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117-80-6,MFCD00001677
Catalog No.:AA000DFF

117-80-6 | 2,3-Dichloro-1,4-naphthoquinone

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25g
>95.0%(GC)
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$21.00   $15.00
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500g
>95.0%(GC)
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  • Technical Information
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA000DFF
Chemical Name:
2,3-Dichloro-1,4-naphthoquinone
CAS Number:
117-80-6
Molecular Formula:
C10H4Cl2O2
Molecular Weight:
227.0436
MDL Number:
MFCD00001677
SMILES:
O=C1C(=C(Cl)C(=O)c2c1cccc2)Cl
NSC Number:
537
Properties
Properties
 
BP:
275 °C (2 mmHg)  
Form:
Solid  
MP:
194-197 °C(lit.)  
Refractive Index:
1.5410 (estimate)  
Storage:
Room Temperature;Keep in dry area;  

Computed Properties
 
Complexity:
301  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
2  
XLogP3:
3.4  

Literature

Title: Spectroscopic and theoretical studies on the nucleophilic substitution of 2,3-dichloronaphthoquinone with para-substituted anilines in solid state via initial charge transfer complexation.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20121201

Title: New oxirane derivatives of 1,4-naphthoquinones and their evaluation against T. cruzi epimastigote forms.

Journal: Bioorganic & medicinal chemistry 20120815

Title: Incorporation of a high potential quinone reveals that electron transfer in Photosystem I becomes highly asymmetric at low temperature.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20120601

Title: On the search for potential anti-Trypanosoma cruzi drugs: synthesis and biological evaluation of 2-hydroxy-3-methylamino and 1,2,3-triazolic naphthoquinoidal compounds obtained by click chemistry reactions.

Journal: European journal of medicinal chemistry 20120601

Title: Studies on the synthesis of derivatives of marine-derived bostrycin and their structure-activity relationship against tumor cells.

Journal: Marine drugs 20120401

Title: 2-Sulfanylidene-1,3-dithiolo[4,5-b]naphtho-[2,3-e][1,4]dithiine-5,10-dione.

Journal: Acta crystallographica. Section E, Structure reports online 20111101

Title: Synthesis of balsaminone A, a naturally occurring pentacyclic dinaphthofuran quinone.

Journal: The Journal of organic chemistry 20111007

Title: Prostate cancer risk and exposure to pesticides in British Columbia farmers.

Journal: The Prostate 20110201

Title: Reactions of germenes with various naphthoquinones controlled by substituent effects.

Journal: Dalton transactions (Cambridge, England : 2003) 20100227

Title: Methionine aminopeptidases from Mycobacterium tuberculosis as novel antimycobacterial targets.

Journal: Chemistry & biology 20100129

Title: Reaction of naphthoquinones with substituted nitromethanes. Facile synthesis and antifungal activity of naphtho[2,3-d]isoxazole-4,9-diones.

Journal: Bioorganic & medicinal chemistry letters 20100101

Title: Bacterial growth response to photoactive quinones.

Journal: Photochemistry and photobiology 20100101

Title: Toxicology in the fast lane: application of high-throughput bioassays to detect modulation of key enzymes and receptors.

Journal: Environmental health perspectives 20091201

Title: Kinetics of jack bean urease inhibition by 2,3-dichloro-1,4-naphthoquinone. Elucidation of the mechanism: redox cycling and sulfhydryl arylation.

Journal: Journal of enzyme inhibition and medicinal chemistry 20091001

Title: 2,3-Disubstituted-1,4-naphthoquinones, 12H-benzo[b]phenothiazine-6,11-diones and related compounds: synthesis and biological evaluation as potential antiproliferative and antifungal agents.

Journal: European journal of medicinal chemistry 20090301

Title: New sensitive kinetic spectrophotometric methods for determination of omeprazole in dosage forms.

Journal: International journal of analytical chemistry 20090101

Title: Magnetic particle-based hybrid platforms for bioanalytical sensors.

Journal: Sensors (Basel, Switzerland) 20090101

Title: Charge transfer interaction of 4-acetamidophenol (paracetamol) with 2,3-dichloro-1,4-naphthoquinone: a study in aqueous ethanol medium by UV-vis spectroscopic and DFT methods.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20081201

Title: 3,3-Dimethyl-1,2,3,4,6,11-hexa-hydro-benzo[d]naphtho[2,3-b]furan-1,6,11-trione.

Journal: Acta crystallographica. Section E, Structure reports online 20080801

Title: Screening of 397 chemicals and development of a quantitative structure--activity relationship model for androgen receptor antagonism.

Journal: Chemical research in toxicology 20080401

Title: Indoleamine 2,3-dioxygenase is the anticancer target for a novel series of potent naphthoquinone-based inhibitors.

Journal: Journal of medicinal chemistry 20080327

Title: Hydrides in liquid chloroaluminates.

Journal: The journal of physical chemistry. B 20071206

Title: The 1,4-naphthoquinone scaffold in the design of cysteine protease inhibitors.

Journal: Bioorganic & medicinal chemistry 20070801

Title: Antibacterial activity of Tabebuia impetiginosa Martius ex DC (Taheebo) against Helicobacter pylori.

Journal: Journal of ethnopharmacology 20060421

Title: Interaction of 2,3-dichloro-1,4-naphthoquinone with n-butylamine in halocarbon solvents.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20050601

Title: Selective growth-inhibiting effects of compounds identified in Tabebuia impetiginosa inner bark on human intestinal bacteria.

Journal: Journal of agricultural and food chemistry 20050223

Title: Development and validation of spectrophotometric methods for determination of fluoxetine, sertraline, and paroxetine in pharmaceutical dosage forms.

Journal: Journal of AOAC International 20050101

Title: Study of a reaction between 2,3-dichloro-1,4-naphthoquinone and N,N'-diphenyl thiourea involving an EDA adduct as intermediate.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20040601

Title: Reduction of nitroaromatic pesticides with zero-valent iron.

Journal: Chemosphere 20040101

Title: Synthesis and cytotoxicity of 6,11-dihydro-pyrido- and 6,11-dihydro-benzo[2,3-b]phenazine-6,11-dione derivatives.

Journal: Bioorganic & medicinal chemistry 20030417

Title: Synthesis and cytotoxicity evaluation of 2-amino- and 2-hidroxy-3-ethoxycarbonyl-N-substituted-benzo[f]indole-4,9-dione derivatives.

Journal: Bioorganic & medicinal chemistry 20030403

Title: [Reactions of isopropyl-alkylamine with 2,3-dichloro-1,4-naphthoquinone and 2,3-dichloro-1,4-naphthoquinone/acetaldehyde].

Journal: Die Pharmazie 20030201

Title: 2-(Pyrrolidin-1-yl)-1,4-naphthoquinone and 2-phenylsulfanyl-3-(pyrrolidin-1-yl)-1,4-naphthoquinone.

Journal: Acta crystallographica. Section C, Crystal structure communications 20021201

Title: [Reactions of trialkylamine compounds with 2,3-dichloro-1,4-naphthoquinone].

Journal: Die Pharmazie 20020901

Title: [Reactions between dialkylamine drugs, 2,3-dichloro-1,4-naphthoquinone and acetaldehyde].

Journal: Die Pharmazie 20020801

Title: Synthesis, electrochemical and spectral properties of some omega-N-quinonyl amino acids.

Journal: Amino acids 20020101

Title: Novel N-quinonyl amino acids and their transformation to 3-substituted p-isoxazinones.

Journal: Amino acids 20010101

Title: New quinone-amino acid conjugates linked via a vinylic spacer.

Journal: Amino acids 20010101

Title: 2-chloro-3-substituted-1,4-naphthoquinone inactivators of human cytomegalovirus protease.

Journal: Bioorganic & medicinal chemistry letters 19991004

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