1190-49-4,MFCD00038143
Catalog No.:AA000OXL

1190-49-4 | L-Homocitrulline

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250mg
98%
in stock  
$9.00   $7.00
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1g
98%
in stock  
$14.00   $10.00
- +
5g
98%
in stock  
$66.00   $47.00
- +
10g
98%
in stock  
$131.00   $92.00
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25g
98%
in stock  
$326.00   $228.00
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  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA000OXL
Chemical Name:
L-Homocitrulline
CAS Number:
1190-49-4
Molecular Formula:
C7H15N3O3
Molecular Weight:
189.2123
MDL Number:
MFCD00038143
SMILES:
NC(=O)NCCCC[C@@H](C(=O)O)N
Properties
Computed Properties
 
Complexity:
184  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
13  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
6  
XLogP3:
-3.9  

Literature

Title: Simultaneous measurement of protein-bound 3-chlorotyrosine and homocitrulline by LC-MS/MS after hydrolysis assisted by microwave: application to the study of myeloperoxidase activity during hemodialysis.

Journal: Talanta 20120915

Title: Impact of carbamylation and glycation of collagen type I on migration of HT1080 human fibrosarcoma cells.

Journal: International journal of oncology 20120601

Title: Quantification of plasma homocitrulline using hydrophilic interaction liquid chromatography (HILIC) coupled to tandem mass spectrometry.

Journal: Analytical and bioanalytical chemistry 20120201

Title: Potential of Novel EPO Derivatives in Limb Ischemia.

Journal: Cardiology research and practice 20120101

Title: Impact of premature birth and critical illness on neonatal range of plasma amino acid concentrations determined by LC-MS/MS.

Journal: Molecular genetics and metabolism 20111201

Title: New device measures atmospheric isocyanic acid.

Journal: Environmental health perspectives 20110801

Title: Dual mechanism of brain damage induced in vivo by the major metabolites accumulating in hyperornithinemia-hyperammonemia-homocitrullinuria syndrome.

Journal: Brain research 20110119

Title: Myeloperoxidase-derived oxidation: mechanisms of biological damage and its prevention.

Journal: Journal of clinical biochemistry and nutrition 20110101

Title: Biological responses to perfluorododecanoic acid exposure in rat kidneys as determined by integrated proteomic and metabonomic studies.

Journal: PloS one 20110101

Title: Erythropoietin: recent developments in the treatment of spinal cord injury.

Journal: Neurology research international 20110101

Title: Anticitrulline antibodies can be caused by homocitrulline-containing proteins in rabbits.

Journal: Arthritis and rheumatism 20101101

Title: Carbamylation-dependent activation of T cells: a novel mechanism in the pathogenesis of autoimmune arthritis.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20100615

Title: In vitro inhibition of low density lipoprotein carbamylation by vitamins, as an ameliorating atherosclerotic risk in uremic patients.

Journal: Scandinavian journal of clinical and laboratory investigation 20100401

Title: Evidence that the major metabolites accumulating in hyperornithinemia-hyperammonemia-homocitrullinuria syndrome induce oxidative stress in brain of young rats.

Journal: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20091101

Title: Experimental evidence that ornithine and homocitrulline disrupt energy metabolism in brain of young rats.

Journal: Brain research 20090929

Title: Retinal degeneration.

Journal: Ophthalmology 20090801

Title: Identification of novel mutations in the SLC25A15 gene in hyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome: a clinical, molecular, and functional study.

Journal: Human mutation 20090501

Title: Phenotypic variability among patients with hyperornithinaemia-hyperammonaemia-homocitrullinuria syndrome homozygous for the delF188 mutation in SLC25A15.

Journal: Journal of medical genetics 20081101

Title: 'O', erythropoietin carbamoylation versus carbamylation.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20080901

Title: Hyperornithinemia-hyperammonemia-homocitrullinuria syndrome (HHH) presenting with acute fulminant hepatic failure.

Journal: Journal of pediatric gastroenterology and nutrition 20080301

Title: Hyperornithinemia-hyperammonemia-homocitrullinuria syndrome with stroke-like imaging presentation: clinical, biochemical and molecular analysis.

Journal: Journal of the neurological sciences 20080115

Title: Acetyl-lysine analog peptides as mechanistic probes of protein deacetylases.

Journal: The Journal of biological chemistry 20071221

Title: Protein carbamylation links inflammation, smoking, uremia and atherogenesis.

Journal: Nature medicine 20071001

Title: 'Multipurpose oxidase' in atherogenesis.

Journal: Nature medicine 20071001

Title: Determination of homocitrulline in urine of patients with HHH syndrome by liquid chromatography tandem mass spectrometry.

Journal: Analytical and bioanalytical chemistry 20061201

Title: HHH syndrome (hyperornithinaemia, hyperammonaemia, homocitrullinuria), with fulminant hepatitis-like presentation.

Journal: Journal of inherited metabolic disease 20060201

Title: Carbamylated low-density lipoprotein induces death of endothelial cells: a link to atherosclerosis in patients with kidney disease.

Journal: Kidney international 20050701

Title: Hyperornithinemia, hyperammonemia, and homocitrullinuria syndrome with evidence of mitochondrial dysfunction due to a novel SLC25A15 (ORNT1) gene mutation in a Palestinian family.

Journal: Journal of the neurological sciences 20040315

Title: The mitochondrial ornithine transporter. Bacterial expression, reconstitution, functional characterization, and tissue distribution of two human isoforms.

Journal: The Journal of biological chemistry 20030829

Title: Cloning and characterization of human ORNT2: a second mitochondrial ornithine transporter that can rescue a defective ORNT1 in patients with the hyperornithinemia-hyperammonemia-homocitrullinuria syndrome, a urea cycle disorder.

Journal: Molecular genetics and metabolism 20030801

Title: [Structure-function relationships of mitochondrial transporters].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20020401

Title: [Mitochondrial ornithine transporter deficiency].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20020401

Title: Seven novel mutations in the ORNT1 gene (SLC25A15) in patients with hyperornithinemia, hyperammonemia, and homocitrullinuria syndrome.

Journal: Human mutation 20011101

Title: Clinical and molecular findings in hyperornithinemia-hyperammonemia-homocitrullinuria syndrome.

Journal: Neurology 20010911

Title: HHH syndrome associated with callosal agenesis and disordered neuronal migration.

Journal: Developmental medicine and child neurology 20010601

Title: Carbamoylation of glomerular and tubular proteins in patients with kidney failure: a potential mechanism of ongoing renal damage.

Journal: Swiss medical weekly 20010324

Title: [Hyperornithinemia-hyperammonemia-homocitrullinuria syndrome].

Journal: Ryoikibetsu shokogun shirizu 20010101

Title: Conscientious metabolic monitoring on a patient with hyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome undergoing anaesthesia.

Journal: Amino acids 20010101

Title: Kato T, et al. Homocitrullinuria and homoargininuria in lysinuric protein intolerance. J Inherit Metab Dis. 1989;12(2):157-61.

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SDS
Tags:1190-49-4 Molecular Formula|1190-49-4 MDL|1190-49-4 SMILES|1190-49-4 L-Homocitrulline
Catalog No.: AA000OXL
1190-49-4,MFCD00038143
1190-49-4 | L-Homocitrulline
Pack Size: 250mg
Purity: 98%
in stock
$9.00 $7.00
Pack Size: 1g
Purity: 98%
in stock
$14.00 $10.00
Pack Size: 5g
Purity: 98%
in stock
$66.00 $47.00
Pack Size: 10g
Purity: 98%
in stock
$131.00 $92.00
Pack Size: 25g
Purity: 98%
in stock
$326.00 $228.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA000OXL
Chemical Name: L-Homocitrulline
CAS Number: 1190-49-4
Molecular Formula: C7H15N3O3
Molecular Weight: 189.2123
MDL Number: MFCD00038143
SMILES: NC(=O)NCCCC[C@@H](C(=O)O)N
Properties
Complexity: 184  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 1  
Heavy Atom Count: 13  
Hydrogen Bond Acceptor Count: 4  
Hydrogen Bond Donor Count: 4  
Rotatable Bond Count: 6  
XLogP3: -3.9  
Literature fold

Title: Simultaneous measurement of protein-bound 3-chlorotyrosine and homocitrulline by LC-MS/MS after hydrolysis assisted by microwave: application to the study of myeloperoxidase activity during hemodialysis.

Journal: Talanta20120915

Title: Impact of carbamylation and glycation of collagen type I on migration of HT1080 human fibrosarcoma cells.

Journal: International journal of oncology20120601

Title: Quantification of plasma homocitrulline using hydrophilic interaction liquid chromatography (HILIC) coupled to tandem mass spectrometry.

Journal: Analytical and bioanalytical chemistry20120201

Title: Potential of Novel EPO Derivatives in Limb Ischemia.

Journal: Cardiology research and practice20120101

Title: Impact of premature birth and critical illness on neonatal range of plasma amino acid concentrations determined by LC-MS/MS.

Journal: Molecular genetics and metabolism20111201

Title: New device measures atmospheric isocyanic acid.

Journal: Environmental health perspectives20110801

Title: Dual mechanism of brain damage induced in vivo by the major metabolites accumulating in hyperornithinemia-hyperammonemia-homocitrullinuria syndrome.

Journal: Brain research20110119

Title: Myeloperoxidase-derived oxidation: mechanisms of biological damage and its prevention.

Journal: Journal of clinical biochemistry and nutrition20110101

Title: Biological responses to perfluorododecanoic acid exposure in rat kidneys as determined by integrated proteomic and metabonomic studies.

Journal: PloS one20110101

Title: Erythropoietin: recent developments in the treatment of spinal cord injury.

Journal: Neurology research international20110101

Title: Anticitrulline antibodies can be caused by homocitrulline-containing proteins in rabbits.

Journal: Arthritis and rheumatism20101101

Title: Carbamylation-dependent activation of T cells: a novel mechanism in the pathogenesis of autoimmune arthritis.

Journal: Journal of immunology (Baltimore, Md. : 1950)20100615

Title: In vitro inhibition of low density lipoprotein carbamylation by vitamins, as an ameliorating atherosclerotic risk in uremic patients.

Journal: Scandinavian journal of clinical and laboratory investigation20100401

Title: Evidence that the major metabolites accumulating in hyperornithinemia-hyperammonemia-homocitrullinuria syndrome induce oxidative stress in brain of young rats.

Journal: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience20091101

Title: Experimental evidence that ornithine and homocitrulline disrupt energy metabolism in brain of young rats.

Journal: Brain research20090929

Title: Retinal degeneration.

Journal: Ophthalmology20090801

Title: Identification of novel mutations in the SLC25A15 gene in hyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome: a clinical, molecular, and functional study.

Journal: Human mutation20090501

Title: Phenotypic variability among patients with hyperornithinaemia-hyperammonaemia-homocitrullinuria syndrome homozygous for the delF188 mutation in SLC25A15.

Journal: Journal of medical genetics20081101

Title: 'O', erythropoietin carbamoylation versus carbamylation.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association20080901

Title: Hyperornithinemia-hyperammonemia-homocitrullinuria syndrome (HHH) presenting with acute fulminant hepatic failure.

Journal: Journal of pediatric gastroenterology and nutrition20080301

Title: Hyperornithinemia-hyperammonemia-homocitrullinuria syndrome with stroke-like imaging presentation: clinical, biochemical and molecular analysis.

Journal: Journal of the neurological sciences20080115

Title: Acetyl-lysine analog peptides as mechanistic probes of protein deacetylases.

Journal: The Journal of biological chemistry20071221

Title: Protein carbamylation links inflammation, smoking, uremia and atherogenesis.

Journal: Nature medicine20071001

Title: 'Multipurpose oxidase' in atherogenesis.

Journal: Nature medicine20071001

Title: Determination of homocitrulline in urine of patients with HHH syndrome by liquid chromatography tandem mass spectrometry.

Journal: Analytical and bioanalytical chemistry20061201

Title: HHH syndrome (hyperornithinaemia, hyperammonaemia, homocitrullinuria), with fulminant hepatitis-like presentation.

Journal: Journal of inherited metabolic disease20060201

Title: Carbamylated low-density lipoprotein induces death of endothelial cells: a link to atherosclerosis in patients with kidney disease.

Journal: Kidney international20050701

Title: Hyperornithinemia, hyperammonemia, and homocitrullinuria syndrome with evidence of mitochondrial dysfunction due to a novel SLC25A15 (ORNT1) gene mutation in a Palestinian family.

Journal: Journal of the neurological sciences20040315

Title: The mitochondrial ornithine transporter. Bacterial expression, reconstitution, functional characterization, and tissue distribution of two human isoforms.

Journal: The Journal of biological chemistry20030829

Title: Cloning and characterization of human ORNT2: a second mitochondrial ornithine transporter that can rescue a defective ORNT1 in patients with the hyperornithinemia-hyperammonemia-homocitrullinuria syndrome, a urea cycle disorder.

Journal: Molecular genetics and metabolism20030801

Title: [Structure-function relationships of mitochondrial transporters].

Journal: Nihon rinsho. Japanese journal of clinical medicine20020401

Title: [Mitochondrial ornithine transporter deficiency].

Journal: Nihon rinsho. Japanese journal of clinical medicine20020401

Title: Seven novel mutations in the ORNT1 gene (SLC25A15) in patients with hyperornithinemia, hyperammonemia, and homocitrullinuria syndrome.

Journal: Human mutation20011101

Title: Clinical and molecular findings in hyperornithinemia-hyperammonemia-homocitrullinuria syndrome.

Journal: Neurology20010911

Title: HHH syndrome associated with callosal agenesis and disordered neuronal migration.

Journal: Developmental medicine and child neurology20010601

Title: Carbamoylation of glomerular and tubular proteins in patients with kidney failure: a potential mechanism of ongoing renal damage.

Journal: Swiss medical weekly20010324

Title: [Hyperornithinemia-hyperammonemia-homocitrullinuria syndrome].

Journal: Ryoikibetsu shokogun shirizu20010101

Title: Conscientious metabolic monitoring on a patient with hyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome undergoing anaesthesia.

Journal: Amino acids20010101

Title: Kato T, et al. Homocitrullinuria and homoargininuria in lysinuric protein intolerance. J Inherit Metab Dis. 1989;12(2):157-61.

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