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102676-47-1,MFCD02313480
Catalog No.:AA0007ZY

102676-47-1 | Fadrozole

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
95%
in stock  
$27.00   $19.00
- +
5mg
95%
in stock  
$70.00   $49.00
- +
50mg
95%
in stock  
$368.00   $258.00
- +
250mg
95%
in stock  
$776.00   $543.00
- +
1g
95%
in stock  
$1,554.00   $1,088.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA0007ZY
Chemical Name:
Fadrozole
CAS Number:
102676-47-1
Molecular Formula:
C14H13N3
Molecular Weight:
223.2731
MDL Number:
MFCD02313480
SMILES:
N#Cc1ccc(cc1)C1CCCc2n1cnc2
Properties
Computed Properties
 
Complexity:
311  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
17  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
0  
Isotope Atom Count:
0  
Rotatable Bond Count:
1  
Undefined Atom Stereocenter Count:
1  
Undefined Bond Stereocenter Count:
0  
XLogP3:
2.1  

Downstream Synthesis Route
CASUnavailable 
  102676-47-1    147821-42-9 

[1]Furet;Batzl;Bhatnagar;Francotte;Rihs;Lang[JournalofMedicinalChemistry,1993,vol.36,#10,p.1393-1400]

[1]Furet;Batzl;Bhatnagar;Francotte;Rihs;Lang[JournalofMedicinalChemistry,1993,vol.36,#10,p.1393-1400]

[2]CurrentPatentAssignee:DAMIANPHARMAAG;DAMIANPHARMA-WO2018/78049,2018,A1

[3]CurrentPatentAssignee:DAMIANPHARMA-WO2019/211394,2019,A1

[4]CurrentPatentAssignee:DAMIANPHARMA-WO2019/211394,2019,A1

[1]Furet;Batzl;Bhatnagar;Francotte;Rihs;Lang[JournalofMedicinalChemistry,1993,vol.36,#10,p.1393-1400]

[1]Browne,L.J.;Gude,C.;Rodriguez,H.;Steele,R.E.[JournalofMedicinalChemistry,1991,vol.34,#2,p.725-736]

[1]Browne,L.J.;Gude,C.;Rodriguez,H.;Steele,R.E.[JournalofMedicinalChemistry,1991,vol.34,#2,p.725-736]

Literature

Title: Browne LJ, et al. Fadrozole hydrochloride: a potent, selective, nonsteroidal inhibitor of aromatase for the treatment of estrogen-dependent disease. J Med Chem. 1991 Feb;34(2):725-36.

Title: Gunson DE, et al. Prevention of spontaneous tumours in female rats by fadrozole hydrochloride, an aromatase inhibitor. Br J Cancer. 1995 Jul;72(1):72-5.

Title: Morales-Montor J, et al. Inhibition of p-450 aromatase prevents feminisation and induces protection during cysticercosis. Int J Parasitol. 2002 Oct;32(11):1379-87.

Quotation Request
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SDS
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Tags:102676-47-1 Molecular Formula|102676-47-1 MDL|102676-47-1 SMILES|102676-47-1 Fadrozole
Catalog No.: AA0007ZY
102676-47-1,MFCD02313480
102676-47-1 | Fadrozole
Pack Size： 1mg
Purity： 95%
in stock
$27.00 $19.00
Pack Size： 5mg
Purity： 95%
in stock
$70.00 $49.00
Pack Size： 50mg
Purity： 95%
in stock
$368.00 $258.00
Pack Size： 250mg
Purity： 95%
in stock
$776.00 $543.00
Pack Size： 1g
Purity： 95%
in stock
$1,554.00 $1,088.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA0007ZY
Chemical Name: Fadrozole
CAS Number: 102676-47-1
Molecular Formula: C14H13N3
Molecular Weight: 223.2731
MDL Number: MFCD02313480
SMILES: N#Cc1ccc(cc1)C1CCCc2n1cnc2
Properties
Complexity: 311  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 17  
Hydrogen Bond Acceptor Count: 2  
Hydrogen Bond Donor Count: 0  
Isotope Atom Count: 0  
Rotatable Bond Count: 1  
Undefined Atom Stereocenter Count: 1  
Undefined Bond Stereocenter Count: 0  
XLogP3: 2.1  
Downstream Synthesis Route
CASUnavailable 
  102676-47-1    147821-42-9 

[1]Furet;Batzl;Bhatnagar;Francotte;Rihs;Lang[JournalofMedicinalChemistry,1993,vol.36,#10,p.1393-1400]

102676-47-1    102676-87-9 

[1]Furet;Batzl;Bhatnagar;Francotte;Rihs;Lang[JournalofMedicinalChemistry,1993,vol.36,#10,p.1393-1400]

[2]CurrentPatentAssignee:DAMIANPHARMAAG;DAMIANPHARMA-WO2018/78049,2018,A1

[3]CurrentPatentAssignee:DAMIANPHARMA-WO2019/211394,2019,A1

[4]CurrentPatentAssignee:DAMIANPHARMA-WO2019/211394,2019,A1

102676-47-1    102676-86-8 

[1]Furet;Batzl;Bhatnagar;Francotte;Rihs;Lang[JournalofMedicinalChemistry,1993,vol.36,#10,p.1393-1400]

102676-43-7    102676-47-1 

[1]Browne,L.J.;Gude,C.;Rodriguez,H.;Steele,R.E.[JournalofMedicinalChemistry,1991,vol.34,#2,p.725-736]

102676-30-2    102676-47-1 

[1]Browne,L.J.;Gude,C.;Rodriguez,H.;Steele,R.E.[JournalofMedicinalChemistry,1991,vol.34,#2,p.725-736]

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