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144927-57-1,MFCD11518913
Catalog No.:AA001KAO

144927-57-1 | Ethyl 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carboxylate

Pack Size
Purity
Availability
Price(USD)
Quantity
  
100mg
97%
in stock  
$9.00   $7.00
- +
1g
98%
in stock  
$75.00   $53.00
- +
5g
98%
in stock  
$314.00   $220.00
- +
10g
98%
in stock  
$617.00   $432.00
- +
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA001KAO
Chemical Name:
Ethyl 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carboxylate
CAS Number:
144927-57-1
Molecular Formula:
C9H8ClN3O2
Molecular Weight:
225.6317
MDL Number:
MFCD11518913
SMILES:
CCOC(=O)c1c[nH]c2c1c(Cl)ncn2
Properties
Computed Properties
 
Complexity:
252  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
15  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
3  
XLogP3:
1.8  

Upstream Synthesis Route

[1]Patent:EP2390254,2011,A1,.Locationinpatent:Page/Pagecolumn67

[2]JournalofMedicinalChemistry,2000,vol.43,#15,p.2883-2893

[3]Patent:WO2013/85802,2013,A1,.Locationinpatent:Page/Pagecolumn49-50

[1]Patent:EP2390254,2011,A1,

[2]Patent:WO2013/85802,2013,A1,

Downstream Synthesis Route

[1]Patent:EP2390254,2011,A1.Locationinpatent:Page/Pagecolumn67

[2]JournalofMedicinalChemistry,2000,vol.43,p.2883-2893

[3]Patent:WO2013/85802,2013,A1.Locationinpatent:Page/Pagecolumn49-50

[1]JournalofMedicinalChemistry,2000,vol.43,p.2883-2893

144927-57-1   
4-amino-7-(3,4-dihydroxy-5-methyl-tetrahydro-furan-2-yl)-7<i>H</i>-pyrrolo2,3-<i>d</i>pyrimidine-5-carboxylicacidethylester 

[1]JournalofMedicinalChemistry,2000,vol.43,p.2883-2893

144927-57-1   
4-amino-7-(2,2,6-trimethyl-tetrahydro-furo3,4-<i>d</i>1,3dioxol-4-yl)-7<i>H</i>-pyrrolo2,3-<i>d</i>pyrimidine-5-carboxylicacidethylester 

[1]JournalofMedicinalChemistry,2000,vol.43,p.2883-2893

[1]Patent:EP2390254,2011,A1

[2]Patent:WO2013/85802,2013,A1

Literature

Title: Essential biphasic role for JAK3 catalytic activity in IL-2 receptor signaling.

Journal: Nature chemical biology 20160501

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SDS
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Tags:144927-57-1 Molecular Formula|144927-57-1 MDL|144927-57-1 SMILES|144927-57-1 Ethyl 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carboxylate