127-63-9,MFCD00007548
Catalog No.:AA000WFX

127-63-9 | Diphenyl sulfone

Pack Size
Purity
Availability
Price(USD)
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25g
>99%(GC)
in stock  
$24.00   $17.00
- +
100g
>99%(GC)
in stock  
$43.00   $30.00
- +
500g
>99%(GC)
in stock  
$86.00   $60.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA000WFX
Chemical Name:
Diphenyl sulfone
CAS Number:
127-63-9
Molecular Formula:
C12H10O2S
Molecular Weight:
218.2716
MDL Number:
MFCD00007548
SMILES:
O=S(=O)(c1ccccc1)c1ccccc1
Properties
Properties
 
BP:
379°C at 760 mmHg  
Form:
Solid  
MP:
123-129 °C  
Refractive Index:
1.5200 (estimate)  
Solubility:
>14mg/l  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
253  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
15  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
0  
Isotope Atom Count:
0  
Rotatable Bond Count:
2  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
2.4  

Literature

Title: New heterocyclic compounds from 1,2,4-triazole and 1,3,4-thiadiazole class bearing diphenylsulfone moieties. Synthesis, characterization and antimicrobial activity evaluation.

Journal: European journal of medicinal chemistry 20120301

Title: Discovery of 7-arylsulfonyl-1,2,3,4, 4a,9a-hexahydro-benzo[4,5]furo[2,3-c]pyridines: identification of a potent and selective 5-HT₆ receptor antagonist showing activity in rat social recognition test.

Journal: Bioorganic & medicinal chemistry letters 20120201

Title: HiTSEE KNIME: a visualization tool for hit selection and analysis in high-throughput screening experiments for the KNIME platform.

Journal: BMC bioinformatics 20120101

Title: Comparison of migration from polyethersulphone and polycarbonate baby bottles.

Journal: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20111201

Title: Bismuth heterocycles based on a diphenyl sulfone scaffold: synthesis and substituent effect on the antifungal activity against Saccharomyces cerevisiae.

Journal: European journal of medicinal chemistry 20110201

Title: Confab - Systematic generation of diverse low-energy conformers.

Journal: Journal of cheminformatics 20110101

Title: Synthesis of Diarylpyrazoles Containing a Phenylsulphone or Carbonitrile Moiety and their Chalcones as Possible Anti-Inflammatory Agents.

Journal: Scientia pharmaceutica 20110101

Title: Synthesis and antimicrobial evaluation of some fused heterocyclic [1,2,4]triazolo[3,4-b][1,3,4]thiadiazole derivatives.

Journal: European journal of medicinal chemistry 20101201

Title: Environmental and human health risk assessment of organic micro-pollutants occurring in a Spanish marine fish farm.

Journal: Environmental pollution (Barking, Essex : 1987) 20100501

Title: Identification of phenylsulfone-substituted quinoxaline (WYE-672) as a tissue selective liver X-receptor (LXR) agonist.

Journal: Journal of medicinal chemistry 20100422

Title: Modulation of Wnt signaling through inhibition of secreted frizzled-related protein I (sFRP-1) with N-substituted piperidinyl diphenylsulfonyl sulfonamides: part II.

Journal: Bioorganic & medicinal chemistry 20100101

Title: Benzhydryl phenyl sulfone.

Journal: Acta crystallographica. Section E, Structure reports online 20091201

Title: Synthesis, characterization and evaluation of antibacterial activity of some thiazolo[3,2-b][1,2,4]triazole incorporating diphenylsulfone moieties.

Journal: European journal of medicinal chemistry 20091101

Title: Synthesis, characterization and antibacterial activity of some triazole Mannich bases carrying diphenylsulfone moieties.

Journal: European journal of medicinal chemistry 20090701

Title: Polystyrene bound oxidovanadium(IV) and dioxidovanadium(V) complexes of histamine derived ligand for the oxidation of methyl phenyl sulfide, diphenyl sulfide and benzoin.

Journal: Dalton transactions (Cambridge, England : 2003) 20090328

Title: Application of passive sampling devices for screening of micro-pollutants in marine aquaculture using LC-MS/MS.

Journal: Talanta 20090215

Title: 4-Chloro-N-(4-chloro-phenyl-sulfon-yl)-N-(3-oxo-2,3-dihydro-1,2-benzisothia-zol-2-yl)benzene-sulfonamide.

Journal: Acta crystallographica. Section E, Structure reports online 20090201

Title: Stereoselective synthesis of a C-linked neuraminic acid disaccharide: potential building block for the synthesis of C-analogues of polysialic acids.

Journal: The Journal of organic chemistry 20081205

Title: Hydride affinities of cumulated, isolated, and conjugated dienes in acetonitrile.

Journal: The Journal of organic chemistry 20081107

Title: 3,5-Difluoro-phenyl phenyl sulfone.

Journal: Acta crystallographica. Section E, Structure reports online 20081101

Title: Bis(3-nitro-phen-yl) sulfone.

Journal: Acta crystallographica. Section E, Structure reports online 20080801

Title: Toward prediction of alkane/water partition coefficients.

Journal: Journal of medicinal chemistry 20080710

Title: Bis[4-(2-hydroxy-ethyl-amino)phen-yl] sulfone.

Journal: Acta crystallographica. Section E, Structure reports online 20080101

Title: Chlorodifluoromethyl phenyl sulfone: a novel non-ozone-depleting substance-based difluorocarbene reagent for O- and N-difluoromethylations.

Journal: Chemical communications (Cambridge, England) 20071228

Title: A reductive cyclization approach to attenol A.

Journal: The Journal of organic chemistry 20070330

Title: Use of simple docking methods to screen a virtual library for heteroactivators of cytochrome P450 2C9.

Journal: Journal of medicinal chemistry 20070322

Title: 5-Heteroatom substituted pyrazoles as canine COX-2 inhibitors. Part III: molecular modeling studies on binding contribution of 1-(5-methylsulfonyl)pyrid-2-yl and 4-nitrile.

Journal: Bioorganic & medicinal chemistry letters 20070215

Title: Polysulfone-ZrO(2) surface interactions. The influence on formation, morphology and properties of zirfon-membranes.

Journal: The journal of physical chemistry. B 20060413

Title: Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).

Journal: Journal of medicinal chemistry 20050505

Title: Cytotoxic chromenes from Myriactis humilis.

Journal: Planta medica 20050401

Title: Determination of the sulphoxides and sulphones of three simple sulphides in rat urine: effects of phenobarbitone, beta-naphthoflavone and methimazole.

Journal: Biomedical chromatography : BMC 20050101

Title: Antifungal activity of organobismuth compounds against the yeast Saccharomyces cerevisiae: structure-activity relationship.

Journal: Journal of inorganic biochemistry 20040301

Title: [A case of Hansen's disease seen in an Indonesian resident, and tracing of the patient after coming back to Indonesia].

Journal: Nihon Hansenbyo Gakkai zasshi = Japanese journal of leprosy : official organ of the Japanese Leprosy Association 20030801

Title: HPLC analysis of 4-chlorophenyl methyl sulphide and diphenyl sulphide and their corresponding sulphoxides and sulphones in rat liver microsomes.

Journal: Journal of pharmaceutical and biomedical analysis 20020101

Title: A simple enantioselective synthesis of serratenediol.

Journal: Organic letters 20011004

Title: Unique anti-human immunodeficiency virus activities of the nonnucleoside reverse transcriptase inhibitors calanolide A, costatolide, and dihydrocostatolide.

Journal: Antimicrobial agents and chemotherapy 19990801

Title: Highly potent oxathiin carboxanilide derivatives with efficacy against nonnucleoside reverse transcriptase inhibitor-resistant human immunodeficiency virus isolates.

Journal: Antimicrobial agents and chemotherapy 19970401

Title: Biological and biochemical anti-human immunodeficiency virus activity of UC 38, a new non-nucleoside reverse transcriptase inhibitor.

Journal: The Journal of pharmacology and experimental therapeutics 19960101

Title: Characteristics of a group of nonnucleoside reverse transcriptase inhibitors with structural diversity and potent anti-human immunodeficiency virus activity.

Journal: Leukemia 19951001

Title: Resistance to 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine derivatives is generated by mutations at multiple sites in the HIV-1 reverse transcriptase.

Journal: Virology 19950620

Title: Diarylsulfones, a new chemical class of nonnucleoside antiviral inhibitors of human immunodeficiency virus type 1 reverse transcriptase.

Journal: Antimicrobial agents and chemotherapy 19930401

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SDS
Tags:127-63-9 Molecular Formula|127-63-9 MDL|127-63-9 SMILES|127-63-9 Diphenyl sulfone
Catalog No.: AA000WFX
127-63-9,MFCD00007548
127-63-9 | Diphenyl sulfone
Pack Size: 25g
Purity: >99%(GC)
in stock
$24.00 $17.00
Pack Size: 100g
Purity: >99%(GC)
in stock
$43.00 $30.00
Pack Size: 500g
Purity: >99%(GC)
in stock
$86.00 $60.00
Quantity
- +
Add to Card
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bulk Quotation Request
Technical Information
Catalog Number: AA000WFX
Chemical Name: Diphenyl sulfone
CAS Number: 127-63-9
Molecular Formula: C12H10O2S
Molecular Weight: 218.2716
MDL Number: MFCD00007548
SMILES: O=S(=O)(c1ccccc1)c1ccccc1
Properties
BP: 379°C at 760 mmHg  
Form: Solid  
MP: 123-129 °C  
Refractive Index: 1.5200 (estimate)  
Solubility: >14mg/l  
Storage: Keep in dry area;Room Temperature;  
Complexity: 253  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 15  
Hydrogen Bond Acceptor Count: 2  
Hydrogen Bond Donor Count: 0  
Isotope Atom Count: 0  
Rotatable Bond Count: 2  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 2.4  
Literature fold

Title: New heterocyclic compounds from 1,2,4-triazole and 1,3,4-thiadiazole class bearing diphenylsulfone moieties. Synthesis, characterization and antimicrobial activity evaluation.

Journal: European journal of medicinal chemistry20120301

Title: Discovery of 7-arylsulfonyl-1,2,3,4, 4a,9a-hexahydro-benzo[4,5]furo[2,3-c]pyridines: identification of a potent and selective 5-HT₆ receptor antagonist showing activity in rat social recognition test.

Journal: Bioorganic & medicinal chemistry letters20120201

Title: HiTSEE KNIME: a visualization tool for hit selection and analysis in high-throughput screening experiments for the KNIME platform.

Journal: BMC bioinformatics20120101

Title: Comparison of migration from polyethersulphone and polycarbonate baby bottles.

Journal: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment20111201

Title: Bismuth heterocycles based on a diphenyl sulfone scaffold: synthesis and substituent effect on the antifungal activity against Saccharomyces cerevisiae.

Journal: European journal of medicinal chemistry20110201

Title: Confab - Systematic generation of diverse low-energy conformers.

Journal: Journal of cheminformatics20110101

Title: Synthesis of Diarylpyrazoles Containing a Phenylsulphone or Carbonitrile Moiety and their Chalcones as Possible Anti-Inflammatory Agents.

Journal: Scientia pharmaceutica20110101

Title: Synthesis and antimicrobial evaluation of some fused heterocyclic [1,2,4]triazolo[3,4-b][1,3,4]thiadiazole derivatives.

Journal: European journal of medicinal chemistry20101201

Title: Environmental and human health risk assessment of organic micro-pollutants occurring in a Spanish marine fish farm.

Journal: Environmental pollution (Barking, Essex : 1987)20100501

Title: Identification of phenylsulfone-substituted quinoxaline (WYE-672) as a tissue selective liver X-receptor (LXR) agonist.

Journal: Journal of medicinal chemistry20100422

Title: Modulation of Wnt signaling through inhibition of secreted frizzled-related protein I (sFRP-1) with N-substituted piperidinyl diphenylsulfonyl sulfonamides: part II.

Journal: Bioorganic & medicinal chemistry20100101

Title: Benzhydryl phenyl sulfone.

Journal: Acta crystallographica. Section E, Structure reports online20091201

Title: Synthesis, characterization and evaluation of antibacterial activity of some thiazolo[3,2-b][1,2,4]triazole incorporating diphenylsulfone moieties.

Journal: European journal of medicinal chemistry20091101

Title: Synthesis, characterization and antibacterial activity of some triazole Mannich bases carrying diphenylsulfone moieties.

Journal: European journal of medicinal chemistry20090701

Title: Polystyrene bound oxidovanadium(IV) and dioxidovanadium(V) complexes of histamine derived ligand for the oxidation of methyl phenyl sulfide, diphenyl sulfide and benzoin.

Journal: Dalton transactions (Cambridge, England : 2003)20090328

Title: Application of passive sampling devices for screening of micro-pollutants in marine aquaculture using LC-MS/MS.

Journal: Talanta20090215

Title: 4-Chloro-N-(4-chloro-phenyl-sulfon-yl)-N-(3-oxo-2,3-dihydro-1,2-benzisothia-zol-2-yl)benzene-sulfonamide.

Journal: Acta crystallographica. Section E, Structure reports online20090201

Title: Stereoselective synthesis of a C-linked neuraminic acid disaccharide: potential building block for the synthesis of C-analogues of polysialic acids.

Journal: The Journal of organic chemistry20081205

Title: Hydride affinities of cumulated, isolated, and conjugated dienes in acetonitrile.

Journal: The Journal of organic chemistry20081107

Title: 3,5-Difluoro-phenyl phenyl sulfone.

Journal: Acta crystallographica. Section E, Structure reports online20081101

Title: Bis(3-nitro-phen-yl) sulfone.

Journal: Acta crystallographica. Section E, Structure reports online20080801

Title: Toward prediction of alkane/water partition coefficients.

Journal: Journal of medicinal chemistry20080710

Title: Bis[4-(2-hydroxy-ethyl-amino)phen-yl] sulfone.

Journal: Acta crystallographica. Section E, Structure reports online20080101

Title: Chlorodifluoromethyl phenyl sulfone: a novel non-ozone-depleting substance-based difluorocarbene reagent for O- and N-difluoromethylations.

Journal: Chemical communications (Cambridge, England)20071228

Title: A reductive cyclization approach to attenol A.

Journal: The Journal of organic chemistry20070330

Title: Use of simple docking methods to screen a virtual library for heteroactivators of cytochrome P450 2C9.

Journal: Journal of medicinal chemistry20070322

Title: 5-Heteroatom substituted pyrazoles as canine COX-2 inhibitors. Part III: molecular modeling studies on binding contribution of 1-(5-methylsulfonyl)pyrid-2-yl and 4-nitrile.

Journal: Bioorganic & medicinal chemistry letters20070215

Title: Polysulfone-ZrO(2) surface interactions. The influence on formation, morphology and properties of zirfon-membranes.

Journal: The journal of physical chemistry. B20060413

Title: Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).

Journal: Journal of medicinal chemistry20050505

Title: Cytotoxic chromenes from Myriactis humilis.

Journal: Planta medica20050401

Title: Determination of the sulphoxides and sulphones of three simple sulphides in rat urine: effects of phenobarbitone, beta-naphthoflavone and methimazole.

Journal: Biomedical chromatography : BMC20050101

Title: Antifungal activity of organobismuth compounds against the yeast Saccharomyces cerevisiae: structure-activity relationship.

Journal: Journal of inorganic biochemistry20040301

Title: [A case of Hansen's disease seen in an Indonesian resident, and tracing of the patient after coming back to Indonesia].

Journal: Nihon Hansenbyo Gakkai zasshi = Japanese journal of leprosy : official organ of the Japanese Leprosy Association20030801

Title: HPLC analysis of 4-chlorophenyl methyl sulphide and diphenyl sulphide and their corresponding sulphoxides and sulphones in rat liver microsomes.

Journal: Journal of pharmaceutical and biomedical analysis20020101

Title: A simple enantioselective synthesis of serratenediol.

Journal: Organic letters20011004

Title: Unique anti-human immunodeficiency virus activities of the nonnucleoside reverse transcriptase inhibitors calanolide A, costatolide, and dihydrocostatolide.

Journal: Antimicrobial agents and chemotherapy19990801

Title: Highly potent oxathiin carboxanilide derivatives with efficacy against nonnucleoside reverse transcriptase inhibitor-resistant human immunodeficiency virus isolates.

Journal: Antimicrobial agents and chemotherapy19970401

Title: Biological and biochemical anti-human immunodeficiency virus activity of UC 38, a new non-nucleoside reverse transcriptase inhibitor.

Journal: The Journal of pharmacology and experimental therapeutics19960101

Title: Characteristics of a group of nonnucleoside reverse transcriptase inhibitors with structural diversity and potent anti-human immunodeficiency virus activity.

Journal: Leukemia19951001

Title: Resistance to 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine derivatives is generated by mutations at multiple sites in the HIV-1 reverse transcriptase.

Journal: Virology19950620

Title: Diarylsulfones, a new chemical class of nonnucleoside antiviral inhibitors of human immunodeficiency virus type 1 reverse transcriptase.

Journal: Antimicrobial agents and chemotherapy19930401

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