Home Other Building Blocks 2958-04-5
2958-04-5,MFCD00907891
Catalog No.:AA00C2QF

2958-04-5 | taurohyodeoxycholic acid

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Purity
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100mg
95%
in stock  
$411.00   $288.00
- +
250mg
95%
in stock  
$809.00   $567.00
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1g
95%
in stock  
$2,007.00   $1,405.00
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00C2QF
Chemical Name:
taurohyodeoxycholic acid
CAS Number:
2958-04-5
Molecular Formula:
C26H45NO6S
Molecular Weight:
499.7036
MDL Number:
MFCD00907891
SMILES:
O[C@@H]1CC[C@]2([C@@H](C1)[C@@H](O)C[C@@H]1[C@@H]2CC[C@]2([C@H]1CC[C@@H]2[C@@H](CCC(=O)NCCS(=O)(=O)O)C)C)C
Properties
Computed Properties
 
Complexity:
858  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
10  
Heavy Atom Count:
34  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
7  
XLogP3:
3.6  

Literature

Title: Organic anion transporting polypeptide 1a1 null mice are sensitive to cholestatic liver injury.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20120601

Title: Protective effect of taurohyodeoxycholic acid from Pulvis Fellis Suis on trinitrobenzene sulfonic acid induced ulcerative colitis in mice.

Journal: European journal of pharmacology 20111116

Title: Novel potent and selective bile acid derivatives as TGR5 agonists: biological screening, structure-activity relationships, and molecular modeling studies.

Journal: Journal of medicinal chemistry 20080327

Title: Taurohyodeoxycholate- and tauroursodeoxycholate-induced hypercholeresis is augmented in bile duct ligated rats.

Journal: Journal of hepatology 20030201

Title: Comparative cytotoxic and cytoprotective effects of taurohyodeoxycholic acid (THDCA) and tauroursodeoxycholic acid (TUDCA) in HepG2 cell line.

Journal: Biochimica et biophysica acta 20020130

Title: Effect of chronic administration of tauro-hyodeoxycholic acid on biliary bile acid composition and on biliary lipid secretion in humans.

Journal: Scandinavian journal of gastroenterology 20010901

Title: Roda A, et, al. Taurohyodeoxycholic acid protects against taurochenodeoxycholic acid-induced cholestasis in the rat. Hepatology. 1998 Feb;27(2):520-5.

Title: Carubbi F, et, al. Comparative cytotoxic and cytoprotective effects of taurohyodeoxycholic acid (THDCA) and tauroursodeoxycholic acid (TUDCA) in HepG2 cell line. Biochim Biophys Acta. 2002 Jan 30;1580(1):31-9.

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Tags:2958-04-5 Molecular Formula|2958-04-5 MDL|2958-04-5 SMILES|2958-04-5 taurohyodeoxycholic acid