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145-42-6,MFCD00150132
Catalog No.:AA001KCW

145-42-6 | Monosodium taurocholate

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1g
≥95%
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$46.00   $32.00
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5g
≥95%
in stock  
$166.00   $116.00
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10g
≥95%
in stock  
$285.00   $199.00
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25g
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA001KCW
Chemical Name:
Monosodium taurocholate
CAS Number:
145-42-6
Molecular Formula:
C26H44NNaO7S
Molecular Weight:
537.6848
MDL Number:
MFCD00150132
SMILES:
O[C@@H]1CC[C@]2([C@@H](C1)C[C@H]([C@@H]1[C@@H]2C[C@H](O)[C@]2([C@H]1CC[C@@H]2[C@@H](CCC(=O)NCCS(=O)(=O)[O-])C)C)O)C.[Na+]
Properties
Computed Properties
 
Complexity:
897  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
11  
Heavy Atom Count:
36  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
7  

Literature

Title: Cholestatic pregnancy is associated with reduced VCAM1 expression in vascular endothelial cell of placenta.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20171201

Title: Editor's Highlight: Farnesoid X Receptor Protects Against Low-Dose Carbon Tetrachloride-Induced Liver Injury Through the Taurocholate-JNK Pathway.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20170801

Title: An Intestinal Farnesoid X Receptor-Ceramide Signaling Axis Modulates Hepatic Gluconeogenesis in Mice.

Journal: Diabetes 20170301

Title: Bile Acid-Induced Toxicity in HepaRG Cells Recapitulates the Response in Primary Human Hepatocytes.

Journal: Basic & clinical pharmacology & toxicology 20160201

Title: Inhibition of Human Hepatic Bile Acid Transporters by Tolvaptan and Metabolites: Contributing Factors to Drug-Induced Liver Injury?

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20160101

Title: Taurocholate Induces Cyclooxygenase-2 Expression via the Sphingosine 1-phosphate Receptor 2 in a Human Cholangiocarcinoma Cell Line.

Journal: The Journal of biological chemistry 20151225

Title: Regulation of human hepatic drug transporter activity and expression by diesel exhaust particle extract.

Journal: PloS one 20150101

Title: Different dose-dependent mechanisms are involved in early cyclosporine a-induced cholestatic effects in hepaRG cells.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20140901

Title: In silico identification and in vitro validation of potential cholestatic compounds through 3D ligand-based pharmacophore modeling of BSEP inhibitors.

Journal: Chemical research in toxicology 20140519

Title: Evaluation of serum bile acid profiles as biomarkers of liver injury in rodents.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20140101

Title: SLC10A4 is a protease-activated transporter that transports bile acids.

Journal: Journal of biochemistry 20130701

Title: Identification of multiple binding sites for substrate transport in bovine organic anion transporting polypeptide 1a2.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20130301

Title: Resveratrol suppresses microcirculatory disturbance in a rat model of severe acute pancreatitis.

Journal: Cell biochemistry and biophysics 20130101

Title: Potentiation of anti-angiogenic activity of heparin by blocking the ATIII-interacting pentasaccharide unit and increasing net anionic charge.

Journal: Biomaterials 20121201

Title: Photophysical and photodynamical study of ellipticine: an anticancer drug molecule in bile salt modulated in vitro created liposome.

Journal: Physical chemistry chemical physics : PCCP 20121128

Title: Inhibition of poly(ADP-ribose) polymerase attenuates acute kidney injury in sodium taurocholate-induced acute pancreatitis in rats.

Journal: Pancreas 20121101

Title: NFATc3 regulates trypsinogen activation, neutrophil recruitment, and tissue damage in acute pancreatitis in mice.

Journal: Gastroenterology 20121101

Title: Portal vein cytokines in the early phase of acute experimental oedematous and necrotizing porcine pancreatitis.

Journal: Scandinavian journal of gastroenterology 20121101

Title: Effects of FTY720 and rapamycin on inflammation in taurocholate-induced acute pancreatitis in the rat.

Journal: Pancreas 20121001

Title: Ursodeoxycholic acid stimulates the formation of the bile canalicular network.

Journal: Biochemical pharmacology 20121001

Title: Dissection of the hierarchy and synergism of the bile derived signal on Cryptosporidium parvum excystation and infectivity.

Journal: Parasitology 20121001

Title: Pharmaceutical excipients influence the function of human uptake transporting proteins.

Journal: Molecular pharmaceutics 20120904

Title: In silico identification of potential cholestasis-inducing agents via modeling of Na(+)-dependent taurocholate cotransporting polypeptide substrate specificity.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20120901

Title: Rectal taurocholate increases L cell and insulin secretion, and decreases blood glucose and food intake in obese type 2 diabetic volunteers.

Journal: Diabetologia 20120901

Title: Do opioid receptors play a role in the pathogenesis of the inflammatory response in acute pancreatitis?

Journal: Acta cirurgica brasileira 20120901

Title: Tauro-β-muricholic acid restricts bile acid-induced hepatocellular apoptosis by preserving the mitochondrial membrane potential.

Journal: Biochemical and biophysical research communications 20120810

Title: Infliximab enhances the therapeutic effectiveness of octreotide on acute necrotizing pancreatitis in rat model.

Journal: Pancreas 20120801

Title: Bile stimulates cell surface hydrophobicity, Congo red binding and biofilm formation of Lactobacillus strains.

Journal: FEMS microbiology letters 20120801

Title: Protective effect of transplanted bone marrow-derived mesenchymal stem cells on pancreatitis-associated lung injury in rats.

Journal: Molecular medicine reports 20120801

Title: Acute pancreatitis in aging animals: loss of pancreatitis-associated protein protection?

Journal: World journal of gastroenterology 20120714

Title: Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il10-/- mice.

Journal: Nature 20120705

Title: Microbiology: fat, bile and gut microbes.

Journal: Nature 20120704

Title: Evaluation of N-acetylcysteine treatment in acute pancreatitis-induced lung injury.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20120701

Title: Peroxisome proliferator-activated receptor β/δ agonist GW0742 ameliorates cerulein- and taurocholate-induced acute pancreatitis in mice.

Journal: Surgery 20120701

Title: Therapeutic treatment with ethyl pyruvate attenuates the severity of liver injury in rats with severe acute pancreatitis.

Journal: Pancreas 20120701

Title: Bio-relevant media to assess drug permeability: sodium taurocholate and lecithin combination or crude bile?

Journal: International journal of pharmaceutics 20120615

Title: Hypoglycemic activity and oral bioavailability of insulin-loaded liposomes containing bile salts in rats: the effect of cholate type, particle size and administered dose.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20120601

Title: Tumor vasculature targeting following co-delivery of heparin-taurocholate conjugate and suberoylanilide hydroxamic acid using cationic nanolipoplex.

Journal: Biomaterials 20120601

Title: Improved recovery of Clostridium difficile spores with the incorporation of synthetic taurocholate in cycloserine-cefoxitin-fructose agar (CCFA).

Journal: Pathology 20120601

Title: Structural requirements of bile acid transporters: C-3 and C-7 modifications of steroidal hydroxyl groups.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20120512

Title: In vitro evaluation of intestinal fluoride absorption using different cell models.

Journal: Toxicology letters 20120505

Title: Neutrophil-derived matrix metalloproteinase-9 is a potent activator of trypsinogen in acinar cells in acute pancreatitis.

Journal: Journal of leukocyte biology 20120501

Title: Bile acid malabsorption and SeHCAT: the 'Cinderella' will be going to the Nuclear Medicine Ball!

Journal: Nuclear medicine communications 20120501

Title: Measuring SeHCAT retention: the use of a collimated gamma camera.

Journal: Nuclear medicine communications 20120501

Title: Discovery and structural development of small molecules that enhance transport activity of bile salt export pump mutant associated with progressive familial intrahepatic cholestasis type 2.

Journal: Bioorganic & medicinal chemistry 20120501

Title: Effects of infliximab on bacterial translocation in experimental acute necrotizing pancreatitis.

Journal: The Indian journal of medical research 20120501

Title: Taurine attenuates liver injury by downregulating phosphorylated p38 MAPK of Kupffer cells in rats with severe acute pancreatitis.

Journal: Inflammation 20120401

Title: Autophagy regulation by the nuclear factor κB signal axis in acute pancreatitis.

Journal: Pancreas 20120401

Title: Effects of c-Jun N-terminal kinase signaling pathway on severe acute pancreatitis-associated lung injury.

Journal: Pancreas 20120401

Title: Beneficial effect of hypertonic saline resuscitation in a porcine model of severe acute pancreatitis.

Journal: Pancreas 20120301

Title: Resveratrol ameliorates the deleterious effect of severe acute pancreatitis.

Journal: Cell biochemistry and biophysics 20120301

Title: A high throughput in vitro mrp2 assay to predict in vivo biliary excretion.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20120201

Title: Homo- and hetero-dimeric architecture of the human liver Na⁺-dependent taurocholate co-transporting protein.

Journal: The Biochemical journal 20120201

Title: P-selectin mediates neutrophil rolling and recruitment in acute pancreatitis.

Journal: The British journal of surgery 20120201

Title: Differential inhibitory effect of cyclosporin A and bosentan on taurocholate uptake in human and rat hepatocytes as a function of culturing time.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20120201

Title: Role of heparin on serum VEGF levels and local VEGF contents in reducing the severity of experimental severe acute pancreatitis in rats.

Journal: Scandinavian journal of gastroenterology 20120201

Title: Effects and mechanisms of store-operated calcium channel blockade on hepatic ischemia-reperfusion injury in rats.

Journal: World journal of gastroenterology 20120128

Title: Application of simulated intestinal fluid on the phospholipid vesicle-based drug permeation assay.

Journal: International journal of pharmaceutics 20120117

Title: Bile salt-reinforced alginate-chitosan beads.

Journal: Pharmaceutical development and technology 20120101

Title: Conjugated bile acids activate the sphingosine-1-phosphate receptor 2 in primary rodent hepatocytes.

Journal: Hepatology (Baltimore, Md.) 20120101

Title: Involvement of specific transport system on uptake of lactone form of SN-38 in human intestinal epithelial cell line Caco-2.

Journal: Biological & pharmaceutical bulletin 20120101

Title: Intestinal bacterial translocation and tight junction structure in acute porcine pancreatitis.

Journal: Hepato-gastroenterology 20120101

Title: Spores of Clostridium difficile clinical isolates display a diverse germination response to bile salts.

Journal: PloS one 20120101

Title: Zerumbone attenuates the severity of acute necrotizing pancreatitis and pancreatitis-induced hepatic injury.

Journal: Mediators of inflammation 20120101

Title: Photophysical and photodynamical study of fluoroquinolone drug molecule in bile salt aggregates.

Journal: Photochemistry and photobiology 20120101

Title: Differences in the inflammatory response induced by acute pancreatitis in different white adipose tissue sites in the rat.

Journal: PloS one 20120101

Title: Obese rats exhibit high levels of fat necrosis and isoprostanes in taurocholate-induced acute pancreatitis.

Journal: PloS one 20120101

Title: Cryptosporidium parvum oocyst viability and behaviour of the residual body during the excystation process.

Journal: Parasitology research 20111201

Title: Interaction of bile salts with rat canalicular membrane vesicles: evidence for bile salt resistant microdomains.

Journal: Journal of hepatology 20111201

Title: TLR4 but not TLR2 regulates inflammation and tissue damage in acute pancreatitis induced by retrograde infusion of taurocholate.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20111201

Title: A placental phenotype for intrahepatic cholestasis of pregnancy.

Journal: Placenta 20111201

Title: Bile acid malabsorption investigated by selenium-75-homocholic acid taurine ((75)SeHCAT) scans: causes and treatment responses to cholestyramine in 298 patients with chronic watery diarrhoea.

Journal: European journal of internal medicine 20111201

Title: Interaction of fluvastatin with the liver-specific Na+ -dependent taurocholate cotransporting polypeptide (NTCP).

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20111120

Title: Efflux of bile acids in Lactobacillus reuteri is mediated by ATP.

Journal: Biotechnology letters 20111101

Title: Role of neutrophils in the activation of trypsinogen in severe acute pancreatitis.

Journal: Journal of leukocyte biology 20111101

Title: The solubility-permeability interplay: mechanistic modeling and predictive application of the impact of micellar solubilization on intestinal permeation.

Journal: Molecular pharmaceutics 20111003

Title: Effect of terbium(III) on the binding of aromatic guests with sodium taurocholate aggregates.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20111001

Title: New insights into bile acid malabsorption.

Journal: Current gastroenterology reports 20111001

Title: Measuring SeHCAT retention: a technical note.

Journal: Nuclear medicine communications 20111001

Title: Protective effect of clodronate-containing liposomes on intestinal mucosal injury in rats with severe acute pancreatitis.

Journal: Hepatobiliary & pancreatic diseases international : HBPD INT 20111001

Title: Beads made of cyclodextrin and oil for the oral delivery of lipophilic drugs: in vitro studies in simulated gastro-intestinal fluids.

Journal: International journal of pharmaceutics 20110920

Title: Inhibition of iNOS reduces the therapeutic effects of ozone in acute necrotizing pancreatitis: an in vivo animal study.

Journal: Scandinavian journal of clinical and laboratory investigation 20110901

Title: Interactions between organic anions on multiple transporters in Caco-2 cells.

Journal: Journal of pharmaceutical sciences 20110901

Title: Culture period-dependent changes in the uptake of transporter substrates in sandwich-cultured rat and human hepatocytes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20110901

Title: Transient stasis of pancreatic fluid flow together with mild injury of the pancreatic duct cause chronic pancreatitis.

Journal: Digestive diseases and sciences 20110801

Title: Characterization of organic anion-transporting polypeptide (Oatp) 1a1 and 1a4 null mice reveals altered transport function and urinary metabolomic profiles.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20110801

Title: Acidic bile salts modulate the squamous epithelial barrier function by modulating tight junction proteins.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20110801

Title: Determination of OATP-, NTCP- and OCT-mediated substrate uptake activities in individual and pooled batches of cryopreserved human hepatocytes.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20110717

Title: New perspective for the treatment of Alzheimer diseases: liposomal rivastigmine formulations.

Journal: Drug development and industrial pharmacy 20110701

Title: Heterogeneous accumulation of fluorescent bile acids in primary rat hepatocytes does not correlate with their homogenous expression of ntcp.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20110701

Title: Bile acid malabsorption: an under-investigated differential diagnosis in patients presenting with diarrhea predominant irritable bowel syndrome type symptoms.

Journal: Scandinavian journal of gastroenterology 20110701

Title: Silver nanoparticles disrupt olfaction in Crucian carp (Carassius carassius) and Eurasian perch (Perca fluviatilis).

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20110701

Title: Effects of ORP150 on appearance and function of pancreatic beta cells following acute necrotizing pancreatitis.

Journal: Pathology, research and practice 20110615

Title: Genetic polymorphisms in Na+-taurocholate co-transporting polypeptide (NTCP) and ileal apical sodium-dependent bile acid transporter (ASBT) and ethnic comparisons of functional variants of NTCP among Asian populations.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20110601

Title: Upregulation of PIAS1 protects against sodium taurocholate-induced severe acute pancreatitis associated with acute lung injury.

Journal: Cytokine 20110601

Title: The G protein-coupled bile acid receptor, TGR5, stimulates gallbladder filling.

Journal: Molecular endocrinology (Baltimore, Md.) 20110601

Title: Studies in mice, hamsters, and rats demonstrate that repression of hepatic apoA-I expression by taurocholic acid in mice is not mediated by the farnesoid-X-receptor.

Journal: Journal of lipid research 20110601

Title: Bile acids decrease intracellular bilirubin levels in the cholestatic liver: implications for bile acid-mediated oxidative stress.

Journal: Journal of cellular and molecular medicine 20110501

Title: Lymphocyte function antigen-1 regulates neutrophil recruitment and tissue damage in acute pancreatitis.

Journal: British journal of pharmacology 20110501

Title: Organic anion transporter 3 mediates the efflux transport of an amphipathic organic anion, dehydroepiandrosterone sulfate, across the blood-brain barrier in mice.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20110501

Title: Relative acidity scale of glycine- and taurine-conjugated bile acids through ESI-MS measurements.

Journal: Steroids 20110501

Title: Early organ-specific mitochondrial dysfunction of jejunum and lung found in rats with experimental acute pancreatitis.

Journal: HPB : the official journal of the International Hepato Pancreato Biliary Association 20110501

Title: Pioglitazone: a promising therapeutic tool in sodium taurocholate-induced severe acute pancreatitis.

Journal: Digestive diseases and sciences 20110401

Title: Differential disposition of chenodeoxycholic acid versus taurocholic acid in response to acute troglitazone exposure in rat hepatocytes.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20110401

Title: Crystal structures of CmeR-bile acid complexes from Campylobacter jejuni.

Journal: Protein science : a publication of the Protein Society 20110401

Title: Antifungal evaluation of cholic acid and its derivatives on Candida albicans by microcalorimetry and chemometrics.

Journal: Analytica chimica acta 20110318

Title: Partial characterization of pyloric-duodenal lipase of gilthead seabream (Sparus aurata).

Journal: Fish physiology and biochemistry 20110301

Title: Human bone marrow-derived clonal mesenchymal stem cells inhibit inflammation and reduce acute pancreatitis in rats.

Journal: Gastroenterology 20110301

Title: Further characterization of the electrogenicity and pH sensitivity of the human organic anion-transporting polypeptides OATP1B1 and OATP1B3.

Journal: Molecular pharmacology 20110301

Title: Stability of liposomes containing bio-enhancers and tetraether lipids in simulated gastro-intestinal fluids.

Journal: International journal of pharmaceutics 20110227

Title: Rho-kinase signalling regulates trypsinogen activation and tissue damage in severe acute pancreatitis.

Journal: British journal of pharmacology 20110201

Title: The protective effects of Lipoxin A4 during the early phase of severe acute pancreatitis in rats.

Journal: Scandinavian journal of gastroenterology 20110201

Title: Human bile salt-dependent lipase efficiency on medium-chain acyl-containing substrates: control by sodium taurocholate.

Journal: Journal of biochemistry 20110201

Title: Nitric oxide-mediated inhibition of taurocholate uptake involves S-nitrosylation of NTCP.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20110201

Title: Functional characteristics of Lactobacillus fermentum F1.

Journal: Current microbiology 20110101

Title: Establishment of a secondary infection model of severe acute pancreatitis in swine.

Journal: Pancreas 20110101

Title: Differential effect of genetic variants of Na(+)-taurocholate co-transporting polypeptide (NTCP) and organic anion-transporting polypeptide 1B1 (OATP1B1) on the uptake of HMG-CoA reductase inhibitors.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20110101

Title: Effect of adjuvant-induced systemic inflammation in rats on hepatic disposition kinetics of taurocholate.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20110101

Title: Comparison of the expression and function of ATP binding cassette transporters in Caco-2 and T84 cells on stimulation by selected endogenous compounds and xenobiotics.

Journal: Drug metabolism and pharmacokinetics 20110101

Title: [Evaluation on hepatotoxicity caused by Dioscorea bulbifera based on analysis of bile acids].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20110101

Title: Prophylactic glycine administration attenuates pancreatic damage and inflammation in experimental acute pancreatitis.

Journal: Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20110101

Title: [Measurement of 75Se-SeHCAT abdominal retention in the initial diagnosis of Bile Acid Absorption (BAM)].

Journal: Revista espanola de medicina nuclear 20110101

Title: Profiling circulating and urinary bile acids in patients with biliary obstruction before and after biliary stenting.

Journal: PloS one 20110101

Title: Dietary cholesterol reduces plasma triacylglycerol in apolipoprotein E-null mice: suppression of lipin-1 and -2 in the glycerol-3-phosphate pathway.

Journal: PloS one 20110101

Title: [The dissolution test in biorelevant media as a prognostic tool for modeling of drug behavior in vivo].

Journal: Biomeditsinskaia khimiia 20110101

Title: Aeromicrobium halocynthiae sp. nov., a taurocholic acid-producing bacterium isolated from the marine ascidian Halocynthia roretzi.

Journal: International journal of systematic and evolutionary microbiology 20101201

Title: Mechanisms of the beneficial effect of hypertonic saline solution in acute pancreatitis.

Journal: Shock (Augusta, Ga.) 20101101

Title: Ameliorative effect of adalimumab on experimentally induced acute pancreatitis in rats.

Journal: Pancreas 20101101

Title: Anti-inflammatory effects of peritoneal lavage in acute pancreatitis.

Journal: Pancreas 20101101

Title: Extracts from the Mongolian traditional medicinal plants Dianthus versicolorFisch. and Lilium pumilum Delile stimulate bile flow in an isolated perfused rat liver model.

Journal: Journal of ethnopharmacology 20101005

Title: Taurocholic acid prevents biliary damage induced by hepatic artery ligation in cholestatic rats.

Journal: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20101001

Title: A novel recombinant snake venom metalloproteinase from Agkistrodon acutus protects against taurocholate-induced severe acute pancreatitis in rats.

Journal: Biochimie 20101001

Title: Hepatobiliary disposition of 3alpha,6alpha,7alpha,12alpha-tetrahydroxy-cholanoyl taurine: a substrate for multiple canalicular transporters.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20101001

Title: Fluo-cAMP is transported by multidrug resistance-associated protein isoform 4 in rat choroid plexus.

Journal: Journal of neurochemistry 20101001

Title: Inhibiting the initiation of Clostridium difficile spore germination using analogs of chenodeoxycholic acid, a bile acid.

Journal: Journal of bacteriology 20101001

Title: Phosphoinositide 3-kinase/protein kinase B signaling pathway is involved in estradiol 17β-D-glucuronide-induced cholestasis: complementarity with classical protein kinase C.

Journal: Hepatology (Baltimore, Md.) 20101001

Title: Defining primary bile acid diarrhea: making the diagnosis and recognizing the disorder.

Journal: Expert review of gastroenterology & hepatology 20101001

Title: Identification of inhibitor concentrations to efficiently screen and measure inhibition Ki values against solute carrier transporters.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20100911

Title: Potential implications for monitoring serum bile acid profiles in circulation with serum proteome for carbon tetrachloride-induced liver injury/regeneration model in mice.

Journal: Journal of proteome research 20100903

Title: Poly(ADP-ribose) polymerase inhibition modulates experimental acute necrotizing pancreatitis-induced oxidative stress, bacterial translocation and neopterin concentrations in rats.

Journal: Experimental biology and medicine (Maywood, N.J.) 20100901

Title: Effect of food components and dosing times on the oral pharmacokinetics of nifedipine in rats.

Journal: International journal of pharmaceutics 20100830

Title: Synthesis and in vitro evaluation of potential sustained release prodrugs via targeting ASBT.

Journal: International journal of pharmaceutics 20100830

Title: Bile acids regulate hepatic gluconeogenic genes and farnesoid X receptor via G(alpha)i-protein-coupled receptors and the AKT pathway.

Journal: Journal of lipid research 20100801

Title: Sulindac and its metabolites inhibit multiple transport proteins in rat and human hepatocytes.

Journal: The Journal of pharmacology and experimental therapeutics 20100801

Title: [Effects of gadolinium chloride on sodium taurocholate-induced pancreatitis in rats].

Journal: Revista do Colegio Brasileiro de Cirurgioes 20100801

Title: Inhibition of renin-angiotensin system in experimental acute pancreatitis in rats: a new therapeutic target?

Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20100701

Title: Hepatic uptake of the magnetic resonance imaging contrast agent Gd-EOB-DTPA: role of human organic anion transporters.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20100701

Title: ABCG5/ABCG8-independent biliary cholesterol excretion in lactating rats.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20100701

Title: Conditional Gata4 deletion in mice induces bile acid absorption in the proximal small intestine.

Journal: Gut 20100701

Title: Emodin enhances alveolar epithelial barrier function in rats with experimental acute pancreatitis.

Journal: World journal of gastroenterology 20100628

Title: Activated protein C improves the severity of severe acute pancreatitis via up-regulating the expressions of endothelial cell protein C receptor and thrombomodulin.

Journal: Digestive diseases and sciences 20100601

Title: The probiotic properties of Lactobacillus buchneri P2.

Journal: Journal of applied microbiology 20100601

Title: Sodium taurocholate inhibits intestinal adenoma formation in APCMin/+ mice, potentially through activation of the farnesoid X receptor.

Journal: Carcinogenesis 20100601

Title: Release of inflammatory mediators by adipose tissue during acute pancreatitis.

Journal: The Journal of pathology 20100601

Title: Evaluation of the endothelin receptor antagonists ambrisentan, darusentan, bosentan, and sitaxsentan as substrates and inhibitors of hepatobiliary transporters in sandwich-cultured human hepatocytes.

Journal: Canadian journal of physiology and pharmacology 20100601

Title: Inhibition of Na+-taurocholate Co-transporting polypeptide-mediated bile acid transport by cholestatic sulfated progesterone metabolites.

Journal: The Journal of biological chemistry 20100528

Title: Ordered transcriptional factor recruitment and epigenetic regulation of tnf-alpha in necrotizing acute pancreatitis.

Journal: Cellular and molecular life sciences : CMLS 20100501

Title: Contribution of high basolateral bile salt efflux to the lack of hepatotoxicity in rat in response to drugs inducing cholestasis in human.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20100501

Title: [Measurement of the transport activities of bile salt export pump using chemiluminescence detection method].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20100501

Title: Preparation and evaluation of spray-dried hyaluronic acid microspheres for intranasal delivery of fexofenadine hydrochloride.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20100416

Title: Formation of nano/micro-dispersions with improved dissolution properties upon dispersion of ritonavir melt extrudate in aqueous media.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20100416

Title: Influence of seeding density and extracellular matrix on bile Acid transport and mrp4 expression in sandwich-cultured mouse hepatocytes.

Journal: Molecular pharmaceutics 20100405

Title: Melatonin modulates the severity of taurocholate-induced acute pancreatitis in the rat.

Journal: Digestive diseases and sciences 20100401

Title: Cloning/characterization of the canine organic anion transporting polypeptide 1b4 (Oatp1b4) and classification of the canine OATP/SLCO members.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20100401

Title: A crucial role of nitric oxide in acute lung injury secondary to the acute necrotizing pancreatitis.

Journal: Human & experimental toxicology 20100401

Title: Mechanisms of membrane transport of poorly soluble drugs: role of micelles in oral absorption processes.

Journal: Journal of pharmaceutical sciences 20100301

Title: Leflunomide: is a new oral agent in treatment of acute pancreatitis?

Journal: Pancreas 20100301

Title: Role of high-mobility group box 1 protein in the pathogenesis of intestinal barrier injury in rats with severe acute pancreatitis.

Journal: Pancreas 20100301

Title: CO2 abdominal insufflation decreases local and systemic inflammatory response in experimental acute pancreatitis.

Journal: Pancreas 20100301

Title: Green tea catechin EGCG inhibits ileal apical sodium bile acid transporter ASBT.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20100301

Title: Protective effects of glycoursodeoxycholic acid in Barrett's esophagus cells.

Journal: Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus 20100201

Title: Use of cassette dosing in sandwich-cultured rat and human hepatocytes to identify drugs that inhibit bile acid transport.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20100201

Title: Protecting effects of a large dose of dexamethasone on spleen injury of rats with severe acute pancreatitis.

Journal: Journal of gastroenterology and hepatology 20100201

Title: Cathepsin L inactivates human trypsinogen, whereas cathepsin L-deletion reduces the severity of pancreatitis in mice.

Journal: Gastroenterology 20100201

Title: An in vitro assay to assess transporter-based cholestatic hepatotoxicity using sandwich-cultured rat hepatocytes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20100201

Title: Experimental acute biliary pancreatitis induced by retrograde infusion of bile acids into the mouse pancreatic duct.

Journal: Nature protocols 20100201

Title: Bile salt deconjugation and cholesterol removal from media by Lactobacillus strains used as probiotics in chickens.

Journal: Journal of the science of food and agriculture 20100115

Title: Hypertonic saline reduces metalloproteinase expression in liver during pancreatitis.

Journal: Clinical and experimental pharmacology & physiology 20100101

Title: Colocalization of MnSOD expression in response to oxidative stress.

Journal: Molecular carcinogenesis 20100101

Title: Functional characterization of mouse organic anion transporting peptide 1a4 in the uptake and efflux of drugs across the blood-brain barrier.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20100101

Title: Effects of carbon monoxide releasing molecule-liberated CO on severe acute pancreatitis in rats.

Journal: Cytokine 20100101

Title: Plasma bile acid concentrations in patients with human immunodeficiency virus infection receiving protease inhibitor therapy: possible implications for hepatotoxicity.

Journal: Pharmacotherapy 20100101

Title: Investigation of liposome formulation effects on rivastigmine transport through human colonic adenocarcinoma cell line (CACO-2).

Journal: Die Pharmazie 20100101

Title: Review: Bilirubin pKa studies: new models and theories indicate high pKa values in water, dimethylformamide and DMSO.

Journal: BMC biochemistry 20100101

Title: Orion: a glimpse of hope in life span extension?

Journal: Rejuvenation research 20100101

Title: Measurement of bile salt export pump transport activities using a fluorescent bile acid derivative.

Journal: Drug metabolism and pharmacokinetics 20100101

Title: Effect of procainhydrochloride on phospholipase A2 catalytic activity in sodium taurocholate-induced acute experimental pancreatitis in rats.

Journal: Digestive diseases (Basel, Switzerland) 20100101

Title: Delayed production of IL-18 in lungs and pancreas of rats with acute pancreatitis.

Journal: Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20100101

Title: A simple taurocholate-induced model of severe acute pancreatitis in rats.

Journal: World journal of gastroenterology 20091207

Title: The selective inhibition of type IV phosphodiesterase attenuates the severity of the acute pancreatitis in rats.

Journal: Digestive diseases and sciences 20091201

Title: Interaction of macrolide antibiotics with intestinally expressed human and rat organic anion-transporting polypeptides.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20091201

Title: PKC{epsilon}-dependent and -independent effects of taurolithocholate on PI3K/PKB pathway and taurocholate uptake in HuH-NTCP cell line.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20091201

Title: A photophysical study on the role of bile salt hydrophobicity in solubilizing amphotericin B aggregates.

Journal: Journal of pharmaceutical sciences 20091101

Title: A new mechanism for bile acid diarrhea: defective feedback inhibition of bile acid biosynthesis.

Journal: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20091101

Title: Effect of baicalin and octreotide on the expression levels of P-selectin protein in multiple organs of rats with severe acute pancreatitis.

Journal: Journal of gastroenterology and hepatology 20091101

Title: Effects of etanercept on sodium taurocholate-induced acute pancreatitis in rats.

Journal: Translational research : the journal of laboratory and clinical medicine 20091101

Title: Taurine-deficient diet up-regulated cystathionine beta-synthase monoallele in hemizygous cystathionine beta-synthase knockout mice.

Journal: Nutrition research (New York, N.Y.) 20091101

Title: New ideas about the solubility of drugs.

Journal: Chemistry & biodiversity 20091101

Title: Deletion of TRPC3 in mice reduces store-operated Ca2+ influx and the severity of acute pancreatitis.

Journal: Gastroenterology 20091001

Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Journal: Nature chemical biology 20091001

Title: In vitro bile acid binding and short-chain fatty acid profile of flax fiber and ethanol co-products.

Journal: Journal of medicinal food 20091001

Title: Bile acid transport in hypercholesterolemic resistant rabbits.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20090901

Title: In vitro inhibition of OATP-mediated uptake of phalloidin using bile acid derivatives.

Journal: Toxicology and applied pharmacology 20090815

Title: Thermodynamics and structure of inclusion compounds of tauro- and glyco-conjugated bile salts and beta-cyclodextrin.

Journal: Physical chemistry chemical physics : PCCP 20090707

Title: Down-regulation of hypoxia-inducible factor-1alpha by hyperbaric oxygen attenuates the severity of acute pancreatitis in rats.

Journal: Pancreas 20090701

Title: Acute pancreatitis: hypertonic saline increases heat shock proteins 70 and 90 and reduces neutrophil infiltration in lung injury.

Journal: Pancreas 20090701

Title: Identification, release and olfactory detection of bile salts in the intestinal fluid of the Senegalese sole (Solea senegalensis).

Journal: Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology 20090701

Title: Mutational analysis of uncharged polar residues and proline in the distal one-third (Thr130-Pro142) of the highly conserved region of mouse Slc10a2.

Journal: Bioscience, biotechnology, and biochemistry 20090701

Title: Polyproline-type helical-structured low-molecular weight heparin (LMWH)-taurocholate conjugate as a new angiogenesis inhibitor.

Journal: International journal of cancer 20090615

Title: Sodium taurocholate-dependent lipid efflux by ABCA1: effects of W590S mutation on lipid translocation and apolipoprotein A-I dissociation.

Journal: Journal of lipid research 20090601

Title: [Expression of survivin gene in a rat model of acute pancreatitis].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20090601

Title: Taurocholate potentiates ethanol-induced NF-kappaB activation and inhibits caspase-3 activity in cultured rat gastric mucosal cells.

Journal: Digestive diseases and sciences 20090501

Title: Participation of asparagine 370 and glutamine 235 in the catalysis by acid beta-glucosidase: the enzyme deficient in Gaucher disease.

Journal: Molecular genetics and metabolism 20090501

Title: Taurocholate feeding to bile duct ligated rats prevents caffeic acid-induced bile duct damage by changes in cholangiocyte VEGF expression.

Journal: Experimental biology and medicine (Maywood, N.J.) 20090401

Title: The proteome of mesenteric lymph during acute pancreatitis and implications for treatment.

Journal: JOP : Journal of the pancreas 20090309

Title: Solvent-mediated solid phase transformations of carbamazepine: Effects of simulated intestinal fluid and fasted state simulated intestinal fluid.

Journal: Journal of pharmaceutical sciences 20090301

Title: Caerulein or taurocholate induced enzymatic and histologic alterations in the isolated perfused rat pancreas.

Journal: Langenbeck's archives of surgery 20090301

Title: Endogenous catecholamine stimulates alveolar fluid clearance in rats with acute pancreatitis.

Journal: Respirology (Carlton, Vic.) 20090301

Title: Transbuccal delivery of 5-fluorouracil: permeation enhancement and pharmacokinetic study.

Journal: AAPS PharmSciTech 20090301

Title: [Effect of resveratrol-induced FasL up-regulation on the apoptosis of pancreatic acinar cells in rats with severe acute pancreatitis].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20090301

Title: Does the 3-aminobenzamide effect on bacterial translocation affect experimental acute necrotizing pancreatitis?

Journal: The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 20090301

Title: Novel oral absorption system containing polyamines and bile salts enhances drug transport via both transcellular and paracellular pathways across Caco-2 cell monolayers.

Journal: International journal of pharmaceutics 20090209

Title: Cell-permeable Tat-NBD peptide attenuates rat pancreatitis and acinus cell inflammation response.

Journal: World journal of gastroenterology 20090207

Title: Saline infusion through the pancreatic duct leads to changes in calcium homeostasis similar to those observed in acute pancreatitis.

Journal: Digestive diseases and sciences 20090201

Title: Solubilisation of dipalmitoylphosphatidylcholine bilayers by sodium taurocholate: a model to study the stability of liposomes in the gastrointestinal tract and their mechanism of interaction with a model bile salt.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20090201

Title: Surfactant-induced mobilisation of trace metals from estuarine sediment: implications for contaminant bioaccessibility and remediation.

Journal: Environmental pollution (Barking, Essex : 1987) 20090201

Title: Colloidal structures in media simulating intestinal fed state conditions with and without lipolysis products.

Journal: Pharmaceutical research 20090201

Title: Fibrogenesis in pediatric cholestatic liver disease: role of taurocholate and hepatocyte-derived monocyte chemotaxis protein-1 in hepatic stellate cell recruitment.

Journal: Hepatology (Baltimore, Md.) 20090201

Title: Matrix metalloproteinase-9 derived from polymorphonuclear neutrophils increases gut barrier dysfunction and bacterial translocation in rat severe acute pancreatitis.

Journal: Surgery 20090201

Title: Rosiglitazone attenuates the severity of sodium taurocholate-induced acute pancreatitis and pancreatitis-associated lung injury.

Journal: Archives of medical research 20090201

Title: Involvement of Mrp2/MRP2 in the species different excretion route of benzylpenicillin between rat and human.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20090201

Title: Transport evaluation of alendronate across Caco-2 cell monolayers.

Journal: Die Pharmazie 20090201

Title: Involvement of prostacyclin/IP receptors in decreased acid response of damaged stomachs--mediation by somatostatin/SST2 receptors.

Journal: Life sciences 20090130

Title: Administration of anti-Reg I and anti-PAPII antibodies worsens pancreatitis.

Journal: JOP : Journal of the pancreas 20090108

Title: Effect of platelet-activating factor antagonist WEB 2086 on microcirculatory disorders in acute experimental pancreatitis of graded severity.

Journal: Pancreas 20090101

Title: On enhancers and inhibitors of elastin-derived amyloidogenesis.

Journal: Nanomedicine (London, England) 20090101

Title: Rosiglitazone, a peroxisome proliferator-activated receptor gamma (PPARgamma)-specific agonist, as a modulator in experimental acute pancreatitis.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20090101

Title: Erythropoietin: a possible cytoprotective cytokine in acute necrotizing pancreatitis.

Journal: Journal of hepato-biliary-pancreatic surgery 20090101

Title: Identification, expression, and functional characterization of full-length and splice variants of murine organic anion transporting polypeptide 1b2.

Journal: Molecular pharmaceutics 20090101

Title: Development of mucoadhesive buccal films for the treatment of oral sub-mucous fibrosis: a preliminary study.

Journal: Pharmaceutical development and technology 20090101

Title: In vitro, but not in vivo, reversibility of peritoneal macrophages activation during experimental acute pancreatitis.

Journal: BMC immunology 20090101

Title: Physicochemical and biological characterization of monoketocholic acid, a novel permeability enhancer.

Journal: Molecular pharmaceutics 20090101

Title: Biliary sphincterotomy does not relate to diarrhoea or major changes in bile acid synthesis or plasma lipids.

Journal: Scandinavian journal of gastroenterology 20090101

Title: Physicochemical properties and antioxidant activity of gamma-oryzanol-loaded liposome formulations for topical use.

Journal: Pharmaceutical development and technology 20090101

Title: Recent advances in the understanding of bile acid malabsorption.

Journal: British medical bulletin 20090101

Title: Taurocholate-induced nitric oxide signaling and the ensuing production of reactive oxygen species lead to an increase in epithelial permeability in cultivated mouse gastric epithelium.

Journal: Digestive diseases and sciences 20081201

Title: Evaluation of the probiotic characteristics of newly isolated lactic acid bacteria.

Journal: Applied biochemistry and biotechnology 20081201

Title: Involvement of intestinal uptake transporters in the absorption of azithromycin and clarithromycin in the rat.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20081201

Title: Influence of La3+ ions on the egg-yolk phosphatidylcholine and sodium taurocholate self-assemblies in aqueous suspension.

Journal: Journal of colloid and interface science 20081201

Title: Optimization and validation of two miniaturized glucocerebrosidase enzyme assays for high throughput screening.

Journal: Combinatorial chemistry & high throughput screening 20081201

Title: Physical and chemical factors influencing the germination of Clostridium difficile spores.

Journal: Journal of applied microbiology 20081201

Title: Study on protecting effects of baicalin and octreotide on hepatic injury in rats with severe acute pancreatitis.

Journal: World journal of gastroenterology 20081114

Title: The bile acid turnover rate assessed with the (75)SeHCAT test is stable in chronic diarrhoea but slightly decreased in healthy subjects after a long period of time.

Journal: Digestive diseases and sciences 20081101

Title: Cardiovascular homeostasis in hypotension associated with initial stages of severe acute pancreatitis.

Journal: Pancreas 20081101

Title: Cloning of the dog bile salt export pump (BSEP; ABCB11) and functional comparison with the human and rat proteins.

Journal: Biopharmaceutics & drug disposition 20081101

Title: Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.

Journal: Journal of medicinal chemistry 20081009

Title: Texas Red transport across rat and dogfish shark (Squalus acanthias) choroid plexus.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20081001

Title: Effect of albumin on the biliary clearance of compounds in sandwich-cultured rat hepatocytes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20081001

Title: Surfactant dependent morphology of polymeric capsules of perfluorooctyl bromide: influence of polymer adsorption at the dichloromethane-water interface.

Journal: Journal of colloid and interface science 20081001

Title: Cholangiocyte bile salt transporters in cholesterol gallstone-susceptible and resistant inbred mouse strains.

Journal: Journal of gastroenterology and hepatology 20081001

Title: Study of the protective effects of dexamethasone on ileum mucosa injury in rats with severe acute pancreatitis.

Journal: Pancreas 20081001

Title: The effect of synacthen on acute necrotizing pancreatitis in rats.

Journal: Pancreas 20081001

Title: Study of thermodynamic parameters for solubilization of plant sterol and stanol in bile salt micelles.

Journal: Chemistry and physics of lipids 20080801

Title: Improvement of monocyte secretion function in a porcine pancreatitis model by continuous dose dependent veno-venous hemofiltration.

Journal: The International journal of artificial organs 20080801

Title: Statin pretreatment in experimental acute pancreatitis.

Journal: JOP : Journal of the pancreas 20080710

Title: Different bacterial strategies to degrade taurocholate.

Journal: Archives of microbiology 20080701

Title: Niemann-pick C1-like 1 mediates alpha-tocopherol transport.

Journal: Molecular pharmacology 20080701

Title: Cytosol-nucleus traffic and colocalization with FXR of conjugated bile acids in rat hepatocytes.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20080701

Title: Alpha-tocopheryl acetate is absorbed and hydrolyzed by Caco-2 cells comparative studies with alpha-tocopherol.

Journal: Chemistry and physics of lipids 20080701

Title: Pentoxifylline attenuates pulmonary inflammation and neutrophil activation in experimental acute pancreatitis.

Journal: Pancreas 20080701

Title: Proteasome inhibitor ameliorates severe acute pancreatitis and associated lung injury of rats.

Journal: World journal of gastroenterology 20080528

Title: Small-interference RNA gene knockdown of pancreatitis-associated proteins in rat acute pancreatitis.

Journal: Pancreas 20080501

Title: Permeation studies and histological examination of sheep nasal mucosa following administration of different nasal formulations with or without absorption enhancers.

Journal: Drug delivery 20080501

Title: In vitro methods can forecast the effects of intragastric residence on dosage form performance.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20080423

Title: Glutamate cysteine ligase up-regulation fails in necrotizing pancreatitis.

Journal: Free radical biology & medicine 20080415

Title: Metabolism and disposition of resveratrol in the isolated perfused rat liver: role of Mrp2 in the biliary excretion of glucuronides.

Journal: Journal of pharmaceutical sciences 20080401

Title: Bile salts and glycine as cogerminants for Clostridium difficile spores.

Journal: Journal of bacteriology 20080401

Title: Protein kinase Cdelta mediates cyclic adenosine monophosphate-stimulated translocation of sodium taurocholate cotransporting polypeptide and multidrug resistant associated protein 2 in rat hepatocytes.

Journal: Hepatology (Baltimore, Md.) 20080401

Title: [Effects of contrast medium on the pancreatic pathology in severe acute pancreatitis experiment with rats].

Journal: Zhonghua yi xue za zhi 20080325

Title: Sensitivity of Haloquadratum and Salinibacter to antibiotics and other inhibitors: implications for the assessment of the contribution of Archaea and Bacteria to heterotrophic activities in hypersaline environments.

Journal: FEMS microbiology ecology 20080301

Title: Acute pancreatitis severity is exacerbated by intestinal ischemia-reperfusion conditioned mesenteric lymph.

Journal: Surgery 20080301

Title: Taurocholate-induced pancreatitis: a model of severe necrotizing pancreatitis in mice.

Journal: Pancreas 20080301

Title: Pharmacokinetic and pharmacodynamic properties of biapenem, a carbapenem antibiotic, in rat experimental model of severe acute pancreatitis.

Journal: Pancreas 20080301

Title: The influence of sodium hyaluronate, L-leucine and sodium taurocholate on the nebulization of aqueous betamethasone-17-valerate suspensions.

Journal: AAPS PharmSciTech 20080301

Title: Hepatocyte growth factor increases uptake of estradiol 17beta-D-glucuronide and Oatp1 protein level in rat hepatocytes.

Journal: European journal of pharmacology 20080202

Title: Effects of resveratrol on calcium regulation in rats with severe acute pancreatitis.

Journal: European journal of pharmacology 20080202

Title: The role of NF-kappaB activation in the pathogenesis of acute pancreatitis.

Journal: Gut 20080201

Title: Non-synonymous polymorphisms in the human SLCO1B1 gene: an in vitro analysis of SNP c.1929A>C.

Journal: Molecular genetics and genomics : MGG 20080201

Title: Modulation of ileal bile acid transporter (ASBT) activity by depletion of plasma membrane cholesterol: association with lipid rafts.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20080201

Title: Establishment of an infected necrotizing pancreatitis model by retrograde pancreatic duct injection of sodium taurocholate and E. coli in rats.

Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20080201

Title: Phenotypic differences in PFIC2 and BRIC2 correlate with protein stability of mutant Bsep and impaired taurocholate secretion in MDCK II cells.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20080101

Title: Solubilization of sphingomyelin vesicles by addition of a bile salt.

Journal: Chemistry and physics of lipids 20080101

Title: Activation of MUC1 mucin expression by bile acids in human esophageal adenocarcinomatous cells and tissues is mediated by the phosphatidylinositol 3-kinase.

Journal: Surgery 20080101

Title: Obesity alters cytokine gene expression and promotes liver injury in rats with acute pancreatitis.

Journal: Obesity (Silver Spring, Md.) 20080101

Title: Dexamethasone affects inflammation but not trypsinogen activation in experimental acute pancreatitis.

Journal: European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 20080101

Title: Methylene blue improves hemodynamic shock but increases lipoperoxidation in severe acute pancreatitis pig model.

Journal: Acta cirurgica brasileira 20080101

Title: Deoxycholic acid induces the overexpression of intestinal mucin, MUC2, via NF-kB signaling pathway in human esophageal adenocarcinoma cells.

Journal: BMC cancer 20080101

Title: Combination of allopurinol and hyperbaric oxygen therapy: a new treatment in experimental acute necrotizing pancreatitis?

Journal: World journal of gastroenterology 20071214

Title: Development of simulated intestinal fluids containing nutrients as transport media in the Caco-2 cell culture model: assessment of cell viability, monolayer integrity and transport of a poorly aqueous soluble drug and a substrate of efflux mechanisms.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20071201

Title: A mouse model of acute biliary pancreatitis induced by retrograde pancreatic duct infusion of Na-taurocholate.

Journal: Gut 20071101

Title: Thymosin alpha 1 improves severe acute pancreatitis in rats via regulation of peripheral T cell number and cytokine serum level.

Journal: Journal of gastroenterology and hepatology 20071101

Title: Preferential increase of extracellular matrix expression relative to transforming growth factor beta1 in the pancreas during the early stage of acute hemorrhagic pancreatitis in rats.

Journal: Pancreas 20071101

Title: Acinar cell membrane disruption is an early event in experimental acute pancreatitis in rats.

Journal: Pancreas 20071101

Title: Evaluation of the effects of noniodinized and iodinized ionic contrast media and gadoteric acid in acute necrotizing pancreatitis: experimental study in rabbits.

Journal: Pancreas 20071101

Title: Adaptation of Cryptosporidium oocysts to different excystation conditions.

Journal: Parasitology 20071001

Title: Extrahepatic cholestasis downregulates Oatp1 by TNF-alpha signalling without affecting Oatp2 and Oatp4 expression and sodium-independent bile salt uptake in rat liver.

Journal: Liver international : official journal of the International Association for the Study of the Liver 20071001

Title: The therapeutic effect of oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine in rodents with acute necrotizing pancreatitis and its mechanism.

Journal: Pancreas 20071001

Title: Prophylactic effect of lafutidine against the adverse reaction induced in rat stomach by repeated administration of 5-fluorouracil.

Journal: Inflammopharmacology 20071001

Title: Preparation method of an ideal model of multiple organ injury of rat with severe acute pancreatitis.

Journal: World journal of gastroenterology 20070914

Title: Histopathological sequential changes in sodium taurocholate-induced acute pancreatitis.

Journal: JOP : Journal of the pancreas 20070907

Title: Involvement of prostaglandin E receptor EP3 subtype and prostacyclin IP receptor in decreased acid response in damaged stomach.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20070901

Title: Absorptive profile of chlorogenic acid in rats.

Journal: Die Pharmazie 20070901

Title: Involvement of carrier-mediated transport system in uptake of tetrodotoxin into liver tissue slices of puffer fish Takifugu rubripes.

Journal: Toxicon : official journal of the International Society on Toxinology 20070801

Title: Substrate-dependent drug-drug interactions between gemfibrozil, fluvastatin and other organic anion-transporting peptide (OATP) substrates on OATP1B1, OATP2B1, and OATP1B3.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20070801

Title: Glucuronidation converting methyl 1-(3,4-dimethoxyphenyl)-3-(3-ethylvaleryl)-4-hydroxy-6,7,8-trimethoxy-2-naphthoate (S-8921) to a potent apical sodium-dependent bile acid transporter inhibitor, resulting in a hypocholesterolemic action.

Journal: The Journal of pharmacology and experimental therapeutics 20070801

Title: Effects of Ala substitution for conserved Cys residues in mouse ileal and hepatic Na+-dependent bile acid transporters.

Journal: Bioscience, biotechnology, and biochemistry 20070801

Title: Absorption study of deoxycholic acid-heparin conjugate as a new form of oral anti-coagulant.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20070716

Title: Adaptive response to increased bile acids: induction of MDR1 gene expression and P-glycoprotein activity in renal epithelial cells.

Journal: Pflugers Archiv : European journal of physiology 20070701

Title: Human organic anion transporter 1B1 and 1B3 function as bidirectional carriers and do not mediate GSH-bile acid cotransport.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20070701

Title: Intestinal bile salt absorption in Atp8b1 deficient mice.

Journal: Journal of hepatology 20070701

Title: Taurocholic acid feeding prevents tumor necrosis factor-alpha-induced damage of cholangiocytes by a PI3K-mediated pathway.

Journal: Experimental biology and medicine (Maywood, N.J.) 20070701

Title: Cytotoxicity of submicron emulsions and solid lipid nanoparticles for dermal application.

Journal: International journal of pharmaceutics 20070607

Title: Protein-protein interactions and membrane localization of the human organic solute transporter.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20070601

Title: Differential inhibition of rat and human Na+-dependent taurocholate cotransporting polypeptide (NTCP/SLC10A1)by bosentan: a mechanism for species differences in hepatotoxicity.

Journal: The Journal of pharmacology and experimental therapeutics 20070601

Title: 4-phenylbutyrate enhances the cell surface expression and the transport capacity of wild-type and mutated bile salt export pumps.

Journal: Hepatology (Baltimore, Md.) 20070601

Title: Effect of early and late antibiotic treatment in experimental acute pancreatitis in rats.

Journal: Langenbeck's archives of surgery 20070501

Title: Cytoprotective effects of taurocholic acid feeding on the biliary tree after adrenergic denervation of the liver.

Journal: Liver international : official journal of the International Association for the Study of the Liver 20070501

Title: Pioglitazone attenuates the severity of sodium taurocholate-induced severe acute pancreatitis.

Journal: World journal of gastroenterology 20070407

Title: Involvement of bile salt export pump in flutamide-induced cholestatic hepatitis.

Journal: Biological & pharmaceutical bulletin 20070401

Title: [Role of cholesterol phospholipid cholic acid and mucoprotein in the crystallization of gallbladder stone].

Journal: Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20070401

Title: Novel cationic and neutral glycocholic acid and polyamine conjugates able to inhibit transporters involved in hepatic and intestinal bile acid uptake.

Journal: Bioorganic & medicinal chemistry 20070315

Title: Linuron and carbaryl differentially impair baseline amino acid and bile salt olfactory responses in three salmonids.

Journal: Toxicology 20070307

Title: Dietary nitrate increases gastric mucosal blood flow and mucosal defense.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20070301

Title: Two N-linked glycans are required to maintain the transport activity of the bile salt export pump (ABCB11) in MDCK II cells.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20070301

Title: In vitro-in vivo correlation of hepatobiliary drug clearance in humans.

Journal: Clinical pharmacology and therapeutics 20070301

Title: Taurocholic acid does not induce apoptosis in HCT116 cells regardless of its intracellular concentration.

Journal: Bioscience, biotechnology, and biochemistry 20070301

Title: Effect of parenteral and early intrajejunal nutrition on pancreatic digestive enzyme synthesis, storage and discharge in dog models of acute pancreatitis.

Journal: World journal of gastroenterology 20070221

Title: Enhancing effect of surfactants on fexofenadine.HCl transport across the human nasal epithelial cell monolayer.

Journal: International journal of pharmaceutics 20070207

Title: Niemann-Pick C1-like 1 overexpression facilitates ezetimibe-sensitive cholesterol and beta-sitosterol uptake in CaCo-2 cells.

Journal: The Journal of pharmacology and experimental therapeutics 20070201

Title: Evidence of Oatp and Mdr1 in cryopreserved rat hepatocytes.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20070201

Title: Relationship between the apoptosis and notch-1 expression in acute pancreatitis.

Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20070201

Title: Bias in estimation of transporter kinetic parameters from overexpression systems: Interplay of transporter expression level and substrate affinity.

Journal: The Journal of pharmacology and experimental therapeutics 20070101

Title: Effects of bosentan, an endothelin receptor antagonist, on bile salt export pump and multidrug resistance-associated protein 2.

Journal: Biopharmaceutics & drug disposition 20070101

Title: Mutations and polymorphisms in the bile salt export pump and the multidrug resistance protein 3 associated with drug-induced liver injury.

Journal: Pharmacogenetics and genomics 20070101

Title: Acute pancreatitis affects non-parenchymal liver cells by a mechanism dependent on platelet-activating factor.

Journal: Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20070101

Title: Taurocholate and taurodeoxycholate: gel formation and protonation constants.

Journal: Annali di chimica 20070101

Title: Experimental model of severe acute pancreatitis in rabbits.

Journal: Acta cirurgica brasileira 20070101

Title: Use of sandwich-cultured hepatocytes to evaluate impaired bile acid transport as a mechanism of drug-induced hepatotoxicity.

Journal: Molecular pharmaceutics 20070101

Title: Cloning and expression of SLC10A4, a putative organic anion transport protein.

Journal: World journal of gastroenterology 20061114

Title: Dexamethasone mediates protection against acute pancreatitis via upregulation of pancreatitis-associated proteins.

Journal: World journal of gastroenterology 20061114

Title: Lipid composition effect on permeability across PAMPA.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20061101

Title: Time course of lung injury in rat acute pancreatitis.

Journal: Intensive care medicine 20061101

Title: Molecular determinants in the transport of a bile acid-derived diagnostic agent in tumoral and nontumoral cell lines of human liver.

Journal: The Journal of pharmacology and experimental therapeutics 20061101

Title: Role of hepatic opioid receptors in the regulation of bile excretion.

Journal: Bulletin of experimental biology and medicine 20061101

Title: OATP8/1B3-mediated cotransport of bile acids and glutathione: an export pathway for organic anions from hepatocytes?

Journal: The Journal of biological chemistry 20061013

Title: Importance of bile acids for novel oral absorption system containing polyamines to improve intestinal absorption.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20061010

Title: Use of novel cationic bile salts in cholesterol crystallization and solubilization in vitro.

Journal: Biochimica et biophysica acta 20061001

Title: Ritonavir, saquinavir, and efavirenz, but not nevirapine, inhibit bile acid transport in human and rat hepatocytes.

Journal: The Journal of pharmacology and experimental therapeutics 20060901

Title: The mechanism of ABCG5/ABCG8 in biliary cholesterol secretion in mice.

Journal: Journal of lipid research 20060901

Title: Inhibition of bile acid transport across Na+/taurocholate cotransporting polypeptide (SLC10A1) and bile salt export pump (ABCB 11)-coexpressing LLC-PK1 cells by cholestasis-inducing drugs.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20060901

Title: Use of cryopreserved human hepatocytes in sandwich culture to measure hepatobiliary transport.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20060901

Title: Biorelevant dissolution media as a predictive tool for glyburide a class II drug.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20060901

Title: Effects of sodium taurocholate on the absorption of inhaled 99mTc-DTPA.

Journal: Pharmaceutical research 20060901

Title: Deoxycholic acid formation in gnotobiotic mice associated with human intestinal bacteria.

Journal: Lipids 20060901

Title: Gastroprotective and ulcer-healing activity of oleanolic acid derivatives: in vitro-in vivo relationships.

Journal: Life sciences 20060829

Title: Effects of immunosuppressive and immunostimulative treatment on pancreatic injury and mortality in severe acute experimental pancreatitis.

Journal: Pancreas 20060801

Title: Inhibition of cyclooxygenase-2 in experimental severe acute pancreatitis.

Journal: Clinics (Sao Paulo, Brazil) 20060801

Title: Pancreatic regenerating protein (reg I) and reg I receptor mRNA are upregulated in rat pancreas after induction of acute pancreatitis.

Journal: World journal of gastroenterology 20060728

Title: Organic anion transporting polypeptide-C mediates arsenic uptake in HEK-293 cells.

Journal: Journal of biomedical science 20060701

Title: Interaction of native bile acids with human apical sodium-dependent bile acid transporter (hASBT): influence of steroidal hydroxylation pattern and C-24 conjugation.

Journal: Pharmaceutical research 20060701

Title: Pineal hormone melatonin: solubilization studies in model aqueous gastrointestinal environments.

Journal: Current drug delivery 20060701

Title: The stability of insulin in solid formulations containing melezitose and starch. Effects of processing and excipients.

Journal: Drug development and industrial pharmacy 20060701

Title: Identification of functionally relevant residues of the rat ileal apical sodium-dependent bile acid cotransporter.

Journal: The Journal of biological chemistry 20060616

Title: Salicylate enhances rat gastric gelatinase activity.

Journal: The Journal of surgical research 20060615

Title: Novel non-systemic inhibitor of ileal apical Na+-dependent bile acid transporter reduces serum cholesterol levels in hamsters and monkeys.

Journal: European journal of pharmacology 20060606

Title: Captopril, an Angiotensin-converting enzyme inhibitor, attenuates the severity of acute pancreatitis in rats by reducing expression of matrix metalloproteinase 9.

Journal: The Tohoku journal of experimental medicine 20060601

Title: Effects of choleretics on bile compositions drained from patients with pigment gallstone.

Journal: Chinese journal of integrative medicine 20060601

Title: Single-step analysis of individual conjugated bile acids in human bile using 1H NMR spectroscopy.

Journal: Lipids 20060601

Title: Drug and bile acid transporters in rosuvastatin hepatic uptake: function, expression, and pharmacogenetics.

Journal: Gastroenterology 20060501

Title: Gastroprotective and ulcer healing effect of ferruginol in mice and rats: assessment of its mechanism of action using in vitro models.

Journal: Life sciences 20060418

Title: Bile acids alter the subcellular localization of CNT2 (concentrative nucleoside cotransporter) and increase CNT2-related transport activity in liver parenchymal cells.

Journal: The Biochemical journal 20060415

Title: Mice lacking Mrp3 (Abcc3) have normal bile salt transport, but altered hepatic transport of endogenous glucuronides.

Journal: Journal of hepatology 20060401

Title: Normal or increased bile acid uptake in isolated mucosa from patients with bile acid malabsorption.

Journal: European journal of gastroenterology & hepatology 20060401

Title: Improvement of interfacial protein stability by CHAPS.

Journal: Biotechnology letters 20060401

Title: Lung-surfactant-meconium interaction: in vitro study in bulk and at the air-solution interface.

Journal: Langmuir : the ACS journal of surfaces and colloids 20060328

Title: Design of novel synthetic MTS conjugates of bile acids for site-directed sulfhydryl labeling of cysteine residues in bile acid binding and transporting proteins.

Journal: Bioorganic & medicinal chemistry letters 20060315

Title: Novel oral formulation safely improving intestinal absorption of poorly absorbable drugs: utilization of polyamines and bile acids.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20060310

Title: Effects of bile acids on biliary epithelial cell proliferation and portal fibroblast activation using rat liver slices.

Journal: Laboratory investigation; a journal of technical methods and pathology 20060301

Title: A multi-analytical platform approach to the metabonomic analysis of plasma from normal and Zucker (fa/fa) obese rats.

Journal: Molecular bioSystems 20060301

Title: Inhibitory effects of choleretic hydroxyacetophenones on ileal bile acid transport in rats.

Journal: Life sciences 20060227

Title: The human transcription factor AP-1 is a mediator of bile acid-induced liver cell apoptosis.

Journal: Biochemical and biophysical research communications 20060217

Title: Bicarbonate-rich choleresis induced by secretin in normal rat is taurocholate-dependent and involves AE2 anion exchanger.

Journal: Hepatology (Baltimore, Md.) 20060201

Title: The novel formulation design of self-emulsifying drug delivery systems (SEDDS) type O/W microemulsion III: the permeation mechanism of a poorly water soluble drug entrapped O/W microemulsion in rat isolated intestinal membrane by the Ussing chamber method.

Journal: Drug metabolism and pharmacokinetics 20060201

Title: Development of the isolated dual perfused rat liver model as an improved reperfusion model for transplantation research.

Journal: The International journal of artificial organs 20060201

Title: Kinetics and mechanisms of cholesterol esterase inhibition by cardiovascular drugs in vitro.

Journal: Indian journal of biochemistry & biophysics 20060201

Title: Overexpression and characterization of a lipase from Bacillus subtilis.

Journal: Protein expression and purification 20060101

Title: [Colocalized expression of Fas and Fas-ligand in acute pancreatitis and its correlation with cell apoptosis].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20060101

Title: Uptake of ursodeoxycholate and its conjugates by human hepatocytes: role of Na(+)-taurocholate cotransporting polypeptide (NTCP), organic anion transporting polypeptide (OATP) 1B1 (OATP-C), and oatp1B3 (OATP8).

Journal: Molecular pharmaceutics 20060101

Title: High-speed screening and QSAR analysis of human ATP-binding cassette transporter ABCB11 (bile salt export pump) to predict drug-induced intrahepatic cholestasis.

Journal: Molecular pharmaceutics 20060101

Title: Hepatobiliary disposition in primary cultures of dog and monkey hepatocytes.

Journal: Molecular pharmaceutics 20060101

Title: Efflux mechanism of taurocholate across the rat intestinal basolateral membrane.

Journal: Molecular pharmaceutics 20060101

Title: Adsorption of bile acid by chitosan salts prepared with cinnamic acid and analogue compounds.

Journal: Journal of biomaterials science. Polymer edition 20060101

Title: The role of adenosine A2a receptors in experimental acute pancreatitis.

Journal: Advances in medical sciences 20060101

Title: Transport by vesicles of glycine- and taurine-conjugated bile salts and taurolithocholate 3-sulfate: a comparison of human BSEP with rat Bsep.

Journal: Biochimica et biophysica acta 20051230

Title: Therapeutic effect of DA-9601 on chronic reflux gastritis induced by sodium taurocholate in rats.

Journal: World journal of gastroenterology 20051221

Title: Rectal and vaginal administration of insulin-chitosan formulations: an experimental study in rabbits.

Journal: Journal of drug targeting 20051201

Title: Deposition of insulin powders for inhalation in vitro and pharmacodynamic evaluation of absorption promoters in rats.

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20051201

Title: Effect of IL-4 on altered expression of complement activation regulators in rat pancreatic cells during severe acute pancreatitis.

Journal: World journal of gastroenterology 20051121

Title: Activation of CFTR by ASBT-mediated bile salt absorption.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20051101

Title: Synthesis of phospholipid-conjugated bile salts and interaction of bile salt-coated liposomes with cultured hepatocytes.

Journal: Journal of lipid research 20051101

Title: Uptake of bilirubin into HepG2 cells assayed by thermal lens spectroscopy. Function of bilitranslocase.

Journal: The FEBS journal 20051101

Title: The cannabinoid 1 receptor antagonist, AM251, prolongs the survival of rats with severe acute pancreatitis.

Journal: The Tohoku journal of experimental medicine 20051001

Title: Dephosphorylation of Ser-226 facilitates plasma membrane retention of Ntcp.

Journal: The Journal of biological chemistry 20050930

Title: Bile acid transport in sister of P-glycoprotein (ABCB11) knockout mice.

Journal: Biochemistry 20050920

Title: Discovery of potent, nonsystemic apical sodium-codependent bile acid transporter inhibitors (Part 1).

Journal: Journal of medicinal chemistry 20050908

Title: Discovery of potent, nonsystemic apical sodium-codependent bile acid transporter inhibitors (Part 2).

Journal: Journal of medicinal chemistry 20050908

Title: Morphological and electrophysiological examination of olfactory sensory neurons during the early developmental prolarval stage of the sea lamprey Petromyzon marinus L.

Journal: Journal of neurocytology 20050901

Title: Bile salt export pump (BSEP/ABCB11) can transport a nonbile acid substrate, pravastatin.

Journal: The Journal of pharmacology and experimental therapeutics 20050801

Title: Development of stably transfected monolayer overexpressing the human apical sodium-dependent bile acid transporter (hASBT).

Journal: Pharmaceutical research 20050801

Title: Effect of the ulcerogenic agents ethanol, acetylsalicylic acid and taurocholate on actin cytoskeleton and cell motility in cultured rat gastric mucosal cells.

Journal: World journal of gastroenterology 20050714

Title: Biliary excretion of taurocholate, organic anions and vinblastine in rats with alpha-naphthylisothiocyanate-induced cholestasis.

Journal: Journal of gastroenterology and hepatology 20050701

Title: Study of energy transfer from 7-amino coumarin donors to the rhodamine 6G acceptor in lecithin vesicles and sodium taurocholate-lecithin mixed aggregates.

Journal: The journal of physical chemistry. B 20050623

Title: Gender differences in renal tubular taurocholate transport.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20050601

Title: Reply to the comment on 'Two-dimensional NMR study on the structures of micelles of sodium taurocholate'.

Journal: The journal of physical chemistry. B 20050519

Title: Cholesterol modulates human intestinal sodium-dependent bile acid transporter.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20050501

Title: Hepatic pharmacokinetics of taurocholate in the normal and cholestatic rat liver.

Journal: British journal of pharmacology 20050501

Title: mRNA for pancreatic uncoupling protein 2 increases in two models of acute experimental pancreatitis in rats and mice.

Journal: Cell and tissue research 20050501

Title: Secretin activation of the apical Na+-dependent bile acid transporter is associated with cholehepatic shunting in rats.

Journal: Hepatology (Baltimore, Md.) 20050501

Title: Mild hypothermia protects against sodium taurocholate (NaTc)-induced acute pancreatitis in rats with adverse effects on serum cytokines.

Journal: Pancreas 20050501

Title: Biliary excretion of olmesartan, an anigotensin II receptor antagonist, in the rat.

Journal: Journal of gastroenterology and hepatology 20050501

Title: Nasal drug delivery of sumatriptan succinate.

Journal: Die Pharmazie 20050501

Title: Citrus juices inhibit the function of human organic anion-transporting polypeptide OATP-B.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20050401

Title: Therapeutic effects and possible mechanisms of a snake venom preparation in the fibrotic rat liver.

Journal: Digestive diseases and sciences 20050401

Title: Bile-induced laryngitis: is there a basis in evidence?

Journal: The Annals of otology, rhinology, and laryngology 20050301

Title: Effects of dietary taurocholate, fat and protein on the storage and metabolism of dietary beta-carotene and alpha-tocopherol in ferrets.

Journal: International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20050301

Title: The heteromeric organic solute transporter alpha-beta, Ostalpha-Ostbeta, is an ileal basolateral bile acid transporter.

Journal: The Journal of biological chemistry 20050225

Title: Xenobiotics inhibit hepatic uptake and biliary excretion of taurocholate in rat hepatocytes.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20050201

Title: Extrinsic denervation alters postprandial absorption of glucose and glutamine in the ileum: implications for small bowel transplantation.

Journal: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20050201

Title: Quantitative estimation of the effects of bile salt surfactant systems on insulin stability and permeability in the rat intestine using a mass balance model.

Journal: The Journal of pharmacy and pharmacology 20050201

Title: Effect of resveratrol on activation of nuclear factor kappa-B and inflammatory factors in rat model of acute pancreatitis.

Journal: World journal of gastroenterology 20050128

Title: Pituitary adenylate cyclase activating-peptide and its receptor antagonists in development of acute pancreatitis in rats.

Journal: World journal of gastroenterology 20050128

Title: Regulation of taurocholate transport in freshly isolated proximal tubular cells of the rat kidney by protein kinases.

Journal: Nephron. Physiology 20050101

Title: Transport of prostaglandin E1 across the blood-brain barrier in rats.

Journal: The Journal of pharmacy and pharmacology 20050101

Title: Is there a role of taurine bromamine in inflammation? Interactive effects with nitrite and hydrogen peroxide.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20050101

Title: Pathologic alterations detected in acute pancreatitis induced by sodium taurocholate in rats and therapeutic effects of curcumin, ciprofloxacin and metronidazole combination.

Journal: Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20050101

Title: The effect of activated protein C on experimental acute necrotizing pancreatitis.

Journal: Critical care (London, England) 20050101

Title: Involvement of multiple transporters in the efflux of 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors across the blood-brain barrier.

Journal: The Journal of pharmacology and experimental therapeutics 20041201

Title: Oxygen in the alveolar air space mediates lung inflammation in acute pancreatitis.

Journal: Free radical biology & medicine 20041115

Title: The effect of various liposome formulations on insulin penetration across Caco-2 cell monolayer.

Journal: Life sciences 20041022

Title: Tumor necrosis factor alpha antibody prevents brain damage of rats with acute necrotizing pancreatitis.

Journal: World journal of gastroenterology 20041001

Title: Induction of cholestasis in the perfused rat liver by 2-aminoethyl diphenylborate, an inhibitor of the hepatocyte plasma membrane Ca2+ channels.

Journal: Journal of gastroenterology and hepatology 20041001

Title: Biliary excretion of bile acids and organic anions in rats with dichloroethylene-induced bile canalicular injury.

Journal: Journal of gastroenterology 20041001

Title: Hepatic clearance and drug metabolism using isolated perfused rat liver.

Journal: Current protocols in pharmacology 20041001

Title: Effects of colchicine on the maximum biliary excretion of cholephilic compounds in rats.

Journal: Journal of gastroenterology and hepatology 20040901

Title: Regulation of bile acid synthesis under reconstructed enterohepatic circulation in rats.

Journal: Steroids 20040901

Title: Comparison of Cryptosporidium parvum development in various cell lines for screening in vitro drug testing.

Journal: The Southeast Asian journal of tropical medicine and public health 20040901

Title: Commercially available chemicals that mimic a deposit feeder's (Arenicola marina) digestive solubilization of lipids.

Journal: Environmental science & technology 20040815

Title: Involvement of mast cells in basal and neurotensin-induced intestinal absorption of taurocholate in rats.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20040801

Title: Connexin 26-mediated gap junctional intercellular communication suppresses paracellular permeability of human intestinal epithelial cell monolayers.

Journal: Experimental cell research 20040801

Title: Importance of cytokines, nitric oxide, and apoptosis in the pathological process of necrotizing pancreatitis in rats.

Journal: Pancreas 20040801

Title: Comparison of the arrhythmogenic effects of tauro- and glycoconjugates of cholic acid in an in vitro study of rat cardiomyocytes.

Journal: BJOG : an international journal of obstetrics and gynaecology 20040801

Title: Chemotactic response of Helicobacter pylori to human plasma and bile.

Journal: Journal of medical microbiology 20040801

Title: Insertion and partition of sodium taurocholate into egg phosphatidylcholine vesicles.

Journal: Pharmaceutical research 20040801

Title: Influence of PMN leukocyte-mediated pancreatic damage on the systemic immune response in severe acute pancreatitis in rats.

Journal: Digestive diseases and sciences 20040801

Title: Effects of octreotide on acute necrotizing pancreatitis in rabbits.

Journal: World journal of gastroenterology 20040715

Title: Taurocholate transport by hepatic and intestinal bile acid transporters is independent of FIC1 overexpression in Madin-Darby canine kidney cells.

Journal: Journal of gastroenterology and hepatology 20040701

Title: The role of the glucocorticoid-dependent mechanism in the progression of sodium taurocholate-induced acute pancreatitis in the rat.

Journal: Pancreas 20040701

Title: Identification of phalloidin uptake systems of rat and human liver.

Journal: Biochimica et biophysica acta 20040701

Title: Effects of secretagogues and bile acids on mitochondrial membrane potential of pancreatic acinar cells: comparison of different modes of evaluating DeltaPsim.

Journal: The Journal of biological chemistry 20040625

Title: Carboxyl ester lipase cofractionates with scavenger receptor BI in hepatocyte lipid rafts and enhances selective uptake and hydrolysis of cholesteryl esters from HDL3.

Journal: The Journal of biological chemistry 20040625

Title: Endothelin receptor antagonists are not beneficial in the therapy of acute experimental pancreatitis.

Journal: Langenbeck's archives of surgery 20040601

Title: Differential expression of cholangiocyte and ileal bile acid transporters following bile acid supplementation and depletion.

Journal: World journal of gastroenterology 20040515

Title: Cross-talk between protein kinases Czeta and B in cyclic AMP-mediated sodium taurocholate co-transporting polypeptide translocation in hepatocytes.

Journal: The Journal of biological chemistry 20040514

Title: Lack of biliary lipid excretion in the little skate, Raja erinacea, indicates the absence of functional Mdr2, Abcg5, and Abcg8 transporters.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20040501

Title: Organic anion transport in choroid plexus from wild-type and organic anion transporter 3 (Slc22a8)-null mice.

Journal: American journal of physiology. Renal physiology 20040501

Title: Absorption of the cholic acid-conjugated peptide hormone cholylsecretin from the rat ileum in vivo.

Journal: Acta physiologica Scandinavica 20040501

Title: Bile salts affect epithelial restitution.

Journal: Journal of the American College of Surgeons 20040501

Title: A mouse genetic model for familial cholestasis caused by ATP8B1 mutations reveals perturbed bile salt homeostasis but no impairment in bile secretion.

Journal: Human molecular genetics 20040415

Title: Effect of simulated intestinal fluid on drug permeability estimation across Caco-2 monolayers.

Journal: International journal of pharmaceutics 20040415

Title: Ontogenetic development of rat intestinal bile acid transport requires thyroxine but not corticosterone.

Journal: Pediatric research 20040401

Title: Biliary excretion of azelnidipine, a calcium antagonist, in rats.

Journal: Journal of gastroenterology and hepatology 20040401

Title: Absorption of taurocholic acid by the ileum of normal and transgenic DeltaF508 cystic fibrosis mice.

Journal: The Journal of pharmacy and pharmacology 20040401

Title: Dissolution media simulating the intralumenal composition of the small intestine: physiological issues and practical aspects.

Journal: The Journal of pharmacy and pharmacology 20040401

Title: Ca2+-dependent protein kinase C isoforms induce cholestasis in rat liver.

Journal: The Journal of biological chemistry 20040312

Title: Molecular cloning and functional characterization of the bovine (Bos taurus) organic anion transporting polypeptide Oatp1a2 (Slco1a2).

Journal: Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20040301

Title: Beneficial effect of iloprost on the course of acute taurocholate pancreatitis in rats and its limitation by antecedent acute ethanol intake.

Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20040301

Title: Ethnicity-dependent polymorphism in Na+-taurocholate cotransporting polypeptide (SLC10A1) reveals a domain critical for bile acid substrate recognition.

Journal: The Journal of biological chemistry 20040220

Title: Excluded volume effect of rat intestinal mucin on taurocholate/phosphatidylcholine mixed micelles.

Journal: Journal of colloid and interface science 20040215

Title: Surfactant-facilitated crystallization of dihydrate carbamazepine during dissolution of anhydrous polymorph.

Journal: Journal of pharmaceutical sciences 20040201

Title: Alteration of the enterohepatic recirculation of bile acids in rats after exposure to ionizing radiation.

Journal: Canadian journal of physiology and pharmacology 20040201

Title: A progressive familial intrahepatic cholestasis type 2 mutation causes an unstable, temperature-sensitive bile salt export pump.

Journal: Journal of hepatology 20040101

Title: The effect of combination therapy of hyperbaric oxygen, meropenem, and selective nitric oxide synthase inhibitor in experimental acute pancreatitis.

Journal: Pancreas 20040101

Title: Infliximab: a new therapeutic agent in acute pancreatitis?

Journal: Pancreas 20040101

Title: Mobilization of xanthine oxidase from the gastrointestinal tract in acute pancreatitis.

Journal: BMC gastroenterology 20040101

Title: Beneficial effects of N-acetylcysteine on sodium taurocholate-induced pancreatitis in rats.

Journal: Journal of gastroenterology 20040101

Title: Transepithelial electrical resistance is not a reliable measurement of the Caco-2 monolayer integrity in Transwell.

Journal: Drug delivery 20040101

Title: Colonoscopy and SeHCAT for investigation of chronic diarrhea.

Journal: Digestion 20040101

Title: Mechanism of acute pancreatitis exacerbation by enteral bile-pancreatic juice exclusion.

Journal: Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20040101

Title: [Concentration changes of amylase in vitreous humor of acute pancreatitis associated with different postmortem interval in rabbits].

Journal: Fa yi xue za zhi 20040101

Title: Inhibition of apolipoprotein B secretion by taurocholate is controlled by the N-terminal end of the protein in rat hepatoma McArdle-RH7777 cells.

Journal: Biochimica et biophysica acta 20031230

Title: Bile salts regulate intestinal epithelial cell migration by nuclear factor-kappa B-induced expression of transforming growth factor-beta.

Journal: Journal of the American College of Surgeons 20031201

Title: Unique inhibition of bile salt-induced apoptosis by lecithins and cytoprotective bile salts in immortalized mouse cholangiocytes.

Journal: Digestive diseases and sciences 20031201

Title: Substrate specificities of rat oatp1 and ntcp: implications for hepatic organic anion uptake.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20031101

Title: Evaluation of hepatotoxic potential of drugs by inhibition of bile-acid transport in cultured primary human hepatocytes and intact rats.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20031101

Title: Effect of mdr2 mutation with combined tandem disruption of canalicular glycoprotein transporters by cyclosporine A on bile formation in mice.

Journal: Pharmacological research 20031101

Title: Cyclooxygenase isozymes involved in adaptive functional responses in rat stomach after barrier disruption.

Journal: The Journal of pharmacology and experimental therapeutics 20031101

Title: Characterization of the transport of the bicyclic peptide phalloidin by human hepatic transport proteins.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20031101

Title: Role of bile in intestinal barrier function and its inhibitory effect on bacterial translocation in obstructive jaundice in rats.

Journal: The Journal of surgical research 20031101

Title: Hepatic canalicular membrane transport of bile salt in C57L/J and AKR/J mice: implications for cholesterol gallstone formation.

Journal: The Journal of membrane biology 20031101

Title: In vitro system to evaluate oral absorption of poorly water-soluble drugs: simultaneous analysis on dissolution and permeation of drugs.

Journal: Pharmaceutical research 20031001

Title: The endothelin-1 receptor antagonists ameliorate histology and ultrastructural alterations in the pancreas and decrease trypsinogen activation in severe taurocholate pancreatitis in rats.

Journal: International journal of experimental pathology 20031001

Title: Effect of maternal obstructive cholestasis during pregnancy on the biliary transport of horseradish peroxidase in the rat offspring.

Journal: Clinical science (London, England : 1979) 20030901

Title: Intestinal absorption of the bile acid analogue 75Se-homocholic acid-taurine is increased in primary biliary cirrhosis, and reverts to normal during ursodeoxycholic acid administration.

Journal: Gut 20030901

Title: The effect of endothelin-1 receptor antagonists in acute experimental pancreatitis in the rats.

Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20030901

Title: Characterization of the role of polar amino acid residues within predicted transmembrane helix 17 in determining the substrate specificity of multidrug resistance protein 3.

Journal: Biochemistry 20030826

Title: Mechanisms by which cAMP increases bile acid secretion in rat liver and canalicular membrane vesicles.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20030801

Title: N-glycosylation controls functional activity of Oatp1, an organic anion transporter.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20030801

Title: Cotransport of reduced glutathione with bile salts by MRP4 (ABCC4) localized to the basolateral hepatocyte membrane.

Journal: Hepatology (Baltimore, Md.) 20030801

Title: Experimental model of acute pancreatitis in Wistar rat: glucocorticoid treatment profile.

Journal: Digestive diseases and sciences 20030801

Title: Bile acid malabsorption in patients with chronic diarrhoea: clinical value of SeHCAT test.

Journal: Scandinavian journal of gastroenterology 20030801

Title: Functional complementation between a novel mammalian polygenic transport complex and an evolutionarily ancient organic solute transporter, OSTalpha-OSTbeta.

Journal: The Journal of biological chemistry 20030725

Title: Preventive effect of hydrotalcite on gastric mucosal injury in rats induced by taurocholate.

Journal: World journal of gastroenterology 20030715

Title: Identification and characterization of novel rat and human gonad-specific organic anion transporters.

Journal: Molecular endocrinology (Baltimore, Md.) 20030701

Title: ETA and ETB receptor function in pancreatitis-associated microcirculatory failure, inflammation, and parenchymal injury.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20030701

Title: Pancreatic gene expression during the initiation of acute pancreatitis: identification of EGR-1 as a key regulator.

Journal: Physiological genomics 20030624

Title: Inhibition of cholesterol crystallization under bilirubin deconjugation: partial characterization of mechanisms whereby infected bile accelerates pigment stone formation.

Journal: Biochimica et biophysica acta 20030610

Title: Kinetic characterization of carrier-mediated transport systems for D-glucose and taurocholate in the everted sacs of the rat colon.

Journal: Biological & pharmaceutical bulletin 20030601

Title: Selective binding of steroids by 2,2'-biquinoline-4,4'-dicarboxamide-bridged bis(beta-cyclodextrin): fluorescence enhancement by guest inclusion.

Journal: The Journal of organic chemistry 20030502

Title: Taurocholate prevents the loss of intrahepatic bile ducts due to vagotomy in bile duct-ligated rats.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20030501

Title: The role of inducible nitric oxide synthase inhibitor, meropenem, and taurine in experimental acute necrotizing pancreatitis.

Journal: Pancreas 20030501

Title: The effect of antibiotic and probiotic combination therapy on secondary pancreatic infections and oxidative stress parameters in experimental acute necrotizing pancreatitis.

Journal: Pancreas 20030501

Title: Dexamethasone and ursodeoxycholic acid protect against the arrhythmogenic effect of taurocholate in an in vitro study of rat cardiomyocytes.

Journal: BJOG : an international journal of obstetrics and gynaecology 20030501

Title: Fatty acid synthesizing enzymes intrinsic to myelin.

Journal: Brain research. Molecular brain research 20030410

Title: Organic anion transporter 3 (Slc22a8) is a dicarboxylate exchanger indirectly coupled to the Na+ gradient.

Journal: American journal of physiology. Renal physiology 20030401

Title: Retention of transporter activities in cryopreserved, isolated rat hepatocytes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20030401

Title: Multiple alterations of canalicular membrane transport activities in rats with CCl(4)-induced hepatic injury.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20030401

Title: Expression of survivin after acute necrohemorrhagic pancreatitis in rats.

Journal: Pancreas 20030301

Title: Macrophage migration inhibitory factor is a critical mediator of severe acute pancreatitis.

Journal: Gastroenterology 20030301

Title: Transport of taurocholate by mutants of negatively charged amino acids, cysteines, and threonines of the rat liver sodium-dependent taurocholate cotransporting polypeptide Ntcp.

Journal: European journal of biochemistry 20030301

Title: The relative ligand binding preference of the murine ileal lipid binding protein.

Journal: Protein expression and purification 20030301

Title: Effects of bile acids on biliary epithelial cells: proliferation, cytotoxicity, and cytokine secretion.

Journal: Life sciences 20030207

Title: Taurocholate feeding prevents CCl4-induced damage of large cholangiocytes through PI3-kinase-dependent mechanism.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20030201

Title: Substitution of Trp1242 of TM17 alters substrate specificity of human multidrug resistance protein 3.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20030201

Title: Insights into the bile acid transportation system: the human ileal lipid-binding protein-cholyltaurine complex and its comparison with homologous structures.

Journal: Proteins 20030201

Title: A systematic examination of the in vitro Ussing chamber and the in situ single-pass perfusion model systems in rat ileum permeation of model solutes.

Journal: Journal of pharmaceutical sciences 20030201

Title: Active influx transport is mediated by members of the organic anion transporting polypeptide family in human epidermal keratinocytes.

Journal: The Journal of investigative dermatology 20030201

Title: Down-regulation of the Na+/taurocholate cotransporting polypeptide during pregnancy in the rat.

Journal: Journal of hepatology 20030201

Title: Bile acids induce the expression of the human peroxisome proliferator-activated receptor alpha gene via activation of the farnesoid X receptor.

Journal: Molecular endocrinology (Baltimore, Md.) 20030201

Title: Effect of hepatic artery flow on bile secretory function after cold ischemia.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20030201

Title: Buccal delivery of thiocolchicoside: in vitro and in vivo permeation studies.

Journal: International journal of pharmaceutics 20030102

Title: Physiological characteristics of allo-cholic acid.

Journal: Journal of lipid research 20030101

Title: Product ion scanning using a Q-q-Q linear ion trap (Q TRAP) mass spectrometer.

Journal: Rapid communications in mass spectrometry : RCM 20030101

Title: Effects of octreotide pretreatment in experimental acute pancreatitis.

Journal: Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20030101

Title: Prostaglandin E receptor EP1 subtype but not prostacyclin IP receptor involved in mucosal blood flow response of mouse stomachs following barrier disruption.

Journal: Digestion 20030101

Title: The response of bile secretion and ubiquinone Q10 to hyperglycaemia in sheep.

Journal: Polish journal of veterinary sciences 20030101

Title: Regulation of renal tubular bile acid transport in the early phase of an obstructive cholestasis in the rat.

Journal: Nephron. Physiology 20030101

Title: Effect of the dimeric bile acid analogue S 0960, a specific inhibitor of the apical sodium-dependent bile salt transporter in the ileum, on the renal handling of taurocholate.

Journal: Arzneimittel-Forschung 20030101

Title: CbsT2 from Lactobacillus johnsonii 100-100 is a transport protein of the major facilitator superfamily that facilitates bile acid antiport.

Journal: Journal of molecular microbiology and biotechnology 20030101

Title: The role of cholesterol on the pressure sensing ability of kidneys in rats.

Journal: Journal of basic and clinical physiology and pharmacology 20030101

Title: Sinusoidal efflux of taurocholate correlates with the hepatic expression level of Mrp3.

Journal: Biochemical and biophysical research communications 20021220

Title: Identification of a region of the ileal-type sodium/bile acid cotransporter interacting with a competitive bile acid transport inhibitor.

Journal: Biochemistry 20021217

Title: Effect of nitric oxide on the sinusoidal uptake of organic cations and anions by isolated hepatocytes.

Journal: Archives of pharmacal research 20021201

Title: Quantitative evaluation of altered hepatic spaces and membrane transport in fibrotic rat liver.

Journal: Hepatology (Baltimore, Md.) 20021101

Title: The role of transhepatic bile salt flux in the control of hepatic secretion of triacylglycerol-rich lipoproteins in vivo in rodents.

Journal: Biochimica et biophysica acta 20021010

Title: Cholesterol crystallite nucleation in supersaturated model biles from a thermodynamic standpoint.

Journal: Biochimica et biophysica acta 20021009

Title: In vitro versus in vivo cellulose microfibrils from plant primary wall synthases: structural differences.

Journal: The Journal of biological chemistry 20021004

Title: Human macrophage-mediated biodegradation of polyurethanes: assessment of candidate enzyme activities.

Journal: Biomaterials 20021001

Title: Inflammatory cytokines, but not bile acids, regulate expression of murine hepatic anion transporters in endotoxemia.

Journal: The Journal of pharmacology and experimental therapeutics 20021001

Title: Mechanisms for absorption enhancement of inhaled insulin by sodium taurocholate.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20021001

Title: Cholesterol treatment forever? The first Scandinavian trial of cholesterol supplementation in the cholesterol-synthesis defect Smith-Lemli-Opitz syndrome.

Journal: Journal of internal medicine 20021001

Title: Effects of phalloidin on the biliary excretion of cholephilic compounds in rats.

Journal: Pharmacology 20020901

Title: Cathepsin B inhibition prevents trypsinogen activation and reduces pancreatitis severity.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20020901

Title: Protein kinase B/Akt mediates cAMP- and cell swelling-stimulated Na+/taurocholate cotransport and Ntcp translocation.

Journal: The Journal of biological chemistry 20020809

Title: Chirality, twist and structures of micellar lyotropic cholesteric liquid crystals in comparison to the properties of chiralic thermotropic phases.

Journal: Advances in colloid and interface science 20020805

Title: Gender difference in the urinary excretion of organic anions in rats.

Journal: The Journal of pharmacology and experimental therapeutics 20020801

Title: Taurocholate induces changes in rat cardiomyocyte contraction and calcium dynamics.

Journal: Clinical science (London, England : 1979) 20020801

Title: Impaired organic anion transport in kidney and choroid plexus of organic anion transporter 3 (Oat3 (Slc22a8)) knockout mice.

Journal: The Journal of biological chemistry 20020726

Title: Different interactions of egg-yolk phosphatidylcholine and sphingomyelin with detergent bile salts.

Journal: Biochimica et biophysica acta 20020711

Title: Effects of hydrophobic and hydrophilic bile salt mixtures on cholesterol crystallization in model biles.

Journal: Biochimica et biophysica acta 20020711

Title: Incorporation of cholesterol in sphingomyelin- phosphatidylcholine vesicles has profound effects on detergent-induced phase transitions.

Journal: Journal of lipid research 20020701

Title: Gastric nitric oxide synthase expression during endotoxemia: implications in mucosal defense in rats.

Journal: Gastroenterology 20020701

Title: Inhibition of transport across the hepatocyte canalicular membrane by the antibiotic fusidate.

Journal: Biochemical pharmacology 20020701

Title: Splanchnic and pancreatic tissue perfusion in experimental acute pancreatitis.

Journal: Scandinavian journal of gastroenterology 20020701

Title: Regulation of oxysterol 7alpha-hydroxylase (CYP7B1) in primary cultures of rat hepatocytes.

Journal: Hepatology (Baltimore, Md.) 20020601

Title: Differential effects of streptozotocin-induced diabetes on expression of hepatic ABC-transporters in rats.

Journal: Gastroenterology 20020601

Title: Effects of high taurocholate load on activities of hepatic alcohol metabolizing enzymes.

Journal: Experimental & molecular medicine 20020531

Title: Intraduodenal conjugated bile salts exert negative feedback control on gall bladder emptying in the fasting state without affecting cholecystokinin release or antroduodenal motility.

Journal: Gut 20020501

Title: Gastric hyperemic response induced by acid back-diffusion in rat stomachs following barrier disruption -- relation to vanilloid type-1 receptors.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20020501

Title: Effect of hydrochloric acid, pepsin, or taurocholate on bioelectric properties of gastric squamous mucosa in horses.

Journal: American journal of veterinary research 20020501

Title: Chiral separation of amino acids derivatized with fluoresceine-5isothiocyanate by capillary electrophoresis and laser-induced fluorescence detection using mixed selectors of beta-cyclodextrin and sodium taurocholate.

Journal: Journal of chromatography. A 20020426

Title: Dapsone-induced cholestasis and impairment of bile salt output in the rat.

Journal: Biochemical pharmacology 20020415

Title: An evolutionarily ancient Oatp: insights into conserved functional domains of these proteins.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20020401

Title: An ultraviolet spectrophotometric assay for measuring lipase activity using long-chain triacyglycerols from Aleurites fordii seeds.

Journal: Analytical biochemistry 20020401

Title: Quantitation of cholesterol crystallization from supersaturated model bile.

Journal: Journal of lipid research 20020401

Title: Levels of thermostable direct hemolysin produced by Vibrio parahaemolyticus O3:K6 and other serovars grown anaerobically with the presence of a bile acid.

Journal: Current microbiology 20020401

Title: Gastric ulcerogenic responses following barrier disruption in knockout mice lacking prostaglandin EP1 receptors.

Journal: Alimentary pharmacology & therapeutics 20020401

Title: Characteristics of lysophosphatidylcholine in its inhibition of taurine uptake by human intestinal Caco-2 cells.

Journal: Bioscience, biotechnology, and biochemistry 20020401

Title: Combination of lipids and emulsifiers enhances the absorption of orally administered quercetin in rats.

Journal: Journal of agricultural and food chemistry 20020313

Title: Human interleukin 10 gene therapy decreases the severity and mortality of lethal pancreatitis in rats.

Journal: The Journal of surgical research 20020301

Title: Forecasting the oral absorption behavior of poorly soluble weak bases using solubility and dissolution studies in biorelevant media.

Journal: Pharmaceutical research 20020301

Title: [Interactions of unconjugated bilirubin with bile acid by rapid solvent partition].

Journal: Taehan Kan Hakhoe chi = The Korean journal of hepatology 20020301

Title: A physicochemical investigation of two phosphatidylcholine/bile salt interfaces: implications for lipase activation.

Journal: Biochimica et biophysica acta 20020227

Title: Inhibition of Mrp2- and Ycf1p-mediated transport by reducing agents: evidence for GSH transport on rat Mrp2.

Journal: Biochimica et biophysica acta 20020215

Title: Effect of 17 beta-estradiol-D-17 beta-glucuronide on the rat organic anion transporting polypeptide 2-mediated transport differs depending on substrates.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20020201

Title: In vitro determination of active bile acid absorption in small biopsy specimens obtained endoscopically or surgically from the human intestine.

Journal: European journal of clinical investigation 20020201

Title: Effects of Cys mutation on taurocholic acid transport by mouse ileal and hepatic sodium-dependent bile acid transporters.

Journal: Bioscience, biotechnology, and biochemistry 20020201

Title: Active taurocholic acid flux through hepatoma cells increases the cellular pool of unesterified cholesterol derived from lipoproteins.

Journal: Biochimica et biophysica acta 20020130

Title: pH-dependent interaction of fumonisin B1 with cholesterol: physicochemical and molecular modeling studies at the air-water interface.

Journal: Journal of agricultural and food chemistry 20020116

Title: The effects of hypo- and hyperthermic pretreatment on sodium taurocholate-induced acute pancreatitis in rats.

Journal: Pancreas 20020101

Title: Micellar electrokinetic capillary chromatography determination of +S and -R arotinolol in serum using UV detection and solid phase extraction.

Journal: Chirality 20020101

Title: Increased expression of ileal apical sodium-dependent bile acid transporter in postpartum rats.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20020101

Title: Role of extrinsic innervation in jejunal absorptive adaptation to subtotal small bowel resection: a model of segmental small bowel transplantation.

Journal: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20020101

Title: Role of bile acids in lymphocytic colitis.

Journal: Hepato-gastroenterology 20020101

Title: Effects of octreotide on lipid peroxidation in pancreas and plasma in acute hemorrhagic necrotizing pancreatitis in rats.

Journal: Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20020101

Title: Modulation of absorption of beta-carotene and tissue accumulation of beta-carotene and vitamin A by different surfactants in rats.

Journal: Annals of nutrition & metabolism 20020101

Title: Has the oxidative stress a role in late phase of experimental acute necrotizing pancreatitis?

Journal: Hepato-gastroenterology 20020101

Title: [The influence of select pathophysiologic factors of acute pancreatitis on erythrocytes' deformability examined in vitro].

Journal: Wiadomosci lekarskie (Warsaw, Poland : 1960) 20020101

Title: Shift of zinc in serum and tissues in course of experimental acute pancreatitis.

Journal: Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina 20020101

Title: Lipolytic and esterolytic activities in posterior lingual glands of rat: a histochemical study.

Journal: The Histochemical journal 20020101

Title: Endogenous neurotensin facilitates enterohepatic bile acid circulation by enhancing intestinal uptake in rats.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20011201

Title: Production of the mycelial phase of Malassezia in vitro.

Journal: Medical mycology 20011201

Title: Role of nonesterified fatty acids in necrotizing pancreatitis: an in vivo experimental study in rats.

Journal: Pancreas 20011101

Title: Bile-salt hydrophobicity is a key factor regulating rat liver plasma-membrane communication: relation to bilayer structure, fluidity and transporter expression and function.

Journal: The Biochemical journal 20011101

Title: Bile acid feeding increased proliferative activity and apical bile acid transporter expression in both small and large rat cholangiocytes.

Journal: Hepatology (Baltimore, Md.) 20011101

Title: [Enzymatic and histological alterations in the isolated perfused rat pancreas in the taurocholate and cerulein model of acute pancreatitis].

Journal: Zentralblatt fur Chirurgie 20011101

Title: Distribution and diffusion of sodium taurocholate and egg phosphatidylcholine aggregates in rat intestinal mucin.

Journal: Pharmaceutical research 20011101

Title: Helicobacter pylori, N-methyl-N'-nitro-N'-nitrosoguanidine, and bile modulate gastric cell kinetics in experimental cancer.

Journal: Virchows Archiv : an international journal of pathology 20011101

Title: Effects of Helicobacter pylori and bile on N-methyl-N'-nitro-N'-nitrosoguanidine exposed antral mucosa of C57BU6 mice.

Journal: Virchows Archiv : an international journal of pathology 20011101

Title: Indirect evidence that intestinal bile salt absorption in rats and hamsters is under positive feedback control.

Journal: Zeitschrift fur Gastroenterologie 20011101

Title: Troglitazone-induced intrahepatic cholestasis by an interference with the hepatobiliary export of bile acids in male and female rats. Correlation with the gender difference in troglitazone sulfate formation and the inhibition of the canalicular bile salt export pump (Bsep) by troglitazone and troglitazone sulfate.

Journal: Toxicology 20011005

Title: Common mechanisms of monoacylglycerol and fatty acid uptake by human intestinal Caco-2 cells.

Journal: American journal of physiology. Cell physiology 20011001

Title: Single amino acid substitution of rat MRP2 results in acquired transport activity for taurocholate.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20011001

Title: The effect of a functional group in penicillin derivatives on the interaction with bile salt micelles studied by micellar electrokinetic chromatography.

Journal: Electrophoresis 20011001

Title: Pericentral hepatocytes translocate hydrophilic bile acids more rapidly than hydrophobic ones.

Journal: Digestive diseases and sciences 20011001

Title: The utilization of sodium taurocholate in excystation of Cryptosporidium parvum and infection of tissue culture.

Journal: The Journal of parasitology 20011001

Title: Nuclear receptor-mediated repression of human cholesterol 7alpha-hydroxylase gene transcription by bile acids.

Journal: Journal of lipid research 20010901

Title: Ezetimibe selectively inhibits intestinal cholesterol absorption in rodents in the presence and absence of exocrine pancreatic function.

Journal: British journal of pharmacology 20010901

Title: Alkaline phosphatase from rat liver and kidney is differentially modulated.

Journal: Clinical biochemistry 20010901

Title: Pancreatic tissue perfusion in experimental acute pancreatitis.

Journal: The European journal of surgery = Acta chirurgica 20010901

Title: Effects of internal biliary bypass on the regulation of hepatic cholesterol 7alpha-hydroxylase activity in rats.

Journal: Steroids 20010801

Title: Bile salt export pump is highly conserved during vertebrate evolution and its expression is inhibited by PFIC type II mutations.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20010801

Title: Interrelationship between colonic muscularis mucosae activity and changes in transmucosal potential difference.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20010801

Title: Beneficial effects of growth hormone on bacterial translocation during the course of acute necrotizing pancreatitis in rats.

Journal: Pancreas 20010801

Title: Intracellular glutathione regulates taurocholate transport in HepG2 cells.

Journal: Toxicology and applied pharmacology 20010801

Title: Tauroursodesoxycholate-induced choleresis involves p38(MAPK) activation and translocation of the bile salt export pump in rats.

Journal: Gastroenterology 20010801

Title: Sinusoidal efflux of taurocholate is enhanced in Mrp2-deficient rat liver.

Journal: Pharmaceutical research 20010801

Title: Characterization of the efflux transport of 17beta-estradiol-D-17beta-glucuronide from the brain across the blood-brain barrier.

Journal: The Journal of pharmacology and experimental therapeutics 20010701

Title: Anti-ICAM-1 antibody modulates late onset of acinar cell apoptosis and early necrosis in taurocholate-induced experimental acute pancreatitis.

Journal: Pancreas 20010701

Title: Analysis of the diffusion of bile salt/phospholipid micelles in rat intestinal mucin.

Journal: Chemistry and physics of lipids 20010701

Title: Localized pancreatic NF-kappaB activation and inflammatory response in taurocholate-induced pancreatitis.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20010601

Title: Cellular distribution and handling of liver-targeting preparations in human livers studied by a liver lobe perfusion.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20010601

Title: Human liver-specific organic anion transporter, LST-1, mediates uptake of pravastatin by human hepatocytes.

Journal: The Journal of pharmacology and experimental therapeutics 20010601

Title: Adaptive gastric cytoprotection is mediated by prostaglandin EP1 receptors: a study using rats and knockout mice.

Journal: The Journal of pharmacology and experimental therapeutics 20010601

Title: Characterization of model bile using fluorescence energy transfer from dehydroergosterol to dansylated lecithin.

Journal: Journal of lipid research 20010601

Title: Long-term course in collagenous colitis and the impact of bile acid malabsorption and bile acid sequestrants on histopathology and clinical features.

Journal: Scandinavian journal of gastroenterology 20010601

Title: Obesity increases the severity of acute experimental pancreatitis in the rat.

Journal: Scandinavian journal of gastroenterology 20010601

Title: Optimization of culture conditions for determining hepatobiliary disposition of taurocholate in sandwich-cultured rat hepatocytes.

Journal: In vitro cellular & developmental biology. Animal 20010601

Title: Taurocholic acid-induced secretion in normal and cystic fibrosis mouse ileum.

Journal: The Journal of pharmacy and pharmacology 20010501

Title: Mechanisms for the transport of unconjugated bilirubin in human trophoblastic BeWo cells.

Journal: FEBS letters 20010420

Title: The bile acid taurocholate impairs rat cardiomyocyte function: a proposed mechanism for intra-uterine fetal death in obstetric cholestasis.

Journal: Clinical science (London, England : 1979) 20010401

Title: Cellular distribution and handling of liver-targeting preparations in human livers studied by a liver lobe perfusion.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20010401

Title: The endothelin antagonist bosentan inhibits the canalicular bile salt export pump: a potential mechanism for hepatic adverse reactions.

Journal: Clinical pharmacology and therapeutics 20010401

Title: In vitro taurocholate-induced segmentation and clustering of Mesocestoides vogae (syn. corti) tetrathyridia (Cestoda)--inhibition byh cestocidal drugs.

Journal: Parasitology research 20010401

Title: Identification of the bile acid-binding site of the ileal lipid-binding protein by photoaffinity labeling, matrix-assisted laser desorption ionization-mass spectrometry, and NMR structure.

Journal: The Journal of biological chemistry 20010309

Title: Transporters on demand: intrahepatic pools of canalicular ATP binding cassette transporters in rat liver.

Journal: The Journal of biological chemistry 20010309

Title: Characterization of bile acid transport mediated by multidrug resistance associated protein 2 and bile salt export pump.

Journal: Biochimica et biophysica acta 20010309

Title: The rat liver Na(+)/bile acid cotransporter. Importance of the cytoplasmic tail to function and plasma membrane targeting.

Journal: The Journal of biological chemistry 20010302

Title: Differences in Ca(2+) signaling underlie age-specific effects of secretagogues on colonic Cl(-) transport.

Journal: American journal of physiology. Cell physiology 20010301

Title: Cholestatic potential of troglitazone as a possible factor contributing to troglitazone-induced hepatotoxicity: in vivo and in vitro interaction at the canalicular bile salt export pump (Bsep) in the rat.

Journal: Molecular pharmacology 20010301

Title: Hemodynamic and metabolic variables predict porcine ex vivo liver function.

Journal: The Journal of surgical research 20010301

Title: Interleukin-10 attenuates proinflammatory cytokine production and improves survival in lethal pancreatitis.

Journal: The American surgeon 20010301

Title: A simple method for measuring of intestinal solute transport in mucosal biopsy specimens.

Journal: Digestive diseases and sciences 20010301

Title: Identification of novel hypocholesterolemic peptides derived from bovine milk beta-lactoglobulin.

Journal: Biochemical and biophysical research communications 20010216

Title: Effect of bile acids on the uptake of irinotecan and its active metabolite, SN-38, by intestinal cells.

Journal: Biochimica et biophysica acta 20010216

Title: Minor role of oxidative stress during intermediate phase of acute pancreatitis in rats.

Journal: Free radical biology & medicine 20010201

Title: Kinetics characterization of taurocholic transport in Lactobacillus reuteri.

Journal: Current microbiology 20010101

Title: Urinary excretion of trypsinogen activation peptide (TAP) in taurocholate-induced pancreatitis in rats.

Journal: Pancreas 20010101

Title: Enhancement of jejunal absorption of conjugated bile acid by neurotensin in rats.

Journal: Gastroenterology 20010101

Title: Interaction of bile salt and phospholipids with bovine submaxillary mucin.

Journal: Pharmaceutical research 20010101

Title: Design and properties of hepatitis C virus antisense oligonucleotides for liver specific drug targeting.

Journal: Nucleosides, nucleotides & nucleic acids 20010101

Title: The effect of etodolac on bile salt and histamine-mediated gastric mucosal injury in the rat.

Journal: Journal of physiology, Paris 20010101

Title: Role of endogenous prostacyclin in gastric ulcerogenic and healing responses--a study using IP-receptor knockout mice.

Journal: Journal of physiology, Paris 20010101

Title: Ileal mucosal bile acid absorption is increased in Cftr knockout mice.

Journal: BMC gastroenterology 20010101

Title: Expression of proteinase-activated receptor 2 during taurocholate-induced acute pancreatic lesion development in Wistar rats.

Journal: International journal of gastrointestinal cancer 20010101

Title: Functional and histochemical analysis of MDR3 P-glycoprotein in a tetracycline-controlled gene expression system.

Journal: European journal of medical research 20001229

Title: Mrp2 is essential for estradiol-17beta(beta-D-glucuronide)-induced cholestasis in rats.

Journal: Hepatology (Baltimore, Md.) 20000701

Title: Immunohistochemical and functional characterization of pH-dependent intestinal absorption of weak organic acids by the monocarboxylic acid transporter MCT1.

Journal: The Journal of pharmacy and pharmacology 19991001

Title: Characterization of cholyl-adenylate in rat liver microsomes by liquid chromatography/electrospray ionization-mass spectrometry.

Journal: Analytical biochemistry 19990101

Title: Substrate specificity of the rat liver Na(+)-bile salt cotransporter in Xenopus laevis oocytes and in CHO cells.

Journal: The American journal of physiology 19980201

Title: Expression and transport properties of the human ileal and renal sodium-dependent bile acid transporter.

Journal: The American journal of physiology 19980101

Title: Bile acid stimulation of early growth response gene and mitogen-activated protein kinase is protein kinase C-dependent.

Journal: The Biochemical journal 19960615

Title: Cyclosporin A-mediated cholestasis in patients with chronic hepatitis after heart transplantation.

Journal: European journal of gastroenterology & hepatology 19960301

Title: Suppression of sterol 27-hydroxylase mRNA and transcriptional activity by bile acids in cultured rat hepatocytes.

Journal: The Biochemical journal 19950115

Title: Therapeutic index of taurocholate or tauroursodeoxycholate in experimental drug-induced cholestasis.

Journal: The Italian journal of gastroenterology 19950101

Title: Capsaicin-induced gastric hyperemia and protection are NO- dependent.

Journal: The Journal of surgical research 19941001

Title: Synthesis and biological activity of bile acid-derived HMG-CoA reductase inhibitors. The role of 21-methyl in recognition of HMG-CoA reductase and the ileal bile acid transport system.

Journal: Journal of medicinal chemistry 19940930

Title: Cholestasis caused by inhibition of the adenosine triphosphate-dependent bile salt transport in rat liver.

Journal: Gastroenterology 19940701

Title: Ethinylestradiol treatment induces multiple canalicular membrane transport alterations in rat liver.

Journal: The Journal of clinical investigation 19930601

Title: Zonal changes of hepatobiliary taurocholate transport in intrahepatic cholestasis induced by 17 alpha-ethinyl estradiol: a histoautoradiographic study in rats.

Journal: Hepatology (Baltimore, Md.) 19930301

Title: Effect of epomediol on taurocholate uptake in hepatocytes isolated from normal rats or rats with ethinyloestradiol-induced cholestasis.

Journal: Pharmacology & toxicology 19930101

Title: Effects of bile salt infusion on chlorpromazine-induced cholestasis in the isolated perfused rat liver.

Journal: Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 19920101

Title: Increased paracellular permeability in intrahepatic cholestasis induced by carmustine (BCNU) in rats.

Journal: Gastroenterology 19910701

Title: Failure of secretin to increase sodium taurocholate-induced pancreatic necrosis in alcoholic rats.

Journal: European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 19910101

Title: Estradiol-17 beta-D-glucuronide (E-17G) cholestasis in perfused rat liver: fate of E-17G and choleretic responses to bile salts.

Journal: Hepatology (Baltimore, Md.) 19900501

Title: Characterization of a transporting system in rat hepatocytes. Studies with competitive and non-competitive inhibitors of phalloidin transport.

Journal: Biochimica et biophysica acta 19860807

Title: Biliary permeability during ethinyl estradiol-induced cholestasis studied by segmented retrograde intrabiliary injections in rats.

Journal: Journal of hepatology 19850101

Title: Hepatocyte taurocholic acid uptake in the regression of ethinyl estradiol cholestasis. Preliminary results.

Journal: Bollettino della Societa italiana di biologia sperimentale 19840330

Title: Experimental models for gastric leiomyosarcoma. The effects of N-methyl-N'-nitro-N-nitrosoguanidine in combination with stress, aspirin, or sodium taurocholate.

Journal: Cancer 19840301

Title: Cholestasis induced by estradiol-17 beta-D-glucuronide: mechanisms and prevention by sodium taurocholate.

Journal: Hepatology (Baltimore, Md.) 19840101

Title: Hepatic handling of bile salts and protein in the rat during intrahepatic cholestasis.

Journal: Gastroenterology 19830501

Title: Effects of chlorpromazine hydrochloride on bile salt synthesis, bile formation and biliary lipid secretion in the rhesus monkey: a model for chlorpromazine-induced cholestasis.

Journal: European journal of clinical investigation 19790201

Title: Microsomal membrane permeability and the hepatic glucose-6-phosphatase system. Interactions of the system with D-mannose 6-phosphate and D-mannose.

Journal: The Journal of biological chemistry 19760825

Title: Effects of colipase and taurodeoxycholate on the catalytic and physical properties of pancreatic lipase B at an oil water interface.

Journal: The Journal of biological chemistry 19760125

Title: Enzymatic synthesis of cholyl coA and taurocholic acid.

Journal: Science (New York, N.Y.) 19560302

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Tags:145-42-6 Molecular Formula|145-42-6 MDL|145-42-6 SMILES|145-42-6 Monosodium taurocholate