Title: Discriminating between adaptive and carcinogenic liver hypertrophy in rat studies using logistic ridge regression analysis of toxicogenomic data: The mode of action and predictive models.
Journal: Toxicology and applied pharmacology 20170301
Title: [Toxic effects of trimethadione on zebrafish early development].
Journal: Yi chuan = Hereditas 20120901
Title: Update on endoscopic management of main pancreatic duct stones in chronic calcific pancreatitis.
Journal: The Korean journal of internal medicine 20120301
Title: Induction of specific immunotherapy with hymenoptera venoms using ultrarush regimen in children: safety and tolerance.
Journal: Journal of allergy 20120101
Title: Genetic polymorphisms in CYP2E1: association with schizophrenia susceptibility and risperidone response in the Chinese Han population.
Journal: PloS one 20120101
Title: Short-term long chain omega3 diet protects from neuroinflammatory processes and memory impairment in aged mice.
Journal: PloS one 20120101
Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Journal: PLoS computational biology 20111201
Title: Treatment of myasthenia gravis based on its immunopathogenesis.
Journal: Journal of clinical neurology (Seoul, Korea) 20111201
Title: Co-variation in frequency and severity of cardiovascular and skeletal defects in Sprague-Dawley rats after maternal administration of dimethadione, the N-demethylated metabolite of trimethadione.
Journal: Birth defects research. Part B, Developmental and reproductive toxicology 20110601
Title: Zebrafish (Danio rerio) embryos as a model for testing proteratogens.
Journal: Toxicology 20110315
Title: Cognitive and emotional alterations are related to hippocampal inflammation in a mouse model of metabolic syndrome.
Journal: PloS one 20110101
Title: Studies of properties of 'Pain Networks' as predictors of targets of stimulation for treatment of pain.
Journal: Frontiers in integrative neuroscience 20110101
Title: Intrauterine growth retardation and nonalcoholic Fatty liver disease in children.
Journal: International journal of endocrinology 20110101
Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201
Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Journal: Bioorganic & medicinal chemistry letters 20101101
Title: Lamotrigine extends lifespan but compromises health span in Drosophila melanogaster.
Journal: Biogerontology 20100201
Title: Allyl isothiocyanate that induces GST and UGT expression confers oxidative stress resistance on C. elegans, as demonstrated by nematode biosensor.
Journal: PloS one 20100101
Title: Neuroprotective effects of blockers for T-type calcium channels.
Journal: Molecular neurodegeneration 20090101
Title: Treatment of Lennox-Gastaut syndrome: overview and recent findings.
Journal: Neuropsychiatric disease and treatment 20081201
Title: Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Journal: Journal of medicinal chemistry 20081113
Title: The anticonvulsant ethosuximide disrupts sensory function to extend C. elegans lifespan.
Journal: PLoS genetics 20081001
Title: Valproic acid extends Caenorhabditis elegans lifespan.
Journal: Aging cell 20080601
Title: Design and synthesis of 6-amino-1,4-oxazepane-3,5-dione derivatives as novel broad spectrum anticonvulsants.
Journal: Bioorganic & medicinal chemistry letters 20080601
Title: Etiology of congenital dislocation of the hip : Carl E. Badgley MD (1893-1973). The 11th president of the AAOS 1942.
Journal: Clinical orthopaedics and related research 20080101
Title: Effect of optical flow versus attentional strategy on gait in Parkinson's Disease: a study with a portable optical stimulating device.
Journal: Journal of neuroengineering and rehabilitation 20080101
Title: Prophylactic and therapeutic functions of T-type calcium blockers against noise-induced hearing loss.
Journal: Hearing research 20070401
Title: Classification and diagnosis of ear malformations.
Journal: GMS current topics in otorhinolaryngology, head and neck surgery 20070101
Title: The ethics of excluding women who become pregnant while participating in clinical trials of anti-epileptic medications.
Journal: Seizure 20061201
Title: Pharmacology of delayed aging and extended lifespan of Caenorhabditis elegans.
Journal: Experimental gerontology 20061001
Title: Education and imaging. Hepatobiliary and pancreatic: oral therapy for pancreatic duct stones.
Journal: Journal of gastroenterology and hepatology 20060901
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: Effects of anticonvulsant drugs on life span.
Journal: Archives of neurology 20060401
Title: The history of barbiturates a century after their clinical introduction.
Journal: Neuropsychiatric disease and treatment 20051201
Title: The antihyperalgesic effects of the T-type calcium channel blockers ethosuximide, trimethadione, and mibefradil.
Journal: European journal of pharmacology 20051003
Title: Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
Journal: Journal of pharmaceutical sciences 20050701
Title: Oral litholysis therapy for endoscopically unretrievable obstructive pancreatic stones.
Journal: Pancreas 20050501
Title: Adulteration of South African traditional herbal remedies.
Journal: Therapeutic drug monitoring 20050201
Title: Anticonvulsant medications extend worm life-span.
Journal: Science (New York, N.Y.) 20050114
Title: Postnatal closure of membranous ventricular septal defects in Sprague-Dawley rat pups after maternal exposure with trimethadione.
Journal: Birth defects research. Part B, Developmental and reproductive toxicology 20040601
Title: Involvement of cytochrome P450 2C9, 2E1 and 3A4 in trimethadione N-demethylation in human microsomes.
Journal: Journal of clinical pharmacy and therapeutics 20031201
Title: Embryonic arrhythmia by inhibition of HERG channels: a common hypoxia-related teratogenic mechanism for antiepileptic drugs?
Journal: Epilepsia 20020501
Title: Determination of trimetazidine HCl by adsorptive stripping square-wave voltammetry at a glassy carbon electrode.
Journal: Journal of pharmaceutical and biomedical analysis 20020101
Title: The clinical importance of the trimethadione tolerance test as a method for quantitative assessment of hepatic functional reserve in patients with biliary atresia.
Journal: Journal of clinical pharmacy and therapeutics 20011201
Title: Pharmacological characterization of the 6 Hz psychomotor seizure model of partial epilepsy.
Journal: Epilepsy research 20011201
Title: [Fetal trimethadione syndrome].
Journal: Ryoikibetsu shokogun shirizu 20010101
Title: Anticonvulsants for soman-induced seizure activity.
Journal: Journal of biomedical science 19990101
Title: Trimethadione N-demethylation by rat liver CYP2E1 in vitro.
Journal: Research communications in molecular pathology and pharmacology 19960701
Title: Characterization of the antiabsence effects of SCH 50911, a GABA-B receptor antagonist, in the lethargic mouse, gamma-hydroxybutyrate, and pentylenetetrazole models.
Journal: The Journal of pharmacology and experimental therapeutics 19950901
Title: Dissolution of pancreatic stones by oral trimethadione in patients with chronic calcific pancreatitis.
Journal: Journal of gastroenterology and hepatology 19940101
Title: Effects of the oxazolidinedione anticonvulsants trimethadione and dimethadione and the barbiturate homolog 5,5-dimethylbarbituric acid on N-nitrosodiethylamine-initiated renal and hepatic carcinogenesis in the F344/NCr rat.
Journal: Archives of toxicology 19920101
Title: Anticonvulsive and convulsive effects of lidocaine: comparison with those of phenytoin, and implications for mechanism of action concepts.
Journal: Neurological research 19880901
Title: Effects of antiepileptic drugs on absence-like and tonic seizures in the spontaneously epileptic rat, a double mutant rat.
Journal: Epilepsia 19880101
Title: Only certain antiepileptic drugs prevent seizures induced by pilocarpine.
Journal: Brain research 19870701
Title: Use of ethosuximide and valproate in the treatment of epilepsy.
Journal: Neurologic clinics 19860801
Title: Antiepileptic drug evaluation in a new animal model: spontaneous petit mal epilepsy in the rat.
Journal: Arzneimittel-Forschung 19850101
Title: Fetal anticonvulsant syndrome in rats: effects on postnatal behavior and brain amino acid content.
Journal: Neurobehavioral toxicology and teratology 19850101
Title: A model of chronic spontaneous petit mal-like seizures in the rat: comparison with pentylenetetrazol-induced seizures.
Journal: Epilepsia 19840601
Title: Fetal anticonvulsant syndrome in rats: dose- and period-response relationships of prenatal diphenylhydantoin, trimethadione and phenobarbital exposure on the structural and functional development of the offspring.
Journal: The Journal of pharmacology and experimental therapeutics 19831101
Title: Comparison of the actions of trimethadione and chlordiazepoxide in animal models of anxiety and benzodiazepine receptor binding.
Journal: Neuropharmacology 19821101
Title: Anticonvulsants specific for petit mal antagonize epileptogenic effect of leucine enkephalin.
Journal: Science (New York, N.Y.) 19801128
Title: Troxidone (trimethadione) embryopathy: case report with reveiw of the literature.
Journal: Clinical and experimental neurology 19790101
Title: Phenotypic malformations in association with maternal trimethadione therapy.
Journal: The Journal of pediatrics 19780201
Title: Anti-convulsant effect of phthalazino-2,3b-phthalazine-5(14H),12(7h)-dione (L-5418). I. Behavioral effect.
Journal: Japanese journal of pharmacology 19780201
Title: The fetal trimethadione syndrome: report of an additional family and further delineation of this syndrome.
Journal: American journal of diseases of children (1960) 19771201
Title: [Quantitative analysis of conditional-optimal doses of succilep and trimetin in the treatment of children and adolescents with minor forms of epilepsy].
Journal: Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952) 19770101
Title: Measurement of anticonvulsant activity in the Papio papio model of epilepsy.
Journal: Federation proceedings 19760901
Title: Cardiac defects in children of mothers receiving anticonvulsant therapy during pregnancy.
Journal: The Journal of pediatrics 19760801
Title: Di-n-propylacetic acid--profile of anticonvulsant activity in mice.
Journal: Arzneimittel-Forschung 19760201
Title: The fetal trimethadione syndrome.
Journal: The Journal of pediatrics 19750801
Title: Fetal anomalies following maternal trimethadione ingestion.
Journal: The Journal of pediatrics 19730501
Title: Trimethadione (Tridione)-induced nephrotic syndrome. A report of a case with unique ultrastructural renal pathology.
Journal: The American journal of medicine 19730201
Title: Possible teratogenicity of trimethadione and paramethadione.
Journal: Lancet (London, England) 19700801
Title: Pharmacologic interactions of albutoin with other anticonvulsant drugs.
Journal: The Journal of pharmacology and experimental therapeutics 19700801
Title: Myasthenia gravis syndrome associated with trimethadione.
Journal: JAMA 19700629
Title: Successful therapy of trimethadione nephrosis with prednisone and cyclophosphamide. Report of a case.
Journal: The Journal of pediatrics 19670801
Title: Nephrotic syndrome caused by probenecid.
Journal: JAMA 19670102
Title: Pastore V, et, al. Synthesis and anticonvulsant activity of bioisosteres of trimethadione, N-derivative-1,2,3-oxathiazolidine-4-one-2,2-dioxides from α-hydroxyamides. Bioorg Med Chem. 2013 Feb 15;21(4):841-6.
Title: Barton ME, et, al. The antihyperalgesic effects of the T-type calcium channel blockers ethosuximide, trimethadione, and mibefradil. Eur J Pharmacol. 2005 Oct 3;521(1-3):79-85.
