de cardiologia 20100701

Title: Successful thrombolytic therapy with recombinant tissue-type plasminogen activator for massive pulmonary embolism -A case report-.

Journal: Korean journal of anesthesiology 20100701

Title: Arrhythmic risk biomarkers for the assessment of drug cardiotoxicity: from experiments to computer simulations.

Journal: Philosophical transactions. Series A, Mathematical, physical, and engineering sciences 20100628

Title: Flecainide for cardioversion in patients at elevated cardiovascular risk and persistent atrial fibrillation: a prospective observational study.

Journal: Clinical research in cardiology : official journal of the German Cardiac Society 20100601

Title: Congenital long QT syndrome and 2:1 atrioventricular block: an optimistic outcome in the current era.

Journal: Heart rhythm 20100601

Title: Substrate and Trigger Ablation for Reduction of Atrial Fibrillation (STAR AF): a randomized, multicentre, international trial.

Journal: European heart journal 20100601

Title: Management of persistent wide QRS in flecainide overdose with magnesium sulphate.

Journal: Emergency medicine journal : EMJ 20100601

Title: A mathematical model to understand the mechanisms of action of class 1 antiarrhythmic drugs.

Journal: Indian journal of pharmacology 20100601

Title: Impact of the control of symptomatic paroxysmal atrial fibrillation on health-related quality of life.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20100501

Title: Predicting drug-induced slowing of conduction and pro-arrhythmia: identifying the 'bad' sodium current blockers.

Journal: British journal of pharmacology 20100501

Title: Increase in organization index predicts atrial fibrillation termination with flecainide post-ablation: spectral analysis of intracardiac electrograms.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20100401

Title: Termination of atrial fibrillation by flecainide: mechanistic insights from spectral analysis.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20100401

Title: Intravenous administration of flecainide or propafenone in patients with recent-onset atrial fibrillation does not predict adverse effects during 'pill-in-the-pocket' treatment.

Journal: Heart (British Cardiac Society) 20100401

Title: Changes in the QTc interval after administration of flecainide acetate, with and without coadministered paroxetine, in relation to cytochrome P450 2D6 genotype: data from an open-label, two-period, single-sequence crossover study in healthy Korean male subjects.

Journal: Clinical therapeutics 20100401

Title: Tachycardia due to atrial flutter with rapid 1:1 conduction following treatment of atrial fibrillation with flecainide.

Journal: BMJ (Clinical research ed.) 20100310

Title: Inhibition of IK,ACh current may contribute to clinical efficacy of class I and class III antiarrhythmic drugs in patients with atrial fibrillation.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20100301

Title: Cardioversion of atrial fibrillation: the use of antiarrhythmic drugs.

Journal: Heart (British Cardiac Society) 20100301

Title: Physician stated atrial fibrillation management in light of treatment guidelines: data from an international, observational prospective survey.

Journal: Clinical cardiology 20100301

Title: Childhood brugada syndrome in two korean families.

Journal: Korean circulation journal 20100301

Title: Supraventricular tachyarrhythmia and Brugada syndrome: a case of atrial fibrillation and Brugada syndrome in a young patient without structural heart disease.

Journal: The West Indian medical journal 20100301

Title: [Instead of long-term antiarrhythmia drug treatment--stand-by therapy for atrial fibrillation].

Journal: MMW Fortschritte der Medizin 20100218

Title: Flecainide inhibits arrhythmogenic Ca2+ waves by open state block of ryanodine receptor Ca2+ release channels and reduction of Ca2+ spark mass.

Journal: Journal of molecular and cellular cardiology 20100201

Title: Tpeak-Tend interval and Tpeak-Tend/QT ratio as markers of ventricular tachycardia inducibility in subjects with Brugada ECG phenotype.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20100201

Title: An antidote for calcium leak: targeting molecular arrhythmia mechanisms.

Journal: Journal of molecular and cellular cardiology 20100201

Title: Drug-drug interaction between oxycodone and adjuvant analgesics in blood-brain barrier transport and antinociceptive effect.

Journal: Journal of pharmaceutical sciences 20100101

Title: Postmortem acidification of blood/organs induces an increase in flecainide concentration in cardiac blood and the contribution of the lungs to this increase.

Journal: Journal of analytical toxicology 20100101

Title: Successful use of a rapid response team in the pediatric oncology outpatient setting.

Journal: Joint Commission journal on quality and patient safety 20100101

Title: Congenital short QT syndrome.

Journal: Indian pacing and electrophysiology journal 20100101

Title: Ganglionic plexus ablation during pulmonary vein isolation--predisposing to ventricular arrhythmias?

Journal: Indian pacing and electrophysiology journal 20100101

Title: Lower lid entropion secondary to treatment with alpha-1a receptor antagonist: a case report.

Journal: Journal of medical case reports 20100101

Title: EVITA: a tool for the early evaluation of pharmaceutical innovations with regard to therapeutic advantage.

Journal: BMC clinical pharmacology 20100101

Title: Atypical ST segment elevation and ventricular fibrillation without structural heart disease: a new electrocardiographic presentation of a channelopathy?

Journal: Cardiology 20100101

Title: Reporting bias in medical research - a narrative review.

Journal: Trials 20100101

Title: Systematic reviews, systematic error and the acquisition of clinical knowledge.

Journal: BMC medical research methodology 20100101

Title: Risk stratification in young patients with channelopathies.

Journal: Indian pacing and electrophysiology journal 20100101

Title: Ventricular tachycardia in pregnant patients.

Journal: Clinical Medicine Insights. Cardiology 20100101

Title: Assessing use-dependent inhibition of the cardiac Na(+/-) current (I(Na)) in the PatchXpress automated patch clamp.

Journal: Journal of pharmacological and toxicological methods 20100101

Title: What an emergency physician needs to know about acute care of cardiac arrhythmias.

Journal: Journal of emergencies, trauma, and shock 20100101

Title: Tachyarrhythmias, bradyarrhythmias and acute coronary syndromes.

Journal: Journal of emergencies, trauma, and shock 20100101

Title: Treating critical supraventricular and ventricular arrhythmias.

Journal: Journal of emergencies, trauma, and shock 20100101

Title: Emergency therapy of maternal and fetal arrhythmias during pregnancy.

Journal: Journal of emergencies, trauma, and shock 20100101

Title: Beta1-adrenoceptor polymorphism predicts flecainide action in patients with atrial fibrillation.

Journal: PloS one 20100101

Title: Junctional ectopic tachycardia.

Journal: Indian pacing and electrophysiology journal 20100101

Title: Sodium channel molecular conformations and antiarrhythmic drug affinity.

Journal: Trends in cardiovascular medicine 20100101

Title: Current and emerging therapeutic options for the treatment of chronic chagasic cardiomyopathy.

Journal: Vascular health and risk management 20100101

Title: Amiodarone for the treatment and prevention of ventricular fibrillation and ventricular tachycardia.

Journal: Vascular health and risk management 20100101

Title: Dronedarone for the treatment of atrial fibrillation and atrial flutter: approval and efficacy.

Journal: Vascular health and risk management 20100101

Title: Premature Ventricular Contractions and Non-sustained Ventricular Tachycardia: Association with Sudden Cardiac Death, Risk Stratification, and Management Strategies.

Journal: Indian pacing and electrophysiology journal 20100101

Title: Genetic analysis of Brugada syndrome and congenital long-QT syndrome type 3 in the Chinese.

Journal: Journal of cardiovascular disease research 20100101

Title: Paroxysmal atrial fibrillation due to bronchogenic cyst.

Journal: Internal medicine (Tokyo, Japan) 20100101

Title: Brugada syndrome: Controversies in Risk stratification and Management.

Journal: Indian pacing and electrophysiology journal 20100101

Title: A review of the mechanisms of ventricular arrhythmia in brugada syndrome.

Journal: Indian pacing and electrophysiology journal 20100101

Title: Emergency diagnosis and management of pediatric arrhythmias.

Journal: Journal of emergencies, trauma, and shock 20100101

Title: Classification of drugs based on properties of sodium channel inhibition: a comparative automated patch-clamp study.

Journal: PloS one 20100101

Title: New and emerging therapeutic agents for the treatment of fibromyalgia: an update.

Journal: Journal of pain research 20100101

Title: Sudden cause of cardiac death-be aware of me: a case report and short review on brugada syndrome.

Journal: Case reports in medicine 20100101

Title: General anaesthesia for insertion of an automated implantable cardioverter defibrillator in a child with Brugada and autism.

Journal: Indian journal of anaesthesia 20100101

Title: Sudden cardiac death in children and adolescents (excluding Sudden Infant Death Syndrome).

Journal: Annals of pediatric cardiology 20100101

Title: Challenging cardiac electrophysiology.

Journal: Frontiers in physiology 20100101

Title: Anti- or profibrillatory effects of Na(+) channel blockade depend on the site of application relative to gradients in repolarization.

Journal: Frontiers in physiology 20100101

Title: Stereoselective Inhibition of the hERG1 Potassium Channel.

Journal: Frontiers in pharmacology 20100101

Title: New-onset atrial fibrillation as first clinical manifestation of latent Brugada syndrome: prevalence and clinical significance.

Journal: European heart journal 20091201

Title: What is treatment success in cardiac resynchronization therapy?

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20091101

Title: Pharmacological changes in cellular Ca2+ homeostasis parallel initiation of atrial arrhythmogenesis in murine Langendorff-perfused hearts.

Journal: Clinical and experimental pharmacology & physiology 20091001

Title: A case of flecainide-induced hyponatremia.

Journal: Journal of cardiovascular electrophysiology 20091001

Title: Typical atrial flutter can effectively be treated using single one-minute cryoapplications: results from a repeat electrophysiological study.

Journal: Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing 20091001

Title: Skeletal muscle channelopathies: new insights into the periodic paralyses and nondystrophic myotonias.

Journal: Current opinion in neurology 20091001

Title: Fetal ventricular tachycardia secondary to long QT syndrome treated with maternal intravenous magnesium: case report and review of the literature.

Journal: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 20091001

Title: Persistent idiopathic ventricular tachycardia in a 28-year-old woman.

Journal: Emergency medicine journal : EMJ 20091001

Title: CASH as a mnemonic for indications of sodium bicarbonate for sodium channel blocker intoxication.

Journal: The American journal of emergency medicine 20091001

Title: Evaluation of risk of falls and orthostatic hypotension in older, long-term topical beta-blocker users.

Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20090901

Title: Non-invasive imaging of cardiac activation and recovery.

Journal: Annals of biomedical engineering 20090901

Title: Life-threatening flecainide intoxication in a young child secondary to medication error.

Journal: The Annals of pharmacotherapy 20090901

Title: Electrical storm reversible by isoproterenol infusion in a striking case of early repolarization.

Journal: Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing 20090801

Title: Drug-induced Brugada syndrome.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20090801

Title: Pharmacologic management of atrial fibrillation: established and emerging options.

Journal: Journal of managed care pharmacy : JMCP 20090801

Title: Fetal arrhythmia: prenatal diagnosis and perinatal management.

Journal: The journal of obstetrics and gynaecology research 20090801

Title: Treatment of atrial fibrillation with antiarrhythmic drugs or radiofrequency ablation: two systematic literature reviews and meta-analyses.

Journal: Circulation. Arrhythmia and electrophysiology 20090801

Title: Recent advances in pharmacotherapy of atrial fibrillation.

Journal: Indian journal of pharmacology 20090801

Title: Atrial arrhythmogenesis in wild-type and Scn5a+/delta murine hearts modelling LQT3 syndrome.

Journal: Pflugers Archiv : European journal of physiology 20090701

Title: Antiarrhythmic therapy and risk of death in patients with atrial fibrillation: a nationwide study.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20090701

Title: Hyponatremia: disorder of water, not salt.

Journal: Journal of cardiovascular electrophysiology 20090701

Title: The organic cation transporter, OCTN1, expressed in the human heart, potentiates antagonism of the HERG potassium channel.

Journal: Journal of cardiovascular pharmacology 20090701

Title: Delirium in a patient with toxic flecainide plasma concentrations: the role of a pharmacokinetic drug interaction with paroxetine.

Journal: The Annals of pharmacotherapy 20090701

Title: Multiple monophasic shocks improve electrotherapy of ventricular tachycardia in a rabbit model of chronic infarction.

Journal: Heart rhythm 20090701

Title: Effects of CYP2D6 genotypes on age-related change of flecainide metabolism: involvement of CYP1A2-mediated metabolism.

Journal: British journal of clinical pharmacology 20090701

Title: Effects of antiarrhythmic drugs on the hyperpolarization-activated cyclic nucleotide-gated channel current.

Journal: Journal of pharmacological sciences 20090601

Title: Paroxysmal bidirectional ventricular tachycardia with tachycardiomyopathy in a pregnant woman.

Journal: Acta cardiologica 20090601

Title: Update: A 60-year-old woman with atrial fibrillation.

Journal: JAMA 20090506

Title: Flecainide as first-line treatment for supraventricular tachycardia in newborns.

Journal: Journal of cardiovascular medicine (Hagerstown, Md.) 20090501

Title: Pharmacological characteristics and clinical applications of K201.

Journal: Current clinical pharmacology 20090501

Title: Clinical and arrhythmic outcomes after implantation of a defibrillator for primary prevention of sudden death in patients with post-myocardial infarction cardiomyopathy: The Survey to Evaluate Arrhythmia Rate in High-risk MI patients (SEARCH-MI).

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20090401

Title: The Registry of the German Competence NETwork on Atrial Fibrillation: patient characteristics and initial management.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20090401

Title: A preliminary assessment of the effects of ATI-2042 in subjects with paroxysmal atrial fibrillation using implanted pacemaker methodology.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20090401

Title: Involvement of voltage-gated sodium channels blockade in the analgesic effects of orphenadrine.

Journal: Pain 20090401

Title: Waveform characterization of atrial fibrillation using phase information.

Journal: IEEE transactions on bio-medical engineering 20090401

Title: Flecainide prevents catecholaminergic polymorphic ventricular tachycardia in mice and humans.

Journal: Nature medicine 20090401

Title: Flecainide toxicity in an older adult.

Journal: Journal of the American Geriatrics Society 20090401

Title: Aconite poisoning.

Journal: Clinical toxicology (Philadelphia, Pa.) 20090401

Title: An enhancement of coronary blood flow in a fetus with supraventricular tachycardia.

Journal: Prenatal diagnosis 20090301

Title: Provocation of silence.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20090301

Title: Flecainide overdose causing a Brugada-type pattern on electrocardiogram in a previously well patient.

Journal: The American journal of emergency medicine 20090301

Title: Tinnitus: characteristics, causes, mechanisms, and treatments.

Journal: Journal of clinical neurology (Seoul, Korea) 20090301

Title: Arrhythmogenic actions of the Ca2+ channel agonist FPL-64716 in Langendorff-perfused murine hearts.

Journal: Experimental physiology 20090201

Title: Bullous fixed drug eruption caused by flecainide.

Journal: Journal of the American Academy of Dermatology 20090201

Title: Effects of intrapericardial sotalol and flecainide on transmural atrial electrophysiology and atrial fibrillation.

Journal: Journal of cardiovascular electrophysiology 20090201

Title: A dangerous secret.

Journal: The American journal of medicine 20090201

Title: Surrogate end points and their role in clinical trial.

Journal: Indian journal of pharmacology 20090201

Title: Endurance sport practice as a risk factor for atrial fibrillation and atrial flutter.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20090101

Title: Panoramic imaging reveals basic mechanisms of induction and termination of ventricular tachycardia in rabbit heart with chronic infarction: implications for low-voltage cardioversion.

Journal: Heart rhythm 20090101

Title: Ventricular fibrillation with prominent early repolarization associated with a rare variant of KCNJ8/KATP channel.

Journal: Journal of cardiovascular electrophysiology 20090101

Title: Is flecainide dangerous in long QT-3 patients?

Journal: Pacing and clinical electrophysiology : PACE 20090101

Title: Brugada ECG pattern precipitated by acute pneumonia: a case report.

Journal: Cases journal 20090101

Title: Distinct functional defect of three novel Brugada syndrome related cardiac sodium channel mutations.

Journal: Journal of biomedical science 20090101

Title: Isthmus dependent atrial flutter cycle length correlates with right atrial cross-sectional area.

Journal: Indian pacing and electrophysiology journal 20090101

Title: Clinical pharmacokinetic and pharmacodynamic profile of cinacalcet hydrochloride.

Journal: Clinical pharmacokinetics 20090101

Title: Characterization of voltage-gated potassium channels in human neural progenitor cells.

Journal: PloS one 20090101

Title: Arrhythmogenic right ventricular cardiomyopathy presenting with intra-operative aborted sudden cardiac death and TakotsuboLike left ventricular functional abnormalities.

Journal: Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20090101

Title: Brugada-type ECG pattern in patients treated with oral flecainide for lone atrial fibrillation: is there any clinical implication?

Journal: Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20090101

Title: Extracorporeal life support in severe drug intoxication: a retrospective cohort study of seventeen cases.

Journal: Critical care (London, England) 20090101

Title: CMR findings in patients with hypertrophic cardiomyopathy and atrial fibrillation.

Journal: Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20090101

Title: The use of oral ranolazine to convert new or paroxysmal atrial fibrillation: a review of experience with implications for possible 'pill in the pocket' approach to atrial fibrillation.

Journal: Indian pacing and electrophysiology journal 20090101

Title: Drugs associated with more suicidal ideations are also associated with more suicide attempts.

Journal: PloS one 20090101

Title: Polymorphism of human cytochrome P450 2D6 and its clinical significance: Part I.

Journal: Clinical pharmacokinetics 20090101

Title: A Novel SCN5A Mutation in a Patient with Coexistence of Brugada Syndrome Traits and Ischaemic Heart Disease.

Journal: Case reports in medicine 20090101

Title: Atrial fibrillation in cardiac channelopathies.

Journal: Indian pacing and electrophysiology journal 20090101

Title: Short-term and long-term success of electrical cardioversion in atrial fibrillation in managed care system.

Journal: International archives of medicine 20090101

Title: Electrocardiographic changes in a rare case of flecainide poisoning: a case report.

Journal: Cases journal 20090101

Title: Risk stratification for sudden cardiac death: current approaches and predictive value.

Journal: Current cardiology reviews 20090101

Title: Drugs impact on CYP-450 enzyme family: A pharmacogenetical study of response variation.

Journal: Indian journal of human genetics 20090101

Title: Radiofrequency ablation in an infant with recurrent supraventricular tachycardia and cyanosis.

Journal: Annals of pediatric cardiology 20090101

Title: ECG findings in fatal flecainide intoxication.

Journal: BMJ case reports 20090101

Title: [Treatment of atrial fibrillation in every days practice].

Journal: Der Internist 20081201

Title: Letter by Behr and Camm regarding article, 'Induced Brugada-type electrocardiogram, a sign for imminent malignant arrhythmias'.

Journal: Circulation 20081118

Title: [Current strategies in the treatment of atrial fibrillation].

Journal: Medizinische Klinik (Munich, Germany : 1983) 20081115

Title: Is atrial fibrillation with very short cycle length suitable for ablation? A case report.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20081101

Title: Pharmacokinetic interaction of flecainide and paroxetine in relation to the CYP2D6*10 allele in healthy Korean subjects.

Journal: British journal of clinical pharmacology 20081101

Title: ECGs in the ED.

Journal: Pediatric emergency care 20081101

Title: Physiological consequences of the P2328S mutation in the ryanodine receptor (RyR2) gene in genetically modified murine hearts.

Journal: Acta physiologica (Oxford, England) 20081001

Title: Relationship between subjective symptoms and trans-telephonic ECG findings in patients with symptomatic paroxysmal atrial fibrillation and flutter.

Journal: Journal of cardiology 20081001

Title: A mutation in the sodium channel is responsible for the association of long QT syndrome and familial atrial fibrillation.

Journal: Heart rhythm 20081001

Title: Scn3b knockout mice exhibit abnormal ventricular electrophysiological properties.

Journal: Progress in biophysics and molecular biology 20081001

Title: Effect of prenatal antiarrhythmic treatment on cardiac function in a twin pregnancy.

Journal: Pacing and clinical electrophysiology : PACE 20080901

Title: Lidocaine-induced Brugada syndrome phenotype linked to a novel double mutation in the cardiac sodium channel.

Journal: Circulation research 20080815

Title: Reduction of complex ventricular ectopy and improvement in exercise capacity with flecainide therapy in Andersen-Tawil syndrome.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20080801

Title: The Relationship Between HIV Infection and Cardiovascular Disease.

Journal: Current cardiology reviews 20080801

Title: The E1784K mutation in SCN5A is associated with mixed clinical phenotype of type 3 long QT syndrome.

Journal: The Journal of clinical investigation 20080602

Title: [Drug-related neuropathies: analysis of the French Adverse Drug Reaction Database 1995-2005].

Journal: Presse medicale (Paris, France : 1983) 20080601

Title: Effects of MiRP1 and DPP6 beta-subunits on the blockade induced by flecainide of Kv4.3/KChIP2 channels.

Journal: British journal of pharmacology 20080601

Title: Atrial fibrillation in pregnancy.

Journal: European journal of obstetrics, gynecology, and reproductive biology 20080501

Title: Effects of potassium channel openers in the isolated perfused hypokalaemic murine heart.

Journal: Acta physiologica (Oxford, England) 20080501

Title: Paroxysmal reciprocating supraventricular tachycardia in infants: electrophysiologically guided medical treatment and long-term evolution of the re-entry circuit.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20080501

Title: Treatment of new-onset atrial fibrillation in noncardiac intensive care unit patients: a systematic review of randomized controlled trials.

Journal: Critical care medicine 20080501

Title: Use of bepridil in combination with Ic antiarrhythmic agent in converting persistent atrial fibrillation to sinus rhythm.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20080501

Title: Induced Brugada-type electrocardiogram, a sign for imminent malignant arrhythmias.

Journal: Circulation 20080408

Title: [Bradycardia due to blocked atrial bigeminy: ECG].

Journal: Revue medicale suisse 20080402

Title: Pharmacological separation of early afterdepolarizations from arrhythmogenic substrate in DeltaKPQ Scn5a murine hearts modelling human long QT 3 syndrome.

Journal: Acta physiologica (Oxford, England) 20080401

Title: A case of Commotio cordis in a young child caused by a fall.

Journal: Resuscitation 20080401

Title: Mechanisms underlying increased right ventricular conduction sensitivity to flecainide challenge.

Journal: Cardiovascular research 20080301

Title: The cardiac persistent sodium current: an appealing therapeutic target?

Journal: British journal of pharmacology 20080301

Title: Clinical and electrophysiological characteristics of patients having atrial flutter with 1:1 atrioventricular conduction.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20080301

Title: Neonatal rat cardiac fibroblasts express three types of voltage-gated K+ channels: regulation of a transient outward current by protein kinase C.

Journal: American journal of physiology. Heart and circulatory physiology 20080201

Title: The challenge of fetal dysrhythmias: echocardiographic diagnosis and clinical management.

Journal: Journal of cardiovascular medicine (Hagerstown, Md.) 20080201

Title: Pharmacogenetics: data, concepts and tools to improve drug discovery and drug treatment.

Journal: European journal of clinical pharmacology 20080201

Title: Flecainide suppresses bidirectional ventricular tachycardia and reverses tachycardia-induced cardiomyopathy in Andersen-Tawil syndrome.

Journal: Journal of cardiovascular electrophysiology 20080101

Title: Criteria for arrhythmogenicity in genetically-modified Langendorff-perfused murine hearts modelling the congenital long QT syndrome type 3 and the Brugada syndrome.

Journal: Pflugers Archiv : European journal of physiology 20080101

Title: Choice of cardiac tissue in vitro plays an important role in assessing the risk of drug-induced cardiac arrhythmias in human: beyond QT prolongation.

Journal: Journal of pharmacological and toxicological methods 20080101

Title: A randomized comparison of amiodarone and class IC antiarrhythmic drugs to treat atrial fibrillation in patients paced for sinus node disease: the Prevention Investigation and Treatment: A Group for Observation and Research on Atrial arrhythmias (PITAGORA) trial.

Journal: American heart journal 20080101

Title: Functional and pharmacological characterization of a Shal-related K+ channel subunit in Zebrafish.

Journal: BMC physiology 20080101

Title: Spontaneous alternans in Brugada ST-segment morphology within minutes.

Journal: Journal of electrocardiology 20080101

Title: Effect of drugs on defibrillation capacity.

Journal: Drugs 20080101

Title: Flecainide: safety and efficacy.

Journal: Cardiology 20080101

Title: Paranoid psychosis and myoclonus: flecainide toxicity in renal failure.

Journal: Cardiology 20080101

Title: Dual ventricular response or 1 : 2 atrioventricular conduction in dual atrioventricular nodal physiology.

Journal: Indian pacing and electrophysiology journal 20080101

Title: Pharmacological therapy in children with atrioventricular reentry: which drug?

Journal: Current pharmaceutical design 20080101

Title: Pharmacological therapy in children with nodal reentry tachycardia: when, how and how long to treat the affected patients.

Journal: Current pharmaceutical design 20080101

Title: [Circumferential pulmonary vein ablation versus antiarrhythmic drug therapy in paroxysmal atrial fibrillation. Results of the APAF trial].

Journal: Kardiologiia 20080101

Title: Epidemiology of arrhythmias in children.

Journal: Indian pacing and electrophysiology journal 20080101

Title: Pediatric electrophysiology in India: a sub-speciality come of age.

Journal: Indian pacing and electrophysiology journal 20080101

Title: Indications for electrophysiology study in children.

Journal: Indian pacing and electrophysiology journal 20080101

Title: Protein C as a surrogate end-point for clinical trials of sepsis.

Journal: Critical care (London, England) 20080101

Title: Laugh syncope as a rare sub-type of the situational syncopes: a case report.

Journal: Journal of medical case reports 20080101

Title: Postmortem increase of flecainide level in cardiac blood.

Journal: Journal of analytical toxicology 20080101

Title: The effect of ranolazine on maintaining sinus rhythm in patients with resistant atrial fibrillation.

Journal: Indian pacing and electrophysiology journal 20080101

Title: Brugada syndrome during physical therapy: a case report.

Journal: Cases journal 20080101

Title: Diagnosis, treatment, observation and outcome of fetal supraventricular tachycardia in a twin pregnancy.

Journal: Fetal diagnosis and therapy 20080101

Title: The prince and the pauper. A tale of anticancer targeted agents.

Journal: Molecular cancer 20080101

Title: Atrial fibrillation (acute onset).

Journal: BMJ clinical evidence 20080101

Title: Long QT syndrome: A therapeutic challenge.

Journal: Annals of pediatric cardiology 20080101

Title: Tachyarrhythmia: Presenting symptom of cardiac tumour.

Journal: Images in paediatric cardiology 20080101

Title: The molecular basis of high-affinity binding of the antiarrhythmic compound vernakalant (RSD1235) to Kv1.5 channels.

Journal: Molecular pharmacology 20071201

Title: ECG findings in fatal flecainide intoxication.

Journal: Heart (British Cardiac Society) 20071201

Title: Flecainide for the treatment of chronic neuropathic pain: a Phase II trial.

Journal: Palliative medicine 20071201

Title: [Clinical case of the month. Atrial flutter with rapid ventricular response (1:1 atrioventricular conduction) caused by flecaïnide].

Journal: Revue medicale de Liege 20071201

Title: Different effects of antiarrhythmic drugs on the rate-dependency of QT interval: a study with amiodarone and flecainide.

Journal: Journal of cardiovascular pharmacology 20071101

Title: Gender-associated differences in pharmacokinetics and anti-arrhythmic effects of flecainide in Japanese patients with supraventricular tachyarrhythmia.

Journal: European journal of clinical pharmacology 20071001

Title: A quantitative analysis of the effect of cycle length on arrhythmogenicity in hypokalaemic Langendorff-perfused murine hearts.

Journal: Pflugers Archiv : European journal of physiology 20070901

Title: Separation of early afterdepolarizations from arrhythmogenic substrate in the isolated perfused hypokalaemic murine heart through modifiers of calcium homeostasis.

Journal: Acta physiologica (Oxford, England) 20070901

Title: Impact of serum flecainide level on control of atrial fibrillation in a case treated with cardiac resynchronization therapy.

Journal: Journal of clinical pharmacy and therapeutics 20070801

Title: Novel mutation in the SCN5A gene associated with arrhythmic storm development during acute myocardial infarction.

Journal: Heart rhythm 20070801

Title: Treatment of chronic atrial fibrillation in the horse with flecainide: personal observation.

Journal: Veterinary research communications 20070801

Title: Reduction of dispersion of repolarization and prolongation of postrepolarization refractoriness explain the antiarrhythmic effects of quinidine in a model of short QT syndrome.

Journal: Journal of cardiovascular electrophysiology 20070601

Title: Quinidine in short QT syndrome: an old drug for a new disease.

Journal: Journal of cardiovascular electrophysiology 20070601

Title: Effects of flecainide and quinidine on arrhythmogenic properties of Scn5a+/- murine hearts modelling the Brugada syndrome.

Journal: The Journal of physiology 20070515

Title: Simultaneous determination of 6 beta-blockers, 3 calcium-channel antagonists, 4 angiotensin-II antagonists and 1 antiarrhythmic drug in post-mortem whole blood by automated solid phase extraction and liquid chromatography mass spectrometry. Method development and robustness testing by experimental design.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070501

Title: Flecainide cardiotoxicity precipitated by electrolyte imbalance. Caution with thiazide diuretics.

Journal: Emergency medicine journal : EMJ 20070501

Title: Further evidence of inherited long QT syndrome gene mutations in antiarrhythmic drug-associated torsades de pointes.

Journal: Heart rhythm 20070501

Title: The pharmacological response of ischemia-related atrial fibrillation in dogs: evidence for substrate-specific efficacy.

Journal: Cardiovascular research 20070401

Title: A common SCN5A variant alters the responsiveness of human sodium channels to class I antiarrhythmic agents.

Journal: Journal of cardiovascular electrophysiology 20070401

Title: The cutaneous analgesic effect of class I antiarrhythmic drugs.

Journal: Anesthesia and analgesia 20070401

Title: Flecainide for recurrent malignant ventricular arrhythmias in two siblings with Andersen-Tawil syndrome.

Journal: Heart rhythm 20070401

Title: Managing cardiovascular collapse in severe flecainide overdose without recourse to extracorporeal therapy.

Journal: Emergency medicine Australasia : EMA 20070401

Title: Some patients with paroxysmal atrial fibrillation should carry flecainide or propafenone to self treat.

Journal: BMJ (Clinical research ed.) 20070324

Title: Simultaneous ST-segment elevation in the right precordial and inferior leads in Brugada syndrome.

Journal: Journal of cardiovascular medicine (Hagerstown, Md.) 20070301

Title: Dose-response effect of flecainide in patients with symptomatic paroxysmal atrial fibrillation and/or flutter monitored with trans-telephonic electrocardiography: a multicenter, placebo-controlled, double-blind trial.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20070301

Title: Brugada-like electrocardiographic pattern and ventricular fibrillation in a patient with primary hyperparathyroidism.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20070301

Title: [Effect of flecainide on longitudinal and transverse conduction velocities in ventricular myocardium. An experimental study].

Journal: Revista espanola de cardiologia 20070301

Title: Haemolysis alters plasma flecainide levels in newborn infants.

Journal: Acta paediatrica (Oslo, Norway : 1992) 20070301

Title: Observations on the safety and effectiveness of dofetilide in patients with paroxysmal atrial fibrillation and normal left ventricular function.

Journal: Journal of cardiovascular pharmacology and therapeutics 20070301

Title: Neuropsychiatric consequences of cardiovascular medications.

Journal: Dialogues in clinical neuroscience 20070301

Title: Kv1.5 is a major component underlying the A-type potassium current in retinal arteriolar smooth muscle.

Journal: American journal of physiology. Heart and circulatory physiology 20070201

Title: Familial clustering of lone atrial fibrillation in patients with saddleback-type ST-segment elevation in right precordial leads.

Journal: European heart journal 20070201

Title: Torsades de pointes complicating atrioventricular block: evidence for a genetic predisposition.

Journal: Heart rhythm 20070201

Title: Anti-arrhythmic effects of I (Na), I (Kr), and combined I (Kr)-I (CaL) blockade in an experimental model of acute stretch-related atrial fibrillation.

Journal: Cardiovascular drugs and therapy 20070201

Title: Torsade-de-pointes in a patient under flecainide treatment, an unusual case of proarrhythmicity.

Journal: International journal of cardiology 20070108

Title: In silico assessment of Y1795C and Y1795H SCN5A mutations: implication for inherited arrhythmogenic syndromes.

Journal: American journal of physiology. Heart and circulatory physiology 20070101

Title: Effects of flecainide and quinidine on arrhythmogenic properties of Scn5a+/Delta murine hearts modelling long QT syndrome 3.

Journal: The Journal of physiology 20070101

Title: Do your patients suffer from excessive yawning?

Journal: Acta psychiatrica Scandinavica 20070101

Title: Clinical review: aggressive management and extracorporeal support for drug-induced cardiotoxicity.

Journal: Critical care (London, England) 20070101

Title: Action potential experiments complete hERG assay and QT-interval measurements in cardiac preclinical studies.

Journal: Journal of pharmacological and toxicological methods 20070101

Title: Steroids in late ARDS?

Journal: Critical care (London, England) 20070101

Title: Simultaneous separation of 14 antiarrhythmic drugs and determination of mexiletine and flecainide by capillary zone electrophoresis.

Journal: Journal of AOAC International 20070101

Title: [Brugada syndrome and work place: two case report].

Journal: Giornale italiano di medicina del lavoro ed ergonomia 20070101

Title: A novel and lethal de novo LQT-3 mutation in a newborn with distinct molecular pharmacology and therapeutic response.

Journal: PloS one 20070101

Title: [New strategies in the treatment of atrial fibrillation].

Journal: Anales de la Real Academia Nacional de Medicina 20070101

Title: Planning a clinical research study.

Journal: Indian journal of orthopaedics 20070101

Title: Overlap syndrome of cardiac sodium channel disease in mice carrying the equivalent mutation of human SCN5A-1795insD.

Journal: Circulation 20061212

Title: A randomized trial of circumferential pulmonary vein ablation versus antiarrhythmic drug therapy in paroxysmal atrial fibrillation: the APAF Study.

Journal: Journal of the American College of Cardiology 20061205

Title: Long-term protection of central axons with phenytoin in monophasic and chronic-relapsing EAE.

Journal: Brain : a journal of neurology 20061201

Title: [Be careful in using flecainide by hemodialyzed patients].

Journal: Nephrologie & therapeutique 20061201

Title: Auto-intoxication with flecainide and quinapril: ECG-changes, symptoms and treatment.

Journal: Acta cardiologica 20061201

Title: Use of telemedicine in the diagnosis of paroxysmal atrial fibrillation and to monitor the effect of antiarrhythmic drug therapy.

Journal: Herzschrittmachertherapie & Elektrophysiologie 20061201

Title: Effect of amiodarone on the serum concentration/dose ratio of metoprolol in patients with cardiac arrhythmia.

Journal: Drug metabolism and pharmacokinetics 20061201

Title: Altered Na+ channels promote pause-induced spontaneous diastolic activity in long QT syndrome type 3 myocytes.

Journal: Circulation research 20061124

Title: [What is your diagnosis? Brugada syndrome].

Journal: Praxis 20061122

Title: Properties of a time-dependent potassium current in pig atrium: evidence for a role of kv1.5 in repolarization.

Journal: The Journal of pharmacology and experimental therapeutics 20061101

Title: Effect of CYP2D6 genotype on flecainide pharmacokinetics in Japanese patients with supraventricular tachyarrhythmia.

Journal: European journal of clinical pharmacology 20061101

Title: Transthoracic tissue Doppler imaging of the atria: a novel method to determine the atrial fibrillation cycle length.

Journal: Journal of cardiovascular electrophysiology 20061101

Title: Pharmacological and molecular evidence for the involvement of Kv4.3 in ultra-fast activating K+ currents in murine portal vein myocytes.

Journal: British journal of pharmacology 20061101

Title: Negative flecainide test in Brugada syndrome patients with previous positive response.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20061001

Title: Determinants of sudden cardiac death in patients with persistent atrial fibrillation in the rate control versus electrical cardioversion (RACE) study.

Journal: The American journal of cardiology 20061001

Title: [Atrioventricular nodal reentry tachycardia in children].

Journal: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20060921

Title: Diabetes mellitus reduces the antiarrhythmic effect of ion channel blockers.

Journal: Anesthesia and analgesia 20060901

Title: Atrial fibrillation: choosing an antiarrhythmic drug.

Journal: Current cardiology reports 20060901

Title: Fetal and maternal magnetocardiography during flecainide therapy for supraventricular tachycardia.

Journal: Obstetrics and gynecology 20060901

Title: Diagnostic value of flecainide testing in unmasking SCN5A-related Brugada syndrome.

Journal: Journal of cardiovascular electrophysiology 20060801

Title: Flecainide sensitivity of a Na channel long QT mutation shows an open-channel blocking mechanism for use-dependent block.

Journal: American journal of physiology. Heart and circulatory physiology 20060701

Title: Flecainide treatment of fetal tachycardia and hydrops fetalis in a twin pregnancy.

Journal: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 20060701

Title: [Permanent His-bundle pacing in patients with infra-Hisian atrioventricular block].

Journal: Revista espanola de cardiologia 20060601

Title: [Flecainide acetate utilisation review among general practitioners and hospital or office-based cardiologists in France. Obepine: observational study of flecainide].

Journal: Annales de cardiologie et d'angeiologie 20060601

Title: Serial cardioversion by class IC Drugs during 4 months of persistent atrial fibrillation in the goat.

Journal: Journal of cardiovascular electrophysiology 20060601

Title: Too little, too late: chasing atrial fibrillation with sodium channel antagonists.

Journal: Journal of cardiovascular electrophysiology 20060601

Title: [Life-threatening ventricular tachycardia during flecainide treatment for symptomatic atrial fibrillation in a patient with a structural cardiac disorder].

Journal: Nederlands tijdschrift voor geneeskunde 20060506

Title: [Intravenous flecainide administration for conversion of paroxysmal atrial fibrillation in the emergency room].

Journal: Harefuah 20060501

Title: Verapamil-sensitive ventricular tachycardia in an infant.

Journal: Congenital heart disease 20060501

Title: [Drug treatment of atrial fibrillation].

Journal: MMW Fortschritte der Medizin 20060413

Title: Tolerability and safety of fluvoxamine and other antidepressants.

Journal: International journal of clinical practice 20060401

Title: Brugada-like electrocardiogram pattern: how to stratify the risk for sudden cardiac death. Is sports activity contraindicated?

Journal: Journal of cardiovascular medicine (Hagerstown, Md.) 20060401

Title: Combined use of 1C and III agents for highly symptomatic, refractory atrial fibrillation.

Journal: Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing 20060401

Title: Actions of flecainide on susceptibility to phase-2 ventricular arrhythmias during infarct evolution in rat isolated perfused hearts.

Journal: British journal of pharmacology 20060301

Title: A case of acute ventricular capture threshold rise associated with flecainide acetate.

Journal: Yonsei medical journal 20060227

Title: Class Ic antiarrhythmics block human skeletal muscle Na channel during myotonia-like stimulation.

Journal: European journal of pharmacology 20060217

Title: Different glibenclamide-sensitivity of ATP-sensitive K+ currents using different patch-clamp recording methods.

Journal: European journal of pharmacology 20060215

Title: Brugada-type ECG association with unexpected sick sinus syndrome.

Journal: Pacing and clinical electrophysiology : PACE 20060201

Title: [Flecainide controlled-release for prevention of atrial fibrillation relapse].

Journal: Archives des maladies du coeur et des vaisseaux 20060201

Title: Medications used to manage supraventricular tachycardia in the infant a North American survey.

Journal: Pediatric cardiology 20060101

Title: An avoidable antiarrhythmic side effect.

Journal: British journal of hospital medicine (London, England : 2005) 20060101

Title: High-resolution analysis of the surface P wave as a measure of atrial electrophysiological substrate.

Journal: Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc 20060101

Title: Successful conversion of equine atrial fibrillation using oral flecainide.

Journal: Journal of veterinary internal medicine 20060101

Title: Cardiac effects of ST-6, a novel cyclohexane dicarboximide derivative.

Journal: Cardiovascular drug reviews 20060101

Title: Short- and long-term experience in pulmonary vein segmental ostial ablation for paroxysmal atrial fibrillation.

Journal: Indian pacing and electrophysiology journal 20060101

Title: Andersen-Tawil syndrome.

Journal: Indian pacing and electrophysiology journal 20060101

Title: Atrial fibrillation and pacing algorithms.

Journal: Indian pacing and electrophysiology journal 20060101

Title: Brugada syndrome.

Journal: Orphanet journal of rare diseases 20060101

Title: Brugada syndrome unmasked by sodium channel blockade.

Journal: Indian heart journal 20060101

Title: Primary prevention of fatal ventricular arrhythmias with implantable cardioverter-defibrillator therapy--an analysis of implications based on MADIT II criteria.

Journal: McGill journal of medicine : MJM : an international forum for the advancement of medical sciences by students 20060101

Title: Oxidative mediated lipid peroxidation recapitulates proarrhythmic effects on cardiac sodium channels.

Journal: Circulation research 20051209

Title: Atrial fibrillation (recent onset).

Journal: Clinical evidence 20051201

Title: [Atrial flutter and fibrillation].

Journal: Praxis 20051109

Title: Analysis of current management of atrial fibrillation in the acute setting: GEFAUR-1 study.

Journal: Annals of emergency medicine 20051101

Title: Targeted pharmacological reversal of electrical remodeling after cardioversion--rationale and design of the Flecainide Short-Long (Flec-SL) trial.

Journal: American heart journal 20051101

Title: [Electrocardiographic findings typical of Brugada syndrome unmasked by cocaine consumption].

Journal: Revista espanola de cardiologia 20051101

Title: Warming and response to contractile agents in calf cardiac vein: role of the Ca2+, KCa2+, and Na+ ion channel blockers.

Journal: Methods and findings in experimental and clinical pharmacology 20051101

Title: Systemic administration of local anesthetic agents to relieve neuropathic pain.

Journal: The Cochrane database of systematic reviews 20051019

Title: Pediatric radiofrequency catheter ablation: results of initial 100 consecutive cases including congenital heart anomalies.

Journal: Journal of Korean medical science 20051001

Title: Short QT syndrome. Genotype-phenotype correlations.

Journal: Journal of electrocardiology 20051001

Title: Safety and efficacy of flecainide in subjects with Long QT-3 syndrome (DeltaKPQ mutation): a randomized, double-blind, placebo-controlled clinical trial.

Journal: Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc 20051001

Title: Low-energy radiofrequency catheter ablation as therapy for supraventricular tachycardia in a premature neonate.

Journal: European journal of pediatrics 20050901

Title: Molecular and pharmacological characteristics of transient voltage-dependent K+ currents in cultured human pulmonary arterial smooth muscle cells.

Journal: British journal of pharmacology 20050901

Title: Flecainide-induced neuropathy.

Journal: The Annals of pharmacotherapy 20050901

Title: Clinical and electrophysiologic profile of Brugada syndrome in Iranian patients.

Journal: Asian cardiovascular & thoracic annals 20050901

Title: A novel nonsense mutation in the SCN5A gene leads to Brugada syndrome and a silent gene mutation carrier state.

Journal: The Canadian journal of cardiology 20050901

Title: [Flecainide overdose: report of a case].

Journal: Anales de medicina interna (Madrid, Spain : 1984) 20050901

Title: A cautionary tale: the risks of flecainide treatment for myotonic dystrophy.

Journal: Journal of clinical neuromuscular disease 20050901

Title: Short QT syndrome.

Journal: Cardiovascular research 20050815

Title: A single residue in the S6 transmembrane domain governs the differential flecainide sensitivity of voltage-gated potassium channels.

Journal: Molecular pharmacology 20050801

Title: Successful use of an intravenous infusion of flecainide and amiodarone for a refractory combination of postoperative junctional and ectopic tachycardias.

Journal: Cardiology in the young 20050801

Title: Successful treatment of tachycardia-induced cardiomyopathy with LVAD in a 12-year-old boy.

Journal: The Annals of thoracic surgery 20050801

Title: Pharmacologic control of ventricular rate: American College of Chest Physicians guidelines for the prevention and management of postoperative atrial fibrillation after cardiac surgery.

Journal: Chest 20050801

Title: Consequences of atrial electrical remodeling for the anti-arrhythmic action of class IC and class III drugs.

Journal: Cardiovascular research 20050701

Title: Diphenhydramine overdose and Brugada sign.

Journal: Pacing and clinical electrophysiology : PACE 20050701

Title: Predictors of atrial antitachycardia pacing efficacy in patients affected by brady-tachy form of sick sinus syndrome and implanted with a DDDRP device.

Journal: Journal of cardiovascular electrophysiology 20050701

Title: Atrial fibrillation recurrence after drug-induced typical atrial flutter ablation.

Journal: Italian heart journal : official journal of the Italian Federation of Cardiology 20050701

Title: Narrow QRS complex tachycardia with a high-frequency potential recorded near the His bundle: what is the mechanism?

Journal: Heart rhythm 20050601

Title: [Pharmacogenetic study of the response to flecainide and propafenone in patients with atrial fibrillation].

Journal: Revista espanola de cardiologia 20050601

Title: Class I antiarrhythmics inhibit Na+ absorption and Cl- secretion in rabbit descending colon epithelium.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20050601

Title: [Outpatient treatment of recurrent atrial fibrillation with the 'pill-in-the-pocket' approach: practical aspects].

Journal: Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology 20050601

Title: Expert Canadian consensus suggestions on the rational, clinical use of ziprasidone in the treatment of schizophrenia and related psychotic disorders.

Journal: Neuropsychiatric disease and treatment 20050601

Title: The effects of putative K+ channel blockers on volume regulation of murine spermatozoa.

Journal: Biology of reproduction 20050501

Title: Pharmacologic prophylaxis for postoperative atrial tachyarrhythmia in general thoracic surgery: evidence from randomized clinical trials.

Journal: The Journal of thoracic and cardiovascular surgery 20050501

Title: [Reason for worry: syncope in the morning].

Journal: MMW Fortschritte der Medizin 20050421

Title: [Acute treatment of stable hemodynamically tolerable ventricular tachycardia].

Journal: Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS 20050401

Title: Pilot study: Noninvasive monitoring of oral flecainide's effects on atrial electrophysiology during persistent human atrial fibrillation using the surface electrocardiogram.

Journal: Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc 20050401

Title: The 'pill-in-the-pocket' approach to atrial fibrillation.

Journal: The New England journal of medicine 20050317

Title: Electrophysiological effects of flecainide and sotalol in the human atrium during persistent atrial fibrillation.

Journal: Basic research in cardiology 20050301

Title: Long-term follow-up after radiofrequency catheter ablation of atrial fibrillation: role of the acute procedure outcome and of the clinical presentation.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20050301

Title: [Prevalence of Brugada syndrome among 35,309 inhabitants of Lorraine screened at a preventive medicine centre].

Journal: Archives des maladies du coeur et des vaisseaux 20050301

Title: Does flecainide regain its antiarrhythmic activity after electrical cardioversion of persistent atrial fibrillation?

Journal: Heart rhythm 20050301

Title: Intravenous drug challenge using flecainide and ajmaline in patients with Brugada syndrome.

Journal: Heart rhythm 20050301

Title: Are all sodium channel blockers created equal? Clinical-basic correlations based on observations in Brugada syndrome.

Journal: Heart rhythm 20050301

Title: Antiarrhythmic drugs in patients with recurrent atrial fibrillation: where are we?

Journal: Italian heart journal : official journal of the Italian Federation of Cardiology 20050301

Title: Can recent-onset atrial fibrillation be safely and successfully treated with self-administered antiarrhythmic drugs?

Journal: Nature clinical practice. Cardiovascular medicine 20050301

Title: Time-frequency analysis of the surface electrocardiogram for monitoring antiarrhythmic drug effects in atrial fibrillation.

Journal: The American journal of cardiology 20050215

Title: Appropriate dosing of antiarrhythmic drugs in Japan requires therapeutic drug monitoring.

Journal: Journal of clinical pharmacy and therapeutics 20050201

Title: Spontaneous T wave alternans in a patient with Brugada syndrome--responses to intravenous administration of class I antiarrhythmic drug, glucose tolerance test, and atrial pacing.

Journal: Journal of cardiovascular electrophysiology 20050201

Title: [Combination therapy for fetal supraventricular tachycardia with flecainide and digoxin].

Journal: Zeitschrift fur Geburtshilfe und Neonatologie 20050201

Title: Brugada syndrome--an update.

Journal: Chang Gung medical journal 20050201

Title: Axonal protection in experimental autoimmune neuritis by the sodium channel blocking agent flecainide.

Journal: Brain : a journal of neurology 20050101

Title: Recurrent cardiac events in patients with idiopathic ventricular fibrillation, excluding patients with the Brugada syndrome.

Journal: BMC medicine 20050101

Title: Assessment of serum flecainide trough levels in patients with tachyarrhythmia.

Journal: The Journal of pharmacy and pharmacology 20050101

Title: Efficacy of an implantable cardioverter-defibrillator in a neonate with LQT3 associated arrhythmias.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20050101

Title: Long-term results of hybrid therapy in patients with atrial fibrillation who develop atrial flutter during flecainide infusion.

Journal: Pacing and clinical electrophysiology : PACE 20050101

Title: [Diagnosis and antenatal treatment of fetal arrhythmias].

Journal: Therapeutische Umschau. Revue therapeutique 20050101

Title: [Indications for automatic implantable defibrillators in patients with the Brugada syndrome].

Journal: Annales de cardiologie et d'angeiologie 20050101

Title: [Atrial fibrillation: choice of the method of pharmacological cardioversion].

Journal: Kardiologiia 20050101

Title: Chiropractic as spine care: a model for the profession.

Journal: Chiropractic & osteopathy 20050101

Title: [Fetal supraventricular tachyarrhythmias refractory to initial therapy].

Journal: Medicina 20050101

Title: Safe and effective pharmacologic management of arrhythmias.

Journal: Texas Heart Institute journal 20050101

Title: Transplacental pharmacokinetics of flecainide in the gravid baboon and fetus.

Journal: Pediatric cardiology 20050101

Title: Flecainide overdose--support using an intra-aortic balloon pump.

Journal: BMC emergency medicine 20050101

Title: Automatic mode switching in atrial fibrillation.

Journal: Indian pacing and electrophysiology journal 20050101

Title: Non-linear heart rate variability and risk stratification in cardiovascular disease.

Journal: Indian pacing and electrophysiology journal 20050101

Title: Atrial fibrillation and its determinants after radiofrequency ablation of chronic common atrial flutter.

Journal: Indian pacing and electrophysiology journal 20050101

Title: Rate-control or rhythm-control: where do we stand?

Journal: Indian pacing and electrophysiology journal 20050101

Title: Electrical storms in Brugada syndrome: review of pharmacologic and ablative therapeutic options.

Journal: Indian pacing and electrophysiology journal 20050101

Title: Bundle branch reentrant ventricular tachycardia.

Journal: Indian pacing and electrophysiology journal 20050101

Title: Ventricular tachycardia in the absence of structural heart disease.

Journal: Indian pacing and electrophysiology journal 20050101

Title: Acute lung affection in an endurance-trained man under amiodarone medication.

Journal: German medical science : GMS e-journal 20050101

Title: Outpatient treatment of recent-onset atrial fibrillation with the 'pill-in-the-pocket' approach.

Journal: The New England journal of medicine 20041202

Title: Flecainide challenge test for the diagnosis of Brugada syndrome.

Journal: Postgraduate medical journal 20041201

Title: Synergistic action of atrial dilation and sodium channel blockade on conduction in rabbit atria.

Journal: Journal of cardiovascular electrophysiology 20041201

Title: Absorption kinetics and pharmacodynamics of two oral dosage forms of flecainide in patients with an episode of paroxysmal atrial fibrillation.

Journal: European journal of clinical pharmacology 20041201

Title: Falls in three patients due to timolol eye drops, tolterodine, and flecainide.

Journal: The journals of gerontology. Series A, Biological sciences and medical sciences 20041201

Title: Wide QRS complexes during atrial fibrillation: what is the mechanism?

Journal: Heart rhythm 20041201

Title: Flecainide and propafenone induced ST-segment elevation in patients with atrial fibrillation: clue to specificity of Brugada-type electrocardiographic changes.

Journal: The American journal of cardiology 20041101

Title: Different clinical courses and predictors of atrial fibrillation occurrence after transisthmic ablation in patients with preablation lone atrial flutter, coexistent atrial fibrillation, and drug induced atrial flutter.

Journal: Pacing and clinical electrophysiology : PACE 20041101

Title: Use of intravenous flecainide in horses with naturally-occurring atrial fibrillation.

Journal: Equine veterinary journal 20041101

Title: State-dependent trapping of flecainide in the cardiac sodium channel.

Journal: The Journal of physiology 20041001

Title: Acute ventricular rate control in atrial fibrillation and atrial flutter.

Journal: International journal of cardiology 20041001

Title: Fetal supraventricular tachycardia diagnosed and treated at twenty-four weeks of gestation and after birth: a case report.

Journal: Italian heart journal : official journal of the Italian Federation of Cardiology 20041001

Title: Previous therapy with amiodarone increases the recurrence rate in successfully ablated patients with isthmus-dependent atrial flutter.

Journal: Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 20041001

Title: Efficacy of quinidine in high-risk patients with Brugada syndrome.

Journal: Circulation 20040928

Title: Limitations to antiarrhythmic drug use in patients with atrial fibrillation.

Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20040928

Title: Simultaneous determination of serum flecainide and its metabolites by using high performance liquid chromatography.

Journal: Journal of pharmaceutical and biomedical analysis 20040903

Title: Dynamic remodeling of K+ and Ca2+ currents in cells that survived in the epicardial border zone of canine healed infarcted heart.

Journal: American journal of physiology. Heart and circulatory physiology 20040901

Title: Surface atrial frequency analysis in patients with atrial fibrillation: a tool for evaluating the effects of intervention.

Journal: Journal of cardiovascular electrophysiology 20040901

Title: Brugada electrocardiographic pattern elicited by inadvertent flecainide overdose.

Journal: Pacing and clinical electrophysiology : PACE 20040901

Title: [Can myocardial Na+ channel gene mutation be a prognostic factor for sudden death in asymptomatic Brugada syndrome?].

Journal: [Hokkaido igaku zasshi] The Hokkaido journal of medical science 20040901

Title: Imaging dopamine neurotransmission in Parkinson's disease: biomarker versus surrogate end point.

Journal: Dialogues in clinical neuroscience 20040901

Title: Use of ibutilide in cardioversion of patients with atrial fibrillation or atrial flutter treated with class IC agents.

Journal: Journal of the American College of Cardiology 20040818

Title: The effects of class Ic antiarrhythmics on tetrodotoxin-resistant Na+ currents in rat sensory neurons.

Journal: Anesthesia and analgesia 20040801

Title: Pharmacological cardioversion of recent onset atrial fibrillation.

Journal: European heart journal 20040801

Title: Flecainide versus ibutilide for immediate cardioversion of atrial fibrillation of recent onset.

Journal: European heart journal 20040801

Title: Atrial fibrillation in rats induced by rapid transesophageal atrial pacing during brief episodes of asphyxia: a new in vivo model.

Journal: Journal of cardiovascular pharmacology 20040701

Title: Atrial-selective antiarrhythmic actions of novel Ikur vs. Ikr, Iks, and IKAch class Ic drugs and beta blockers in pigs.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20040701

Title: Differentiation of the electrophysiological effects on the atrial myocardium between the pure Na channel blocker, pilsicainide, and flecainide.

Journal: Cardiovascular drugs and therapy 20040701

Title: Symptomatic arrhythmia recurrence as an outcome in clinical trials of antiarrhythmic drug therapy.

Journal: Heart rhythm 20040701

Title: Role of sodium and calcium channel block in unmasking the Brugada syndrome.

Journal: Heart rhythm 20040701

Title: Cardioversion threshold, IRAF and beyond.

Journal: European heart journal 20040601

Title: Atrial fibrillation (acute).

Journal: Clinical evidence 20040601

Title: Axonal protection using flecainide in experimental autoimmune encephalomyelitis.

Journal: Annals of neurology 20040501

Title: Novel therapeutics for treatment of long-QT syndrome and torsade de pointes.

Journal: International journal of cardiology 20040501

Title: Short QT syndrome: pharmacological treatment.

Journal: Journal of the American College of Cardiology 20040421

Title: Oral antiarrhythmic drugs in converting recent onset atrial fibrillation.

Journal: Pharmacy world & science : PWS 20040401

Title: Atrial fibrillation: rate control often better than rhythm control.

Journal: Prescrire international 20040401

Title: Delay in right ventricular activation contributes to Brugada syndrome.

Journal: Circulation 20040316

Title: Characterization of a fast transient outward current in neocortical neurons from epilepsy patients.

Journal: Journal of neuroscience research 20040315

Title: Best evidence topic report. Amiodarone or flecainide for cardioversion in acute onset atrial fibrillation.

Journal: Emergency medicine journal : EMJ 20040301

Title: Effects of pretreatment with intravenous flecainide on efficacy of external cardioversion of persistent atrial fibrillation.

Journal: Pacing and clinical electrophysiology : PACE 20040301

Title: Phenotypic differences in transient outward K+ current of human and canine ventricular myocytes: insights into molecular composition of ventricular Ito.

Journal: American journal of physiology. Heart and circulatory physiology 20040201

Title: Antiarrhythmic drug therapy of atrial fibrillation.

Journal: Cardiology clinics 20040201

Title: Different flecainide sensitivity of hNav1.4 channels and myotonic mutants explained by state-dependent block.

Journal: The Journal of physiology 20040115

Title: Neonatal intractable atrial flutter successfully treated with intravenous flecainide.

Journal: Pediatric cardiology 20040101

Title: Effects of class I antiarrhythmic drugs on the digitalis-induced triggered activity arrhythmia model: a rationale for the short-term use of class I drugs against triggered arrhythmias.

Journal: Heart and vessels 20040101

Title: Incidence and management of early recurrent atrial fibrillation (ERAF) after transthoracic electrical cardioversion.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20040101

Title: Drug-drug interactions between antiarrhythmic drugs in chick embryos.

Journal: Biological & pharmaceutical bulletin 20040101

Title: Theoretical possibilities for the development of novel antiarrhythmic drugs.

Journal: Current medicinal chemistry 20040101

Title: Pro/con clinical debate: steroids are a key component in the treatment of SARS. Pro: Yes, steroids are a key component of the treatment regimen for SARS.

Journal: Critical care (London, England) 20040101

Title: Arrhythmia-provoking factors and symptoms at the onset of paroxysmal atrial fibrillation: a study based on interviews with 100 patients seeking hospital assistance.

Journal: BMC cardiovascular disorders 20040101

Title: Clinical review: clinical management of atrial fibrillation - rate control versus rhythm control.

Journal: Critical care (London, England) 20040101

Title: Assessment of the dynamics of atrial signals and local atrial period series during atrial fibrillation: effects of isoproterenol administration.

Journal: Biomedical engineering online 20040101

Title: Inactivation-deficient human skeletal muscle Na+ channels (hNav1.4-L443C/A444W) in stably transfected HEK-293 cells.

Journal: Receptors & channels 20040101

Title: Pharmacological cardioversion of atrial fibrillation: current management and treatment options.

Journal: Drugs 20040101

Title: Effects of flecainide on atrial and ventricular refractoriness in rabbits in vitro and in vivo.

Journal: Proceedings of the Western Pharmacology Society 20040101

Title: Fetal tachyarrhythmia - part II: treatment.

Journal: Indian pacing and electrophysiology journal 20040101

Title: Fetal tachyarrhythmia--part I: Diagnosis.

Journal: Indian pacing and electrophysiology journal 20040101

Title: Frequency analysis of atrial fibrillation from the surface electrocardiogram.

Journal: Indian pacing and electrophysiology journal 20040101

Title: Management of atrial fibrillation: review of the evidence for the role of pharmacologic therapy, electrical cardioversion, and echocardiography.

Journal: Annals of internal medicine 20031216

Title: Ropivacaine combined with various anti-arrhythmic drugs results in mild alterations in myocardial contractility in pigs.

Journal: Canadian journal of anaesthesia = Journal canadien d'anesthesie 20031201

Title: Atrial fibrillation (acute).

Journal: Clinical evidence 20031201

Title: QT-interval prolongation in right precordial leads: an additional electrocardiographic hallmark of Brugada syndrome.

Journal: Journal of the American College of Cardiology 20031105

Title: Flecainide induced ventricular fibrillation in a neonate.

Journal: Heart (British Cardiac Society) 20031001

Title: Arrhythmias in the intensive care patient.

Journal: Current opinion in critical care 20031001

Title: Frequency measures obtained from the surface electrocardiogram in atrial fibrillation research and clinical decision-making.

Journal: Journal of cardiovascular electrophysiology 20031001

Title: Neonatal flecainide toxicity following supraventricular tachycardia treatment.

Journal: The Annals of pharmacotherapy 20030901

Title: Flecainide induced ventricular tachycardia (torsades de pointes).

Journal: Pacing and clinical electrophysiology : PACE 20030901

Title: Short QT Syndrome: a familial cause of sudden death.

Journal: Circulation 20030826

Title: Atrial fibrillation with a very rapid ventricular response as the first clinical arrhythmia in a 76-year-old man.

Journal: Pacing and clinical electrophysiology : PACE 20030801

Title: VErapamil plus antiarrhythmic drugs reduce atrial fibrillation recurrences after an electrical cardioversion (VEPARAF Study).

Journal: European heart journal 20030801

Title: Risk factors for recurrence of atrial fibrillation in patients undergoing hybrid therapy for antiarrhythmic drug-induced atrial flutter.

Journal: European heart journal 20030701

Title: Intravenous flecainide for the treatment of junctional ectopic tachycardia after surgery for congenital heart disease.

Journal: The Annals of thoracic surgery 20030701

Title: Electrocardiographic pattern of Brugada syndrome disclosed by a febrile illness: clinical and therapeutic implications.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20030701

Title: Class I or class III agents for atrial fibrillation: are asking the right question?

Journal: Pacing and clinical electrophysiology : PACE 20030701

Title: [Drug therapy of atrial fibrillation].

Journal: Orvosi hetilap 20030615

Title: Liquid chromatographic determination of unbound flecainide in therapeutic drug monitoring.

Journal: Journal of pharmaceutical and biomedical analysis 20030601

Title: Amiodarone for pharmacological cardioversion of recent-onset atrial fibrillation.

Journal: International journal of cardiology 20030601

Title: [Pharmacological interaction between flecainide and benziodarone].

Journal: Revista espanola de cardiologia 20030601

Title: [Results of prenatal management of fetuses with supraventricular tachycardia. A series of 66 cases].

Journal: Journal de gynecologie, obstetrique et biologie de la reproduction 20030601

Title: Extracellular acidosis modulates drug block of Kv4.3 currents by flecainide and quinidine.

Journal: Journal of cardiovascular electrophysiology 20030601

Title: Rhythm versus rate control after ablation and pacing for paroxysmal atrial fibrillation: clinical implications of the PAF 2 trial.

Journal: Cardiac electrophysiology review 20030601

Title: Pharmacodynamic equivalence of two flecainide acetate formulations in patients with paroxysmal atrial fibrillation by QRS analysis of ambulatory electrocardiogram.

Journal: Journal of cardiovascular pharmacology 20030501

Title: Effects of flecainide on the electrophysiological properties of atrial vulnerability in humans.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20030501

Title: Tachycardiac storm in infant with WPW syndrome: 'rescue' radiofrequency ablation.

Journal: Indian pediatrics 20030501

Title: Refractoriness and conduction interaction during modulation of non-ischemic ventricular fibrillation by flecainide.

Journal: Cardiovascular drugs and therapy 20030501

Title: Neonatal ECG changes caused by supratherapeutic flecainide following treatment for fetal supraventricular tachycardia.

Journal: Heart (British Cardiac Society) 20030401

Title: Effects of flecainide and quinidine on Kv4.2 currents: voltage dependence and role of S6 valines.

Journal: British journal of pharmacology 20030401

Title: A newly characterized SCN5A mutation underlying Brugada syndrome unmasked by hyperthermia.

Journal: Journal of cardiovascular electrophysiology 20030401

Title: Old and new antiarrhythmic drugs for converting and maintaining sinus rhythm in atrial fibrillation: comparative efficacy and results of trials.

Journal: The American journal of cardiology 20030320

Title: Pharmacologic and nonpharmacologic options to maintain sinus rhythm: guideline-based and new approaches.

Journal: The American journal of cardiology 20030320

Title: Effects of antiarrhythmic drugs on fibrillation in the remodeled atrium: insights into the mechanism of the superior efficacy of amiodarone.

Journal: Circulation 20030318

Title: Therapeutic monitoring of class I antiarrhythmic agents using high-resolution electrocardiography instead of blood samples.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20030301

Title: Fetal supraventricular tachycardia diagnosed and treated at 13 weeks of gestation: a case report.

Journal: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 20030301

Title: Digoxin remains useful in the management of chronic heart failure.

Journal: The Medical clinics of North America 20030301

Title: Detection of proarrhythmia in the female rabbit heart: blinded validation.

Journal: Journal of cardiovascular electrophysiology 20030301

Title: Persistent junctional reciprocating tachycardia in the fetus.

Journal: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 20030301

Title: Blockers of sodium and calcium entry protect axons from nitric oxide-mediated degeneration.

Journal: Annals of neurology 20030201

Title: Oral loading single dose flecainide for pharmacological cardioversion of recent-onset atrial fibrillation.

Journal: International journal of cardiology 20030201

Title: Fetal supraventricular tachycardia: a role for amiodarone as second-line therapy?

Journal: Prenatal diagnosis 20030201

Title: Novel brugada SCN5A mutation leading to ST segment elevation in the inferior or the right precordial leads.

Journal: Journal of cardiovascular electrophysiology 20030201

Title: Safety of a controlled-release flecainide acetate formulation in the prevention of paroxysmal atrial fibrillation in outpatients.

Journal: Annales de cardiologie et d'angeiologie 20030201

Title: [Infusion of flecainide in a patient with atrial fibrillation and latent Brugada's syndrome has determined modifications of the electrocardiogram similar to those of a septal myocardial infarct].

Journal: Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology 20030201

Title: Influence of quinidine and flecainide on autonomic nervous activity in thoroughbred horses.

Journal: The Veterinary record 20030125

Title: Evaluation of the effect of bepridil on paroxysmal atrial fibrillation: relationship between efficacy and the f-f interval in surface ECG recordings.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20030101

Title: [Normal conventional electrocardiogram with negative pharmacological stress test does not rule out Brugada syndrome].

Journal: Revista espanola de cardiologia 20030101

Title: Successful treatment of supraventricular tachycardia exhibiting hydrops fetalis with flecainide acetate. A case report.

Journal: Fetal diagnosis and therapy 20030101

Title: Analysis of flecainide and two metabolites in biological specimens by HPLC: application to a fatal intoxication.

Journal: Journal of analytical toxicology 20030101

Title: Lopinavir/ritonavir: a review of its use in the management of HIV infection.

Journal: Drugs 20030101

Title: Bepridil prevents paroxysmal atrial fibrillation by a class III antiarrhythmic drug effect.

Journal: Pacing and clinical electrophysiology : PACE 20030101

Title: Flecainide test in Brugada syndrome: a reproducible but risky tool.

Journal: Pacing and clinical electrophysiology : PACE 20030101

Title: [Postoperative atrial fibrillation].

Journal: Duodecim; laaketieteellinen aikakauskirja 20030101

Title: Mutations in cardiac sodium channels: clinical implications.

Journal: American journal of pharmacogenomics : genomics-related research in drug development and clinical practice 20030101

Title: Low-dose flecainide infusion followed by oral pilsicainide is highly effective and safe for paroxysmal atrial fibrillation.

Journal: Cardiovascular drugs and therapy 20030101

Title: What caused this wide-complex tachycardia?

Journal: Progress in cardiovascular nursing 20030101

Title: [Fetal arrhythmia--own experience].

Journal: Medycyna wieku rozwojowego 20030101

Title: Brugada-like electrocardiographic pattern.

Journal: Indian pacing and electrophysiology journal 20030101

Title: Congenital junctional ectopic tachycardia: presentation and outcome.

Journal: Indian pacing and electrophysiology journal 20030101

Title: Role of atrial fibrillation threshold evaluation on guiding treatment.

Journal: Indian pacing and electrophysiology journal 20030101

Title: Brugada disease: chronology of discovery and paternity. Preliminary observations and historical aspects.

Journal: Indian pacing and electrophysiology journal 20030101

Title: Preventing sudden death and the use of prophylactic implanted defibrillators.

Journal: Indian pacing and electrophysiology journal 20030101

Title: Atrial remodeling: evolving concepts.

Journal: Indian pacing and electrophysiology journal 20030101

Title: Importance of left atrial diameter and atrial fibrillatory frequency for conversion of persistent atrial fibrillation with oral flecainide.

Journal: The American journal of cardiology 20021101

Title: Transient Brugada-type electrocardiographic abnormalities in renal failure reversed by dialysis.

Journal: Resuscitation 20021101

Title: What is the minimal pacing rate that prevents torsades de pointes? Insights from patients with permanent pacemakers.

Journal: Pacing and clinical electrophysiology : PACE 20021101

Title: Contribution of Kv4 channels toward the A-type potassium current in murine colonic myocytes.

Journal: The Journal of physiology 20021015

Title: Characterization of the A-type potassium current in murine gastric antrum.

Journal: The Journal of physiology 20021015

Title: Atrial fibrillation threshold predicted long-term efficacy of pharmacological treatment of patients without structural heart disease.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20021001

Title: Maintaining stability of sinus rhythm in atrial fibrillation: antiarrhythmic drugs versus ablation.

Journal: Current cardiology reports 20020901

Title: A-type potassium currents active at subthreshold potentials in mouse cerebellar Purkinje cells.

Journal: The Journal of physiology 20020901

Title: High performance liquid chromatography for routine monitoring of serum flecainide.

Journal: Journal of pharmaceutical and biomedical analysis 20020822

Title: [Caution in therapy of ventricular extrasystole. Staying safe with electrolytes].

Journal: MMW Fortschritte der Medizin 20020822

Title: Pharmacokinetics and electrocardiographic effects of a new controlled-release form of flecainide acetate: comparison with the standard form and influence of the CYP2D6 polymorphism.

Journal: Clinical pharmacology and therapeutics 20020801

Title: Buccal transport of flecainide and sotalol: effect of a bile salt and ionization state.

Journal: International journal of pharmaceutics 20020708

Title: Inhibition of the current of heterologously expressed HERG potassium channels by flecainide and comparison with quinidine, propafenone and lignocaine.

Journal: British journal of pharmacology 20020701

Title: [Antiarrhythmic drugs in atrial fibrillation].

Journal: La Revue du praticien 20020615

Title: An evaluation of the strategy of maintenance of sinus rhythm by antiarrhythmic drug therapy after ablation and pacing therapy in patients with paroxysmal atrial fibrillation.

Journal: European heart journal 20020601

Title: Clinical value of left atrial appendage flow for prediction of long-term sinus rhythm maintenance in patients with nonvalvular atrial fibrillation.

Journal: Journal of the American College of Cardiology 20020501

Title: Atrial fibrillation recurrence after internal cardioversion: prognostic importance of electrophysiological parameters.

Journal: Heart (British Cardiac Society) 20020501

Title: Hair analysis of flecainide for assessing the individual drug-taking behavior.

Journal: European journal of clinical pharmacology 20020501

Title: Documentation of acute rise in ventricular capture thresholds associated with flecainide acetate.

Journal: Pacing and clinical electrophysiology : PACE 20020501

Title: Transplacental flecainide therapy in the treatment of fetal supraventricular tachycardia.

Journal: Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 20020501

Title: Symptomatic bradycardia secondary to interaction between topical timolol maleate, verapamil, and flecainide: a case report.

Journal: The Journal of emergency medicine 20020401

Title: Amiodarone used in successful resuscitation after near-fatal flecainide overdose.

Journal: Resuscitation 20020401

Title: Flecainide augments muscle sympathetic nerve activity in humans.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20020401

Title: Limited antifibrillatory effectiveness of clinically relevant concentrations of class I antiarrhythmics in isolated perfused rat hearts.

Journal: Journal of cardiovascular pharmacology 20020301

Title: Lack of interaction between amiodarone and mexiletine in cardiac arrhythmia patients.

Journal: Journal of clinical pharmacology 20020301

Title: Flecainide and sotalol: a new combination therapy for refractory supraventricular tachycardia in children <1 year of age.

Journal: Journal of the American College of Cardiology 20020206

Title: Excitatory mechanism of deflationary slowly adapting pulmonary stretch receptors in the rat lung.

Journal: The Journal of pharmacology and experimental therapeutics 20020201

Title: Flecainide in the intrauterine treatment of fetal supraventricular tachycardia.

Journal: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 20020201

Title: Highlights of the 22nd French pharmacovigilance meeting.

Journal: Prescrire international 20020201

Title: Drug treatment of fetal tachycardias.

Journal: Paediatric drugs 20020101

Title: Risk of mortality in a cohort of patients newly diagnosed with chronic atrial fibrillation.

Journal: BMC cardiovascular disorders 20020101

Title: Diffuse infiltrative lung disease associated with flecainide. Report of two cases.

Journal: Respiration; international review of thoracic diseases 20020101

Title: Impact of stereoselectivity on the pharmacokinetics and pharmacodynamics of antiarrhythmic drugs.

Journal: Clinical pharmacokinetics 20020101

Title: Meta-analysis of flecainide safety in patients with supraventricular arrhythmias.

Journal: Arzneimittel-Forschung 20020101

Title: Use of beta-blockers in atrial fibrillation.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20020101

Title: Electrophysiological evaluation of Wolff-Parkinson-White syndrome.

Journal: Indian pacing and electrophysiology journal 20020101

Title: Non-pharmacological treatment of atrial fibrillation.

Journal: Indian pacing and electrophysiology journal 20020101

Title: Novel SCN5A mutation leading either to isolated cardiac conduction defect or Brugada syndrome in a large French family.

Journal: Circulation 20011218

Title: Flecainide toxicity: cause and contribution to death.

Journal: Legal medicine (Tokyo, Japan) 20011201

Title: Measurement of flecainide in hair as an index of drug exposure.

Journal: Journal of pharmaceutical sciences 20011101

Title: Amiodarone -- waxed and waned and waxed again.

Journal: Expert opinion on pharmacotherapy 20011101

Title: [Brugada syndrome].

Journal: La Tunisie medicale 20011101

Title: Effects of potassium channel and Na+-Ca2+ exchange blockers on the responses of slowly adapting pulmonary stretch receptors to hyperinflation in flecainide-treated rats.

Journal: British journal of pharmacology 20011001

Title: Supraventricular tachycardia with hydrops in a 27-week premature baby.

Journal: International journal of clinical practice 20011001

Title: Asymptomatic brugada syndrome case unmasked during dimenhydrinate infusion.

Journal: Journal of cardiovascular electrophysiology 20011001

Title: HPLC of basic drugs on microparticulate strong cation-exchange materials - a review.

Journal: Forensic science international 20010915

Title: [Intermittent atrial fibrillation. An 'idiopathic' emergency. Torsade de pointes].

Journal: MMW Fortschritte der Medizin 20010913

Title: Gating-dependent mechanisms for flecainide action in SCN5A-linked arrhythmia syndromes.

Journal: Circulation 20010904

Title: Flecainide widens the excitable gap at pivot points of premature turning wavefronts in rabbit ventricular myocardium.

Journal: Journal of cardiovascular electrophysiology 20010901

Title: Quinidine induced electrocardiographic normalization in two patients with Brugada syndrome.

Journal: Pacing and clinical electrophysiology : PACE 20010901

Title: Optical measurement of cell-to-cell coupling in intact heart using subthreshold electrical stimulation.

Journal: American journal of physiology. Heart and circulatory physiology 20010801

Title: Flecainide reverses neuropathic pain and suppresses ectopic nerve discharge in rats.

Journal: Neuroreport 20010703

Title: The effects of flecainide on ATP-sensitive K(+) channels in pig urethral myocytes.

Journal: British journal of pharmacology 20010701

Title: Acute loss of capture due to flecainide acetate.

Journal: Pacing and clinical electrophysiology : PACE 20010701

Title: [Protocols for the treatment of supraventricular tachycardias in the fetus].

Journal: Nederlands tijdschrift voor geneeskunde 20010623

Title: Permanent junctional reciprocating tachycardia in infants and children: effectiveness of medical and non-medical treatment.

Journal: Italian heart journal : official journal of the Italian Federation of Cardiology 20010601

Title: Transplacental treatment of fetal tachycardia: implications of drug transporting proteins in placenta.

Journal: Seminars in perinatology 20010601

Title: [Interstitial pneumopathy due to flecainide].

Journal: Presse medicale (Paris, France : 1983) 20010601

Title: Regulation of KChIP2 potassium channel beta subunit gene expression underlies the gradient of transient outward current in canine and human ventricle.

Journal: The Journal of physiology 20010515

Title: Response to flecainide infusion predicts long-term success of hybrid pharmacologic and ablation therapy in patients with atrial fibrillation.

Journal: Journal of the American College of Cardiology 20010501

Title: Mechanisms of antiarrhythmic drug action on termination of atrial flutter.

Journal: Pacing and clinical electrophysiology : PACE 20010501

Title: Determination of oral dosage and pharmacokinetic analysis of flecainide in horses.

Journal: The Journal of veterinary medical science 20010501

Title: Exercise induced widening of the QRS complex in a patient on flecainide.

Journal: Heart (British Cardiac Society) 20010401

Title: Class IC antiarrhythmic drug induced atrial flutter: electrocardiographic and electrophysiological findings and their importance for long term outcome after right atrial isthmus ablation.

Journal: Heart (British Cardiac Society) 20010401

Title: Adverse ocular effects of flecainide.

Journal: Acta ophthalmologica Scandinavica 20010401

Title: Normalization of ventricular repolarization with flecainide in long QT syndrome patients with SCN5A:DeltaKPQ mutation.

Journal: Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc 20010401

Title: Successful extracorporeal life support in a case of severe flecainide intoxication.

Journal: Critical care medicine 20010401

Title: Prenatal diagnosis of the Wolf-Parkinson-White-syndrome by fetal magnetocardiography.

Journal: BJOG : an international journal of obstetrics and gynaecology 20010301

Title: [Long QT syndrome and Brugada syndrome: 2 aspects of the same disease?].

Journal: Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology 20010301

Title: [Supraventricular tachycardia and premature atrial contractions in fetus].

Journal: Nederlands tijdschrift voor geneeskunde 20010217

Title: Idiopathic sustained left ventricular tachycardia in pediatric patients.

Journal: Pediatrics international : official journal of the Japan Pediatric Society 20010201

Title: Single oral loading dose of propafenone for pharmacological cardioversion of recent-onset atrial fibrillation.

Journal: Journal of the American College of Cardiology 20010201

Title: Efficacy and safety of out-of-hospital self-administered single-dose oral drug treatment in the management of infrequent, well-tolerated paroxysmal supraventricular tachycardia.

Journal: Journal of the American College of Cardiology 20010201

Title: Differential effects of dofetilide, amiodarone, and class lc drugs on left and right atrial refractoriness and left atrial vulnerability in pigs.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20010201

Title: ST segment elevation in the right precordial leads following administration of class Ic antiarrhythmic drugs.

Journal: Heart (British Cardiac Society) 20010101

Title: Frequency-dependent electrophysiological effects of flecainide, nifekalant and d,l-sotalol on the human atrium.

Journal: Japanese circulation journal 20010101

Title: Dofetilide: a new class III antiarrhythmic agent.

Journal: The Canadian journal of cardiology 20010101

Title: Transient ST segment elevation in right precordial leads induced by psychotropic drugs: relationship to the Brugada syndrome.

Journal: Journal of cardiovascular electrophysiology 20010101

Title: [Effectiveness and side effects of the treatment with propafenone and flecainide for recent-onset atrial fibrillation].

Journal: Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology 20010101

Title: Torsades de pointes ventricular tachycardia induced by mosapride and flecainide in the presence of hypokalemia.

Journal: Pacing and clinical electrophysiology : PACE 20010101

Title: Syncope in patients with atrial flutter during treatment with class Ic antiarrhythmic drugs.

Journal: Journal of electrocardiology 20010101

Title: Pharmacologic conversion of atrial fibrillation: a systematic review of available evidence.

Journal: Progress in cardiovascular diseases 20010101

Title: [Atrial fibrillation. New views on an old disease].

Journal: Gaceta medica de Mexico 20010101

Title: Analgesic effects of flecainide on postherpetic neuralgia.

Journal: International journal of clinical pharmacology research 20010101

Title: Second-line treatment of fetal supraventricular tachycardia using flecainide acetate.

Journal: Pediatric cardiology 20010101

Title: Brugada syndrome: the syndrome of right bundle branch block, ST segment elevation in V1 to V3 and sudden death.

Journal: Indian pacing and electrophysiology journal 20010101

Title: A re-analysis of our current understanding of isthmus-dependent atrial flutter: some gaps, some hypotheses.

Journal: Indian pacing and electrophysiology journal 20010101

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Tags:99495-90-6 Molecular Formula|99495-90-6 MDL|99495-90-6 SMILES|99495-90-6 R-(-)-Flecainide
Catalog No.: AA01E9DW
99495-90-6,MFCD00869713
99495-90-6 | R-(-)-Flecainide
Pack Size: 1mg
Purity: ≥98%
in stock
$292.00 $204.00
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Technical Information
Catalog Number: AA01E9DW
Chemical Name: R-(-)-Flecainide
CAS Number: 99495-90-6
Molecular Formula: C17H20F6N2O3
Molecular Weight: 414.3427
MDL Number: MFCD00869713
SMILES: O=C(c1cc(OCC(F)(F)F)ccc1OCC(F)(F)F)NC[C@H]1CCCCN1
Properties
Complexity: 500  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 1  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 28  
Hydrogen Bond Acceptor Count: 10  
Hydrogen Bond Donor Count: 2  
Isotope Atom Count: 0  
Rotatable Bond Count: 7  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 3.8  
Literature fold

Title: CYP2D6 genotype affects age-related decline in flecainide clearance: a population pharmacokinetic analysis.

Journal: Pharmacogenetics and genomics20121101

Title: Spinal blockades of class I antiarrythmic drugs with bupivacaine by isobolographic analysis in rats.

Journal: Neuroscience letters20121018

Title: R222Q SCN5A mutation is associated with reversible ventricular ectopy and dilated cardiomyopathy.

Journal: Journal of the American College of Cardiology20121016

Title: [New antiarrhythmic drugs for the treatment of atrial fibrillation].

Journal: Giornale italiano di cardiologia (2006)20121001

Title: ACP Journal Club. Short-term was less effective than long-term flecainide for preventing recurrent AF after cardioversion.

Journal: Annals of internal medicine20120918

Title: Impact of Na⁺ channel blockers on transmural dispersion of refractoriness and arrhythmic susceptibility in guinea-pig left ventricle.

Journal: European journal of pharmacology20120915

Title: Modeling of catecholaminergic polymorphic ventricular tachycardia with patient-specific human-induced pluripotent stem cells.

Journal: Journal of the American College of Cardiology20120911

Title: The role of the anaesthetised guinea-pig in the preclinical cardiac safety evaluation of drug candidate compounds.

Journal: Toxicology and applied pharmacology20120901

Title: Sodium current deficit and arrhythmogenesis in a murine model of plakophilin-2 haploinsufficiency.

Journal: Cardiovascular research20120901

Title: Rapid control of foetal supraventricular tachycardia with digoxin and flecainide combination treatment.

Journal: Cardiology in the young20120801

Title: The long and short of antiarrhythmic drug treatment.

Journal: Lancet (London, England)20120721

Title: Short-term versus long-term antiarrhythmic drug treatment after cardioversion of atrial fibrillation (Flec-SL): a prospective, randomised, open-label, blinded endpoint assessment trial.

Journal: Lancet (London, England)20120721

Title: Effects of ventricular pacing protocol on electrical restitution assessments in guinea-pig heart.

Journal: Experimental physiology20120701

Title: Flecainide suppresses defibrillator-induced storming in catecholaminergic polymorphic ventricular tachycardia.

Journal: Pacing and clinical electrophysiology : PACE20120701

Title: [Supraventricular extrasystole after cardioversion with amiodarone].

Journal: Deutsche medizinische Wochenschrift (1946)20120701

Title: Brugada pattern masquerading as ST-segment elevation myocardial infarction in flecainide toxicity.

Journal: Indian heart journal20120701

Title: [Arrhythmic storm in a patient with Brugada syndrome--an unusual case].

Journal: Harefuah20120701

Title: Feasibility and efficacy of minimally invasive stand-alone surgical ablation of atrial fibrillation. A single-center experience.

Journal: Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing20120601

Title: Does terfenadine-induced ventricular tachycardia/fibrillation directly relate to its QT prolongation and Torsades de Pointes?

Journal: British journal of pharmacology20120601

Title: Should all individuals with a nondiagnostic Brugada-electrocardiogram undergo sodium-channel blocker test?

Journal: Heart rhythm20120601

Title: Nonlinearity between action potential alternans and restitution, which both predict ventricular arrhythmic properties in Scn5a+/- and wild-type murine hearts.

Journal: Journal of applied physiology (Bethesda, Md. : 1985)20120601

Title: Chloroquine terminates stretch-induced atrial fibrillation more effectively than flecainide in the sheep heart.

Journal: Circulation. Arrhythmia and electrophysiology20120601

Title: Letter by Uzun et al regarding article, 'comparison of transplacental treatment of fetal supraventricular tachyarrhythmias with digoxin, flecainide, and sotalol: results of a nonrandomized multicenter study'.

Journal: Circulation20120522

Title: [Severe acute flecainide intoxication].

Journal: Medicina clinica20120512

Title: Field and action potential recordings in heart slices: correlation with established in vitro and in vivo models.

Journal: British journal of pharmacology20120501

Title: SCN1Bb R214Q found in 3 patients: 1 with Brugada syndrome and 2 with lone atrial fibrillation.

Journal: Heart rhythm20120501

Title: The App-Runx1 region is critical for birth defects and electrocardiographic dysfunctions observed in a Down syndrome mouse model.

Journal: PLoS genetics20120501

Title: Capture of the volatile carbonyl metabolite of flecainide on 2,4-dinitrophenylhydrazine cartridge for quantitation by stable-isotope dilution mass spectrometry coupled with chromatography.

Journal: Journal of chromatography. A20120406

Title: Atrial fibrillation with a giant left atrial appendage can be successfully treated with pulmonary vein antrum isolation.

Journal: Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation20120401

Title: Follow-up with exercise test of effort-induced ventricular arrhythmias linked to ryanodine receptor type 2 gene mutations.

Journal: The American journal of cardiology20120401

Title: Effects of a novel amiodarone-like compound SAR114646A on the pig atrium and susceptibility to ventricular fibrillation in dogs and pigs.

Journal: Naunyn-Schmiedeberg's archives of pharmacology20120401

Title: Systematic review and meta-analysis of the efficacy of cardioversion by vernakalant and comparators in patients with atrial fibrillation.

Journal: Cardiovascular drugs and therapy20120401

Title: Convulsions after normal dose of lidocaine: a probable drug interaction.

Journal: British journal of anaesthesia20120401

Title: Sudden cardiac death and inherited channelopathy: the basic electrophysiology of the myocyte and myocardium in ion channel disease.

Journal: Heart (British Cardiac Society)20120401

Title: Safety of flecainide.

Journal: Drug safety20120401

Title: Antiarrhythmic drugs for the maintenance of sinus rhythm: risks and benefits.

Journal: International journal of cardiology20120322

Title: Pathophysiology of the cardiac late Na current and its potential as a drug target.

Journal: Journal of molecular and cellular cardiology20120301

Title: A liquid chromatography-electrospray tandem mass spectrometry method for the determination of antiarrhythmic drugs and their metabolites in forensic whole blood samples.

Journal: Journal of analytical toxicology20120301

Title: Therapeutic approach for patients with catecholaminergic polymorphic ventricular tachycardia: state of the art and future developments.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology20120201

Title: Guidelines for the diagnosis and management of Catecholaminergic Polymorphic Ventricular Tachycardia.

Journal: Heart, lung & circulation20120201

Title: Catecholaminergic polymorphic ventricular tachycardia in a patient with recurrent exertional syncope.

Journal: Korean circulation journal20120201

Title: Atrial flutter in normal heart could be first manifestation of Brugada syndrome.

Journal: Acta cardiologica20120201

Title: Flecainide and antiarrhythmic effects in a mouse model of catecholaminergic polymorphic ventricular tachycardia.

Journal: Trends in cardiovascular medicine20120201

Title: Effects of CYP2D6*10, CYP3A5*3, CYP1A2*1F, and ABCB1 C3435T polymorphisms on the pharmacokinetics of flecainide in healthy Chinese subjects.

Journal: Drug metabolism and drug interactions20120109

Title: Successful elimination of significant arrhythmia burden with flecainide in an adolescent with long QT syndrome type 3.

Journal: Congenital heart disease20120101

Title: Dronedarone for the treatment of atrial fibrillation: a NICE single technology appraisal.

Journal: PharmacoEconomics20120101

Title: Usefulness of postmortem biochemistry in forensic pathology: illustrative case reports.

Journal: Legal medicine (Tokyo, Japan)20120101

Title: The effects of a bidirectional cavo-tricuspid isthmus block in persistent atrial fibrillation.

Journal: Yonsei medical journal20120101

Title: Ionic mechanisms of desflurane on prolongation of action potential duration in rat ventricular myocytes.

Journal: Yonsei medical journal20120101

Title: Skin biopsy-proven flecainide-induced neuropathy.

Journal: Muscle & nerve20120101

Title: Pharmacological interventions in the treatment of the acute effects of cannabis: a systematic review of literature.

Journal: Harm reduction journal20120101

Title: Tinnitus: network pathophysiology-network pharmacology.

Journal: Frontiers in systems neuroscience20120101

Title: Trends in qualifying biomarkers in drug safety. Consensus of the 2011 meeting of the spanish society of clinical pharmacology.

Journal: Frontiers in pharmacology20120101

Title: Cardiac Safety Implications of hNav1.5 Blockade and a Framework for Pre-Clinical Evaluation.

Journal: Frontiers in pharmacology20120101

Title: Macrocephaly-capillary malformation presenting with fetal arrhythmia.

Journal: Pediatric dermatology20120101

Title: Identification of putative potassium channel homologues in pathogenic protozoa.

Journal: PloS one20120101

Title: Molecular Insights into the Local Anesthetic Receptor within Voltage-Gated Sodium Channels Using Hydroxylated Analogs of Mexiletine.

Journal: Frontiers in pharmacology20120101

Title: Cost considerations in the management of atrial fibrillation - impact of dronedarone.

Journal: ClinicoEconomics and outcomes research : CEOR20120101

Title: Congenital giant cardiac tumor with severe left-ventricular inflow and outflow obstruction and arrhythmia treated with pulmonary artery banding and long-term amiodarone infusion.

Journal: Annals of pediatric cardiology20120101

Title: Mexiletine differentially restores the trafficking defects caused by two brugada syndrome mutations.

Journal: Frontiers in pharmacology20120101

Title: Omega-3 Fatty acids: anti-arrhythmic, pro-arrhythmic, or both?

Journal: Frontiers in physiology20120101

Title: Bidirectional ventricular tachycardia: a hallmark of catecholaminergic polymorphic ventricular tachycardia.

Journal: Indian pacing and electrophysiology journal20120101

Title: Expression of ABC Efflux transporters in placenta from women with insulin-managed diabetes.

Journal: PloS one20120101

Title: Diagnostic dilemmas: overlapping features of brugada syndrome and arrhythmogenic right ventricular cardiomyopathy.

Journal: Frontiers in physiology20120101

Title: A linear ablating system in the left and right atrium: feasibility, catheter performance and clinical results.

Journal: Indian pacing and electrophysiology journal20120101

Title: Is the measurement of accessory pathway refractory period reproducible?

Journal: Indian pacing and electrophysiology journal20120101

Title: Effects of flecainide therapy on inappropriate shocks and arrhythmias in catecholaminergic polymorphic ventricular tachycardia.

Journal: Journal of electrocardiology20120101

Title: Decreased milk drinking causing flecainide toxicity in an older child.

Journal: BMJ case reports20120101

Title: A misguided 'pill in the pocket' approach with flecainide leading to cardiac arrest.

Journal: BMJ case reports20120101

Title: [Is the determination of the defibrillation threshold in patients with an implantable cardioverter-defibrillator still required?].

Journal: Herzschrittmachertherapie & Elektrophysiologie20111201

Title: The management of patients with atrial fibrillation and dronedarone's place in therapy.

Journal: Advances in therapy20111201

Title: Medical reversal: why we must raise the bar before adopting new technologies.

Journal: The Yale journal of biology and medicine20111201

Title: Class I antiarrhythmic drugs produced a spinal anesthetic effect in rats.

Journal: Neuroscience letters20111114

Title: New drugs vs. old concepts: a fresh look at antiarrhythmics.

Journal: Pharmacology & therapeutics20111101

Title: Rationale and current perspective for early rhythm control therapy in atrial fibrillation.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology20111101

Title: Efficacy and potency of class I antiarrhythmic drugs for suppression of Ca2+ waves in permeabilized myocytes lacking calsequestrin.

Journal: Journal of molecular and cellular cardiology20111101

Title: K201 (JTV-519) alters the spatiotemporal properties of diastolic Ca(2+) release and the associated diastolic contraction during β-adrenergic stimulation in rat ventricular cardiomyocytes.

Journal: Basic research in cardiology20111101

Title: Pharmacological conversion of recent atrial fibrillation: a randomized, placebo-controlled study of three antiarrhythmic drugs.

Journal: Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology20111101

Title: Fever-induced QTc prolongation and ventricular fibrillation in a healthy young man.

Journal: Yonsei medical journal20111101

Title: [Catheter ablation of paroxysmal atrial fibrillation: extended recommendations considering safety improvements of pulmonary vein isolation with a cryoballoon--Case 11/2011].

Journal: Deutsche medizinische Wochenschrift (1946)20111101

Title: Comparison of transplacental treatment of fetal supraventricular tachyarrhythmias with digoxin, flecainide, and sotalol: results of a nonrandomized multicenter study.

Journal: Circulation20111018

Title: Pharmacological inhibition of the hERG potassium channel is modulated by extracellular but not intracellular acidosis.

Journal: Journal of cardiovascular electrophysiology20111001

Title: Management of atrial fibrillation by primary care physicians in Germany: baseline results of the ATRIUM registry.

Journal: Clinical research in cardiology : official journal of the German Cardiac Society20111001

Title: Postpacing abnormal repolarization in catecholaminergic polymorphic ventricular tachycardia associated with a mutation in the cardiac ryanodine receptor gene.

Journal: Heart rhythm20111001

Title: Refractory dispersion promotes conduction disturbance and arrhythmias in a Scn5a (+/-) mouse model.

Journal: Pflugers Archiv : European journal of physiology20111001

Title: Syncope following 'pill-in-the-pocket' treatment of atrial fibrillation with propafenone plus quinidine.

Journal: Heart (British Cardiac Society)20111001

Title: [Remodeling by atrial fibrillation and clinical implications for cardioversion].

Journal: Deutsche medizinische Wochenschrift (1946)20111001

Title: A novel N440K sodium channel mutation causes myotonia with exercise-induced weakness--exclusion of CLCN1 exon deletion/duplication by MLPA.

Journal: Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology20111001

Title: Mechanism of antiarrhythmic effects of flecainide in catecholaminergic polymorphic ventricular tachycardia.

Journal: Circulation research20110902

Title: Managing patients with ICD shocks and programming tachycardia therapies during acute heart failure syndromes.

Journal: Heart failure reviews20110901

Title: Type I Brugada electrocardiogram pattern induced by metoclopramide.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology20110901

Title: The safety of flecainide treatment of atrial fibrillation: long-term incidence of sudden cardiac death and proarrhythmic events.

Journal: Journal of internal medicine20110901

Title: Update on anti-coagulation in atrial fibrillation.

Journal: QJM : monthly journal of the Association of Physicians20110901

Title: Atypical response of class IC atrial flutter to adenosine.

Journal: Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace20110901

Title: A computational model to predict the effects of class I anti-arrhythmic drugs on ventricular rhythms.

Journal: Science translational medicine20110831

Title: Cardiovascular MRI in clinical trials: expanded applications through novel surrogate endpoints.

Journal: Heart (British Cardiac Society)20110815

Title: Two candidates at the heart of dysfunction: The ryanodine receptor and calcium/calmodulin protein kinase II as potential targets for therapeutic intervention-An in vivo perspective.

Journal: Pharmacology & therapeutics20110801

Title: Impact of dronedarone on hospitalization burden in patients with atrial fibrillation: results from the ATHENA study.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology20110801

Title: Is antiarrhythmic treatment in the elderly different? a review of the specific changes.

Journal: Drugs & aging20110801

Title: Does a Brugada pattern ECG precipitated by excessive-dose flecainide provide a diagnosis of a Brugada syndrome patient and/or contraindicate its use? A case study.

Journal: Circulation. Arrhythmia and electrophysiology20110801

Title: Short communication: flecainide exerts an antiarrhythmic effect in a mouse model of catecholaminergic polymorphic ventricular tachycardia by increasing the threshold for triggered activity.

Journal: Circulation research20110722

Title: Natural history and outcome of hepatic vascular malformations in a large cohort of patients with hereditary hemorrhagic teleangiectasia.

Journal: Digestive diseases and sciences20110701

Title: Perinatal treatment of refractory atrial flutter with hydrops fetalis: a case report.

Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet20110701

Title: Use of intravenous lipid 20% emulsion for the treatment of a voluntary intoxication of flecainide with refractory shock.

Journal: Clinical toxicology (Philadelphia, Pa.)20110701

Title: A 2-year survey of treatment of acute atrial fibrillation in an ED.

Journal: The American journal of emergency medicine20110601

Title: Successful treatment of catecholaminergic polymorphic ventricular tachycardia with flecainide: a case report and review of the current literature.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology20110601

Title: Prevalence of electrocardiographic findings suggestive of sudden cardiac death risk in 10,867 apparently healthy young Korean men.

Journal: Pacing and clinical electrophysiology : PACE20110601

Title: Flecainide therapy reduces exercise-induced ventricular arrhythmias in patients with catecholaminergic polymorphic ventricular tachycardia.

Journal: Journal of the American College of Cardiology20110531

Title: A novel mechanism for LQT3 with 2:1 block: a pore-lining mutation in Nav1.5 significantly affects voltage-dependence of activation.

Journal: Heart rhythm20110501

Title: The ryanodine receptor: a pivotal Ca2+ regulatory protein and potential therapeutic drug target.

Journal: Current drug targets20110501

Title: Mapping of reentrant spontaneous polymorphic ventricular tachycardia in a Scn5a+/- mouse model.

Journal: American journal of physiology. Heart and circulatory physiology20110501

Title: Genetics of sudden cardiac death syndromes.

Journal: Current opinion in cardiology20110501

Title: Inhibition of cardiac Ca2+ release channels (RyR2) determines efficacy of class I antiarrhythmic drugs in catecholaminergic polymorphic ventricular tachycardia.

Journal: Circulation. Arrhythmia and electrophysiology20110401

Title: Comparison of the in vivo hemodynamic effects of the antiarrhythmic agents vernakalant and flecainide in a rat hindlimb perfusion model.

Journal: Journal of cardiovascular pharmacology20110401

Title: Flecainide.

Journal: Acta cardiologica20110401

Title: [Brugada electrocardiographic pattern elicited by flecainide overdose].

Journal: Medicina clinica20110319

Title: Quantitative trait loci for electrocardiographic parameters and arrhythmia in the mouse.

Journal: Journal of molecular and cellular cardiology20110301

Title: Na+ channel distribution and electrophysiological heterogeneities in guinea pig ventricular wall.

Journal: American journal of physiology. Heart and circulatory physiology20110301

Title: Mixed treatment comparison of dronedarone, amiodarone, sotalol, flecainide, and propafenone, for the management of atrial fibrillation.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology20110301

Title: Mixed treatment comparisons for atrial fibrillation: evidence network or bewildering entanglement?

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology20110301

Title: A possible association between takotsubo cardiomyopathy and treatment with flecainide.

Journal: International journal of cardiology20110217

Title: Spatial and temporal heterogeneities are localized to the right ventricular outflow tract in a heterozygotic Scn5a mouse model.

Journal: American journal of physiology. Heart and circulatory physiology20110201

Title: Twenty-five years in the making: flecainide is safe and effective for the management of atrial fibrillation.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology20110201

Title: Biophysical and molecular characterization of a novel de novo KCNJ2 mutation associated with Andersen-Tawil syndrome and catecholaminergic polymorphic ventricular tachycardia mimicry.

Journal: Circulation. Cardiovascular genetics20110201

Title: Flecainide acetate acetic acid solvates.

Journal: Journal of pharmaceutical sciences20110201

Title: Emergency treatment of Wolff-Parkinson-White syndrome.

Journal: Emergency nurse : the journal of the RCN Accident and Emergency Nursing Association20110201

Title: ST-segment elevation in a patient receiving flecainide.

Journal: Archives of internal medicine20110110

Title: Pacemaker malfunction induced by a pharmaco-metabolic 'perfect storm': a brief report.

Journal: Journal of clinical pharmacology20110101

Title: Efficacy of flecainide in a patient with catecholaminergic polymorphic ventricular tachycardia.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology20110101

Title: Catecholaminergic polymorphic ventricular tachycardia: important messages from case reports.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology20110101

Title: Electrophysiologic studies and radiofrequency catheter ablation of ectopic atrial tachycardia in children.

Journal: Pediatric cardiology20110101

Title: Risk stratification in individuals with the Brugada type 1 ECG pattern without previous cardiac arrest: usefulness of a combined clinical and electrophysiologic approach.

Journal: European heart journal20110101

Title: Delayed conduction and its implications in murine Scn5a(+/-) hearts: independent and interacting effects of genotype, age, and sex.

Journal: Pflugers Archiv : European journal of physiology20110101

Title: [Acute flecainide overdose].

Journal: Anales de pediatria (Barcelona, Spain : 2003)20110101

Title: A Case of Isolated Left Ventricular Noncompaction with Basal ECG-Tracing Strongly Suggestive for Type-2 Brugada Syndrome.

Journal: Cardiology research and practice20110101

Title: Translation of flecainide- and mexiletine-induced cardiac sodium channel inhibition and ventricular conduction slowing from nonclinical models to clinical.

Journal: Journal of pharmacological and toxicological methods20110101

Title: Dronedarone: current evidence for its safety and efficacy in the management of atrial fibrillation.

Journal: Drug design, development and therapy20110101

Title: Familial Takayasu arteritis - a pediatric case and a review of the literature.

Journal: Pediatric rheumatology online journal20110101

Title: Impact of sarcoplasmic reticulum calcium release on calcium dynamics and action potential morphology in human atrial myocytes: a computational study.

Journal: PLoS computational biology20110101

Title: Canadian Cardiovascular Society atrial fibrillation guidelines 2010: rate and rhythm management.

Journal: The Canadian journal of cardiology20110101

Title: Mitochondria as crucial players in demyelinated axons: lessons from neuropathology and experimental demyelination.

Journal: Autoimmune diseases20110101

Title: Recapitulation of an ion channel IV curve using frequency components.

Journal: Journal of visualized experiments : JoVE20110101

Title: An Observational, Prospective Survey Assessing the Control of Atrial Fibrillation in Asia Pacific: Rationale and Design of the RecordAF-AP Registry.

Journal: Clinical Medicine Insights. Cardiology20110101

Title: Sex differences in drug disposition.

Journal: Journal of biomedicine & biotechnology20110101

Title: Endurance exercise training reduces cardiac sodium/calcium exchanger expression in animals susceptible to ventricular fibrillation.

Journal: Frontiers in physiology20110101

Title: Left superior pulmonary vein rhythm masquerading as sinus rhythm.

Journal: Indian pacing and electrophysiology journal20110101

Title: Atrial fibrillation and the use of oral bisphosphonates.

Journal: Therapeutics and clinical risk management20110101

Title: The pathology and treatment of cardiac arrhythmias: focus on atrial fibrillation.

Journal: Vascular health and risk management20110101

Title: Pharmacological management of atrial fibrillation: one, none, one hundred thousand.

Journal: Cardiology research and practice20110101

Title: Recent advances in the pathogenesis and drug action in periodic paralyses and related channelopathies.

Journal: Frontiers in pharmacology20110101

Title: Atrial fibrillation (acute onset).

Journal: BMJ clinical evidence20110101

Title: Pharmacodynamic and Pharmacokinetic Interactions of Propranolol with Garlic (Allium sativum) in Rats.

Journal: Evidence-based complementary and alternative medicine : eCAM20110101

Title: Depression in vascular pathologies: the neurologist's point of view.

Journal: Vascular health and risk management20110101

Title: Perioperative atrial fibrillation in five patients - role of anxiety.

Journal: Journal of anaesthesiology, clinical pharmacology20110101

Title: Torsades de pointes during laparoscopic adrenalectomy of a pheochromocytoma: a case report.

Journal: Journal of medical case reports20110101

Title: Management of patients with atrial fibrillation: specific considerations for the old age.

Journal: Cardiology research and practice20110101

Title: Mechanism underlying catecholaminergic polymorphic ventricular tachycardia and approaches to therapy.

Journal: Journal of electrocardiology20110101

Title: Incidence and severity of coronary artery disease in patients with atrial fibrillation undergoing first-time coronary angiography.

Journal: PloS one20110101

Title: Utility of frozen cell lines in medium throughput electrophysiology screening of hERG and NaV1.5 blockade.

Journal: Journal of pharmacological and toxicological methods20110101

Title: Na Channel β Subunits: Overachievers of the Ion Channel Family.

Journal: Frontiers in pharmacology20110101

Title: Skeletal muscle na channel disorders.

Journal: Frontiers in pharmacology20110101

Title: The sodium channel as a target for local anesthetic drugs.

Journal: Frontiers in pharmacology20110101

Title: Targeting GIRK Channels for the Development of New Therapeutic Agents.

Journal: Frontiers in pharmacology20110101

Title: Safety and efficacy of dronedarone in the treatment of atrial fibrillation/flutter.

Journal: Clinical Medicine Insights. Cardiology20110101

Title: Right ventricular dysfunction in patients with Brugada-like electrocardiography: a two dimensional strain imaging study.

Journal: Cardiovascular ultrasound20110101

Title: A patient with mexiletine-related psychosis.

Journal: International journal of general medicine20110101

Title: New methods for the analysis of heartbeat behavior in risk stratification.

Journal: Frontiers in physiology20110101

Title: 'Wait and see' approach to the emergency department cardioversion of acute atrial fibrillation.

Journal: Emergency medicine international20110101

Title: [Congenital junctional ectopic tachycardia. Pharmacologic management during infancy].

Journal: Medicina20110101

Title: The importance of being profiled: improving drug candidate safety and efficacy using ion channel profiling.

Journal: Frontiers in pharmacology20110101

Title: Automatic continuous ECG monitoring system for over-drug detection in Brugada Syndrome.

Journal: Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference20110101

Title: Discovery, characterization, and structure-activity relationships of an inhibitor of inward rectifier potassium (Kir) channels with preference for Kir2.3, Kir3.x, and Kir7.1.

Journal: Frontiers in pharmacology20110101

Title: Genetic Polymorphisms as Risk Stratification Tool in Primary Preventive ICD Therapy.

Journal: ISRN cardiology20110101

Title: Knock-in gain-of-function sodium channel mutation prolongs atrial action potentials and alters atrial vulnerability.

Journal: Heart rhythm20101201

Title: Iatrogenic Flecainide toxicity.

Journal: Heart (British Cardiac Society)20101201

Title: Development of multifocal atrial tachycardia in a patient using aminophylline -A case report-.

Journal: Korean journal of anesthesiology20101201

Title: Neuronal injury in chronic CNS inflammation.

Journal: Best practice & research. Clinical anaesthesiology20101201

Title: Incessant tachycardia following posteroseptal pathway ablation: a pseudo-r' or pseudo-pseudo-r' wave in V1?

Journal: Pacing and clinical electrophysiology : PACE20101101

Title: Optimizing catecholaminergic polymorphic ventricular tachycardia therapy in calsequestrin-mutant mice.

Journal: Heart rhythm20101101

Title: Safety and efficacy of flecainide in the treatment of symptomatic children with Wolff-Parkinson-White syndrome.

Journal: Pediatric cardiology20101101

Title: LQTS gene LOVD database.

Journal: Human mutation20101101

Title: Radiofrequency ablation of coronary sinus-dependent atrial flutter guided by fractionated mid-diastolic coronary sinus potentials.

Journal: Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing20101101

Title: Effectiveness of prophylactic implantation of cardioverter-defibrillators without cardiac resynchronization therapy in patients with ischaemic or non-ischaemic heart disease: a systematic review and meta-analysis.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology20101101

Title: [Flecainide poisoning].

Journal: Revista espanola de anestesiologia y reanimacion20101101

Title: Small dose... big poison.

Journal: Australian family physician20101101

Title: Warfarin toxicity and individual variability-clinical case.

Journal: Toxins20101101

Title: Overlapping binding sites of structurally different antiarrhythmics flecainide and propafenone in the subunit interface of potassium channel Kv2.1.

Journal: The Journal of biological chemistry20101029

Title: Extracorporeal life support in a case of fatal flecainide and betaxolol poisoning allowing successful cardiac allograft.

Journal: Annals of emergency medicine20101001

Title: Regional variations in action potential alternans in isolated murine Scn5a (+/-) hearts during dynamic pacing.

Journal: Acta physiologica (Oxford, England)20101001

Title: Increased right ventricular repolarization gradients promote arrhythmogenesis in a murine model of Brugada syndrome.

Journal: Journal of cardiovascular electrophysiology20101001

Title: Atrial arrhythmogenic properties in wild-type and Scn5a+/- murine hearts.

Journal: Experimental physiology20101001

Title: 'Pill-in-the-pocket' treatment for recent-onset atrial fibrillation.

Journal: Heart (British Cardiac Society)20101001

Title: Management of patients with acute atrial fibrillation in the ED.

Journal: The American journal of emergency medicine20101001

Title: Dronedarone for the treatment of atrial fibrillation and atrial flutter.

Journal: Health technology assessment (Winchester, England)20101001

Title: State of the art in hereditary muscle channelopathies.

Journal: Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology20101001

Title: Flecainide inhibits the stimulatory effect of veratridine on the response of airway mechanoreceptors to maintained inflations in rats.

Journal: Life sciences20100925

Title: In vivo studies of Scn5a+/- mice modeling Brugada syndrome demonstrate both conduction and repolarization abnormalities.

Journal: Journal of electrocardiology20100901

Title: A transthoracic echocardiographic follow-up study after catheter ablation of atrial fibrillation: can we detect pulmonary vein stenosis by transthoracic echocardiography?

Journal: Korean circulation journal20100901

Title: Chronic progressive multiple sclerosis - pathogenesis of neurodegeneration and therapeutic strategies.

Journal: Current neuropharmacology20100901

Title: Computational modelling of the initiation and development of spontaneous intracellular Ca2+ waves in ventricular myocytes.

Journal: Philosophical transactions. Series A, Mathematical, physical, and engineering sciences20100828

Title: Purkinje cells from RyR2 mutant mice are highly arrhythmogenic but responsive to targeted therapy.

Journal: Circulation research20100820

Title: Effects of flecainide and quinidine on action potential and ventricular arrhythmogenic properties in Scn3b knockout mice.

Journal: Clinical and experimental pharmacology & physiology20100801

Title: Pharmacological activation of IKr impairs conduction in guinea pig hearts.

Journal: Journal of cardiovascular electrophysiology20100801

Title: Atrial arrhythmogenicity in aged Scn5a+/DeltaKPQ mice modeling long QT type 3 syndrome and its relationship to Na+ channel expression and cardiac conduction.

Journal: Pflugers Archiv : European journal of physiology20100801

Title: Liquid chromatographic direct resolution of flecainide and its analogs on a chiral stationary phase based on (+)-(18-crown-6)-2,3,11,12-tetracarboxylic acid.

Journal: Chirality20100701

Title: Cardiac sodium channelopathies.

Journal: Pflugers Archiv : European journal of physiology20100701

Title: Autonomic modulation and antiarrhythmic therapy in a model of long QT syndrome type 3.

Journal: Cardiovascular research20100701

Title: Sodium channelopathies of skeletal muscle result from gain or loss of function.

Journal: Pflugers Archiv : European journal of physiology20100701

Title: Rhythm control agents and adverse events in patients with atrial fibrillation.

Journal: International journal of clinical practice20100701

Title: Molecular determinants of state-dependent block of voltage-gated sodium channels by pilsicainide.

Journal: British journal of pharmacology20100701

Title: The spectrum of SCN5A gene mutations in Spanish Brugada syndrome patients.

Journal: Revista espanola de cardiologia20100701

Title: Successful thrombolytic therapy with recombinant tissue-type plasminogen activator for massive pulmonary embolism -A case report-.

Journal: Korean journal of anesthesiology20100701

Title: Arrhythmic risk biomarkers for the assessment of drug cardiotoxicity: from experiments to computer simulations.

Journal: Philosophical transactions. Series A, Mathematical, physical, and engineering sciences20100628

Title: Flecainide for cardioversion in patients at elevated cardiovascular risk and persistent atrial fibrillation: a prospective observational study.

Journal: Clinical research in cardiology : official journal of the German Cardiac Society20100601

Title: Congenital long QT syndrome and 2:1 atrioventricular block: an optimistic outcome in the current era.

Journal: Heart rhythm20100601

Title: Substrate and Trigger Ablation for Reduction of Atrial Fibrillation (STAR AF): a randomized, multicentre, international trial.

Journal: European heart journal20100601

Title: Management of persistent wide QRS in flecainide overdose with magnesium sulphate.

Journal: Emergency medicine journal : EMJ20100601

Title: A mathematical model to understand the mechanisms of action of class 1 antiarrhythmic drugs.

Journal: Indian journal of pharmacology20100601

Title: Impact of the control of symptomatic paroxysmal atrial fibrillation on health-related quality of life.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology20100501

Title: Predicting drug-induced slowing of conduction and pro-arrhythmia: identifying the 'bad' sodium current blockers.

Journal: British journal of pharmacology20100501

Title: Increase in organization index predicts atrial fibrillation termination with flecainide post-ablation: spectral analysis of intracardiac electrograms.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology20100401

Title: Termination of atrial fibrillation by flecainide: mechanistic insights from spectral analysis.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology20100401

Title: Intravenous administration of flecainide or propafenone in patients with recent-onset atrial fibrillation does not predict adverse effects during 'pill-in-the-pocket' treatment.

Journal: Heart (British Cardiac Society)20100401

Title: Changes in the QTc interval after administration of flecainide acetate, with and without coadministered paroxetine, in relation to cytochrome P450 2D6 genotype: data from an open-label, two-period, single-sequence crossover study in healthy Korean male subjects.

Journal: Clinical therapeutics20100401

Title: Tachycardia due to atrial flutter with rapid 1:1 conduction following treatment of atrial fibrillation with flecainide.

Journal: BMJ (Clinical research ed.)20100310

Title: Inhibition of IK,ACh current may contribute to clinical efficacy of class I and class III antiarrhythmic drugs in patients with atrial fibrillation.

Journal: Naunyn-Schmiedeberg's archives of pharmacology20100301

Title: Cardioversion of atrial fibrillation: the use of antiarrhythmic drugs.

Journal: Heart (British Cardiac Society)20100301

Title: Physician stated atrial fibrillation management in light of treatment guidelines: data from an international, observational prospective survey.

Journal: Clinical cardiology20100301

Title: Childhood brugada syndrome in two korean families.

Journal: Korean circulation journal20100301

Title: Supraventricular tachyarrhythmia and Brugada syndrome: a case of atrial fibrillation and Brugada syndrome in a young patient without structural heart disease.

Journal: The West Indian medical journal20100301

Title: [Instead of long-term antiarrhythmia drug treatment--stand-by therapy for atrial fibrillation].

Journal: MMW Fortschritte der Medizin20100218

Title: Flecainide inhibits arrhythmogenic Ca2+ waves by open state block of ryanodine receptor Ca2+ release channels and reduction of Ca2+ spark mass.

Journal: Journal of molecular and cellular cardiology20100201

Title: Tpeak-Tend interval and Tpeak-Tend/QT ratio as markers of ventricular tachycardia inducibility in subjects with Brugada ECG phenotype.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology20100201

Title: An antidote for calcium leak: targeting molecular arrhythmia mechanisms.

Journal: Journal of molecular and cellular cardiology20100201

Title: Drug-drug interaction between oxycodone and adjuvant analgesics in blood-brain barrier transport and antinociceptive effect.

Journal: Journal of pharmaceutical sciences20100101

Title: Postmortem acidification of blood/organs induces an increase in flecainide concentration in cardiac blood and the contribution of the lungs to this increase.

Journal: Journal of analytical toxicology20100101

Title: Successful use of a rapid response team in the pediatric oncology outpatient setting.

Journal: Joint Commission journal on quality and patient safety20100101

Title: Congenital short QT syndrome.

Journal: Indian pacing and electrophysiology journal20100101

Title: Ganglionic plexus ablation during pulmonary vein isolation--predisposing to ventricular arrhythmias?

Journal: Indian pacing and electrophysiology journal20100101

Title: Lower lid entropion secondary to treatment with alpha-1a receptor antagonist: a case report.

Journal: Journal of medical case reports20100101

Title: EVITA: a tool for the early evaluation of pharmaceutical innovations with regard to therapeutic advantage.

Journal: BMC clinical pharmacology20100101

Title: Atypical ST segment elevation and ventricular fibrillation without structural heart disease: a new electrocardiographic presentation of a channelopathy?

Journal: Cardiology20100101

Title: Reporting bias in medical research - a narrative review.

Journal: Trials20100101

Title: Systematic reviews, systematic error and the acquisition of clinical knowledge.

Journal: BMC medical research methodology20100101

Title: Risk stratification in young patients with channelopathies.

Journal: Indian pacing and electrophysiology journal20100101

Title: Ventricular tachycardia in pregnant patients.

Journal: Clinical Medicine Insights. Cardiology20100101

Title: Assessing use-dependent inhibition of the cardiac Na(+/-) current (I(Na)) in the PatchXpress automated patch clamp.

Journal: Journal of pharmacological and toxicological methods20100101

Title: What an emergency physician needs to know about acute care of cardiac arrhythmias.

Journal: Journal of emergencies, trauma, and shock20100101

Title: Tachyarrhythmias, bradyarrhythmias and acute coronary syndromes.

Journal: Journal of emergencies, trauma, and shock20100101

Title: Treating critical supraventricular and ventricular arrhythmias.

Journal: Journal of emergencies, trauma, and shock20100101

Title: Emergency therapy of maternal and fetal arrhythmias during pregnancy.

Journal: Journal of emergencies, trauma, and shock20100101

Title: Beta1-adrenoceptor polymorphism predicts flecainide action in patients with atrial fibrillation.

Journal: PloS one20100101

Title: Junctional ectopic tachycardia.

Journal: Indian pacing and electrophysiology journal20100101

Title: Sodium channel molecular conformations and antiarrhythmic drug affinity.

Journal: Trends in cardiovascular medicine20100101

Title: Current and emerging therapeutic options for the treatment of chronic chagasic cardiomyopathy.

Journal: Vascular health and risk management20100101

Title: Amiodarone for the treatment and prevention of ventricular fibrillation and ventricular tachycardia.

Journal: Vascular health and risk management20100101

Title: Dronedarone for the treatment of atrial fibrillation and atrial flutter: approval and efficacy.

Journal: Vascular health and risk management20100101

Title: Premature Ventricular Contractions and Non-sustained Ventricular Tachycardia: Association with Sudden Cardiac Death, Risk Stratification, and Management Strategies.

Journal: Indian pacing and electrophysiology journal20100101

Title: Genetic analysis of Brugada syndrome and congenital long-QT syndrome type 3 in the Chinese.

Journal: Journal of cardiovascular disease research20100101

Title: Paroxysmal atrial fibrillation due to bronchogenic cyst.

Journal: Internal medicine (Tokyo, Japan)20100101

Title: Brugada syndrome: Controversies in Risk stratification and Management.

Journal: Indian pacing and electrophysiology journal20100101

Title: A review of the mechanisms of ventricular arrhythmia in brugada syndrome.

Journal: Indian pacing and electrophysiology journal20100101

Title: Emergency diagnosis and management of pediatric arrhythmias.

Journal: Journal of emergencies, trauma, and shock20100101

Title: Classification of drugs based on properties of sodium channel inhibition: a comparative automated patch-clamp study.

Journal: PloS one20100101

Title: New and emerging therapeutic agents for the treatment of fibromyalgia: an update.

Journal: Journal of pain research20100101

Title: Sudden cause of cardiac death-be aware of me: a case report and short review on brugada syndrome.

Journal: Case reports in medicine20100101

Title: General anaesthesia for insertion of an automated implantable cardioverter defibrillator in a child with Brugada and autism.

Journal: Indian journal of anaesthesia20100101

Title: Sudden cardiac death in children and adolescents (excluding Sudden Infant Death Syndrome).

Journal: Annals of pediatric cardiology20100101

Title: Challenging cardiac electrophysiology.

Journal: Frontiers in physiology20100101

Title: Anti- or profibrillatory effects of Na(+) channel blockade depend on the site of application relative to gradients in repolarization.

Journal: Frontiers in physiology20100101

Title: Stereoselective Inhibition of the hERG1 Potassium Channel.

Journal: Frontiers in pharmacology20100101

Title: New-onset atrial fibrillation as first clinical manifestation of latent Brugada syndrome: prevalence and clinical significance.

Journal: European heart journal20091201

Title: What is treatment success in cardiac resynchronization therapy?

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology20091101

Title: Pharmacological changes in cellular Ca2+ homeostasis parallel initiation of atrial arrhythmogenesis in murine Langendorff-perfused hearts.

Journal: Clinical and experimental pharmacology & physiology20091001

Title: A case of flecainide-induced hyponatremia.

Journal: Journal of cardiovascular electrophysiology20091001

Title: Typical atrial flutter can effectively be treated using single one-minute cryoapplications: results from a repeat electrophysiological study.

Journal: Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing20091001

Title: Skeletal muscle channelopathies: new insights into the periodic paralyses and nondystrophic myotonias.

Journal: Current opinion in neurology20091001

Title: Fetal ventricular tachycardia secondary to long QT syndrome treated with maternal intravenous magnesium: case report and review of the literature.

Journal: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology20091001

Title: Persistent idiopathic ventricular tachycardia in a 28-year-old woman.

Journal: Emergency medicine journal : EMJ20091001

Title: CASH as a mnemonic for indications of sodium bicarbonate for sodium channel blocker intoxication.

Journal: The American journal of emergency medicine20091001

Title: Evaluation of risk of falls and orthostatic hypotension in older, long-term topical beta-blocker users.

Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie20090901

Title: Non-invasive imaging of cardiac activation and recovery.

Journal: Annals of biomedical engineering20090901

Title: Life-threatening flecainide intoxication in a young child secondary to medication error.

Journal: The Annals of pharmacotherapy20090901

Title: Electrical storm reversible by isoproterenol infusion in a striking case of early repolarization.

Journal: Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing20090801

Title: Drug-induced Brugada syndrome.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology20090801

Title: Pharmacologic management of atrial fibrillation: established and emerging options.

Journal: Journal of managed care pharmacy : JMCP20090801

Title: Fetal arrhythmia: prenatal diagnosis and perinatal management.

Journal: The journal of obstetrics and gynaecology research20090801

Title: Treatment of atrial fibrillation with antiarrhythmic drugs or radiofrequency ablation: two systematic literature reviews and meta-analyses.

Journal: Circulation. Arrhythmia and electrophysiology20090801

Title: Recent advances in pharmacotherapy of atrial fibrillation.

Journal: Indian journal of pharmacology20090801

Title: Atrial arrhythmogenesis in wild-type and Scn5a+/delta murine hearts modelling LQT3 syndrome.

Journal: Pflugers Archiv : European journal of physiology20090701

Title: Antiarrhythmic therapy and risk of death in patients with atrial fibrillation: a nationwide study.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology20090701

Title: Hyponatremia: disorder of water, not salt.

Journal: Journal of cardiovascular electrophysiology20090701

Title: The organic cation transporter, OCTN1, expressed in the human heart, potentiates antagonism of the HERG potassium channel.

Journal: Journal of cardiovascular pharmacology20090701

Title: Delirium in a patient with toxic flecainide plasma concentrations: the role of a pharmacokinetic drug interaction with paroxetine.

Journal: The Annals of pharmacotherapy20090701

Title: Multiple monophasic shocks improve electrotherapy of ventricular tachycardia in a rabbit model of chronic infarction.

Journal: Heart rhythm20090701

Title: Effects of CYP2D6 genotypes on age-related change of flecainide metabolism: involvement of CYP1A2-mediated metabolism.

Journal: British journal of clinical pharmacology20090701

Title: Effects of antiarrhythmic drugs on the hyperpolarization-activated cyclic nucleotide-gated channel current.

Journal: Journal of pharmacological sciences20090601

Title: Paroxysmal bidirectional ventricular tachycardia with tachycardiomyopathy in a pregnant woman.

Journal: Acta cardiologica20090601

Title: Update: A 60-year-old woman with atrial fibrillation.

Journal: JAMA20090506

Title: Flecainide as first-line treatment for supraventricular tachycardia in newborns.

Journal: Journal of cardiovascular medicine (Hagerstown, Md.)20090501

Title: Pharmacological characteristics and clinical applications of K201.

Journal: Current clinical pharmacology20090501

Title: Clinical and arrhythmic outcomes after implantation of a defibrillator for primary prevention of sudden death in patients with post-myocardial infarction cardiomyopathy: The Survey to Evaluate Arrhythmia Rate in High-risk MI patients (SEARCH-MI).

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology20090401

Title: The Registry of the German Competence NETwork on Atrial Fibrillation: patient characteristics and initial management.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology20090401

Title: A preliminary assessment of the effects of ATI-2042 in subjects with paroxysmal atrial fibrillation using implanted pacemaker methodology.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology20090401

Title: Involvement of voltage-gated sodium channels blockade in the analgesic effects of orphenadrine.

Journal: Pain20090401

Title: Waveform characterization of atrial fibrillation using phase information.

Journal: IEEE transactions on bio-medical engineering20090401

Title: Flecainide prevents catecholaminergic polymorphic ventricular tachycardia in mice and humans.

Journal: Nature medicine20090401

Title: Flecainide toxicity in an older adult.

Journal: Journal of the American Geriatrics Society20090401

Title: Aconite poisoning.

Journal: Clinical toxicology (Philadelphia, Pa.)20090401

Title: An enhancement of coronary blood flow in a fetus with supraventricular tachycardia.

Journal: Prenatal diagnosis20090301

Title: Provocation of silence.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology20090301

Title: Flecainide overdose causing a Brugada-type pattern on electrocardiogram in a previously well patient.

Journal: The American journal of emergency medicine20090301

Title: Tinnitus: characteristics, causes, mechanisms, and treatments.

Journal: Journal of clinical neurology (Seoul, Korea)20090301

Title: Arrhythmogenic actions of the Ca2+ channel agonist FPL-64716 in Langendorff-perfused murine hearts.

Journal: Experimental physiology20090201

Title: Bullous fixed drug eruption caused by flecainide.

Journal: Journal of the American Academy of Dermatology20090201

Title: Effects of intrapericardial sotalol and flecainide on transmural atrial electrophysiology and atrial fibrillation.

Journal: Journal of cardiovascular electrophysiology20090201

Title: A dangerous secret.

Journal: The American journal of medicine20090201

Title: Surrogate end points and their role in clinical trial.

Journal: Indian journal of pharmacology20090201

Title: Endurance sport practice as a risk factor for atrial fibrillation and atrial flutter.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology20090101

Title: Panoramic imaging reveals basic mechanisms of induction and termination of ventricular tachycardia in rabbit heart with chronic infarction: implications for low-voltage cardioversion.

Journal: Heart rhythm20090101

Title: Ventricular fibrillation with prominent early repolarization associated with a rare variant of KCNJ8/KATP channel.

Journal: Journal of cardiovascular electrophysiology20090101

Title: Is flecainide dangerous in long QT-3 patients?

Journal: Pacing and clinical electrophysiology : PACE20090101

Title: Brugada ECG pattern precipitated by acute pneumonia: a case report.

Journal: Cases journal20090101

Title: Distinct functional defect of three novel Brugada syndrome related cardiac sodium channel mutations.

Journal: Journal of biomedical science20090101

Title: Isthmus dependent atrial flutter cycle length correlates with right atrial cross-sectional area.

Journal: Indian pacing and electrophysiology journal20090101

Title: Clinical pharmacokinetic and pharmacodynamic profile of cinacalcet hydrochloride.

Journal: Clinical pharmacokinetics20090101

Title: Characterization of voltage-gated potassium channels in human neural progenitor cells.

Journal: PloS one20090101

Title: Arrhythmogenic right ventricular cardiomyopathy presenting with intra-operative aborted sudden cardiac death and TakotsuboLike left ventricular functional abnormalities.

Journal: Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese20090101

Title: Brugada-type ECG pattern in patients treated with oral flecainide for lone atrial fibrillation: is there any clinical implication?

Journal: Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese20090101

Title: Extracorporeal life support in severe drug intoxication: a retrospective cohort study of seventeen cases.

Journal: Critical care (London, England)20090101

Title: CMR findings in patients with hypertrophic cardiomyopathy and atrial fibrillation.

Journal: Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance20090101

Title: The use of oral ranolazine to convert new or paroxysmal atrial fibrillation: a review of experience with implications for possible 'pill in the pocket' approach to atrial fibrillation.

Journal: Indian pacing and electrophysiology journal20090101

Title: Drugs associated with more suicidal ideations are also associated with more suicide attempts.

Journal: PloS one20090101

Title: Polymorphism of human cytochrome P450 2D6 and its clinical significance: Part I.

Journal: Clinical pharmacokinetics20090101

Title: A Novel SCN5A Mutation in a Patient with Coexistence of Brugada Syndrome Traits and Ischaemic Heart Disease.

Journal: Case reports in medicine20090101

Title: Atrial fibrillation in cardiac channelopathies.

Journal: Indian pacing and electrophysiology journal20090101

Title: Short-term and long-term success of electrical cardioversion in atrial fibrillation in managed care system.

Journal: International archives of medicine20090101

Title: Electrocardiographic changes in a rare case of flecainide poisoning: a case report.

Journal: Cases journal20090101

Title: Risk stratification for sudden cardiac death: current approaches and predictive value.

Journal: Current cardiology reviews20090101

Title: Drugs impact on CYP-450 enzyme family: A pharmacogenetical study of response variation.

Journal: Indian journal of human genetics20090101

Title: Radiofrequency ablation in an infant with recurrent supraventricular tachycardia and cyanosis.

Journal: Annals of pediatric cardiology20090101

Title: ECG findings in fatal flecainide intoxication.

Journal: BMJ case reports20090101

Title: [Treatment of atrial fibrillation in every days practice].

Journal: Der Internist20081201

Title: Letter by Behr and Camm regarding article, 'Induced Brugada-type electrocardiogram, a sign for imminent malignant arrhythmias'.

Journal: Circulation20081118

Title: [Current strategies in the treatment of atrial fibrillation].

Journal: Medizinische Klinik (Munich, Germany : 1983)20081115

Title: Is atrial fibrillation with very short cycle length suitable for ablation? A case report.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology20081101

Title: Pharmacokinetic interaction of flecainide and paroxetine in relation to the CYP2D6*10 allele in healthy Korean subjects.

Journal: British journal of clinical pharmacology20081101

Title: ECGs in the ED.

Journal: Pediatric emergency care20081101

Title: Physiological consequences of the P2328S mutation in the ryanodine receptor (RyR2) gene in genetically modified murine hearts.

Journal: Acta physiologica (Oxford, England)20081001

Title: Relationship between subjective symptoms and trans-telephonic ECG findings in patients with symptomatic paroxysmal atrial fibrillation and flutter.

Journal: Journal of cardiology20081001

Title: A mutation in the sodium channel is responsible for the association of long QT syndrome and familial atrial fibrillation.

Journal: Heart rhythm20081001

Title: Scn3b knockout mice exhibit abnormal ventricular electrophysiological properties.

Journal: Progress in biophysics and molecular biology20081001

Title: Effect of prenatal antiarrhythmic treatment on cardiac function in a twin pregnancy.

Journal: Pacing and clinical electrophysiology : PACE20080901

Title: Lidocaine-induced Brugada syndrome phenotype linked to a novel double mutation in the cardiac sodium channel.

Journal: Circulation research20080815

Title: Reduction of complex ventricular ectopy and improvement in exercise capacity with flecainide therapy in Andersen-Tawil syndrome.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology20080801

Title: The Relationship Between HIV Infection and Cardiovascular Disease.

Journal: Current cardiology reviews20080801

Title: The E1784K mutation in SCN5A is associated with mixed clinical phenotype of type 3 long QT syndrome.

Journal: The Journal of clinical investigation20080602

Title: [Drug-related neuropathies: analysis of the French Adverse Drug Reaction Database 1995-2005].

Journal: Presse medicale (Paris, France : 1983)20080601

Title: Effects of MiRP1 and DPP6 beta-subunits on the blockade induced by flecainide of Kv4.3/KChIP2 channels.

Journal: British journal of pharmacology20080601

Title: Atrial fibrillation in pregnancy.

Journal: European journal of obstetrics, gynecology, and reproductive biology20080501

Title: Effects of potassium channel openers in the isolated perfused hypokalaemic murine heart.

Journal: Acta physiologica (Oxford, England)20080501

Title: Paroxysmal reciprocating supraventricular tachycardia in infants: electrophysiologically guided medical treatment and long-term evolution of the re-entry circuit.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology20080501

Title: Treatment of new-onset atrial fibrillation in noncardiac intensive care unit patients: a systematic review of randomized controlled trials.

Journal: Critical care medicine20080501

Title: Use of bepridil in combination with Ic antiarrhythmic agent in converting persistent atrial fibrillation to sinus rhythm.

Journal: Circulation journal : official journal of the Japanese Circulation Society20080501

Title: Induced Brugada-type electrocardiogram, a sign for imminent malignant arrhythmias.

Journal: Circulation20080408

Title: [Bradycardia due to blocked atrial bigeminy: ECG].

Journal: Revue medicale suisse20080402

Title: Pharmacological separation of early afterdepolarizations from arrhythmogenic substrate in DeltaKPQ Scn5a murine hearts modelling human long QT 3 syndrome.

Journal: Acta physiologica (Oxford, England)20080401

Title: A case of Commotio cordis in a young child caused by a fall.

Journal: Resuscitation20080401

Title: Mechanisms underlying increased right ventricular conduction sensitivity to flecainide challenge.

Journal: Cardiovascular research20080301

Title: The cardiac persistent sodium current: an appealing therapeutic target?

Journal: British journal of pharmacology20080301

Title: Clinical and electrophysiological characteristics of patients having atrial flutter with 1:1 atrioventricular conduction.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology20080301

Title: Neonatal rat cardiac fibroblasts express three types of voltage-gated K+ channels: regulation of a transient outward current by protein kinase C.

Journal: American journal of physiology. Heart and circulatory physiology20080201

Title: The challenge of fetal dysrhythmias: echocardiographic diagnosis and clinical management.

Journal: Journal of cardiovascular medicine (Hagerstown, Md.)20080201

Title: Pharmacogenetics: data, concepts and tools to improve drug discovery and drug treatment.

Journal: European journal of clinical pharmacology20080201

Title: Flecainide suppresses bidirectional ventricular tachycardia and reverses tachycardia-induced cardiomyopathy in Andersen-Tawil syndrome.

Journal: Journal of cardiovascular electrophysiology20080101

Title: Criteria for arrhythmogenicity in genetically-modified Langendorff-perfused murine hearts modelling the congenital long QT syndrome type 3 and the Brugada syndrome.

Journal: Pflugers Archiv : European journal of physiology20080101

Title: Choice of cardiac tissue in vitro plays an important role in assessing the risk of drug-induced cardiac arrhythmias in human: beyond QT prolongation.

Journal: Journal of pharmacological and toxicological methods20080101

Title: A randomized comparison of amiodarone and class IC antiarrhythmic drugs to treat atrial fibrillation in patients paced for sinus node disease: the Prevention Investigation and Treatment: A Group for Observation and Research on Atrial arrhythmias (PITAGORA) trial.

Journal: American heart journal20080101

Title: Functional and pharmacological characterization of a Shal-related K+ channel subunit in Zebrafish.

Journal: BMC physiology20080101

Title: Spontaneous alternans in Brugada ST-segment morphology within minutes.

Journal: Journal of electrocardiology20080101

Title: Effect of drugs on defibrillation capacity.

Journal: Drugs20080101

Title: Flecainide: safety and efficacy.

Journal: Cardiology20080101

Title: Paranoid psychosis and myoclonus: flecainide toxicity in renal failure.

Journal: Cardiology20080101

Title: Dual ventricular response or 1 : 2 atrioventricular conduction in dual atrioventricular nodal physiology.

Journal: Indian pacing and electrophysiology journal20080101

Title: Pharmacological therapy in children with atrioventricular reentry: which drug?

Journal: Current pharmaceutical design20080101

Title: Pharmacological therapy in children with nodal reentry tachycardia: when, how and how long to treat the affected patients.

Journal: Current pharmaceutical design20080101

Title: [Circumferential pulmonary vein ablation versus antiarrhythmic drug therapy in paroxysmal atrial fibrillation. Results of the APAF trial].

Journal: Kardiologiia20080101

Title: Epidemiology of arrhythmias in children.

Journal: Indian pacing and electrophysiology journal20080101

Title: Pediatric electrophysiology in India: a sub-speciality come of age.

Journal: Indian pacing and electrophysiology journal20080101

Title: Indications for electrophysiology study in children.

Journal: Indian pacing and electrophysiology journal20080101

Title: Protein C as a surrogate end-point for clinical trials of sepsis.

Journal: Critical care (London, England)20080101

Title: Laugh syncope as a rare sub-type of the situational syncopes: a case report.

Journal: Journal of medical case reports20080101

Title: Postmortem increase of flecainide level in cardiac blood.

Journal: Journal of analytical toxicology20080101

Title: The effect of ranolazine on maintaining sinus rhythm in patients with resistant atrial fibrillation.

Journal: Indian pacing and electrophysiology journal20080101

Title: Brugada syndrome during physical therapy: a case report.

Journal: Cases journal20080101

Title: Diagnosis, treatment, observation and outcome of fetal supraventricular tachycardia in a twin pregnancy.

Journal: Fetal diagnosis and therapy20080101

Title: The prince and the pauper. A tale of anticancer targeted agents.

Journal: Molecular cancer20080101

Title: Atrial fibrillation (acute onset).

Journal: BMJ clinical evidence20080101

Title: Long QT syndrome: A therapeutic challenge.

Journal: Annals of pediatric cardiology20080101

Title: Tachyarrhythmia: Presenting symptom of cardiac tumour.

Journal: Images in paediatric cardiology20080101

Title: The molecular basis of high-affinity binding of the antiarrhythmic compound vernakalant (RSD1235) to Kv1.5 channels.

Journal: Molecular pharmacology20071201

Title: ECG findings in fatal flecainide intoxication.

Journal: Heart (British Cardiac Society)20071201

Title: Flecainide for the treatment of chronic neuropathic pain: a Phase II trial.

Journal: Palliative medicine20071201

Title: [Clinical case of the month. Atrial flutter with rapid ventricular response (1:1 atrioventricular conduction) caused by flecaïnide].

Journal: Revue medicale de Liege20071201

Title: Different effects of antiarrhythmic drugs on the rate-dependency of QT interval: a study with amiodarone and flecainide.

Journal: Journal of cardiovascular pharmacology20071101

Title: Gender-associated differences in pharmacokinetics and anti-arrhythmic effects of flecainide in Japanese patients with supraventricular tachyarrhythmia.

Journal: European journal of clinical pharmacology20071001

Title: A quantitative analysis of the effect of cycle length on arrhythmogenicity in hypokalaemic Langendorff-perfused murine hearts.

Journal: Pflugers Archiv : European journal of physiology20070901

Title: Separation of early afterdepolarizations from arrhythmogenic substrate in the isolated perfused hypokalaemic murine heart through modifiers of calcium homeostasis.

Journal: Acta physiologica (Oxford, England)20070901

Title: Impact of serum flecainide level on control of atrial fibrillation in a case treated with cardiac resynchronization therapy.

Journal: Journal of clinical pharmacy and therapeutics20070801

Title: Novel mutation in the SCN5A gene associated with arrhythmic storm development during acute myocardial infarction.

Journal: Heart rhythm20070801

Title: Treatment of chronic atrial fibrillation in the horse with flecainide: personal observation.

Journal: Veterinary research communications20070801

Title: Reduction of dispersion of repolarization and prolongation of postrepolarization refractoriness explain the antiarrhythmic effects of quinidine in a model of short QT syndrome.

Journal: Journal of cardiovascular electrophysiology20070601

Title: Quinidine in short QT syndrome: an old drug for a new disease.

Journal: Journal of cardiovascular electrophysiology20070601

Title: Effects of flecainide and quinidine on arrhythmogenic properties of Scn5a+/- murine hearts modelling the Brugada syndrome.

Journal: The Journal of physiology20070515

Title: Simultaneous determination of 6 beta-blockers, 3 calcium-channel antagonists, 4 angiotensin-II antagonists and 1 antiarrhythmic drug in post-mortem whole blood by automated solid phase extraction and liquid chromatography mass spectrometry. Method development and robustness testing by experimental design.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20070501

Title: Flecainide cardiotoxicity precipitated by electrolyte imbalance. Caution with thiazide diuretics.

Journal: Emergency medicine journal : EMJ20070501

Title: Further evidence of inherited long QT syndrome gene mutations in antiarrhythmic drug-associated torsades de pointes.

Journal: Heart rhythm20070501

Title: The pharmacological response of ischemia-related atrial fibrillation in dogs: evidence for substrate-specific efficacy.

Journal: Cardiovascular research20070401

Title: A common SCN5A variant alters the responsiveness of human sodium channels to class I antiarrhythmic agents.

Journal: Journal of cardiovascular electrophysiology20070401

Title: The cutaneous analgesic effect of class I antiarrhythmic drugs.

Journal: Anesthesia and analgesia20070401

Title: Flecainide for recurrent malignant ventricular arrhythmias in two siblings with Andersen-Tawil syndrome.

Journal: Heart rhythm20070401

Title: Managing cardiovascular collapse in severe flecainide overdose without recourse to extracorporeal therapy.

Journal: Emergency medicine Australasia : EMA20070401

Title: Some patients with paroxysmal atrial fibrillation should carry flecainide or propafenone to self treat.

Journal: BMJ (Clinical research ed.)20070324

Title: Simultaneous ST-segment elevation in the right precordial and inferior leads in Brugada syndrome.

Journal: Journal of cardiovascular medicine (Hagerstown, Md.)20070301

Title: Dose-response effect of flecainide in patients with symptomatic paroxysmal atrial fibrillation and/or flutter monitored with trans-telephonic electrocardiography: a multicenter, placebo-controlled, double-blind trial.

Journal: Circulation journal : official journal of the Japanese Circulation Society20070301

Title: Brugada-like electrocardiographic pattern and ventricular fibrillation in a patient with primary hyperparathyroidism.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology20070301

Title: [Effect of flecainide on longitudinal and transverse conduction velocities in ventricular myocardium. An experimental study].

Journal: Revista espanola de cardiologia20070301

Title: Haemolysis alters plasma flecainide levels in newborn infants.

Journal: Acta paediatrica (Oslo, Norway : 1992)20070301

Title: Observations on the safety and effectiveness of dofetilide in patients with paroxysmal atrial fibrillation and normal left ventricular function.

Journal: Journal of cardiovascular pharmacology and therapeutics20070301

Title: Neuropsychiatric consequences of cardiovascular medications.

Journal: Dialogues in clinical neuroscience20070301

Title: Kv1.5 is a major component underlying the A-type potassium current in retinal arteriolar smooth muscle.

Journal: American journal of physiology. Heart and circulatory physiology20070201

Title: Familial clustering of lone atrial fibrillation in patients with saddleback-type ST-segment elevation in right precordial leads.

Journal: European heart journal20070201

Title: Torsades de pointes complicating atrioventricular block: evidence for a genetic predisposition.

Journal: Heart rhythm20070201

Title: Anti-arrhythmic effects of I (Na), I (Kr), and combined I (Kr)-I (CaL) blockade in an experimental model of acute stretch-related atrial fibrillation.

Journal: Cardiovascular drugs and therapy20070201

Title: Torsade-de-pointes in a patient under flecainide treatment, an unusual case of proarrhythmicity.

Journal: International journal of cardiology20070108

Title: In silico assessment of Y1795C and Y1795H SCN5A mutations: implication for inherited arrhythmogenic syndromes.

Journal: American journal of physiology. Heart and circulatory physiology20070101

Title: Effects of flecainide and quinidine on arrhythmogenic properties of Scn5a+/Delta murine hearts modelling long QT syndrome 3.

Journal: The Journal of physiology20070101

Title: Do your patients suffer from excessive yawning?

Journal: Acta psychiatrica Scandinavica20070101

Title: Clinical review: aggressive management and extracorporeal support for drug-induced cardiotoxicity.

Journal: Critical care (London, England)20070101

Title: Action potential experiments complete hERG assay and QT-interval measurements in cardiac preclinical studies.

Journal: Journal of pharmacological and toxicological methods20070101

Title: Steroids in late ARDS?

Journal: Critical care (London, England)20070101

Title: Simultaneous separation of 14 antiarrhythmic drugs and determination of mexiletine and flecainide by capillary zone electrophoresis.

Journal: Journal of AOAC International20070101

Title: [Brugada syndrome and work place: two case report].

Journal: Giornale italiano di medicina del lavoro ed ergonomia20070101

Title: A novel and lethal de novo LQT-3 mutation in a newborn with distinct molecular pharmacology and therapeutic response.

Journal: PloS one20070101

Title: [New strategies in the treatment of atrial fibrillation].

Journal: Anales de la Real Academia Nacional de Medicina20070101

Title: Planning a clinical research study.

Journal: Indian journal of orthopaedics20070101

Title: Overlap syndrome of cardiac sodium channel disease in mice carrying the equivalent mutation of human SCN5A-1795insD.

Journal: Circulation20061212

Title: A randomized trial of circumferential pulmonary vein ablation versus antiarrhythmic drug therapy in paroxysmal atrial fibrillation: the APAF Study.

Journal: Journal of the American College of Cardiology20061205

Title: Long-term protection of central axons with phenytoin in monophasic and chronic-relapsing EAE.

Journal: Brain : a journal of neurology20061201

Title: [Be careful in using flecainide by hemodialyzed patients].

Journal: Nephrologie & therapeutique20061201

Title: Auto-intoxication with flecainide and quinapril: ECG-changes, symptoms and treatment.

Journal: Acta cardiologica20061201

Title: Use of telemedicine in the diagnosis of paroxysmal atrial fibrillation and to monitor the effect of antiarrhythmic drug therapy.

Journal: Herzschrittmachertherapie & Elektrophysiologie20061201

Title: Effect of amiodarone on the serum concentration/dose ratio of metoprolol in patients with cardiac arrhythmia.

Journal: Drug metabolism and pharmacokinetics20061201

Title: Altered Na+ channels promote pause-induced spontaneous diastolic activity in long QT syndrome type 3 myocytes.

Journal: Circulation research20061124

Title: [What is your diagnosis? Brugada syndrome].

Journal: Praxis20061122

Title: Properties of a time-dependent potassium current in pig atrium: evidence for a role of kv1.5 in repolarization.

Journal: The Journal of pharmacology and experimental therapeutics20061101

Title: Effect of CYP2D6 genotype on flecainide pharmacokinetics in Japanese patients with supraventricular tachyarrhythmia.

Journal: European journal of clinical pharmacology20061101

Title: Transthoracic tissue Doppler imaging of the atria: a novel method to determine the atrial fibrillation cycle length.

Journal: Journal of cardiovascular electrophysiology20061101

Title: Pharmacological and molecular evidence for the involvement of Kv4.3 in ultra-fast activating K+ currents in murine portal vein myocytes.

Journal: British journal of pharmacology20061101

Title: Negative flecainide test in Brugada syndrome patients with previous positive response.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology20061001

Title: Determinants of sudden cardiac death in patients with persistent atrial fibrillation in the rate control versus electrical cardioversion (RACE) study.

Journal: The American journal of cardiology20061001

Title: [Atrioventricular nodal reentry tachycardia in children].

Journal: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke20060921

Title: Diabetes mellitus reduces the antiarrhythmic effect of ion channel blockers.

Journal: Anesthesia and analgesia20060901

Title: Atrial fibrillation: choosing an antiarrhythmic drug.

Journal: Current cardiology reports20060901

Title: Fetal and maternal magnetocardiography during flecainide therapy for supraventricular tachycardia.

Journal: Obstetrics and gynecology20060901

Title: Diagnostic value of flecainide testing in unmasking SCN5A-related Brugada syndrome.

Journal: Journal of cardiovascular electrophysiology20060801

Title: Flecainide sensitivity of a Na channel long QT mutation shows an open-channel blocking mechanism for use-dependent block.

Journal: American journal of physiology. Heart and circulatory physiology20060701

Title: Flecainide treatment of fetal tachycardia and hydrops fetalis in a twin pregnancy.

Journal: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology20060701

Title: [Permanent His-bundle pacing in patients with infra-Hisian atrioventricular block].

Journal: Revista espanola de cardiologia20060601

Title: [Flecainide acetate utilisation review among general practitioners and hospital or office-based cardiologists in France. Obepine: observational study of flecainide].

Journal: Annales de cardiologie et d'angeiologie20060601

Title: Serial cardioversion by class IC Drugs during 4 months of persistent atrial fibrillation in the goat.

Journal: Journal of cardiovascular electrophysiology20060601

Title: Too little, too late: chasing atrial fibrillation with sodium channel antagonists.

Journal: Journal of cardiovascular electrophysiology20060601

Title: [Life-threatening ventricular tachycardia during flecainide treatment for symptomatic atrial fibrillation in a patient with a structural cardiac disorder].

Journal: Nederlands tijdschrift voor geneeskunde20060506

Title: [Intravenous flecainide administration for conversion of paroxysmal atrial fibrillation in the emergency room].

Journal: Harefuah20060501

Title: Verapamil-sensitive ventricular tachycardia in an infant.

Journal: Congenital heart disease20060501

Title: [Drug treatment of atrial fibrillation].

Journal: MMW Fortschritte der Medizin20060413

Title: Tolerability and safety of fluvoxamine and other antidepressants.

Journal: International journal of clinical practice20060401

Title: Brugada-like electrocardiogram pattern: how to stratify the risk for sudden cardiac death. Is sports activity contraindicated?

Journal: Journal of cardiovascular medicine (Hagerstown, Md.)20060401

Title: Combined use of 1C and III agents for highly symptomatic, refractory atrial fibrillation.

Journal: Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing20060401

Title: Actions of flecainide on susceptibility to phase-2 ventricular arrhythmias during infarct evolution in rat isolated perfused hearts.

Journal: British journal of pharmacology20060301

Title: A case of acute ventricular capture threshold rise associated with flecainide acetate.

Journal: Yonsei medical journal20060227

Title: Class Ic antiarrhythmics block human skeletal muscle Na channel during myotonia-like stimulation.

Journal: European journal of pharmacology20060217

Title: Different glibenclamide-sensitivity of ATP-sensitive K+ currents using different patch-clamp recording methods.

Journal: European journal of pharmacology20060215

Title: Brugada-type ECG association with unexpected sick sinus syndrome.

Journal: Pacing and clinical electrophysiology : PACE20060201

Title: [Flecainide controlled-release for prevention of atrial fibrillation relapse].

Journal: Archives des maladies du coeur et des vaisseaux20060201

Title: Medications used to manage supraventricular tachycardia in the infant a North American survey.

Journal: Pediatric cardiology20060101

Title: An avoidable antiarrhythmic side effect.

Journal: British journal of hospital medicine (London, England : 2005)20060101

Title: High-resolution analysis of the surface P wave as a measure of atrial electrophysiological substrate.

Journal: Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc20060101

Title: Successful conversion of equine atrial fibrillation using oral flecainide.

Journal: Journal of veterinary internal medicine20060101

Title: Cardiac effects of ST-6, a novel cyclohexane dicarboximide derivative.

Journal: Cardiovascular drug reviews20060101

Title: Short- and long-term experience in pulmonary vein segmental ostial ablation for paroxysmal atrial fibrillation.

Journal: Indian pacing and electrophysiology journal20060101

Title: Andersen-Tawil syndrome.

Journal: Indian pacing and electrophysiology journal20060101

Title: Atrial fibrillation and pacing algorithms.

Journal: Indian pacing and electrophysiology journal20060101

Title: Brugada syndrome.

Journal: Orphanet journal of rare diseases20060101

Title: Brugada syndrome unmasked by sodium channel blockade.

Journal: Indian heart journal20060101

Title: Primary prevention of fatal ventricular arrhythmias with implantable cardioverter-defibrillator therapy--an analysis of implications based on MADIT II criteria.

Journal: McGill journal of medicine : MJM : an international forum for the advancement of medical sciences by students20060101

Title: Oxidative mediated lipid peroxidation recapitulates proarrhythmic effects on cardiac sodium channels.

Journal: Circulation research20051209

Title: Atrial fibrillation (recent onset).

Journal: Clinical evidence20051201

Title: [Atrial flutter and fibrillation].

Journal: Praxis20051109

Title: Analysis of current management of atrial fibrillation in the acute setting: GEFAUR-1 study.

Journal: Annals of emergency medicine20051101

Title: Targeted pharmacological reversal of electrical remodeling after cardioversion--rationale and design of the Flecainide Short-Long (Flec-SL) trial.

Journal: American heart journal20051101

Title: [Electrocardiographic findings typical of Brugada syndrome unmasked by cocaine consumption].

Journal: Revista espanola de cardiologia20051101

Title: Warming and response to contractile agents in calf cardiac vein: role of the Ca2+, KCa2+, and Na+ ion channel blockers.

Journal: Methods and findings in experimental and clinical pharmacology20051101

Title: Systemic administration of local anesthetic agents to relieve neuropathic pain.

Journal: The Cochrane database of systematic reviews20051019

Title: Pediatric radiofrequency catheter ablation: results of initial 100 consecutive cases including congenital heart anomalies.

Journal: Journal of Korean medical science20051001

Title: Short QT syndrome. Genotype-phenotype correlations.

Journal: Journal of electrocardiology20051001

Title: Safety and efficacy of flecainide in subjects with Long QT-3 syndrome (DeltaKPQ mutation): a randomized, double-blind, placebo-controlled clinical trial.

Journal: Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc20051001

Title: Low-energy radiofrequency catheter ablation as therapy for supraventricular tachycardia in a premature neonate.

Journal: European journal of pediatrics20050901

Title: Molecular and pharmacological characteristics of transient voltage-dependent K+ currents in cultured human pulmonary arterial smooth muscle cells.

Journal: British journal of pharmacology20050901

Title: Flecainide-induced neuropathy.

Journal: The Annals of pharmacotherapy20050901

Title: Clinical and electrophysiologic profile of Brugada syndrome in Iranian patients.

Journal: Asian cardiovascular & thoracic annals20050901

Title: A novel nonsense mutation in the SCN5A gene leads to Brugada syndrome and a silent gene mutation carrier state.

Journal: The Canadian journal of cardiology20050901

Title: [Flecainide overdose: report of a case].

Journal: Anales de medicina interna (Madrid, Spain : 1984)20050901

Title: A cautionary tale: the risks of flecainide treatment for myotonic dystrophy.

Journal: Journal of clinical neuromuscular disease20050901

Title: Short QT syndrome.

Journal: Cardiovascular research20050815

Title: A single residue in the S6 transmembrane domain governs the differential flecainide sensitivity of voltage-gated potassium channels.

Journal: Molecular pharmacology20050801

Title: Successful use of an intravenous infusion of flecainide and amiodarone for a refractory combination of postoperative junctional and ectopic tachycardias.

Journal: Cardiology in the young20050801

Title: Successful treatment of tachycardia-induced cardiomyopathy with LVAD in a 12-year-old boy.

Journal: The Annals of thoracic surgery20050801

Title: Pharmacologic control of ventricular rate: American College of Chest Physicians guidelines for the prevention and management of postoperative atrial fibrillation after cardiac surgery.

Journal: Chest20050801

Title: Consequences of atrial electrical remodeling for the anti-arrhythmic action of class IC and class III drugs.

Journal: Cardiovascular research20050701

Title: Diphenhydramine overdose and Brugada sign.

Journal: Pacing and clinical electrophysiology : PACE20050701

Title: Predictors of atrial antitachycardia pacing efficacy in patients affected by brady-tachy form of sick sinus syndrome and implanted with a DDDRP device.

Journal: Journal of cardiovascular electrophysiology20050701

Title: Atrial fibrillation recurrence after drug-induced typical atrial flutter ablation.

Journal: Italian heart journal : official journal of the Italian Federation of Cardiology20050701

Title: Narrow QRS complex tachycardia with a high-frequency potential recorded near the His bundle: what is the mechanism?

Journal: Heart rhythm20050601

Title: [Pharmacogenetic study of the response to flecainide and propafenone in patients with atrial fibrillation].

Journal: Revista espanola de cardiologia20050601

Title: Class I antiarrhythmics inhibit Na+ absorption and Cl- secretion in rabbit descending colon epithelium.

Journal: Naunyn-Schmiedeberg's archives of pharmacology20050601

Title: [Outpatient treatment of recurrent atrial fibrillation with the 'pill-in-the-pocket' approach: practical aspects].

Journal: Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology20050601

Title: Expert Canadian consensus suggestions on the rational, clinical use of ziprasidone in the treatment of schizophrenia and related psychotic disorders.

Journal: Neuropsychiatric disease and treatment20050601

Title: The effects of putative K+ channel blockers on volume regulation of murine spermatozoa.

Journal: Biology of reproduction20050501

Title: Pharmacologic prophylaxis for postoperative atrial tachyarrhythmia in general thoracic surgery: evidence from randomized clinical trials.

Journal: The Journal of thoracic and cardiovascular surgery20050501

Title: [Reason for worry: syncope in the morning].

Journal: MMW Fortschritte der Medizin20050421

Title: [Acute treatment of stable hemodynamically tolerable ventricular tachycardia].

Journal: Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS20050401

Title: Pilot study: Noninvasive monitoring of oral flecainide's effects on atrial electrophysiology during persistent human atrial fibrillation using the surface electrocardiogram.

Journal: Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc20050401

Title: The 'pill-in-the-pocket' approach to atrial fibrillation.

Journal: The New England journal of medicine20050317

Title: Electrophysiological effects of flecainide and sotalol in the human atrium during persistent atrial fibrillation.

Journal: Basic research in cardiology20050301

Title: Long-term follow-up after radiofrequency catheter ablation of atrial fibrillation: role of the acute procedure outcome and of the clinical presentation.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology20050301

Title: [Prevalence of Brugada syndrome among 35,309 inhabitants of Lorraine screened at a preventive medicine centre].

Journal: Archives des maladies du coeur et des vaisseaux20050301

Title: Does flecainide regain its antiarrhythmic activity after electrical cardioversion of persistent atrial fibrillation?

Journal: Heart rhythm20050301

Title: Intravenous drug challenge using flecainide and ajmaline in patients with Brugada syndrome.

Journal: Heart rhythm20050301

Title: Are all sodium channel blockers created equal? Clinical-basic correlations based on observations in Brugada syndrome.

Journal: Heart rhythm20050301

Title: Antiarrhythmic drugs in patients with recurrent atrial fibrillation: where are we?

Journal: Italian heart journal : official journal of the Italian Federation of Cardiology20050301

Title: Can recent-onset atrial fibrillation be safely and successfully treated with self-administered antiarrhythmic drugs?

Journal: Nature clinical practice. Cardiovascular medicine20050301

Title: Time-frequency analysis of the surface electrocardiogram for monitoring antiarrhythmic drug effects in atrial fibrillation.

Journal: The American journal of cardiology20050215

Title: Appropriate dosing of antiarrhythmic drugs in Japan requires therapeutic drug monitoring.

Journal: Journal of clinical pharmacy and therapeutics20050201

Title: Spontaneous T wave alternans in a patient with Brugada syndrome--responses to intravenous administration of class I antiarrhythmic drug, glucose tolerance test, and atrial pacing.

Journal: Journal of cardiovascular electrophysiology20050201

Title: [Combination therapy for fetal supraventricular tachycardia with flecainide and digoxin].

Journal: Zeitschrift fur Geburtshilfe und Neonatologie20050201

Title: Brugada syndrome--an update.

Journal: Chang Gung medical journal20050201

Title: Axonal protection in experimental autoimmune neuritis by the sodium channel blocking agent flecainide.

Journal: Brain : a journal of neurology20050101

Title: Recurrent cardiac events in patients with idiopathic ventricular fibrillation, excluding patients with the Brugada syndrome.

Journal: BMC medicine20050101

Title: Assessment of serum flecainide trough levels in patients with tachyarrhythmia.

Journal: The Journal of pharmacy and pharmacology20050101

Title: Efficacy of an implantable cardioverter-defibrillator in a neonate with LQT3 associated arrhythmias.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology20050101

Title: Long-term results of hybrid therapy in patients with atrial fibrillation who develop atrial flutter during flecainide infusion.

Journal: Pacing and clinical electrophysiology : PACE20050101

Title: [Diagnosis and antenatal treatment of fetal arrhythmias].

Journal: Therapeutische Umschau. Revue therapeutique20050101

Title: [Indications for automatic implantable defibrillators in patients with the Brugada syndrome].

Journal: Annales de cardiologie et d'angeiologie20050101

Title: [Atrial fibrillation: choice of the method of pharmacological cardioversion].

Journal: Kardiologiia20050101

Title: Chiropractic as spine care: a model for the profession.

Journal: Chiropractic & osteopathy20050101

Title: [Fetal supraventricular tachyarrhythmias refractory to initial therapy].

Journal: Medicina20050101

Title: Safe and effective pharmacologic management of arrhythmias.

Journal: Texas Heart Institute journal20050101

Title: Transplacental pharmacokinetics of flecainide in the gravid baboon and fetus.

Journal: Pediatric cardiology20050101

Title: Flecainide overdose--support using an intra-aortic balloon pump.

Journal: BMC emergency medicine20050101

Title: Automatic mode switching in atrial fibrillation.

Journal: Indian pacing and electrophysiology journal20050101

Title: Non-linear heart rate variability and risk stratification in cardiovascular disease.

Journal: Indian pacing and electrophysiology journal20050101

Title: Atrial fibrillation and its determinants after radiofrequency ablation of chronic common atrial flutter.

Journal: Indian pacing and electrophysiology journal20050101

Title: Rate-control or rhythm-control: where do we stand?

Journal: Indian pacing and electrophysiology journal20050101

Title: Electrical storms in Brugada syndrome: review of pharmacologic and ablative therapeutic options.

Journal: Indian pacing and electrophysiology journal20050101

Title: Bundle branch reentrant ventricular tachycardia.

Journal: Indian pacing and electrophysiology journal20050101

Title: Ventricular tachycardia in the absence of structural heart disease.

Journal: Indian pacing and electrophysiology journal20050101

Title: Acute lung affection in an endurance-trained man under amiodarone medication.

Journal: German medical science : GMS e-journal20050101

Title: Outpatient treatment of recent-onset atrial fibrillation with the 'pill-in-the-pocket' approach.

Journal: The New England journal of medicine20041202

Title: Flecainide challenge test for the diagnosis of Brugada syndrome.

Journal: Postgraduate medical journal20041201

Title: Synergistic action of atrial dilation and sodium channel blockade on conduction in rabbit atria.

Journal: Journal of cardiovascular electrophysiology20041201

Title: Absorption kinetics and pharmacodynamics of two oral dosage forms of flecainide in patients with an episode of paroxysmal atrial fibrillation.

Journal: European journal of clinical pharmacology20041201

Title: Falls in three patients due to timolol eye drops, tolterodine, and flecainide.

Journal: The journals of gerontology. Series A, Biological sciences and medical sciences20041201

Title: Wide QRS complexes during atrial fibrillation: what is the mechanism?

Journal: Heart rhythm20041201

Title: Flecainide and propafenone induced ST-segment elevation in patients with atrial fibrillation: clue to specificity of Brugada-type electrocardiographic changes.

Journal: The American journal of cardiology20041101

Title: Different clinical courses and predictors of atrial fibrillation occurrence after transisthmic ablation in patients with preablation lone atrial flutter, coexistent atrial fibrillation, and drug induced atrial flutter.

Journal: Pacing and clinical electrophysiology : PACE20041101

Title: Use of intravenous flecainide in horses with naturally-occurring atrial fibrillation.

Journal: Equine veterinary journal20041101

Title: State-dependent trapping of flecainide in the cardiac sodium channel.

Journal: The Journal of physiology20041001

Title: Acute ventricular rate control in atrial fibrillation and atrial flutter.

Journal: International journal of cardiology20041001

Title: Fetal supraventricular tachycardia diagnosed and treated at twenty-four weeks of gestation and after birth: a case report.

Journal: Italian heart journal : official journal of the Italian Federation of Cardiology20041001

Title: Previous therapy with amiodarone increases the recurrence rate in successfully ablated patients with isthmus-dependent atrial flutter.

Journal: Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology20041001

Title: Efficacy of quinidine in high-risk patients with Brugada syndrome.

Journal: Circulation20040928

Title: Limitations to antiarrhythmic drug use in patients with atrial fibrillation.

Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne20040928

Title: Simultaneous determination of serum flecainide and its metabolites by using high performance liquid chromatography.

Journal: Journal of pharmaceutical and biomedical analysis20040903

Title: Dynamic remodeling of K+ and Ca2+ currents in cells that survived in the epicardial border zone of canine healed infarcted heart.

Journal: American journal of physiology. Heart and circulatory physiology20040901

Title: Surface atrial frequency analysis in patients with atrial fibrillation: a tool for evaluating the effects of intervention.

Journal: Journal of cardiovascular electrophysiology20040901

Title: Brugada electrocardiographic pattern elicited by inadvertent flecainide overdose.

Journal: Pacing and clinical electrophysiology : PACE20040901

Title: [Can myocardial Na+ channel gene mutation be a prognostic factor for sudden death in asymptomatic Brugada syndrome?].

Journal: [Hokkaido igaku zasshi] The Hokkaido journal of medical science20040901

Title: Imaging dopamine neurotransmission in Parkinson's disease: biomarker versus surrogate end point.

Journal: Dialogues in clinical neuroscience20040901

Title: Use of ibutilide in cardioversion of patients with atrial fibrillation or atrial flutter treated with class IC agents.

Journal: Journal of the American College of Cardiology20040818

Title: The effects of class Ic antiarrhythmics on tetrodotoxin-resistant Na+ currents in rat sensory neurons.

Journal: Anesthesia and analgesia20040801

Title: Pharmacological cardioversion of recent onset atrial fibrillation.

Journal: European heart journal20040801

Title: Flecainide versus ibutilide for immediate cardioversion of atrial fibrillation of recent onset.

Journal: European heart journal20040801

Title: Atrial fibrillation in rats induced by rapid transesophageal atrial pacing during brief episodes of asphyxia: a new in vivo model.

Journal: Journal of cardiovascular pharmacology20040701

Title: Atrial-selective antiarrhythmic actions of novel Ikur vs. Ikr, Iks, and IKAch class Ic drugs and beta blockers in pigs.

Journal: Medical science monitor : international medical journal of experimental and clinical research20040701

Title: Differentiation of the electrophysiological effects on the atrial myocardium between the pure Na channel blocker, pilsicainide, and flecainide.

Journal: Cardiovascular drugs and therapy20040701

Title: Symptomatic arrhythmia recurrence as an outcome in clinical trials of antiarrhythmic drug therapy.

Journal: Heart rhythm20040701

Title: Role of sodium and calcium channel block in unmasking the Brugada syndrome.

Journal: Heart rhythm20040701

Title: Cardioversion threshold, IRAF and beyond.

Journal: European heart journal20040601

Title: Atrial fibrillation (acute).

Journal: Clinical evidence20040601

Title: Axonal protection using flecainide in experimental autoimmune encephalomyelitis.

Journal: Annals of neurology20040501

Title: Novel therapeutics for treatment of long-QT syndrome and torsade de pointes.

Journal: International journal of cardiology20040501

Title: Short QT syndrome: pharmacological treatment.

Journal: Journal of the American College of Cardiology20040421

Title: Oral antiarrhythmic drugs in converting recent onset atrial fibrillation.

Journal: Pharmacy world & science : PWS20040401

Title: Atrial fibrillation: rate control often better than rhythm control.

Journal: Prescrire international20040401

Title: Delay in right ventricular activation contributes to Brugada syndrome.

Journal: Circulation20040316

Title: Characterization of a fast transient outward current in neocortical neurons from epilepsy patients.

Journal: Journal of neuroscience research20040315

Title: Best evidence topic report. Amiodarone or flecainide for cardioversion in acute onset atrial fibrillation.

Journal: Emergency medicine journal : EMJ20040301

Title: Effects of pretreatment with intravenous flecainide on efficacy of external cardioversion of persistent atrial fibrillation.

Journal: Pacing and clinical electrophysiology : PACE20040301

Title: Phenotypic differences in transient outward K+ current of human and canine ventricular myocytes: insights into molecular composition of ventricular Ito.

Journal: American journal of physiology. Heart and circulatory physiology20040201

Title: Antiarrhythmic drug therapy of atrial fibrillation.

Journal: Cardiology clinics20040201

Title: Different flecainide sensitivity of hNav1.4 channels and myotonic mutants explained by state-dependent block.

Journal: The Journal of physiology20040115

Title: Neonatal intractable atrial flutter successfully treated with intravenous flecainide.

Journal: Pediatric cardiology20040101

Title: Effects of class I antiarrhythmic drugs on the digitalis-induced triggered activity arrhythmia model: a rationale for the short-term use of class I drugs against triggered arrhythmias.

Journal: Heart and vessels20040101

Title: Incidence and management of early recurrent atrial fibrillation (ERAF) after transthoracic electrical cardioversion.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology20040101

Title: Drug-drug interactions between antiarrhythmic drugs in chick embryos.

Journal: Biological & pharmaceutical bulletin20040101

Title: Theoretical possibilities for the development of novel antiarrhythmic drugs.

Journal: Current medicinal chemistry20040101

Title: Pro/con clinical debate: steroids are a key component in the treatment of SARS. Pro: Yes, steroids are a key component of the treatment regimen for SARS.

Journal: Critical care (London, England)20040101

Title: Arrhythmia-provoking factors and symptoms at the onset of paroxysmal atrial fibrillation: a study based on interviews with 100 patients seeking hospital assistance.

Journal: BMC cardiovascular disorders20040101

Title: Clinical review: clinical management of atrial fibrillation - rate control versus rhythm control.

Journal: Critical care (London, England)20040101

Title: Assessment of the dynamics of atrial signals and local atrial period series during atrial fibrillation: effects of isoproterenol administration.

Journal: Biomedical engineering online20040101

Title: Inactivation-deficient human skeletal muscle Na+ channels (hNav1.4-L443C/A444W) in stably transfected HEK-293 cells.

Journal: Receptors & channels20040101

Title: Pharmacological cardioversion of atrial fibrillation: current management and treatment options.

Journal: Drugs20040101

Title: Effects of flecainide on atrial and ventricular refractoriness in rabbits in vitro and in vivo.

Journal: Proceedings of the Western Pharmacology Society20040101

Title: Fetal tachyarrhythmia - part II: treatment.

Journal: Indian pacing and electrophysiology journal20040101

Title: Fetal tachyarrhythmia--part I: Diagnosis.

Journal: Indian pacing and electrophysiology journal20040101

Title: Frequency analysis of atrial fibrillation from the surface electrocardiogram.

Journal: Indian pacing and electrophysiology journal20040101

Title: Management of atrial fibrillation: review of the evidence for the role of pharmacologic therapy, electrical cardioversion, and echocardiography.

Journal: Annals of internal medicine20031216

Title: Ropivacaine combined with various anti-arrhythmic drugs results in mild alterations in myocardial contractility in pigs.

Journal: Canadian journal of anaesthesia = Journal canadien d'anesthesie20031201

Title: Atrial fibrillation (acute).

Journal: Clinical evidence20031201

Title: QT-interval prolongation in right precordial leads: an additional electrocardiographic hallmark of Brugada syndrome.

Journal: Journal of the American College of Cardiology20031105

Title: Flecainide induced ventricular fibrillation in a neonate.

Journal: Heart (British Cardiac Society)20031001

Title: Arrhythmias in the intensive care patient.

Journal: Current opinion in critical care20031001

Title: Frequency measures obtained from the surface electrocardiogram in atrial fibrillation research and clinical decision-making.

Journal: Journal of cardiovascular electrophysiology20031001

Title: Neonatal flecainide toxicity following supraventricular tachycardia treatment.

Journal: The Annals of pharmacotherapy20030901

Title: Flecainide induced ventricular tachycardia (torsades de pointes).

Journal: Pacing and clinical electrophysiology : PACE20030901

Title: Short QT Syndrome: a familial cause of sudden death.

Journal: Circulation20030826

Title: Atrial fibrillation with a very rapid ventricular response as the first clinical arrhythmia in a 76-year-old man.

Journal: Pacing and clinical electrophysiology : PACE20030801

Title: VErapamil plus antiarrhythmic drugs reduce atrial fibrillation recurrences after an electrical cardioversion (VEPARAF Study).

Journal: European heart journal20030801

Title: Risk factors for recurrence of atrial fibrillation in patients undergoing hybrid therapy for antiarrhythmic drug-induced atrial flutter.

Journal: European heart journal20030701

Title: Intravenous flecainide for the treatment of junctional ectopic tachycardia after surgery for congenital heart disease.

Journal: The Annals of thoracic surgery20030701

Title: Electrocardiographic pattern of Brugada syndrome disclosed by a febrile illness: clinical and therapeutic implications.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology20030701

Title: Class I or class III agents for atrial fibrillation: are asking the right question?

Journal: Pacing and clinical electrophysiology : PACE20030701

Title: [Drug therapy of atrial fibrillation].

Journal: Orvosi hetilap20030615

Title: Liquid chromatographic determination of unbound flecainide in therapeutic drug monitoring.

Journal: Journal of pharmaceutical and biomedical analysis20030601

Title: Amiodarone for pharmacological cardioversion of recent-onset atrial fibrillation.

Journal: International journal of cardiology20030601

Title: [Pharmacological interaction between flecainide and benziodarone].

Journal: Revista espanola de cardiologia20030601

Title: [Results of prenatal management of fetuses with supraventricular tachycardia. A series of 66 cases].

Journal: Journal de gynecologie, obstetrique et biologie de la reproduction20030601

Title: Extracellular acidosis modulates drug block of Kv4.3 currents by flecainide and quinidine.

Journal: Journal of cardiovascular electrophysiology20030601

Title: Rhythm versus rate control after ablation and pacing for paroxysmal atrial fibrillation: clinical implications of the PAF 2 trial.

Journal: Cardiac electrophysiology review20030601

Title: Pharmacodynamic equivalence of two flecainide acetate formulations in patients with paroxysmal atrial fibrillation by QRS analysis of ambulatory electrocardiogram.

Journal: Journal of cardiovascular pharmacology20030501

Title: Effects of flecainide on the electrophysiological properties of atrial vulnerability in humans.

Journal: Circulation journal : official journal of the Japanese Circulation Society20030501

Title: Tachycardiac storm in infant with WPW syndrome: 'rescue' radiofrequency ablation.

Journal: Indian pediatrics20030501

Title: Refractoriness and conduction interaction during modulation of non-ischemic ventricular fibrillation by flecainide.

Journal: Cardiovascular drugs and therapy20030501

Title: Neonatal ECG changes caused by supratherapeutic flecainide following treatment for fetal supraventricular tachycardia.

Journal: Heart (British Cardiac Society)20030401

Title: Effects of flecainide and quinidine on Kv4.2 currents: voltage dependence and role of S6 valines.

Journal: British journal of pharmacology20030401

Title: A newly characterized SCN5A mutation underlying Brugada syndrome unmasked by hyperthermia.

Journal: Journal of cardiovascular electrophysiology20030401

Title: Old and new antiarrhythmic drugs for converting and maintaining sinus rhythm in atrial fibrillation: comparative efficacy and results of trials.

Journal: The American journal of cardiology20030320

Title: Pharmacologic and nonpharmacologic options to maintain sinus rhythm: guideline-based and new approaches.

Journal: The American journal of cardiology20030320

Title: Effects of antiarrhythmic drugs on fibrillation in the remodeled atrium: insights into the mechanism of the superior efficacy of amiodarone.

Journal: Circulation20030318

Title: Therapeutic monitoring of class I antiarrhythmic agents using high-resolution electrocardiography instead of blood samples.

Journal: Circulation journal : official journal of the Japanese Circulation Society20030301

Title: Fetal supraventricular tachycardia diagnosed and treated at 13 weeks of gestation: a case report.

Journal: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology20030301

Title: Digoxin remains useful in the management of chronic heart failure.

Journal: The Medical clinics of North America20030301

Title: Detection of proarrhythmia in the female rabbit heart: blinded validation.

Journal: Journal of cardiovascular electrophysiology20030301

Title: Persistent junctional reciprocating tachycardia in the fetus.

Journal: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians20030301

Title: Blockers of sodium and calcium entry protect axons from nitric oxide-mediated degeneration.

Journal: Annals of neurology20030201

Title: Oral loading single dose flecainide for pharmacological cardioversion of recent-onset atrial fibrillation.

Journal: International journal of cardiology20030201

Title: Fetal supraventricular tachycardia: a role for amiodarone as second-line therapy?

Journal: Prenatal diagnosis20030201

Title: Novel brugada SCN5A mutation leading to ST segment elevation in the inferior or the right precordial leads.

Journal: Journal of cardiovascular electrophysiology20030201

Title: Safety of a controlled-release flecainide acetate formulation in the prevention of paroxysmal atrial fibrillation in outpatients.

Journal: Annales de cardiologie et d'angeiologie20030201

Title: [Infusion of flecainide in a patient with atrial fibrillation and latent Brugada's syndrome has determined modifications of the electrocardiogram similar to those of a septal myocardial infarct].

Journal: Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology20030201

Title: Influence of quinidine and flecainide on autonomic nervous activity in thoroughbred horses.

Journal: The Veterinary record20030125

Title: Evaluation of the effect of bepridil on paroxysmal atrial fibrillation: relationship between efficacy and the f-f interval in surface ECG recordings.

Journal: Circulation journal : official journal of the Japanese Circulation Society20030101

Title: [Normal conventional electrocardiogram with negative pharmacological stress test does not rule out Brugada syndrome].

Journal: Revista espanola de cardiologia20030101

Title: Successful treatment of supraventricular tachycardia exhibiting hydrops fetalis with flecainide acetate. A case report.

Journal: Fetal diagnosis and therapy20030101

Title: Analysis of flecainide and two metabolites in biological specimens by HPLC: application to a fatal intoxication.

Journal: Journal of analytical toxicology20030101

Title: Lopinavir/ritonavir: a review of its use in the management of HIV infection.

Journal: Drugs20030101

Title: Bepridil prevents paroxysmal atrial fibrillation by a class III antiarrhythmic drug effect.

Journal: Pacing and clinical electrophysiology : PACE20030101

Title: Flecainide test in Brugada syndrome: a reproducible but risky tool.

Journal: Pacing and clinical electrophysiology : PACE20030101

Title: [Postoperative atrial fibrillation].

Journal: Duodecim; laaketieteellinen aikakauskirja20030101

Title: Mutations in cardiac sodium channels: clinical implications.

Journal: American journal of pharmacogenomics : genomics-related research in drug development and clinical practice20030101

Title: Low-dose flecainide infusion followed by oral pilsicainide is highly effective and safe for paroxysmal atrial fibrillation.

Journal: Cardiovascular drugs and therapy20030101

Title: What caused this wide-complex tachycardia?

Journal: Progress in cardiovascular nursing20030101

Title: [Fetal arrhythmia--own experience].

Journal: Medycyna wieku rozwojowego20030101

Title: Brugada-like electrocardiographic pattern.

Journal: Indian pacing and electrophysiology journal20030101

Title: Congenital junctional ectopic tachycardia: presentation and outcome.

Journal: Indian pacing and electrophysiology journal20030101

Title: Role of atrial fibrillation threshold evaluation on guiding treatment.

Journal: Indian pacing and electrophysiology journal20030101

Title: Brugada disease: chronology of discovery and paternity. Preliminary observations and historical aspects.

Journal: Indian pacing and electrophysiology journal20030101

Title: Preventing sudden death and the use of prophylactic implanted defibrillators.

Journal: Indian pacing and electrophysiology journal20030101

Title: Atrial remodeling: evolving concepts.

Journal: Indian pacing and electrophysiology journal20030101

Title: Importance of left atrial diameter and atrial fibrillatory frequency for conversion of persistent atrial fibrillation with oral flecainide.

Journal: The American journal of cardiology20021101

Title: Transient Brugada-type electrocardiographic abnormalities in renal failure reversed by dialysis.

Journal: Resuscitation20021101

Title: What is the minimal pacing rate that prevents torsades de pointes? Insights from patients with permanent pacemakers.

Journal: Pacing and clinical electrophysiology : PACE20021101

Title: Contribution of Kv4 channels toward the A-type potassium current in murine colonic myocytes.

Journal: The Journal of physiology20021015

Title: Characterization of the A-type potassium current in murine gastric antrum.

Journal: The Journal of physiology20021015

Title: Atrial fibrillation threshold predicted long-term efficacy of pharmacological treatment of patients without structural heart disease.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology20021001

Title: Maintaining stability of sinus rhythm in atrial fibrillation: antiarrhythmic drugs versus ablation.

Journal: Current cardiology reports20020901

Title: A-type potassium currents active at subthreshold potentials in mouse cerebellar Purkinje cells.

Journal: The Journal of physiology20020901

Title: High performance liquid chromatography for routine monitoring of serum flecainide.

Journal: Journal of pharmaceutical and biomedical analysis20020822

Title: [Caution in therapy of ventricular extrasystole. Staying safe with electrolytes].

Journal: MMW Fortschritte der Medizin20020822

Title: Pharmacokinetics and electrocardiographic effects of a new controlled-release form of flecainide acetate: comparison with the standard form and influence of the CYP2D6 polymorphism.

Journal: Clinical pharmacology and therapeutics20020801

Title: Buccal transport of flecainide and sotalol: effect of a bile salt and ionization state.

Journal: International journal of pharmaceutics20020708

Title: Inhibition of the current of heterologously expressed HERG potassium channels by flecainide and comparison with quinidine, propafenone and lignocaine.

Journal: British journal of pharmacology20020701

Title: [Antiarrhythmic drugs in atrial fibrillation].

Journal: La Revue du praticien20020615

Title: An evaluation of the strategy of maintenance of sinus rhythm by antiarrhythmic drug therapy after ablation and pacing therapy in patients with paroxysmal atrial fibrillation.

Journal: European heart journal20020601

Title: Clinical value of left atrial appendage flow for prediction of long-term sinus rhythm maintenance in patients with nonvalvular atrial fibrillation.

Journal: Journal of the American College of Cardiology20020501

Title: Atrial fibrillation recurrence after internal cardioversion: prognostic importance of electrophysiological parameters.

Journal: Heart (British Cardiac Society)20020501

Title: Hair analysis of flecainide for assessing the individual drug-taking behavior.

Journal: European journal of clinical pharmacology20020501

Title: Documentation of acute rise in ventricular capture thresholds associated with flecainide acetate.

Journal: Pacing and clinical electrophysiology : PACE20020501

Title: Transplacental flecainide therapy in the treatment of fetal supraventricular tachycardia.

Journal: Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology20020501

Title: Symptomatic bradycardia secondary to interaction between topical timolol maleate, verapamil, and flecainide: a case report.

Journal: The Journal of emergency medicine20020401

Title: Amiodarone used in successful resuscitation after near-fatal flecainide overdose.

Journal: Resuscitation20020401

Title: Flecainide augments muscle sympathetic nerve activity in humans.

Journal: Circulation journal : official journal of the Japanese Circulation Society20020401

Title: Limited antifibrillatory effectiveness of clinically relevant concentrations of class I antiarrhythmics in isolated perfused rat hearts.

Journal: Journal of cardiovascular pharmacology20020301

Title: Lack of interaction between amiodarone and mexiletine in cardiac arrhythmia patients.

Journal: Journal of clinical pharmacology20020301

Title: Flecainide and sotalol: a new combination therapy for refractory supraventricular tachycardia in children <1 year of age.

Journal: Journal of the American College of Cardiology20020206

Title: Excitatory mechanism of deflationary slowly adapting pulmonary stretch receptors in the rat lung.

Journal: The Journal of pharmacology and experimental therapeutics20020201

Title: Flecainide in the intrauterine treatment of fetal supraventricular tachycardia.

Journal: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology20020201

Title: Highlights of the 22nd French pharmacovigilance meeting.

Journal: Prescrire international20020201

Title: Drug treatment of fetal tachycardias.

Journal: Paediatric drugs20020101

Title: Risk of mortality in a cohort of patients newly diagnosed with chronic atrial fibrillation.

Journal: BMC cardiovascular disorders20020101

Title: Diffuse infiltrative lung disease associated with flecainide. Report of two cases.

Journal: Respiration; international review of thoracic diseases20020101

Title: Impact of stereoselectivity on the pharmacokinetics and pharmacodynamics of antiarrhythmic drugs.

Journal: Clinical pharmacokinetics20020101

Title: Meta-analysis of flecainide safety in patients with supraventricular arrhythmias.

Journal: Arzneimittel-Forschung20020101

Title: Use of beta-blockers in atrial fibrillation.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions20020101

Title: Electrophysiological evaluation of Wolff-Parkinson-White syndrome.

Journal: Indian pacing and electrophysiology journal20020101

Title: Non-pharmacological treatment of atrial fibrillation.

Journal: Indian pacing and electrophysiology journal20020101

Title: Novel SCN5A mutation leading either to isolated cardiac conduction defect or Brugada syndrome in a large French family.

Journal: Circulation20011218

Title: Flecainide toxicity: cause and contribution to death.

Journal: Legal medicine (Tokyo, Japan)20011201

Title: Measurement of flecainide in hair as an index of drug exposure.

Journal: Journal of pharmaceutical sciences20011101

Title: Amiodarone -- waxed and waned and waxed again.

Journal: Expert opinion on pharmacotherapy20011101

Title: [Brugada syndrome].

Journal: La Tunisie medicale20011101

Title: Effects of potassium channel and Na+-Ca2+ exchange blockers on the responses of slowly adapting pulmonary stretch receptors to hyperinflation in flecainide-treated rats.

Journal: British journal of pharmacology20011001

Title: Supraventricular tachycardia with hydrops in a 27-week premature baby.

Journal: International journal of clinical practice20011001

Title: Asymptomatic brugada syndrome case unmasked during dimenhydrinate infusion.

Journal: Journal of cardiovascular electrophysiology20011001

Title: HPLC of basic drugs on microparticulate strong cation-exchange materials - a review.

Journal: Forensic science international20010915

Title: [Intermittent atrial fibrillation. An 'idiopathic' emergency. Torsade de pointes].

Journal: MMW Fortschritte der Medizin20010913

Title: Gating-dependent mechanisms for flecainide action in SCN5A-linked arrhythmia syndromes.

Journal: Circulation20010904

Title: Flecainide widens the excitable gap at pivot points of premature turning wavefronts in rabbit ventricular myocardium.

Journal: Journal of cardiovascular electrophysiology20010901

Title: Quinidine induced electrocardiographic normalization in two patients with Brugada syndrome.

Journal: Pacing and clinical electrophysiology : PACE20010901

Title: Optical measurement of cell-to-cell coupling in intact heart using subthreshold electrical stimulation.

Journal: American journal of physiology. Heart and circulatory physiology20010801

Title: Flecainide reverses neuropathic pain and suppresses ectopic nerve discharge in rats.

Journal: Neuroreport20010703

Title: The effects of flecainide on ATP-sensitive K(+) channels in pig urethral myocytes.

Journal: British journal of pharmacology20010701

Title: Acute loss of capture due to flecainide acetate.

Journal: Pacing and clinical electrophysiology : PACE20010701

Title: [Protocols for the treatment of supraventricular tachycardias in the fetus].

Journal: Nederlands tijdschrift voor geneeskunde20010623

Title: Permanent junctional reciprocating tachycardia in infants and children: effectiveness of medical and non-medical treatment.

Journal: Italian heart journal : official journal of the Italian Federation of Cardiology20010601

Title: Transplacental treatment of fetal tachycardia: implications of drug transporting proteins in placenta.

Journal: Seminars in perinatology20010601

Title: [Interstitial pneumopathy due to flecainide].

Journal: Presse medicale (Paris, France : 1983)20010601

Title: Regulation of KChIP2 potassium channel beta subunit gene expression underlies the gradient of transient outward current in canine and human ventricle.

Journal: The Journal of physiology20010515

Title: Response to flecainide infusion predicts long-term success of hybrid pharmacologic and ablation therapy in patients with atrial fibrillation.

Journal: Journal of the American College of Cardiology20010501

Title: Mechanisms of antiarrhythmic drug action on termination of atrial flutter.

Journal: Pacing and clinical electrophysiology : PACE20010501

Title: Determination of oral dosage and pharmacokinetic analysis of flecainide in horses.

Journal: The Journal of veterinary medical science20010501

Title: Exercise induced widening of the QRS complex in a patient on flecainide.

Journal: Heart (British Cardiac Society)20010401

Title: Class IC antiarrhythmic drug induced atrial flutter: electrocardiographic and electrophysiological findings and their importance for long term outcome after right atrial isthmus ablation.

Journal: Heart (British Cardiac Society)20010401

Title: Adverse ocular effects of flecainide.

Journal: Acta ophthalmologica Scandinavica20010401

Title: Normalization of ventricular repolarization with flecainide in long QT syndrome patients with SCN5A:DeltaKPQ mutation.

Journal: Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc20010401

Title: Successful extracorporeal life support in a case of severe flecainide intoxication.

Journal: Critical care medicine20010401

Title: Prenatal diagnosis of the Wolf-Parkinson-White-syndrome by fetal magnetocardiography.

Journal: BJOG : an international journal of obstetrics and gynaecology20010301

Title: [Long QT syndrome and Brugada syndrome: 2 aspects of the same disease?].

Journal: Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology20010301

Title: [Supraventricular tachycardia and premature atrial contractions in fetus].

Journal: Nederlands tijdschrift voor geneeskunde20010217

Title: Idiopathic sustained left ventricular tachycardia in pediatric patients.

Journal: Pediatrics international : official journal of the Japan Pediatric Society20010201

Title: Single oral loading dose of propafenone for pharmacological cardioversion of recent-onset atrial fibrillation.

Journal: Journal of the American College of Cardiology20010201

Title: Efficacy and safety of out-of-hospital self-administered single-dose oral drug treatment in the management of infrequent, well-tolerated paroxysmal supraventricular tachycardia.

Journal: Journal of the American College of Cardiology20010201

Title: Differential effects of dofetilide, amiodarone, and class lc drugs on left and right atrial refractoriness and left atrial vulnerability in pigs.

Journal: Naunyn-Schmiedeberg's archives of pharmacology20010201

Title: ST segment elevation in the right precordial leads following administration of class Ic antiarrhythmic drugs.

Journal: Heart (British Cardiac Society)20010101

Title: Frequency-dependent electrophysiological effects of flecainide, nifekalant and d,l-sotalol on the human atrium.

Journal: Japanese circulation journal20010101

Title: Dofetilide: a new class III antiarrhythmic agent.

Journal: The Canadian journal of cardiology20010101

Title: Transient ST segment elevation in right precordial leads induced by psychotropic drugs: relationship to the Brugada syndrome.

Journal: Journal of cardiovascular electrophysiology20010101

Title: [Effectiveness and side effects of the treatment with propafenone and flecainide for recent-onset atrial fibrillation].

Journal: Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology20010101

Title: Torsades de pointes ventricular tachycardia induced by mosapride and flecainide in the presence of hypokalemia.

Journal: Pacing and clinical electrophysiology : PACE20010101

Title: Syncope in patients with atrial flutter during treatment with class Ic antiarrhythmic drugs.

Journal: Journal of electrocardiology20010101

Title: Pharmacologic conversion of atrial fibrillation: a systematic review of available evidence.

Journal: Progress in cardiovascular diseases20010101

Title: [Atrial fibrillation. New views on an old disease].

Journal: Gaceta medica de Mexico20010101

Title: Analgesic effects of flecainide on postherpetic neuralgia.

Journal: International journal of clinical pharmacology research20010101

Title: Second-line treatment of fetal supraventricular tachycardia using flecainide acetate.

Journal: Pediatric cardiology20010101

Title: Brugada syndrome: the syndrome of right bundle branch block, ST segment elevation in V1 to V3 and sudden death.

Journal: Indian pacing and electrophysiology journal20010101

Title: A re-analysis of our current understanding of isthmus-dependent atrial flutter: some gaps, some hypotheses.

Journal: Indian pacing and electrophysiology journal20010101

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