Home Pyridines 115088-06-7
115088-06-7,MFCD20229028
Catalog No.:AA000FSL

115088-06-7 | N-Succinimidyl 4-(2-pyridyldithio)butanoate

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5mg
95%
in stock  
$139.00   $98.00
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10mg
95%
in stock  
$186.00   $130.00
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50mg
95%
in stock  
$337.00   $236.00
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100mg
tech grade
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$436.00   $305.00
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250mg
tech grade
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$847.00   $593.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA000FSL
Chemical Name:
N-Succinimidyl 4-(2-pyridyldithio)butanoate
CAS Number:
115088-06-7
Molecular Formula:
C13H14N2O4S2
Molecular Weight:
326.3913
MDL Number:
MFCD20229028
SMILES:
O=C(ON1C(=O)CCC1=O)CCCSSc1ccccn1
Properties
Computed Properties
 
Complexity:
390  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
21  
Hydrogen Bond Acceptor Count:
7  
Rotatable Bond Count:
8  
XLogP3:
1  

Downstream Synthesis Route

[1]CurrentPatentAssignee:BICYCLETHERAPEUTICSLIMITED-WO2019/34866,2019,A1Locationinpatent:Paragraph00522

[2]Widdison,WayneC.;Wilhelm,SharonD.;Cavanagh,EmilyE.;Whiteman,KathleenR.;Leece,BarbaraA.;Kovtun,Yelena;Goldmacher,VictorS.;Xie,Hongsheng;Steeves,RitaM.;Lutz,RobertJ.;Zhao,Robert;Wang,Lintao;Blättler,WalterA.;Chari,RaviV.J.[JournalofMedicinalChemistry,2006,vol.49,#14,p.4392-4408]

[1]Widdison,WayneC.;Wilhelm,SharonD.;Cavanagh,EmilyE.;Whiteman,KathleenR.;Leece,BarbaraA.;Kovtun,Yelena;Goldmacher,VictorS.;Xie,Hongsheng;Steeves,RitaM.;Lutz,RobertJ.;Zhao,Robert;Wang,Lintao;Blättler,WalterA.;Chari,RaviV.J.[JournalofMedicinalChemistry,2006,vol.49,#14,p.4392-4408]

115088-06-7    796073-69-3   
CASUnavailable 
 
CASUnavailable 

[1]CurrentPatentAssignee:IMMUNOGENINC-WO2007/24222,2007,A1Locationinpatent:Page/Pagecolumn95-97

[1]CurrentPatentAssignee:IMMONUGEN-US2011/313168,2011,A1Locationinpatent:Page/Pagecolumn3-4

Literature

Title: Widdison WC et al. Development of Anilino-Maytansinoid ADCs that Efficiently Release Cytotoxic Metabolitesin Cancer Cells andInduce High Levels of Bystander Killing.Bioconjug Chem, 2015 Nov 18, 26(11):2261-78.

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SDS
Tags:115088-06-7 Molecular Formula|115088-06-7 MDL|115088-06-7 SMILES|115088-06-7 N-Succinimidyl 4-(2-pyridyldithio)butanoate